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2. Thrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort study

Author

Levy, David, Saura, Ouriel, Passarelli, Maria Teresa, Lucenteforte, Manuela, Lebreton, Guillaume, Bougle, Adrien, Monsel, Antoine, Ortuno, Sofia, Benitha, Yoël, Hammoudi, Nadjib, Assouline, Benjamin, Petit, Matthieu, Gautier, Melchior, Le Fevre, Lucie, Pineton de Chambrun, Marc, Juvin, Charles, Chommeloux, Juliette, Luyt, Charles-Edouard, Hékimian, Guillaume, Leprince, Pascal, Combes, Alain, and Schmidt, Matthieu

Published
2024
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3. Peripheral-to-central extracorporeal corporeal membrane oxygenation switch in refractory cardiogenic shock patients: outcomes and bridging strategies

Author

Besnard, Aurélie, Moyon, Quentin, Lebreton, Guillaume, Demondion, Pierre, Hékimian, Guillaume, Chommeloux, Juliette, Petit, Matthieu, Gautier, Melchior, Lefevre, Lucie, Saura, Ouriel, Levy, David, Schmidt, Matthieu, Leprince, Pascal, Luyt, Charles-Edouard, Combes, Alain, and Pineton de Chambrun, Marc

Published
2024
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8. Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support

Author

Marquet, Yann, Hékimian, Guillaume, Lebreton, Guillaume, Kerneis, Mathieu, Rouvier, Philippe, Bay, Pierre, Mathian, Alexis, Bréchot, Nicolas, Chommeloux, Juliette, Petit, Matthieu, Gautier, Melchior, Lefevre, Lucie, Saura, Ouriel, Levy, David, Quentric, Paul, Moyon, Quentin, Ortuno, Sofia, Schmidt, Matthieu, Leprince, Pascal, Luyt, Charles-Edouard, Combes, Alain, and Pineton de Chambrun, Marc

Published
2023
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9. Management of renal replacement therapy among adults in French intensive care units: A bedside practice evaluation

Author

Megarbane, Bruno, Lesieur, Olivier, Leloup, Maxime, Weiss, Nicolas, Tamion, Fabienne, Beuret, Pascal, Monchi, Mehran, Delcourte, Claire, Hayon, Jan, Klouche, Kada, Stoclin, Annabelle, Gibot, Sébastien, Peigne, Vincent, Mezher, Chaouki, Martino, Frédéric, Nguyen, Maxime, Kuteifan, Khaldoun, Louis, Guillaume, Rigault, Guillaume, Masuccio, Michel, Garin, Aude, Asfar, Pierre, Andrieu, Maude, Auchabie, Johann, Daviet, Florence, Lacave, Guillaume, Benhamida, Hotman, Vivet, Bérengère, Chaignat, Claire, Desgrouas, Maxime, La-Combe, Béatrice, Plouvier, Fabienne, Richard, Jean-Christophe, Haddadi, Clément, Czolnowski, Dorian, Lau, Nicolas, Jacobs, Frédéric, Thirion, Marina, Pons, Antoine, Pichon, Nicolas, Patrigeon, René-Gilles, Vieillard-Baron, Antoine, Uhel, Fabrice, Rigaud, Jean-Philippe, Bouhake, Yannis, Zagozda, Dominique, Arrestier, Romain, Vinclair, Camille, Fedou, Anne-Laure, Dargent, Auguste, Dellamonica, Jean, Rey, Brice, Gachet, Alexandre, Serie, Mathieu, Bruel, Cédric, Troger, Antoine, Berthoud, Vivien, Delbove, Agathe, Goulenok, Cyril, Bouguoin, Wulfran, Osman, David, Anguel, Nadia, Guerin, Laurent, Foucault, Camille, Preau, Sébastien, Saura, Ouriel, Boue, Yvonnick, Sedillot, Nicholas, Covin, Laetitia, Lambiotte, Fabien, Guignon, Carole, Perinel-Ragey, Sophie, Souloy, Xavier, Defaux-Chevillard, Cécile, Renault, Anne, Mme-Ngapmen, Nadège, Jourdain, Mercedes, Van Der Linden, Thierry, Levy, Clémentine, Thouy, François, Degouy, Guillaume, Jolly, Florian, Jacquier, Marine, Pecqueur, Delphine, Labruyère, Marie, Vinsonneau, Christophe, Fournel, Isabelle, and Quenot, Jean-Pierre

