14,606 results on '"Savitri, A"'
Search Results
2. Imaging and Spectral Fitting of Bright Gamma-ray Sources with the COSI Balloon Payload
- Author
-
Roberts, Jarred M., Boggs, Steven, Siegert, Thomas, Tomsick, John A., Ajello, Marco, von Ballmoos, Peter, Beechert, Jacqueline, Cangemi, Floriane, Gallego, Savitri, Jean, Pierre, Karwin, Chris, Kierans, Carolyn, Lazar, Hadar, Lowell, Alex, Castellanos, Israel Martinez, Pike, Sean, Sleator, Clio, Sheng, Yong, Yoneda, Hiroki, and Zoglauer, Andreas
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
The Compton Spectrometer and Imager balloon payload (COSI-Balloon) is a wide-field-of-view Compton ${\gamma}$-ray telescope that operates in the 0.2 - 5 MeV bandpass. COSI-Balloon had a successful 46-day flight in 2016 during which the instrument observed the Crab Nebula, Cygnus X-1, and Centaurus A. Using the data collected by the COSI-Balloon instrument during this flight, we present the source flux extraction of signals from the variable balloon background environment and produce images of these background-dominated sources by performing Richardson-Lucy deconvolutions. We also present the spectra measured by the COSI-Balloon instrument, compare and combine them with measurements from other instruments, and fit the data. The Crab Nebula was observed by COSI-Balloon and we obtain a measured flux in the energy band 325 - 480 keV of (4.5 ${\pm}$ 1.6) ${\times}$ 10$^{-3}$ ph cm$^{-2}$ s$^{-1}$. The model that best fits the COSI-Balloon data combined with measurements from NuSTAR and Swift-BAT is a broken power law with a measured photon index ${\Gamma}$ = 2.20 ${\pm}$ 0.02 above the 43 keV break. Cygnus X-1 was also observed during this flight, and we obtain a measured flux of (1.4 ${\pm}$ 0.2) ${\times}$ 10$^{-3}$ ph cm$^{-2}$ s$^{-1}$ in the same energy band and a best-fit result (including data from NuSTAR, Swift-BAT, and INTEGRAL/ IBIS) was to a cutoff power law with a high-energy cutoff energy of 138.3 ${\pm}$ 1.0 keV and a photon index of ${\Gamma}$ = 1.358 ${\pm}$ 0.002. Lastly, we present the measured spectrum of Centaurus A and our best model fit to a power law with a photon index of ${\Gamma}$ = 1.73 ${\pm}$ 0.01.
- Published
- 2024
- Full Text
- View/download PDF
3. Comparing Labor Market Performance of Vocational and General School Graduates in Indonesia: Insights from Stable and Crisis Conditions
- Author
-
Kasmad Ariansyah, Yanuar Farida Wismayanti, Renny Savitri, Virgiawan Listanto, Azwar Aswin, Madya Putra Yaumil Ahad, and Benedicta Retna Cahyarini
- Abstract
This study seeks to investigate the association between distinct tracks of secondary education--namely, vocational school (Sekolah Menengah Kejuruan, SMK) and general school (Sekolah Menengah Atas, SMA)--and two key labor market outcomes: the duration required for graduates to attain their initial employment and their resilience in the face of pandemic, as measured by changes in average monthly income. While the former sheds light on the outcome under typical circumstances, the latter offers valuable insights into the outcome during periods of crisis. Focused on Indonesia, this research employs Heckman two-step model alongside ordinary least square (OLS) for the first outcome and ordered probit regression for the second. The research draws upon data extracted from the 2021 National Labor Force Survey (Survey Angkatan Kerja Nasional, SAKERNAS). Our results suggest that SMK provides an advantage in securing initial employment compared to SMA, with SMK graduates entering the workforce earlier than their counterparts. Moreover, in terms of resilience during the pandemic, as evidenced by changes in income, SMK graduates exhibit greater resilience, with a higher likelihood of maintaining or even increasing their income compared to SMA graduates. These findings offer valuable implications for both theoretical understanding and practical considerations.
- Published
- 2024
- Full Text
- View/download PDF
4. Atmospheric Response for MeV Gamma Rays Observed with Balloon-Borne Detectors
- Author
-
Karwin, Chris, Kierans, Carolyn, Shih, Albert, Castellanos, Israel Martinez, Lowell, Alex, Siegert, Thomas, Roberts, Jarred, Gallego, Savitri, Laviron, Adrien, Zoglauer, Andreas, Tomsick, John, and Boggs, Steven
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The atmospheric response for MeV gamma rays (~ 0.1 - 10 MeV) can be characterized in terms of two observed components. The first component is due to photons that reach the detector without scattering. The second component is due to photons that reach the detector after scattering one or more times. While the former can be determined in a straightforward manner, the latter is much more complex to quantify, as it requires tracking the transport of all source photons that are incident on Earth's atmosphere. The scattered component can cause a significant energy-dependent distortion in the measured spectrum, which is important to account for when making balloon-borne observations. In this work we simulate the full response for gamma-ray transport in the atmosphere. We find that the scattered component becomes increasingly more significant towards lower energies, and at 0.1 MeV it may increase the measured flux by as much as a factor of ~2-4, depending on the photon index and off-axis angle of the source. This is particularly important for diffuse sources, whereas the effect from scattering can be significantly reduced for point sources observed with an imaging telescope., Comment: 24 pages, 18 figures. Accepted to The Astrophysical Journal
- Published
- 2024
5. Saccharification of carrot pomace and use as nutrient source for the production of ꞵ-cryptoxanthin by Pantoea anthophila FL1_IS5
- Author
-
Korkerd, Sopida, Vatanyoopaisarn, Savitri, Visessanguan, Wonnop, Thumthanarak, Benjawan, Perez, Caroline L., Rungsardthong, Vilai, and Mussatto, Solange I.
- Published
- 2024
- Full Text
- View/download PDF
6. Analysis of Language Errors in High School Students’ Speech Text
- Author
-
Yuanita, Arie, Sudikan, Setya Y., Mulyono, Savitri, Agusniar D., Striełkowski, Wadim, Editor-in-Chief, Black, Jessica M., Series Editor, Butterfield, Stephen A., Series Editor, Chang, Chi-Cheng, Series Editor, Cheng, Jiuqing, Series Editor, Dumanig, Francisco Perlas, Series Editor, Al-Mabuk, Radhi, Series Editor, Scheper-Hughes, Nancy, Series Editor, Urban, Mathias, Series Editor, Webb, Stephen, Series Editor, Putri, Cicilia D. M., editor, Mustofa, Ali, editor, Hakim, Wendy, editor, Pradana, Galih, editor, and Tandyonomanu, Danang, editor
- Published
- 2025
- Full Text
- View/download PDF
7. Recommendations for Performance Evaluation of Machine Learning in Pathology. A Concept Paper From the College of American Pathologists
- Author
-
HannaMD, Matthew G., Olson, Niels H., Zarella, Mark, Dash, Rajesh C., Herrmann, Markus D., Furtado, Larissa V., Stram, Michelle N., Raciti, Patricia M., Hassell, Lewis, Mays, Alex, Pantanowitz, Liron, Sirintrapun, Joseph S., Krishnamurthy, Savitri, Parwani, Anil, Lujan, Giovanni, Evans, Andrew, Glassy, Eric F., Bui, Marilyn M., Singh, Rajendra, Souers, Rhona J., Baca, Monica E. de, and Seheult, Jansen N.
