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Your search keyword '"Satre, E. P."' showing total 3 results
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3 results on '"Satre, E. P."'

1. French Previously Untreated Patients with Severe Hemophilia A after Exposure to Recombinant Factor VIII : Incidence of Inhibitor and Evaluation of Immune Tolerance

Author

Laurian, Y., primary, Satre, E. P., primary, Derlon, A. Borel, primary, Chambost, H., primary, Moreau, P., primary, Goudemand, J., primary, Parquet, A., primary, Peynet, J., primary, Vicariot, M., primary, Beurrier, P., primary, Claeyssens, S., primary, Durin, A., primary, Faradji, A., primary, Fressinaud, E., primary, Gaillard, S., primary, Guérin, V., primary, Guérois, C., primary, Pernod, G., primary, Pouzol, P., primary, Schved, J. F., primary, Gazengel, C., primary, and Rothschild, C., additional

Published
1998
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2. French Previously Untreated Patients with Severe Hemophilia A after Exposure to Recombinant Factor VIII : Incidence of Inhibitor and Evaluation of Immune Tolerance

Author

Rothschild, C., Laurian, Y., Satre, E. P., Derlon, A. Borel, Chambost, H., Moreau, P., Goudemand, J., Parquet, A., Peynet, J., Vicariot, M., Beurrier, P., Claeyssens, S., Durin, A., Faradji, A., Fressinaud, E., Gaillard, S., Guérin, V., Guérois, C., Pernod, G., Pouzol, P., Schved, J. F., and Gazengel, C.

Published
1998
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3. No evidence of HIV-1 infection in seronegative hemophiliacs and in seronegative partners of seropositive hemophiliacs through polymerase chain reaction (PCR) and anti-NEF serology.

Author

Ferrer-Le-Coeur F, Mariotti M, Hivert P, Satre EP, Bouchardeau F, Couroucé AM, Rouger P, and Lefrère JJ

Subjects
Base Sequence, Blotting, Western, Female, Gene Products, nef immunology, HIV Infections complications, HIV Seropositivity complications, Humans, Male, Molecular Sequence Data, Polymerase Chain Reaction, Prospective Studies, Risk Factors, nef Gene Products, Human Immunodeficiency Virus, HIV Infections diagnosis, HIV Seropositivity microbiology, HIV-1 isolation & purification, Hemophilia A complications, Sexual Partners
Abstract

We prospectively studied a well-characterized cohort including 60 seronegative hemophiliacs or von Willebrand's disease patients, 6 seronegative female sexual partners of seropositive hemophiliacs, 59 seropositive hemophiliacs or von Willebrand's disease patients and 2 seropositive partners of seropositive hemophiliacs (used as positive controls), and 117 seronegative low risk individuals (used as negative controls). PCR assay, performed in peripheral blood mononuclear cells using three primer pairs in the gag, pol, LTR regions, showed no positive results in the 60 seronegative patients, in the 6 seronegative partners of seropositive patients and in the 117 seronegative low risk individuals, while PCR was positive with at least one primer pair in 53 (87%) of 61 seropositive patients. Anti-nef serology (Western-blot) was negative in seronegative patients, in seronegative partners of seropositive patients and positive in 58% out of the seropositive individuals. These results strongly suggest an absence of HIV-1 infection in individuals with a lastingly negative HIV serology.

Published
1991

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