Published
2023
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10. Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

Author

Aissi James, Sarah, Guervilly, Christophe, Lesouhaitier, Mathieu, Coppens, Alexandre, Haddadi, Clément, Lebreton, Guillaume, Nizard, Jacky, Brechot, Nicolas, Assouline, Benjamin, Saura, Ouriel, Levy, David, Lefèvre, Lucie, Barhoum, Pétra, Chommeloux, Juliette, Hékimian, Guillaume, Luyt, Charles-Edouard, Kimmoun, Antoine, Combes, Alain, and Schmidt, Matthieu

Published
2022
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11. Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study

Author

Saura, Ouriel, Rouzé, Anahita, Martin-Loeches, Ignacio, Povoa, Pedro, Kreitmann, Louis, Torres, Antoni, Metzelard, Matthieu, Du Cheyron, Damien, Lambiotte, Fabien, Tamion, Fabienne, Labruyere, Marie, Boulle Geronimi, Claire, Luyt, Charles-Edouard, Nyunga, Martine, Pouly, Olivier, Thille, Arnaud W., Megarbane, Bruno, Saade, Anastasia, Magira, Eleni, Llitjos, Jean-François, Ioannidou, Iliana, Pierre, Alexandre, Reignier, Jean, Garot, Denis, Baudel, Jean-Luc, Voiriot, Guillaume, Plantefeve, Gaëtan, Morawiec, Elise, Asfar, Pierre, Boyer, Alexandre, Mekontso-Dessap, Armand, Bardaka, Fotini, Diaz, Emili, Vinsonneau, Christophe, Floch, Pierre-Edouard, Weiss, Nicolas, Ceccato, Adrian, Artigas, Antonio, Nora, David, Duhamel, Alain, Labreuche, Julien, and Nseir, Saad

Published
2022
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12. Isoproterenol improves hemodynamics and right ventricle-pulmonary artery coupling after heart transplantation.

Author

Levy, David, Saura, Ouriel, Lucenteforte, Manuela, Lledó, Elena Collado, Demondion, Pierre, Hammoudi, Nadjib, Assouline, Benjamin, Petit, Matthieu, Gautier, Melchior, Fevre, Lucie Le, Chambrun, Marc Pineton de, Coutance, Guillaume, Berg, Elodie, Chommeloux, Juliette, Schmidt, Matthieu, Luyt, Charles-Edouard, Lebreton, Guillaume, Leprince, Pascal, Hékimian, Guillaume, and Combes, Alain

Subjects
*HEART transplantation, *ISOPROTERENOL, *HEMODYNAMICS, *EXTRACORPOREAL membrane oxygenation, *VENTRICULAR ejection fraction
Abstract