- Subjects
Technology application ,Usage ,Machine learning -- Usage ,Clinical pathology -- Technology application - Abstract
Institution of machine learning (ML) in the pathology clinical domain has gained momentum and is rapidly advancing. As ML-based clinical decision support (CDS) systems continue to mature, laboratories will increasingly [...], * Context.-Machine learning applications in the pathology clinical domain are emerging rapidly. As decision support systems continue to mature, laboratories will increasingly need guidance to evaluate their performance in clinical practice. Currently there are no formal guidelines to assist pathology laboratories in verification and/or validation of such systems. These recommendations are being proposed for the evaluation of machine learning systems in the clinical practice of pathology. Objective.-To propose recommendations for performance evaluation of in vitro diagnostic tests on patient samples that incorporate machine learning as part of the pre-analytical, analytical, or post-analytical phases of the laboratory workflow. Topics described include considerations for machine learning model evaluation including risk assessment, predeployment requirements, data sourcing and curation, verification and validation, change control management, human-computer interaction, practitioner training, and competency evaluation. Data Sources.-An expert panel performed a review of the literature, Clinical and Laboratory Standards Institute guidance, and laboratory and government regulatory frameworks. Conclusions.-Review of the literature and existing documents enabled the development of proposed recommendations. This white paper pertains to performance evaluation of machine learning systems intended to be implemented for clinical patient testing. Further studies with real-world clinical data are encouraged to support these proposed recommendations. Performance evaluation of machine learning models is critical to verification and/or validation of in vitro diagnostic tests using machine learning intended for clinical practice. (Arch Pathol Lab Med. 2024;148:e335-e361; doi: 10.5858/arpa.2023-0042-CP)
- Published
- 2024
- Full Text
- View/download PDF
8. Quantification of Interference Constraint for Small Cells in Low SINR Regime With Steepest Ascent Method.
- Author
-
Sanjeeb Shrestha, Xiaojing Huang 0001, Kashif Saleem, Savitri Bevinakoppa, and Tony Jan
- Published
- 2025
- Full Text
- View/download PDF
9. Physicochemical Properties of Spray-Dried Microcapsules Prepared with Gamma Oryzanol Pre-encapsulated in Zein Nanoparticles and Maltodextrin as a Drying Agent
- Author
-
Rodsuwan, Ubonphan, Vatanyoopaisarn, Savitri, Thumthanaruk, Benjawan, Thisayakorn, Krittiya, Uttapap, Dudsadee, Zhong, Qixin, and Rungsardthong, Vilai
- Published
- 2024
- Full Text
- View/download PDF
10. The Role of Subcutaneous Furosemide in Heart Failure Management: A Systematic Review
- Author
-
Widiarti, Wynne, Saputra, Pandit Bagus Tri, Ariyanto, Melissa Valentina, Savitri, Cornelia Ghea, Multazam, Chaq El Chaq Zamzam, Putranto, Johanes Nugroho Eko, and Alkaff, Firas Farisi
- Published
- 2024
- Full Text
- View/download PDF
11. Microencapsulation of gamma oryzanol using inulin as wall material by spray drying: optimization of formulation and characterization of microcapsules
- Author
-
Rodsuwan, Ubonphan, Thumthanaruk, Benjawan, Vatanyoopaisarn, Savitri, Thisayakorn, Krittiya, Zhong, Qixin, Panjawattanangkul, Somjate, and Rungsardthong, Vilai
- Published
- 2024
- Full Text
- View/download PDF
12. NGS-Based Metagenomics Depicting Taxonomic and Functional Insights into North-Western Himalayan Hot Springs
- Author
-
Rangra, Shailja, Sharma, Nitish, Lata, Prem, Sharma, Kiran Bala, Kumari, Reena, Singh, Sudhir P., and Savitri
- Published
- 2024
- Full Text
- View/download PDF
13. NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy via c-JUN repression
- Author
-
Reddy, Tejaswini, Puri, Akshjot, Guzman-Rojas, Liliana, Thomas, Christoforos, Qian, Wei, Zhou, Jianying, Zhao, Hong, Mahboubi, Bijan, Oo, Adrian, Cho, Young-Jae, Kim, Baek, Thaiparambil, Jose, Rosato, Roberto, Martinez, Karina Ortega, Chervo, Maria Florencia, Ayerbe, Camila, Giese, Noah, Wink, David, Lockett, Stephen, Wong, Stephen, Chang, Jeffrey, Krishnamurthy, Savitri, Yam, Clinton, Moulder, Stacy, Piwnica-Worms, Helen, Meric-Bernstam, Funda, and Chang, Jenny
- Published
- 2024
- Full Text
- View/download PDF
14. Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer
- Author
-
Wang, Xiaoping, Zhao, Li, Song, Xingzhi, Wu, Xiaogang, Krishnamurthy, Savitri, Semba, Takashi, Shao, Shan, Knafl, Mark, Coffer, II, Larry W., Alexander, Angela, Vines, Anita, Bopparaju, Swetha, Woodward, Wendy A., Chu, Randy, Zhang, Jianhua, Yam, Clinton, Loo, Lenora W. M., Nasrazadani, Azadeh, Huong, Le-Petross, Woodman, Scott E., Futreal, Andrew, Tripathy, Debu, and Ueno, Naoto T.
- Published
- 2024
- Full Text
- View/download PDF
15. Correction: Biogenically synthesized green silver nanoparticles exhibit antimalarial activity
- Author
-
Tiwari, Savitri, Kumar, Reetesh, Devi, Sonia, Sharma, Prakriti, Chaudhary, Neil Roy, Negi, Sushmita, Tandel, Nikunj, Marepally, Srujan, Pied, Sylviane, and Tyagi, Rajeev K.
- Published
- 2024
- Full Text
- View/download PDF
16. Biogenically synthesized green silver nanoparticles exhibit antimalarial activity
- Author
-
Tiwari, Savitri, Kumar, Reetesh, Devi, Sonia, Sharma, Prakriti, Chaudhary, Neil Roy, Negi, Sushmita, Tandel, Nikunj, Marepally, Srujan, Pied, Sylviane, and Tyagi, Rajeev K.
- Published
- 2024
- Full Text
- View/download PDF
17. PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
- Author
-
Acharya, Sundaram, Ansari, Asgar Hussain, Kumar Das, Prosad, Hirano, Seiichi, Aich, Meghali, Rauthan, Riya, Mahato, Sudipta, Maddileti, Savitri, Sarkar, Sajal, Kumar, Manoj, Phutela, Rhythm, Gulati, Sneha, Rahman, Abdul, Goel, Arushi, Afzal, C., Paul, Deepanjan, Agrawal, Trupti, Pulimamidi, Vinay Kumar, Jalali, Subhadra, Nishimasu, Hiroshi, Mariappan, Indumathi, Nureki, Osamu, Maiti, Souvik, and Chakraborty, Debojyoti
- Published
- 2024
- Full Text
- View/download PDF
18. Effectiveness of Edutainment Module Based on Local Excellence of Pantai Utara Indonesia Reviewed from Students' Concept Understanding
- Author
-
Wanabuliandari, Savitri and Ardianti, Sekar Dwi
- Abstract
The purpose of this study was to analyze edutainment modules based on local excellence in Pantai Utara of Indonesia in terms of students' conceptual comprehension abilities. The edutainment module based on local excellence on Pantai Utara of Indonesia was developed with the Borg and Gall models developed. The development phase of the ethno-edutain module adds preliminary studios, product development and validation, and product trial trials. In testing the product, a large-scale trial was conducted. The effectiveness test was carried out on a large-scale trial with research subjects of fourth grade students at SD IT Umar Bin Khattab. The effectiveness of the ethno-edutainment module was accepted using test techniques. Based on N-gain trials Increased pretest and posttest scores of students produced 8 students increased in the high category, 21 students increased in the moderate category, and 3 students increased in the low category.
- Published
- 2023
19. Parent-Adolescent Conflicts Viewed from Emotional Independence and Parenting Styles
- Author
-
Vision Vision, Jane Savitri, and Jacqueline Tjandraningtyas
- Subjects
parent-adolescent conflicts, emotional autonomy, parenting styles, adolescents ,Psychology ,BF1-990 - Abstract
The level of parent-adolescent conflicts increases after children attain puberty, facilitated by hormonal changes and cognitive development, which are believed to contribute to adolescents developing a sense of emotional autonomy from parents. These changes often lead to parent-adolescent conflicts, facilitating more mature and equal relationships between both parties. Parenting styles in responding to adolescents’ growing need for independence also influence the conflicts. Therefore, this study aimed to investigate the impact of adolescents’ emotional autonomy and parenting styles on the level of conflicts. To achieve this objective, a quantitative study was conducted on 386 Junior and Senior High School students from X Foundation, Denpasar. The results of multiple regression analysis showed that both emotional autonomy and parenting styles significantly impacted parent-adolescent conflicts. The contribution of these variables was more pronounced for mothers (50%) than fathers (43%). Both authoritative and authoritarian parenting styles were found to influence conflicts. Therefore, reducing parent-adolescent conflicts required considering adolescents’ emotional autonomy and fostering authoritative parenting styles.