Right ventricular failure (RVF) is a major cause of early mortality after heart transplantation (HT). Isoproterenol (Iso) has chronotropic, inotropic, and vasodilatory properties, which might improve right ventricle function in this setting. We aimed to investigate the hemodynamic effects of isoproterenol on patients with post-HT RVF. We conducted a 1-yr retrospective observational study including patients receiving isoproterenol (Iso) and dobutamine for early RVF after HT. A comprehensive multiparametric hemodynamic evaluation was performed successively three times: no isoproterenol, low doses: 0.025 µg/kg/min, and high doses: 0.05 µg/kg/min (henceforth, respectively, called no Iso, low Iso, and high Iso). From June 2022 to June 2023, 25 patients, median [interquartile range (IQR) 25–75] age 54 [38–61] yr, were included. Before isoproterenol was introduced, all patients received dobutamine, and 15 (60%) were on venoarterial extracorporeal membrane oxygenation (VA-ECMO). Isoproterenol significantly increased heart rate from 84 [77–99] (no Iso) to 91 [88–106] (low Iso) and 102 [90–122] beats/min (high Iso, P < 0.001). Similarly, cardiac index rose from 2.3 [1.4–3.1] to 2.7 [1.8–3.4] and 3 [1.9–3.7] L/min/m2 (P < 0.001) with a concomitant increase in indexed stroke volume (28 [17–34] to 31 [20–34] and 33 [23–35] mL/m2, P < 0.05). Effective pulmonary arterial elastance and pressures were not modified by isoproterenol. Pulmonary vascular resistance (PVR) tended to decrease from 2.9 [1.4–3.6] to 2.3 [1.3–3.5] wood units (WU), P = 0.06. Right ventricular ejection fraction/systolic pulmonary artery pressure (sPAP) evaluating right ventricle-pulmonary artery (RV-PA) coupling increased after isoproterenol from 0.8 to 0.9 and 1%·mmHg−1 (P = 0.001). In conclusion, in post-HT RVF, isoproterenol exhibits chronotropic and inotropic effects, thereby improving RV-PA coupling and resulting in a clinically relevant increase in the cardiac index. NEW & NOTEWORTHY: This study offers a detailed and comprehensive hemodynamic investigation at the bedside, illustrating the favorable impact of isoproterenol on right ventricular-pulmonary arterial coupling and global hemodynamics. It elucidates the physiological effects of an underused inotropic strategy in a critical clinical scenario. By enhancing cardiac hemodynamics, isoproterenol has the potential to expedite right ventricular recovery and mitigate primary graft dysfunction, thereby reducing the duration of mechanical support and intensive care unit stay posttransplantation. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Management of renal replacement therapy among adults in French intensive care units: A bedside practice evaluation

Author

Jolly, Florian, primary, Jacquier, Marine, additional, Pecqueur, Delphine, additional, Labruyère, Marie, additional, Vinsonneau, Christophe, additional, Fournel, Isabelle, additional, Quenot, Jean-Pierre, additional, Megarbane, Bruno, additional, Lesieur, Olivier, additional, Leloup, Maxime, additional, Weiss, Nicolas, additional, Tamion, Fabienne, additional, Beuret, Pascal, additional, Monchi, Mehran, additional, Delcourte, Claire, additional, Hayon, Jan, additional, Klouche, Kada, additional, Stoclin, Annabelle, additional, Gibot, Sébastien, additional, Peigne, Vincent, additional, Mezher, Chaouki, additional, Martino, Frédéric, additional, Nguyen, Maxime, additional, Kuteifan, Khaldoun, additional, Louis, Guillaume, additional, Rigault, Guillaume, additional, Masuccio, Michel, additional, Garin, Aude, additional, Asfar, Pierre, additional, Andrieu, Maude, additional, Auchabie, Johann, additional, Daviet, Florence, additional, Lacave, Guillaume, additional, Benhamida, Hotman, additional, Vivet, Bérengère, additional, Chaignat, Claire, additional, Desgrouas, Maxime, additional, La-Combe, Béatrice, additional, Plouvier, Fabienne, additional, Richard, Jean-Christophe, additional, Haddadi, Clément, additional, Czolnowski, Dorian, additional, Lau, Nicolas, additional, Jacobs, Frédéric, additional, Thirion, Marina, additional, Pons, Antoine, additional, Pichon, Nicolas, additional, Patrigeon, René-Gilles, additional, Vieillard-Baron, Antoine, additional, Uhel, Fabrice, additional, Rigaud, Jean-Philippe, additional, Bouhake, Yannis, additional, Zagozda, Dominique, additional, Arrestier, Romain, additional, Vinclair, Camille, additional, Fedou, Anne-Laure, additional, Dargent, Auguste, additional, Dellamonica, Jean, additional, Rey, Brice, additional, Gachet, Alexandre, additional, Serie, Mathieu, additional, Bruel, Cédric, additional, Troger, Antoine, additional, Berthoud, Vivien, additional, Delbove, Agathe, additional, Goulenok, Cyril, additional, Bouguoin, Wulfran, additional, Osman, David, additional, Anguel, Nadia, additional, Guerin, Laurent, additional, Foucault, Camille, additional, Preau, Sébastien, additional, Saura, Ouriel, additional, Boue, Yvonnick, additional, Sedillot, Nicholas, additional, Covin, Laetitia, additional, Lambiotte, Fabien, additional, Guignon, Carole, additional, Perinel-Ragey, Sophie, additional, Souloy, Xavier, additional, Defaux-Chevillard, Cécile, additional, Renault, Anne, additional, Mme-Ngapmen, Nadège, additional, Jourdain, Mercedes, additional, Van Der Linden, Thierry, additional, Levy, Clémentine, additional, Thouy, François, additional, and Degouy, Guillaume, additional