- Published
- 2024
- Full Text
- View/download PDF
20. Karakteristik Pemeliharaan Kuda Andong di Pantai Parangtritis dan Malioboro
- Author
-
Mohammad Rakha Surya Pranaja, Yashinta Amperawati, Aliyya Nur Faiza, Nabila Shafa Nur Aliyyah, Asyam Hafidz Wenni, Azalea Perwita Savitri, Nabila Febriyana Najwa, Nur Lailya Agatha, Syifa Annisa, and Vista Budiariati
- Subjects
kuda andong ,manajemen pemeliharaan ,mcmaster ,sentrifus ,Veterinary medicine ,SF600-1100 - Abstract
Kuda andong merupakan salah satu ikon khas Yogyakarta dan memiliki peran besar dalam menarik perhatian wisatawan. Beberapa tempat wisata di Yogyakarta yang menyediakan kuda andong adalah Pantai Parangtritis dan Malioboro. Performa kuda, khususnya pada kuda pekerja dipengaruhi oleh beberapa manajemen pemeliharaan yang saling berkaitan. Manajemen pemeliharaan yang buruk dapat mengakibatkan kuda mudah terinfeksi suatu penyakit, malnutrisi, dan produktivitas rendah. Tujuan dari penelitian ini untuk mengetahui karakteristik pemeliharaan kuda andong di Pantai Parangtritis dan Malioboro guna mengidentifikasi masalah pemeliharaan kuda andong yang ada pada wilayah tersebut beserta solusinya. Pengumpulan data dilakukan dengan pengisian kuesioner oleh 51 kusir andong di Pantai Parangtritis dan Malioboro. Kuesioner terdiri dari 27 pertanyaan terkait manajemen pemeliharaan kuda andong. Selain itu, juga dilakukan pengambilan sampel feses kuda andong untuk pemeriksaan dengan metode sentrifus dan McMaster.
- Published
- 2024
- Full Text
- View/download PDF
21. Stability and Kinetic Study of Vitamin C containing Hydrogenated and Middle-Chain Triglyceride Coconut Oil-Based Double Emulsion
- Author
-
Lanny Sapei, Emma Savitri, Ignasius Radix A.P. Jati, Rochmad Indrawanto, Hillary Emmanuella Darsono, Yenni Anggraeni, and Cindy Sumampouw
- Subjects
double emulsion ,hcno ,kinetics ,tween-20 ,vitamin c ,Technology ,Technology (General) ,T1-995 - Abstract
Vitamin C or ascorbic acid, is an organic compound that is highly required by human since it acts as antioxidant, help increase metabolism, and improves the immune system. Vitamin C is easily oxidized and damaged during storage due to several external factors such as light, metal, shear, etc. The encapsulation technique is able to improve the stability as well as the activity of Vitamin C in order to protect the bioactive compound from deleterious external factors. Coconut oil which is composed of about 50% lauric acid, has an antiviral property. This research aimed to obtain the stable water-in-oil-in-water (W1/O/W2) double emulsion using coconut oil upon the incorporation of Vitamin C. Hydrogenated (HCNO) and Medium-Chain Triglycerides (MCT) coconut oil was used as the oil phase, and various emulsifiers such as Tween-20 0.5%, Tween-20 1%, and Tween-20 0.5%/ PgPr 0.5% were applied to strengthen the outer interfacial layer. The double emulsion stability was monitored macroscopically, and the destabilization kinetics was studied using the zero and first-order kinetic models. It turned out that the HCNO-based double emulsion demonstrated higher stability compared to the MCT-based double emulsion. The lowest destabilization rate constants of 4.5 x 10-3 h-1 and 6.8 x 10-3 h-1 were obtained for HCNO and MCT-based double emulsions both stabilized with Tween-20 0.5%, respectively. The coconut oil-based double emulsion enriched with Vitamin C would be potentially developed for various functional food applications.
- Published
- 2024
- Full Text
- View/download PDF
22. Quality Analysis of Natural Processed Coffee Using Different Roasting Levels
- Author
-
Mulia Dwi Nur Apriliyani, Dyah Ayu Savitri, Hasbi Mubarak Suud, and Distiana Wulanjari
- Subjects
Agriculture ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Coffee is one of the leading plantation commodities in Indonesia. High-quality coffee has a higher price than low-quality coffee. The quality of coffee is determined by the method of selecting planting materials, handling during harvest, and processing. Coffee that is processed naturally, will be dried in the form of fruit/cherry so that coffee will decrease in quality. The quality of coffee beans can be improved if the roasting process is carried out using the right roasting temperature and time. With a variety of treatments in post-harvest processing methods and roasting levels will produce different coffee quality so that appropriate treatment is needed to determine the final result of coffee with the best quality. This study used the Complete Randomized Design (CRD) method with 2 factors, namely differences in coffee types (robusta coffee and arabica coffee) and roasting levels (light roast, medium roast, and dark roast). The research variables observed were seed weight, camba density, water content, and caffeine content. The data obtained will be analyzed using analysis of variance. If there is a significant difference between treatments, then further tests will be carried out using the Duncan Multiple Range Test (DMRT) at the 5% failure level.
- Published
- 2024
- Full Text
- View/download PDF
23. Identification of Kinship and Characterization of Yellow Bean Local Robusta Coffee
- Author
-
Gatot Subroto, Sholeh Avivi, Dwi Erwin Kusbianto, Hasbi Mubarak Suud, and Dyah Ayu Savitri
- Subjects
Agriculture ,Nutrition. Foods and food supply ,TX341-641 - Abstract
— Curahpoh Village, Bondowoso Regency, has the potential to become a center for producing Robusta coffee. The uniqueness is found in several Robusta coffee outliers which produce yellow fruit resembling yellow cattura and yellow bourbon which are only found in Arabica species. A new clone of “yellow robusta coffee” found in Curahpoh Village needs to be characterized and identified for its kinship with existing robusta coffees on the market. It is hoped that the results of this study will become the basis for claims for the first superior new yellow coffee clone in Robusta coffee. This study used several morphological, physiological parameters to characterize these superior clones and identification of kinship with several other Robusta clones using RAPD (Random Amplified Polymorphic DNA). Other robusta clones as a comparison were imported from several community plantations or state-owned enterprises in Bondowoso district and its surroundings. The interim results in this study were that Robusta coffee in Curahpoh village was morphologically identical to BP 44, BP 42, BP 534 and BP358. This hypothesis is supported by the appearance of the leaves which are known to have waves that are quite strong compared to other coffee varieties collected in the trial greenhouse. Morphologically, Robusta coffee in Curahpoh village has similarities/identical with BP 44, BP 42, BP 534 and BP358 on the parameters of leaf number, leaf shape, leaf morphology and fruit color on the plant. Clones BP409, BP42, Sinasense, BP358, BP939, and Propelegitu are coffee clones that are molecularly highly related.
- Published
- 2024
- Full Text
- View/download PDF
24. Relationship between Serum Ferritin Levels and Sarcopenia in Transfusion-Dependent Thalassemia Patient
- Author
-
Rendra Prasetya Saefudin, Siprianus Ugroseno Yudho Bintoro, Sony Wibisono Mudjanarko, Merlyna Savitri, Lukita Pradhevi, Agustinus Vincent, Michael Austin Pradipta Lusida, and Kartika Afrida Fauzia
- Subjects
ferritin serum ,human and disease ,iron overload ,sarcopenia ,thalassemia ,Public aspects of medicine ,RA1-1270 ,Biotechnology ,TP248.13-248.65 - Abstract
Introduction: Transfusion-dependent thalassemia (TDT) patients require regular blood transfusions for survival. One of the complications of repeated blood transfusions is iron overload, which occurs when iron accumulates in various organs and causes clinical complications. Recent studies have mentioned a correlation between increased ferritin and decreased skeletal muscle mass, but until now, no study has been conducted in thalassemia patients. We aim to evaluate the relationship between ferritin levels and sarcopenia in TDT patients. Methods: We included 81 TDT patients aged 18–65 years old at Dr. Soetomo Academic General Hospital, Surabaya, Indonesia, from April 1, 2024, to June 30, 2024. This was a single-center study and cross-sectional in design. Patients with a Karnofsky score ≤90, who had liver cirrhosis and a history of alcoholism, malignancy, acute infection, HIV, tuberculosis, hepatitis B, hepatitis C, diabetes mellitus, chronic kidney disease, obesity, and stroke were excluded. Results: Forty-five patients (55.6%) were sarcopenia and 36 patients (44.4%) were not sarcopenia. Age (P = 0.236), duration of thalassemia (P = 0.057), frequency of transfusion (P < 0.001), type of iron chelation (P < 0.001), and smoking habits (P = 0.029) had a significant association with ferritin serum levels. Protein diet (P = 0.03) and daily physical activity (P = 0.001) are significantly associated with sarcopenia. There was a significant difference between serum ferritin levels in the sarcopenia and nonsarcopenia groups (P < 0.001). Conclusions: Higher serum ferritin levels will increase the incidence of sarcopenia in TDT patients (adjusted odds ratio 1.001 [1.000–1.001]). A decrease in physical activity will increase the incidence of sarcopenia in TDT patients (P < 0.001).
- Published
- 2024
- Full Text
- View/download PDF
25. Deep Vein Thrombosis as a Complication of Gemcitabine-Capecitabine Chemotherapy in Adenocarcinoma of Gallbladder
- Author
-
Widiasi ED, Romadhon PZ, Ashariati A, Bintoro SUY, Diansyah MN, Amrita PNA, and Savitri M
- Subjects
gallbladder cancer ,deep vein thrombosis ,cancer-associated thrombosis ,khorana-vienna cat score ,chemotherapy ,thromboprophylaxis ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Abstract
Etha Dini Widiasi,1 Pradana Zaky Romadhon,1– 3 Ami Ashariati,1,3 Siprianus Ugroseno Yudho Bintoro,1,3 Muhammad Noor Diansyah,1– 3 Putu Niken Ayu Amrita,1,3 Merlyna Savitri1,3 1Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; 2Department of Internal Medicine, Universitas Airlangga Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; 3Division of Hematology and Medical Oncology, Department of Internal Medicine, Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaCorrespondence: Pradana Zaky Romadhon, Department of Internal Medicine, Universitas Airlangga Hospital, Faculty of Medicine, Universitas Airlangga, Jalan Dharmahusada Permai, Mulyorejo, Surabaya, Jawa Timur, Indonesia, 60115, Email zaky.romadhon@fk.unair.ac.idAbstract: Gallbladder adenocarcinoma has a high mortality rate, with approximately 1.7% cancer-related deaths worldwide. Cancer-associated thrombosis (CAT), including deep vein thrombosis (DVT), can significantly increase the risk of mortality within cancer patients, especially in pancreatic, brain, and intra-abdominal cancers, as well as in advanced and metastatic cancers. In this case report, there was a 45-year-old male patient diagnosed with advanced gallbladder adenocarcinoma UICC stage IVB with a TNM stage of T2b, N0, M1 with liver metastases who experienced pain and swelling in both lower limbs after undergoing a VI-A cycle of chemotherapy with gemcitabine capecitabine. The risk of thrombosis was calculated using the modified Khorana-Vienna CAT scores, which increased during every chemotherapy session. In this case, the Khorana-Vienna CAT score was calculated during two latest cycle of chemotherapy that somewhat considered delayed as the patient had already shown hypercoagulopathy symptoms and developed a poorer prognosis. Early CAT scoring, ideally before starting chemotherapy session, potentially improves thrombosis prognosis. The patient’s condition improved after administration of antithrombotic agents. Chemotherapy agents and other factors, including the cancer site and presence of metastatic cancer, influence the risk of CAT. Risk predictor scores are required to assess the risk of CAT and benefits of prophylactic treatment. Prophylactic therapy can be initiated in patients with high-risk CAT, calculated using the modified Khorana and Vienna CAT scores, to prevent thrombosis and improve patient outcomes.Keywords: gallbladder cancer, deep vein thrombosis, cancer-associated thrombosis, Khorana-Vienna CAT score, chemotherapy, thromboprophylaxis
- Published
- 2024
26. The effect of changing pregnancy intentions on preconception health behaviors: a prospective cohort study.
- Author
-
Din, Hena, Singh-Carlson, Savitri, Corliss, Heather, Hartman, Sheri, Madanat, Hala, Su, H, and Strong, David
- Subjects
Adolescent and young adult cancer ,Physical activity ,Preconception health ,Pregnancy intention ,Smoking ,Survivorship care ,Pregnancy ,Young Adult ,Adolescent ,Female ,Humans ,Preconception Care ,Intention ,Prospective Studies ,Cancer Survivors ,Health Behavior - Abstract
PURPOSE: Pregnancy intentions are associated with preconception health behaviors but are understudied among female adolescent and young adult (AYA) cancer survivors. Preconception health is critical for survivors because they face unique risks to fertility and pregnancy from late effects of cancer treatments. This study prospectively assessed the effect of pregnancy intention on physical activity (PA) and smoking behaviors among female AYA survivors. METHODS: A cohort of 1049 female AYA survivors were recruited between 2013 and 2017. Participants were 18-39 years and had completed primary cancer treatment. Longitudinal mixed effects analysis was conducted on participants who completed at least 2 of 4 questionnaires over 1.5 years. Two measures were used to capture multiple dimensions of pregnancy intention. The pregnancy intention score (PIS) captured wanting and planning dimensions and represented a scaled response of low to high intention. The trying dimension captured urgent intention and ranged from not trying, ambivalent (neither attempting nor avoiding pregnancy), and trying now. Intention change was assessed between each consecutive time points. Final analysis was conducted with multiple imputations. RESULTS: Survivors with increased intention measured by trying was associated with increased PA over time (adjusted B [95%CI]: 0.3 [0.01, 0.5]) compared to survivors with no changes or decreased trying intention. PIS was not significantly associated with preconception behaviors. No measure of intention was associated with smoking behavior. CONCLUSIONS: Increasingly urgent pregnancy intention (trying dimension) was associated with higher preconception PA. IMPLICATIONS FOR CANCER SURVIVORS: Screening for immediate intentions can identify AYA survivors in need of early preconception health promotion.
- Published
- 2023
27. Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report
- Author
-
Keerti Wali, Nikita Sankolli, and Savitri Nerune
- Subjects
adherent leucoma ,anterior segment optical coherence tomography ,corneal tear ,interferon alfa 2b ,ocular surface squamous neoplasia ,Ophthalmology ,RE1-994 - Abstract
We report a rare presentation of limbus-sparing ocular surface squamous neoplasia (OSSN) over post-traumatic adherent leucoma. A 32-year-old healthy male presented with a pedunculated fleshy corneal mass overlying an adherent leucoma secondary to self-healed full-thickness corneal laceration, with an adjacent pinguecula separated by a clear normal limbus. AS-OCT confirmed the separation of corneal epithelial mass from underlying iris tissue by thinned scarred corneal stroma. An excisional biopsy with 2mm conjunctival margins and a limbal conjunctival autograft was performed. A feeder vessel was observed at the base of the corneal lesion. Histopathological evaluation showed moderately differentiated squamous cell carcinoma. Adjuvant Interferon alfa 2b chemotherapy for three months ensured complete clearance with no recurrence at follow-up. This case highlights the traumatic etiology of OSSN development without limbal involvement. Immediate corneal tear repair may have prevented its occurrence and the need for long-term chemotherapy.
- Published
- 2024
- Full Text
- View/download PDF
28. Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
- Author
-
Treekitkarnmongkol, Warapen, Shah, Vandna, Kai, Kazuharu, Katayama, Hiroshi, Wong, Justin, Ladha, Farah A., Nguyen, Tristian, Menegaz, Brian, Lu, Wei, Yang, Fei, Mino, Barbara, Tang, Ximing, Gagea, Mihai, Batra, Harsh, Raso, Maria Gabriela, Wistuba, Ignacio I., Krishnamurthy, Savitri, Pinder, Sarah E., Sawyer, Elinor J., Thompson, Alastair M., and Sen, Subrata
- Published
- 2024
- Full Text
- View/download PDF
29. Immunohistochemical assessment of HER2 low breast cancer: interobserver reproducibility and correlation with digital image analysis
- Author
-
Sun, Hongxia, Kang, Eun Young, Chen, Hui, Sweeney, Keith J., Suchko, Michael, Wu, Yun, Wen, Jianguo, Krishnamurthy, Savitri, Albarracin, Constance T., Ding, Qing-Qing, Foo, Wai Chin, and Sahin, Aysegul A.