Published
2023
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15. Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study

Author

Saura, Ouriel, Rouzé, Anahita, Martin Loeches, Ignacio, Povoa, Pedro, Kreitmann, Louis, Torres Martí, Antoni, Metzelard, Matthieu, Du Cheyron, Damien, Lambiotte, Fabien, Tamion, Fabienne, Labruyere, Marie, Boulle Geronimi, Claire, Luyt, Charles-Edouard, Nyunga, Martine, Pouly, Olivier, Thille, Arnaud Wilfrid, Megarbane, Bruno, Saade, Anastasia, Magira, Eleni, Llitjos, Jean-François, Ioannidou, Iliana, Pierre, Alexandre, Reignier, Jean, Garot, Denis, Baudel, Jean-Luc, Voiriot, Guillaume, Plantefeve, Gaëtan, Morawiec, Elise, Asfar, Pierre, Boyer, Alexandre, Mekontso-Dessap, Armand, Bardaka, Fotini, Diaz, Emili, Vinsonneau, Christophe, Floch, Pierre-Edouard, Weiss, Nicolas, Ceccato, Adrian, Artigas, Antonio, Nora, David, Duhamel, Alain, Labreuche, Julien, Nseir, Saad, and coVAPid Study Group

Subjects
Adult, SARS-CoV-2, Respiradors, Incidence, Adrenocortical hormones, Pneumonia, Ventilator-Associated, COVID-19, Respiratory infections, Pneumònia, Pneumonia, Critical Care and Intensive Care Medicine, Corticosteroides, Infeccions respiratòries, Respiració artificial, Respiration, Artificial, Respirators, Intensive Care Units, Artificial respiration, Humans, Retrospective Studies
Abstract

Background Ventilator-associated pneumonia (VAP) is common in patients with severe SARS-CoV-2 pneumonia. The aim of this ancillary analysis of the coVAPid multicenter observational retrospective study is to assess the relationship between adjuvant corticosteroid use and the incidence of VAP. Methods Planned ancillary analysis of a multicenter retrospective European cohort in 36 ICUs. Adult patients receiving invasive mechanical ventilation for more than 48 h for SARS-CoV-2 pneumonia were consecutively included between February and May 2020. VAP diagnosis required strict definition with clinical, radiological and quantitative microbiological confirmation. We assessed the association of VAP with corticosteroid treatment using univariate and multivariate cause-specific Cox’s proportional hazard models with adjustment on pre-specified confounders. Results Among the 545 included patients, 191 (35%) received corticosteroids. The proportional hazard assumption for the effect of corticosteroids on the incidence of VAP could not be accepted, indicating that this effect varied during ICU stay. We found a non-significant lower risk of VAP for corticosteroid-treated patients during the first days in the ICU and an increased risk for longer ICU stay. By modeling the effect of corticosteroids with time-dependent coefficients, the association between corticosteroids and the incidence of VAP was not significant (overall effect p = 0.082), with time-dependent hazard ratios (95% confidence interval) of 0.47 (0.17–1.31) at day 2, 0.95 (0.63–1.42) at day 7, 1.48 (1.01–2.16) at day 14 and 1.94 (1.09–3.46) at day 21. Conclusions No significant association was found between adjuvant corticosteroid treatment and the incidence of VAP, although a time-varying effect of corticosteroids was identified along the 28-day follow-up.

Published
2023

16. Assessment of plasma endocan for the prediction of mortality in COVID-19 patients undergoing veno-venous ECMO: A pilot study

Author

Levy, C., primary, Dognon, N., additional, Normandin, S., additional, Duburcq, T., additional, Gaudet, A., additional, Parmentier-Decrucq, Erika, additional, Poissy, Julien, additional, Dubucquoi, Sylvain, additional, Boddaert, Pauline, additional, Caplan, Morgan, additional, Goutay, Julien, additional, Durand, Arthur, additional, Graffin, Benoit, additional, Gaudel, Myrtille, additional, Detollenaere, Charles, additional, Gueguen, Ines, additional, Ceunebroek, Marine Van, additional, Tortuyaux, Romain, additional, Saura, Ouriel, additional, Kalioubie, Ahmed El, additional, Favory, Raphael, additional, Girardie, Patrick, additional, Houard, Marion, additional, Jaillette, Emmanuelle, additional, Jourdain, Mercedes, additional, Ledoux, Geoffrey, additional, Mathieu, Daniel, additional, Moreau, Anne Sophie, additional, Nseir, Saad, additional, Onimus, Thierry, additional, Preau, Sebastien, additional, Robriquet, Laurent, additional, Rouze, Anahita, additional, Six, Sophie, additional, Soquet, Jerome, additional, Loobuyck, Valentin, additional, Mugnier, Agnes, additional, and Vincentelli, André, additional

Published
2023
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18. Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients

Author

Saura, Ouriel, Rouzé, Anahita, Martin-Loeches, Ignacio, Povoa, Pedro, Kreitmann, Louis, Torres, Antoni, Metzelard, Matthieu, Du Cheyron, Damien, Lambiotte, Fabien, Tamion, Fabienne, Labruyere, Marie, Boulle Geronimi, Claire, Luyt, Charles Edouard, Nyunga, Martine, Pouly, Olivier, Thille, Arnaud W., Megarbane, Bruno, Saade, Anastasia, Magira, Eleni, Llitjos, Jean François, Ioannidou, Iliana, Pierre, Alexandre, Reignier, Jean, Garot, Denis, Baudel, Jean Luc, Voiriot, Guillaume, Plantefeve, Gaëtan, Morawiec, Elise, Asfar, Pierre, Boyer, Alexandre, Mekontso-Dessap, Armand, Bardaka, Fotini, Diaz, Emili, Vinsonneau, Christophe, Floch, Pierre Edouard, Weiss, Nicolas, Ceccato, Adrian, Artigas, Antonio, Nora, David, Duhamel, Alain, Labreuche, Julien, Nseir, Saad, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Subjects
Ventilator-associated lower respiratory tract infections, SARS-CoV-2, Corticosteroids, COVID-19, Critical Care and Intensive Care Medicine
Abstract

Funding This study was supported in part by a grant from the French government through the « Programme Investissement d’Avenir» (I-SITE ULNE) managed by the Agence Nationale de la Recherche (coVAPid project). Prof. Ignacio Martin-Loeches has been supported by SFI (Science Foundation Ireland), Grant number 20/COV/0038. The funders of the study had no role in the study design, data collection, analysis or interpretation, writing of the report or deci sion to submit for publication. BACKGROUND: Ventilator-associated pneumonia (VAP) is common in patients with severe SARS-CoV-2 pneumonia. The aim of this ancillary analysis of the coVAPid multicenter observational retrospective study is to assess the relationship between adjuvant corticosteroid use and the incidence of VAP. METHODS: Planned ancillary analysis of a multicenter retrospective European cohort in 36 ICUs. Adult patients receiving invasive mechanical ventilation for more than 48 h for SARS-CoV-2 pneumonia were consecutively included between February and May 2020. VAP diagnosis required strict definition with clinical, radiological and quantitative microbiological confirmation. We assessed the association of VAP with corticosteroid treatment using univariate and multivariate cause-specific Cox's proportional hazard models with adjustment on pre-specified confounders. RESULTS: Among the 545 included patients, 191 (35%) received corticosteroids. The proportional hazard assumption for the effect of corticosteroids on the incidence of VAP could not be accepted, indicating that this effect varied during ICU stay. We found a non-significant lower risk of VAP for corticosteroid-treated patients during the first days in the ICU and an increased risk for longer ICU stay. By modeling the effect of corticosteroids with time-dependent coefficients, the association between corticosteroids and the incidence of VAP was not significant (overall effect p = 0.082), with time-dependent hazard ratios (95% confidence interval) of 0.47 (0.17-1.31) at day 2, 0.95 (0.63-1.42) at day 7, 1.48 (1.01-2.16) at day 14 and 1.94 (1.09-3.46) at day 21. CONCLUSIONS: No significant association was found between adjuvant corticosteroid treatment and the incidence of VAP, although a time-varying effect of corticosteroids was identified along the 28-day follow-up. publishersversion published