- Published
- 2024
- Full Text
- View/download PDF
30. The Compton Spectrometer and Imager
- Author
-
Tomsick, John A., Boggs, Steven E., Zoglauer, Andreas, Hartmann, Dieter, Ajello, Marco, Burns, Eric, Fryer, Chris, Karwin, Chris, Kierans, Carolyn, Lowell, Alexander, Malzac, Julien, Roberts, Jarred, Saint-Hilaire, Pascal, Shih, Albert, Siegert, Thomas, Sleator, Clio, Takahashi, Tadayuki, Tavecchio, Fabrizio, Wulf, Eric, Beechert, Jacqueline, Gulick, Hannah, Joens, Alyson, Lazar, Hadar, Neights, Eliza, Oliveros, Juan Carlos Martinez, Matsumoto, Shigeki, Melia, Tom, Yoneda, Hiroki, Amman, Mark, Bal, Dhruv, von Ballmoos, Peter, Bates, Hugh, Böttcher, Markus, Bulgarelli, Andrea, Cavazzuti, Elisabetta, Chang, Hsiang-Kuang, Chen, Claire, Chu, Che-Yen, Ciabattoni, Alex, Costamante, Luigi, Dreyer, Lente, Fioretti, Valentina, Fenu, Francesco, Gallego, Savitri, Ghirlanda, Giancarlo, Grove, Eric, Huang, Chien-You, Jean, Pierre, Khatiya, Nikita, Knödlseder, Jürgen, Krause, Martin, Leising, Mark, Lewis, Tiffany R., Lommler, Jan Peter, Marcotulli, Lea, Martinez-Castellanos, Israel, Mittal, Saurabh, Negro, Michela, Nussirat, Samer Al, Nakazawa, Kazuhiro, Oberlack, Uwe, Palmore, David, Panebianco, Gabriele, Parmiggiani, Nicolo, Parsotan, Tyler, Pike, Sean N., Rogers, Field, Schutte, Hester, Sheng, Yong, Smale, Alan P., Smith, Jacob, Trigg, Aaron, Venters, Tonia, Watanabe, Yu, and Zhang, Haocheng
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Compton Spectrometer and Imager (COSI) is a NASA Small Explorer (SMEX) satellite mission in development with a planned launch in 2027. COSI is a wide-field gamma-ray telescope designed to survey the entire sky at 0.2-5 MeV. It provides imaging, spectroscopy, and polarimetry of astrophysical sources, and its germanium detectors provide excellent energy resolution for emission line measurements. Science goals for COSI include studies of 0.511 MeV emission from antimatter annihilation in the Galaxy, mapping radioactive elements from nucleosynthesis, determining emission mechanisms and source geometries with polarization measurements, and detecting and localizing multimessenger sources. The instantaneous field of view for the germanium detectors is >25% of the sky, and they are surrounded on the sides and bottom by active shields, providing background rejection as well as allowing for detection of gamma-ray bursts and other gamma-ray flares over most of the sky. In the following, we provide an overview of the COSI mission, including the science, the technical design, and the project status., Comment: 8 pages
- Published
- 2023
31. The cosipy library: COSI's high-level analysis software
- Author
-
Martinez-Castellanos, Israel, Gallego, Savitri, Huang, Chien-You, Karwin, Chris, Kierans, Carolyn, Lommler, Jan Peter, Mittal, Saurabh, Negro, Michela, Neights, Eliza, Pike, Sean N., Sheng, Yong, Siegert, Thomas, Yoneda, Hiroki, Zoglauer, Andreas, Tomsick, John A., Boggs, Steven E., Hartmann, Dieter, Ajello, Marco, Burns, Eric, Fryer, Chris, Lowell, Alexander, Malzac, Julien, Roberts, Jarred, Saint-Hilaire, Pascal, Shih, Albert, Sleator, Clio, Takahashi, Tadayuki, Tavecchio, Fabrizio, Wulf, Eric, Beechert, Jacqueline, Gulick, Hannah, Joens, Alyson, Lazar, Hadar, Oliveros, Juan Carlos Martinez, Matsumoto, Shigeki, Melia, Tom, Amman, Mark, Bal, Dhruv, von Ballmoos, Peter, Bates, Hugh, Böttcher, Markus, Bulgarelli, Andrea, Cavazzuti, Elisabetta, Chang, Hsiang-Kuang, Chen, Claire, Chu, Che-Yen, Ciabattoni, Alex, Costamante, Luigi, Dreyer, Lente, Fioretti, Valentina, Fenu, Francesco, Ghirlanda, Giancarlo, Grove, Eric, Jean, Pierre, Khatiya, Nikita, Knödlseder, Jürgen, Krause, Martin, Leising, Mark, Lewis, Tiffany R., Marcotulli, Lea, Nussirat, Samer Al, Nakazawa, Kazuhiro, Oberlack, Uwe, Palmore, David, Panebianco, Gabriele, Parmiggiani, Nicolo, Parsotan, Tyler, Rogers, Field, Schutte, Hester, Smale, Alan P., Smith, Jacob, Trigg, Aaron, Venters, Tonia, Watanabe, Yu, and Zhang, Haocheng
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Compton Spectrometer and Imager (COSI) is a selected Small Explorer (SMEX) mission launching in 2027. It consists of a large field-of-view Compton telescope that will probe with increased sensitivity the under-explored MeV gamma-ray sky (0.2-5 MeV). We will present the current status of cosipy, a Python library that will perform spectral and polarization fits, image deconvolution, and all high-level analysis tasks required by COSI's broad science goals: uncovering the origin of the Galactic positrons, mapping the sites of Galactic nucleosynthesis, improving our models of the jet and emission mechanism of gamma-ray bursts (GRBs) and active galactic nuclei (AGNs), and detecting and localizing gravitational wave and neutrino sources. The cosipy library builds on the experience gained during the COSI balloon campaigns and will bring the analysis of data in the Compton regime to a modern open-source likelihood-based code, capable of performing coherent joint fits with other instruments using the Multi-Mission Maximum Likelihood framework (3ML). In this contribution, we will also discuss our plans to receive feedback from the community by having yearly software releases accompanied by publicly-available data challenges.
- Published
- 2023
- Full Text
- View/download PDF
32. Chitosan-Based Coating Application to Enhance Antimicrobial and Water Vapor Barrier Properties of Industry-Manufactured Paper
- Author
-
Akbarningrum Fatmawati, Natalia Suseno, Emma Savitri, Gloria Tifany Masui, and Felia Azzahra Ivony
- Subjects
chitosan ,antimicrobial ,coated paper ,s. aureus ,e. coli ,Chemistry ,QD1-999 - Abstract
Chitosan, a renowned natural polymer for its wide application, was exploited for industry paper coating solutions. This research aimed to investigate the antimicrobial and water vapor barrier of chitosan solution-coated industry-manufactured paper. The papers were obtained from a national company in Indonesia. The commercially available chitosan with three molecular weight levels (low, medium, and high) was solubilized in sodium acetate buffer and subsequently utilized as the coating solution. The other variable studied was the chitosan concentration in the coating solution, i.e., 1.0, 1.5, and 2.0% (w/w). The antimicrobial activity study was performed by testing against Gram-positive bacteria, represented by Staphylococcus aureus, and Gram-negative bacteria, represented by Escherichia coli. The low molecular weight chitosan showed the best antimicrobial activity and water vapor barrier performance. The 1 %w low molecular weight chitosan-coated paper had shown good antimicrobial activity, against both S. aureus and E. coli, with a growth reduction of > 95 %. The most effective antimicrobial activity against S. aureus was achieved by paper coated with a 1.5% solution of low molecular weight chitosan. For low molecular weight chitosan-coated paper the most effective water vapor barrier was exhibited at 1 %w chitosan concentration. Having shown the best water vapor barrier while maintaining good antimicrobial activity, the 1.0% solution of low molecular weight chitosan was appointed as the best coating solution in this research.
- Published
- 2024
- Full Text
- View/download PDF
33. Knowledge and experience in using 2D and 3D diagnostic imaging among dentists in Surabaya
- Author
-
Nastiti Faradilla Ramadhani, Aga Satria Nurrachman, Yunita Savitri, Alhidayati Asymal, Sri Wigati Mardi Mulyani, Ira Widjiastuti, Muhammad Luthfi, Theodora Valensia, and Hafshah Zhafirah Siri Hanun
- Subjects
knowledge ,dentist ,radiography ,diagnostic ,imaging ,medicine ,Dentistry ,RK1-715 - Abstract
Background: Radiography is essential in dentistry for diagnosis and treatment planning, with two-dimensional imaging such as panoramic and periapical radiographs being commonly used. The advancement to three-dimensional imaging, specifically Cone Beam Computed Tomography (CBCT), provides more detailed visualization but remains underutilized due to limited availability and knowledge among dentists in Indonesia. Purpose: This research is aimed to determine the knowledge and experience of using 2D and 3D diagnostic imaging among dentists in Surabaya. Methods: This research is using an observational descriptive study with a cross-sectional design consisting of 100 dentists who are domiciled in Surabaya and registered with PDGI in Surabaya. Results: The result showed that dentists’ knowledge of 2D diagnostic imaging with a good category has a percentage of 18%, quite good category with 49% and poor category with 33%. Meanwhile, the dentists’ knowledge of 3D diagnostic imaging with a good category has a percentage of 9%, quite good category with 36% and poor category with 55%. Around 88% of respondents have referred their patients for panoramic and periapical radiographs, while only about 22% of dentists have referred their patients for CBCT examinations. Conclusion: The knowledge of dentists regarding 2D diagnostic imaging is quite good, while the knowledge of dentists regarding 3D diagnostic imaging is low. The majority of dentists in Surabaya often refer their patients for panoramic and periapical radiographic examinations compared to referring them for CBCT examinations.