Published
2022

20. Relationship between corticosteroid administration and incidence of ventilator-associated lower respiratory tract infections in COVID-19 patients: a retrospective multicenter study

Author

SAURA, Ouriel, primary, ROUZE, Anahita, additional, MARTIN-LOECHES, Ignacio, additional, POVOA, Pedro, additional, KREITMANN, Louis, additional, TORRES, Antoni, additional, METZELARD, Matthieu, additional, DU CHEYRON, Damien, additional, LAMBIOTTE, Fabien, additional, TAMION, Fabienne, additional, LABRUYERE, Marie, additional, GERONIMI, Claire BOULLE, additional, LUYT, Charles-Edouard, additional, NYUNGA, Martine, additional, POULY, Olivier, additional, THILLE, Arnaud W., additional, MEGARBANE, Bruno, additional, SAADE, Anastasia, additional, MAGIRA, Eleni, additional, LLITJOS, Jean-François, additional, IOANNIDOU, Iliana, additional, PIERRE, Alexandre, additional, REIGNIER, Jean, additional, GAROT, Denis, additional, BAUDEL, Jean-Luc, additional, VOIRIOT, Guillaume, additional, PLANTEFEVE, Gaëtan, additional, MORAWIEC, Elise, additional, ASFAR, Pierre, additional, BOYER, Alexandre, additional, MEKONTSO-DESSAP, Armand, additional, BARDAKA, Fotini, additional, DIAZ, Emilio, additional, VINSONNEAU, Christophe, additional, FLOCH, Pierre-Edouard, additional, WEISS, Nicolas, additional, CECCATO, Adrian, additional, ARTIGAS, Antonio, additional, NORA, David, additional, DUHAMEL, Alain, additional, LABREUCHE, Julien, additional, and NSEIR, Saad, additional

Published
2022
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21. Additional file 2 of Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

Author

Aissi James, Sarah, Guervilly, Christophe, Lesouhaitier, Mathieu, Coppens, Alexandre, Haddadi, Clément, Lebreton, Guillaume, Nizard, Jacky, Brechot, Nicolas, Assouline, Benjamin, Saura, Ouriel, Levy, David, Lefèvre, Lucie, Barhoum, Pétra, Chommeloux, Juliette, Hékimian, Guillaume, Luyt, Charles-Edouard, Kimmoun, Antoine, Combes, Alain, and Schmidt, Matthieu

Abstract

Additional file 2 Comparison of health-related quality of life assessed by mean SF-36 scores in ECMO-rescued ARDS survivors according to the timing of delivery. ECMO, extracorporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; IES, impact of event scales; PTSD, post-traumatic stress disorder.

Published
2022
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22. Additional file 1 of Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study

Author

Saura, Ouriel, Rouzé, Anahita, Martin-Loeches, Ignacio, Povoa, Pedro, Kreitmann, Louis, Torres, Antoni, Metzelard, Matthieu, Du Cheyron, Damien, Lambiotte, Fabien, Tamion, Fabienne, Labruyere, Marie, Boulle Geronimi, Claire, Luyt, Charles-Edouard, Nyunga, Martine, Pouly, Olivier, Thille, Arnaud W., Megarbane, Bruno, Saade, Anastasia, Magira, Eleni, Llitjos, Jean-François, Ioannidou, Iliana, Pierre, Alexandre, Reignier, Jean, Garot, Denis, Baudel, Jean-Luc, Voiriot, Guillaume, Plantefeve, Gaëtan, Morawiec, Elise, Asfar, Pierre, Boyer, Alexandre, Mekontso-Dessap, Armand, Bardaka, Fotini, Diaz, Emili, Vinsonneau, Christophe, Floch, Pierre-Edouard, Weiss, Nicolas, Ceccato, Adrian, Artigas, Antonio, Nora, David, Duhamel, Alain, Labreuche, Julien, and Nseir, Saad

Abstract

Additional file 1. Supplementary e-figures and e-tables.

Published
2022
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24. IMPELLA® or Extracorporeal Membrane Oxygenation for Left Ventricular Dominant Refractory Cardiogenic Shock

Author

Schurtz, Guillaume, primary, Rousse, Natacha, additional, Saura, Ouriel, additional, Balmette, Vincent, additional, Vincent, Flavien, additional, Lamblin, Nicolas, additional, Porouchani, Sina, additional, Verdier, Basile, additional, Puymirat, Etienne, additional, Robin, Emmanuel, additional, Van Belle, Eric, additional, Vincentelli, André, additional, Aissaoui, Nadia, additional, Delhaye, Cédric, additional, Delmas, Clément, additional, Cosenza, Alessandro, additional, Bonello, Laurent, additional, Juthier, Francis, additional, Moussa, Mouhamed Djahoum, additional, and Lemesle, Gilles, additional

Published
2021
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25. Assessment of plasma endocan for the prediction of mortality in COVID-19 patients undergoing veno-venous ECMO: A pilot study

Author

Parmentier-Decrucq, Erika, Poissy, Julien, Dubucquoi, Sylvain, Boddaert, Pauline, Caplan, Morgan, Goutay, Julien, Durand, Arthur, Graffin, Benoit, Gaudel, Myrtille, Detollenaere, Charles, Gueguen, Ines, Ceunebroek, Marine Van, Tortuyaux, Romain, Saura, Ouriel, Kalioubie, Ahmed El, Favory, Raphael, Girardie, Patrick, Houard, Marion, Jaillette, Emmanuelle, Jourdain, Mercedes, Ledoux, Geoffrey, Mathieu, Daniel, Moreau, Anne Sophie, Nseir, Saad, Onimus, Thierry, Preau, Sebastien, Robriquet, Laurent, Rouze, Anahita, Six, Sophie, Soquet, Jerome, Loobuyck, Valentin, Mugnier, Agnes, Vincentelli, André, Levy, C., Dognon, N., Normandin, S., Duburcq, T., and Gaudet, A.

Published
2023
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26. IMPELLA ® or Extracorporeal Membrane Oxygenation for Left Ventricular Dominant Refractory Cardiogenic Shock.

Author

Schurtz, Guillaume, Rousse, Natacha, Saura, Ouriel, Balmette, Vincent, Vincent, Flavien, Lamblin, Nicolas, Porouchani, Sina, Verdier, Basile, Puymirat, Etienne, Robin, Emmanuel, Van Belle, Eric, Vincentelli, André, Aissaoui, Nadia, Delhaye, Cédric, Delmas, Clément, Cosenza, Alessandro, Bonello, Laurent, Juthier, Francis, Moussa, Mouhamed Djahoum, and Lemesle, Gilles

Subjects
EXTRACORPOREAL membrane oxygenation, CARDIOGENIC shock
Abstract

Mechanical circulatory support (MCS) devices are effective tools in managing refractory cardiogenic shock (CS). Data comparing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and IMPELLA® are however scarce. We aimed to assess outcomes of patients implanted with these two devices and eligible to both systems. From 2004 to 2020, we retrospectively analyzed 128 patients who underwent VA-ECMO or IMPELLA® in our institution for refractory left ventricle (LV) dominant CS. All patients were eligible to both systems: 97 patients were first implanted with VA-ECMO and 31 with IMPELLA®. The primary endpoint was 30-day all-cause death. VA-ECMO patients were younger (52 vs. 59.4, p = 0.006) and had a higher lactate level at baseline than those in the IMPELLA® group (6.84 vs. 3.03 mmol/L, p < 0.001). Duration of MCS was similar between groups (9.4 days vs. 6 days in the VA-ECMO and IMPELLA® groups respectively, p = 0.077). In unadjusted analysis, no significant difference was observed between groups in 30-day mortality: 43.3% vs. 58.1% in the VA-ECMO and IMPELLA® groups, respectively (p = 0.152). After adjustment, VA-ECMO was associated with a significant reduction in 30-day mortality (HR = 0.25, p = 0.004). A higher rate of MCS escalation was observed in the IMPELLA® group: 32.3% vs. 10.3% (p = 0.003). In patients eligible to either VA-ECMO or IMPELLA® for LV dominant refractory CS, VA-ECMO was associated with improved survival rate and a lower need for escalation. [ABSTRACT FROM AUTHOR]

Published
2021
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