- Published
- 2024
- Full Text
- View/download PDF
34. The development of elema 2.0 for the invertebrate zoology course on the phylum arthropoda topic
- Author
-
Chaidir Adam, Agus Haryono, Elga Araina, and Shanty Savitri
- Subjects
biology education ,digital learning ,elema ,learning materials ,Education (General) ,L7-991 ,Biology (General) ,QH301-705.5 - Abstract
Currently, technology has become an inseparable part of education and learning. Various digital learning tools have been developed and widely used in the classroom. eLEMA (electronic learning materials) was developed as a mobile application that supports learning in the Invertebrate Zoology courses at the Biology Education Program, University of Palangka Raya. At that time, eLEMA was developed to meet the need for electronic learning materials for online learning during the COVID-19 pandemic. Along with the rapid development of technology in recent years, eLEMA needs to be developed further for updates. This research aims to develop eLEMA 2.0 for the Invertebrate Zoology course. This study is a research and development (R & D) using Hannafin & Peck development model to develop eLEMA 2.0 for the Invertebrate Zoology course on the Phylum Arthropoda topic. The development product is the eLEMA 2.0 application for lectures on the Phylum Arthropoda topic in the Invertebrate Zoology course with improvements to the user interface and additional features that support participatory learning and student-centered learning. The results of trials and validation show that all pages and content in this application were successfully opened without any disturbing errors. These results indicate that the development product is feasible to be implemented in the classroom.
- Published
- 2024
- Full Text
- View/download PDF
35. Implementation of the Digital Health Approach to Support Learning for Health Students Based on Bloom’s Taxonomy: A Systematic Review
- Author
-
Savitri Citra Budi, Divi Galih Prasertyo Putri, Kintan Puspitasari, and Al Razi Sena
- Subjects
digital health ,health literacy ,health education ,electronic health records ,health information management ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Objectives Health students’ ability to utilize technology effectively is vital for improving the quality of future healthcare services. Relevant digital health education must be comprehensively integrated into training programs, continuing professional development activities, and school curricula to keep them current. This study investigated the most effective digital health approaches to enhance health students’ cognitive, affective, and psychomotor skills, thereby preparing them for the workforce. Methods A literature review was conducted by searching for articles from 2013 to 2023 in PubMed, Science Direct, ERIC, and Scopus. The search used the PICO model, focusing on experimental studies and digital learning. Results The review identified 26 studies, categorizing digital education methods into platform-based (46.2%), tools-based (30.7%), and training-based approaches (23.1%). Participants included health students (57.7%), healthcare professionals (34.6%), and a combination of both (7.7%). The content materials primarily targeted curriculum objectives (65.4%) and clinical applications (34.6%). The outcomes, classified according to Bloom’s taxonomy, were divided into cognitive (84.6%), affective (76.9%), and psychomotor (46.1%) domains. Conclusions Digital health education benefits from a variety of approaches. A platform-based approach is recommended for delivering theoretical and methodological materials, a tools-based approach for simulations, and a training-based approach for practical skills to enhance the cognitive domain. Both platform-based and training-based approaches are advised to improve the affective and psychomotor dimensions of learning. This study underscores the importance of an integrated digital learning system in health educational institutions to prepare students for evolving health systems and to improve learning outcomes and skill transfer.
- Published
- 2024
- Full Text
- View/download PDF
36. UNRAVELING THE IMPACT OF THE MEMORY, THE COMPETITION, AND THE LINEAR HARVESTING ON A LOTKA-VOLTERRA MODEL
- Author
-
HASAN S. PANIGORO, EMLI RAHMI, DIAN SAVITRI, and LAZARUS KALVEIN BEAY
- Subjects
caputo fractional derivative ,harvesting ,lotka-volterra ,Mathematics ,QA1-939 - Abstract
The harvesting of population has a dominant influence in balancing the ecosystem. In this manuscript, the impact of harvesting in addition to competition, and memory effect on a prey-predator interaction following the Lotka-Volterra model is studied. The mathematical validation is provided by proofing that all solutions of the model are always exist, non-negative, and bounded. Obeying Matignon condition, Lyapunov function, and generalized LaSalle invariance principle, the local and global stability are investigated. To complete the analytical results, some numerical simulations are given to show the occurrence of forward bifurcation and the impact of the memory index. All results state that three possible circumstances may occur namely the extinction of both populations, the prey-only population, and the co-existence of both populations.
- Published
- 2024
- Full Text
- View/download PDF
37. Recurrent ventricular fibrillation as a complication of pediatric Covid-19: a case report
- Author
-
Saptadi Yuliarto, Dyahris Koentartiwi, Herlin Kristanti, Dewangga Primananda Susanto, Takhta Khalasha, Novi Evridayanti, Emi Yulianti, Savitri Laksmi Winaputri, Muchammad Fahrul Udin, Irene Ratridewi, Ery Olivianto, and Kurniawan Taufiq Kadafi
- Subjects
covid-19 ,children ,ventricular fibrillation ,Medicine ,Pediatrics ,RJ1-570 - Abstract
Background. Coronavirus disease 2019 (Covid-19) is infrequently associated with severe complications in children. A recent observation has linked Covid-19 to recurrent ventricular fibrillation in pediatric patients. Case report. We present a distinct case of severe Covid-19 in an 11-year-old male child who was previously healthy but obese. The patient experienced recurrent fibrillation as a complication and underwent multiple defibrillation shocks, ultimately surviving the ordeal. Early on in the management of refractory ventricular fibrillation, the patient was administered amiodarone intravenously. Upon diagnosis, he was found to have pneumonia and hypoxemic respiratory failure, necessitating supplemental oxygen through intubation due to hypoxia. Given the rapid progression of his pneumonia, a treatment regimen including remdesivir and dexamethasone was initiated. Conclusions. This case study could be utilized as a valuable point of reference for healthcare providers treating young patients with Covid-19. It is essential to apply established treatment methods for pediatric Covid-19 to mitigate risks of complications like ventricular fibrillation in children.
- Published
- 2024
- Full Text
- View/download PDF
38. Highly Sensitive Aspartame Electrochemical Sensor in Beverages Sample Using Glassy Carbon Electrode Modified with Boron Doped Nanodiamond/ZnO Nanoparticles Composite
- Author
-
Ilmanda Zalzabhila Danistya Putri, Prastika Krisma Jiwanti, Ganden Supriyanto, Ilmi Nur Indira Savitri, Kiki Adi Kurnia, Widiastuti Setyaningsih, Brian Yuliarto, and Noviyan Darmawan
- Subjects
aspartame ,boron-doped diamond powder ,human & health ,metal oxide nanoparticles ,Technology ,Technology (General) ,T1-995 - Abstract
This study reports an electrochemical sensor for detecting aspartame using square wave voltammetry (SWV) on ZnONP/BDDNP electrode. ZnONP/BDDNP was able to oxidize aspartame at a potential of 0.34 V in a phosphate buffer solution pH 2.0 with a current of 80.1 µA. The limit of detection (LOD) was found to be 0.07 µM, the limit of quantitation (LOQ) was 0.25 µM and sensitivity was 1.23 µA µM-1. The relative standard deviation (RSD) was 1.6%, less than 5% indicating that ZnONP/BDDNP has good precision. ZnONP/BDDNP showed better results compared with the BDDNP electrode. The developed method showed good linearity in the concentration range of 30-100 µM. This method was successfully applied to determine aspartame in beverage samples with a recovery range of 85-110%. This shows that ZnONP/BDDNP with the suggested method is potentially applied in practical used.
- Published
- 2024
- Full Text
- View/download PDF
39. Characterization of Robusta Coffee Powder with Addition of Palm Sugar and Vanilla Powder to Improve The Quality of Robusta Coffee (Coffea canephora Pierre)
- Author
-
Canserlita Puteri Herliani, Dyah Ayu Savitri, Hasbi Mubarak Suud, and Muhammad Ghufron Rosyady
- Subjects
Agriculture ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Bondowoso Robusta Coffee is a type of Robusta coffee that has a distinctive taste and high quality. The distinctive taste and high quality are obtained from the results of harvest management and post-harvest processing in accordance with Standard Operating Procedures (SOP). This research will be carried out by testing the characteristics of Robusta ground coffee with a mixture of palm sugar and vanilla flavoring to improve the quality of Robusta ground coffee. This was done by knowing the physicochemical and organoleptic properties of the mixed Robusta ground coffee. The aim of this research is to determine the interaction between roasting level and the composition of palm sugar and vanilla powder on the physiochemical and organoleptic properties of 3 in 1 Robusta Coffee. This research uses an experimental plan arranged factorially with the basic pattern of a Completely Randomized Design (CRD) with 4 replications. This design has two factors, the first factor is the roasting level and the second is the mixture composition. The results of this research show (1) The interaction of Roasting Level and Mixture (palm sugar and vanilla powder) has no significant effect on all observed variables such as water content, Brix content, pH value, and powder bulk density. (2) The effect of the main level of roasting has a very significant effect on the observed variables of rainfall density and an insignificant effect on the variables of air content, Brix content and pH value. (3) The effect of the main mixture has a very significant effect on the observed variables of air content, Brix content and powder bulk density and has no significant effect on the variable pH value.
- Published
- 2024
- Full Text
- View/download PDF
40. Expired Lircetam drug as a corrosion inhibitor for low-carbon steel in 1 M HCl: Experimental, theoretical, and quantum chemical insights
- Author
-
Savitri Danappa Kotabagi, S.K. Rajappa, Ragini L. Minagalavar, Manohar R. Rathod, J.G. Suma, and Ashok M. Sajjan
- Subjects
Low-carbon steel ,Corrosion inhibition ,Electrochemical tests ,Lircetam drug ,Industrial electrochemistry ,TP250-261 - Abstract
Lircetam (LRTM) is a drug used for the treatment of epilepsy. The disposal of expired LRTM poses environmental risks, yet it retains active components that can be repurposed. This research investigates the application of expired LRTM as a corrosion inhibitor for low-carbon steel (LCS) in a 1 M HCl solution. Electrochemical methods, including Tafel polarization (PDP) and electrochemical impedance spectroscopy (EIS), alongside weight loss measurements, were employed to evaluate the efficacy of LRTM in protecting LCS against corrosion. The highest inhibition efficiencies was reported 98.16%, at 60 ppm optimal concentration. The adsorption behavior of LRTM molecules follows the Langmuir isotherm model. Surface analysis through scanning electron microscopy (SEM) and atomic force microscopy (AFM) showed that the LCS surface remained largely unaffected by the acid solution in the presence of LRTM. Contact angle (CA) measurements revealed that the adsorption of LRTM molecules increased the hydrophobicity of the LCS surface. LRTM acts as a mixed-type inhibitor, impeding both anodic and cathodic reactions. Density functional theory (DFT) calculations and molecular dynamics (MD) simulations provided further insight into the chemical interactions between LRTM and the LCS surface. This research introduces the novel application of expired lircetam, highlighting its non-toxic nature and cost-effectiveness, making it a promising alternative for corrosion prevention in industrial applications. This study investigates the dual role of Lircetum in addressing expired pharmaceutical waste and developing an efficient corrosion inhibitor for LCS in acidic environments. Repurposing expired Lircetum provides a sustainable solution to environmental hazards while demonstrating high corrosion inhibition efficiency.
- Published
- 2025
- Full Text
- View/download PDF
41. C-reactive protein as a diagnostic marker for ovarian carcinoma
- Author
-
Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, and Irma Savitri
- Subjects
C-reactive protein ,ovarian carcinoma ,ovarian cyst ,Medicine - Abstract
Ovarian carcinoma is a leading cause of death in gynecological cancers, making early detection crucial for improving survival rates. C-reactive protein (CRP) has shown promise as a cost-effective biomarker to distinguish ovarian carcinoma from benign ovarian masses. Elevated CRP levels are associated with an increased risk of ovarian cancer. This cross-sectional study included 87 patients: 59 with ovarian carcinoma and 28 with ovarian cysts. The aim was to evaluate CRP as a diagnostic marker to improve early detection and clinical management of ovarian carcinoma. CRP levels were measured using the enzyme-linked immunosorbent assay method. Statistical analysis was conducted to assess the differences in CRP levels between the ovarian carcinoma group and the ovarian cyst group. All statistical analyses were performed using the Statistical Program for Social Sciences (IBM SPSS 24, IL, USA). Most subjects in the study were 50 years old or younger (69%) and had ovarian carcinoma (67.8%). Age over 50 [odds ratio (OR) 5.71, p=0.01] and menopausal status (OR 4.72, p=0.01) were significant risk factors for ovarian carcinoma. No significant difference in CRP levels was found between ovarian carcinoma and ovarian cyst patients (p=0.23). Based on the results, CRP cannot be used as an effective predictor to differentiate ovarian carcinoma from ovarian cysts.
- Published
- 2025
- Full Text
- View/download PDF
42. Sistem Pemandian dan Pembersihan Sangkar Burung Murai Batu Otomatis Berbasis Internet Of Things
- Author
-
Valiyana Savitri and Nefy Puteri Novani
- Subjects
Sensor Turbidity, Sensor Load Cell, Sensor Ultrasonik, Sensor Passive Infrared, ESP32, Murai Batu ,Computer software ,QA76.75-76.765 ,Computer engineering. Computer hardware ,TK7885-7895 - Abstract
This study designs an automated bathing and cage cleaning system for Murai Batu birds based on the Internet of Things (IoT) using the NodeMCU ESP32 microcontroller. The system integrates a turbidity sensor to monitor water clarity, an ultrasonic sensor to measure water level, and a load cell sensor to detect waste weight. Additionally, a PIR sensor is used to detect the bird's presence, while a stepper motor and relay are employed to automate the opening and closing of the door. Cage cleaning is performed by operating a belt conveyor driven by a DC motor, and water replacement is conducted using a water pump. All components are controlled by the NodeMCU ESP32, with monitoring facilitated through the Telegram application. The implementation results demonstrate that the system is effective, achieving sensor accuracies of 95.4%, 97.7%, and 97.36%, respectively, and providing convenience for bird owners in managing and monitoring the system remotely.
- Published
- 2025
- Full Text
- View/download PDF
43. VALIDATING THE INTERPERSONAL MINDFULNESS IN PARENTING (IM-P) SCALE FOR PARENTS IN INDONESIA
- Author
-
Khairunnisa Fahira Dumbi, Carrenina Prilly Juaninda, and Luh Surini Yulia Savitri
- Subjects
mindful parenting ,parenting instrument ,psychometric ,reliability ,validity ,The family. Marriage. Woman ,HQ1-2044 - Abstract
The concept of mindful parenting, derived from the broader framework of mindfulness, has gained increasing recognition in Indonesian parenting practices over recent years. However, the Interpersonal Mindfulness in Parenting (IM-P) instrument, which possesses strong psychometric properties, has not yet been available in Bahasa. The purpose of this study is to adapt the IM-P instrument into a valid and reliable Indonesian version. The IM-P was translated and adapted into Indonesian, involving a sample of 735 parents (M = 36.63; SD = 7.354) with children aged 3 to 17 years. Using a random sampling procedure, the first sample (n = 367) was used for Exploratory Factor Analysis (EFA), while the second sample (n = 368) was used for Confirmatory Factor Analysis (CFA). The study revealed that the Indonesian version of the IM-P consists of 20 items and 4 dimensions: Emotional Awareness of Self and Child, Self-Regulation in Parenting, Non-judgmental and Compassion for Child, and Non-judgmental and Compassion for Self. Overall, the IM-P Indonesia demonstrated good reliability. Additionally, the IM-P Indonesia showed a significant negative correlation with parenting stress, except for the dimension of Non-judgmental and Compassion for Self. These findings suggest that the IM-P is a valid and reliable measure for use within the Indonesian population.
- Published
- 2025
- Full Text
- View/download PDF
44. Microbial surfactants: overview
- Author
-
Kumar, Royal, primary, Pandey, Riya, additional, Tiwari, Savitri, additional, and Singh, Pratichi, additional
- Published
- 2024
- Full Text
- View/download PDF
45. The Formulation of a Body Scrub Combining Sweet Orange Peel (Citrus x sinensis L.) and Coconut Dregs (Cocos nucifera L.) as an Antioxidant
- Author
-
Habieb Riziek, Ghery Arrahman, Anita Savitri, Zahara, Risa Hanifah, Maharini, and M. Rifqi Efendi
- Subjects
Antioxidant ,body scrub ,coconut pulp ,sweet orange ,Chemistry ,QD1-999 - Abstract
The sweet orange peel (Citrus x sinensis L.) possesses antioxidant properties that can be harnessed for developing a pharmaceutical preparation based on natural ingredients, particularly in skin care products such as body scrubs. Meanwhile, coconut pulp (Cocos nucifera L.) has a textural quality that lends itself to use as a scrubbing agent, capable of removing dead skin cells. This study aimed to ascertain the antioxidant activity of body scrub formulations with varying concentrations of extract. The results of the phytochemical screening indicated the presence of alkaloids, flavonoids, tannins, and triterpenoids. Three formulations of body scrub were prepared, designated FI (1.25% extract), FII (2.5% extract), and FIII (5% extract). The results of the physical tests demonstrated that the organoleptic, pH, spreadability, and adhesion tests met the requisite standards. In the antioxidant activity test with the DPPH reagent, the IC50 value of each formula is as follows: The results demonstrated that the IC50 value of each formula was 7.28 ppm (very strong) for FI, 11.839 ppm (very strong) for FII, and 17.354 ppm (very strong) for FIII.
- Published
- 2024
- Full Text
- View/download PDF
46. Social-economic and environment impacts for a fish reverse supply chain: A mixed integer linear optimization approach
- Author
-
Iwan Vanany, Ivan Darma Wangsa, Niken Anggraini Savitri, Rizki Revianto Putera, Muhammad Cholili, Berto Mulia Wibawa, Lukman Atmaja, and Ming-Lang Tseng
- Subjects
Reverse supply chain ,Mixed-integer linear programming ,environmental Impacts ,Social-economic insight ,Carbon emissions ,Systems engineering ,TA168 ,Marketing. Distribution of products ,HF5410-5417.5 - Abstract
This study contributes to the fish reverse supply chain due to a lack of social, economic and environmental impacts. This study aims to develop a mathematical model for the fish reverse supply chain with a multi-echelon, multiple periods, and products. The model optimizes total profit, job opportunities, and carbon emissions simultaneously. The proposed model provides social-economic insight for governments and industries to understand the increasing job opportunities if fish gelatine and powder industries can process fish waste. A sensitivity analysis shows that the supply of raw fish, selling prices, and purchasing costs are sensitive to total profit, carbon emissions, and job opportunities. The results show that the total profit for five months is USD 1,437,837, and the most significant contribution to the total cost is the costs of purchasing, emission costs, and production costs, which are 43.83%, 24.02%, and 18.15%, respectively. These results can assist managers in making optimal decisions regarding raw fish supply, halal fish gelatine, and fish powder production, impacting strategic, tactical, and operational policies.
- Published
- 2024
- Full Text
- View/download PDF
47. A bibliometric analysis corporate university discourse
- Author
-
Renny Savitri, Ladiatno Samsara, Benedicta Retna Cahyarini, Madya Putra Yaumil Ahad, Rori Gusparirin, and Nurhuda Firmansyah
- Subjects
corporate university ,bibliometric analysis ,VOSviewer software ,Bibliography. Library science. Information resources - Abstract
Introduction This research investigate scientific publication trends related to corporate university themes. All publications are indexed in the Scopus database from the first publication until April 2022. Limited discussion of corporate university using bibliometric analysis in Scopus is the novelty of this paper. Data Collection Methods Using bibliometric analysis with data visualization performed with VOS viewer application version 1.6.18 Results and Discussion.. The first publication related to the corporate university theme emerged in 1985 and reached its peak in 2017, then tended to decrease until April 2022. The US is the most influential country in the corporate university theme in both the number of publications and number of citations. Intellectual Partnership Consulting from the UK is the most influential organization with the highest number of publications. Whereas Chairman of Paradigm Shift International contribute as the most cited publication. Conclusion. "Corporate University" has become an interesting research theme in HR development for the last four decades. It is shown from the increase of the publication numbers and authors from various organizations accros the world. Furthermore, the authors’ perspective in terms of corporate university varies. The study should inform researchers, practitioners and policy makers to improve and enhance corporate university governance.
- Published
- 2024
- Full Text
- View/download PDF
48. P-99 CHARACTERIZATION OF PATIENTS WITH LIVER CIRRHOSIS, ITS COMPLICATIONS AND SURVIVAL.
- Author
-
Dayron Páez Suárez, Juan Ramón Pineda Paz, Mayra Zoa Más Martínez, Enrique Rogelio Arús Soler, Gabriel Gonzalo Astorga Moreno, and Rhonda Savitri Mohan
- Subjects
Specialties of internal medicine ,RC581-951 - Abstract
Conflict of interest: No Introduction and Objectives: The complications of liver cirrhosis significantly influence the survival of these patients.Objective: Characterize patients with liver cirrhosis, its complications and survival. Patients / Materials and Methods: Longitudinal prospective study in the Gastroenterology service in a tertiary hospital of national reference. Period: December 2017 - December 2019. Sample: 52 patients who met selection criteria. Clinical variables were recorded to determine the stage of cirrhosis, the Child‐Pugh and the complications presented. Data were summarized, association between variables was evaluated, and survival was estimated. Results and Discussion: The average age was 59 ± 11.0 years, men predominated (57.7%), alcohol consumption as the most frequent etiology (53.3%), ascites decompensation as the debut form (55.8%) and complication most incident (75%) followed by jaundice (40.4%) and encephalopathy (28.8%). F1 esophageal varices were the most confirmed endoscopic finding (26.9%), with stage 4 cirrhosis (69.2%) and Child-Pugh B (55.8%) predominating in the sample. At the end of the study, 19.2% of the patients died, overall survival was 89.0% at one year and 55.1% at two years, the association of the Child-Pugh scale as a predictor of mortality being statistically significant. Conclusions: An association was demonstrated between the causes of cirrhosis and sex, mainly alcohol in men. One fifth of the patients died and overall survival showed a notable decrease at one year and two years, the estimate of survival according to the Child-Pugh scale being significant.
- Published
- 2024
- Full Text
- View/download PDF
49. Intercultural Pragmatic Analysis of 'Sorry' in Inflight Service Refusals by Flight Attendants: A Case Study of a Thai Airline
- Author
-
Khanapornvorakarn, Sompong and Gadavanij, Savitri
- Abstract
In seeking to investigate the use of "sorry" in interlanguage refusal by Thai EFL users in an intercultural communication context, the present study collected data from Thai flight attendants who served passengers on international flights for a Thai airline, so as to examine how "sorry" is adopted in refusals in the context of in-flight services. A discourse completion task (DCT) questionnaire was employed to solicit responses from ten male and ten female participants. Through Weerachairattana and Wannaruk's (2016) classification of refusals and the syntactical construction of "sorry" by Arizavi and Choubsaz (2018), the data gathered were coded and analyzed in terms of semantic formulas, strategies used, and pragmatic transfer. Findings revealed that "sorry" conveyed conventional implicatures as "a marker for refusals," "expressing an excuse or reason," and "introducing a reason or showing sympathy," attested by the constructions used in refusals. The term was also uttered with an "excuse, reason, or explanation" to express politeness and regret in refusals in which pragmatic transfer was produced by flight attendants due to L1 pragmatic norms. These different functions of "sorry" used in refusals were bound to surrounding and situational contexts. However, gender differences did not have much bearing on the use of "sorry" in refusals because organizational culture plays a more significant part in discourse in professional contexts. This study was conducted in the hope that it could contribute to interlanguage pragmatic study, particularly to expand our understanding of intercultural communication between English native speakers and EFL learners and users.
- Published
- 2022
50. 'They Serve as Good Models,' but 'Their Works Are Too Expensive': US Hegemony in Citation Practices in EFL Writing Textbooks in Thailand
- Author
-
Rerkwanchai, Kiatipong and Gadavanij, Savitri
- Abstract
Citation is an important element in academic writing. Although emphasis has been primarily placed on the linguistic features of citation with pedagogical aims, this study investigates citation practices from a decolonial perspective by examining the concept of the "gesture of exclusion" (Connell, 2007) or the tendency to cite scholarship produced by Western-based writers. Focusing on a non-Anglophone and non-colonized country, we examined the extent to which Thai textbook authors practice the gesture of exclusion by analyzing the references in their publications. Data were collected from six locally produced English as a foreign language university-level writing textbooks and one author interview. Findings showed that in a non-colonized country, the dominance of works by US-based scholars was clearly discernible, but works by Thai academics seemed to be finding footing as well. Author's decisions to refer to either Anglophone or local scholarship were shaped by three factors: native-speakerism, capitalism, and rhetorical appeals. Paradoxically, the tension between the two competing western discourses, native-speakerism and capitalism, contributed significantly to a higher visibility of works by local scholars. It is suggested that as this tension mounts, it could help promote a more inclusive academic discipline, in terms of academic citations. Implications for writing teachers and material writers are also discussed.
- Published
- 2022
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.