516 results on '"Savvides, Savvas N"'
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2. Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
3. Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice
4. Improving de novo protein binder design with deep learning
5. Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
6. Unexpected complexity of the ammonia monooxygenase in archaea
7. Mechanism of receptor assembly via the pleiotropic adipokine Leptin
8. EGOC inhibits TOROID polymerization by structurally activating TORC1
9. CRISPR-SID : Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
10. Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis: A molecular insight
11. Design of protein-binding proteins from the target structure alone
12. The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
13. Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
14. Correction to: Unexpected complexity of the ammonia monooxygenase in archaea
15. Structural basis of cytokine-mediated activation of ALK family receptors
16. Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1
17. Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish
18. Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors
19. The crystal structure of the archetypical Nictaba plant lectin reveals the molecular basis for its carbohydrate-binding properties
20. Ym1 protein crystals promote type 2 immunity
21. Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents
22. Ym1 protein crystals promote type 2 immunity
23. Author Response: Ym1 protein crystals promote type 2 immunity
24. Ym1 protein crystals promote type 2 immunity
25. Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
26. Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase
27. Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding
28. Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms
29. IL-33trap is a novel IL-33–neutralizing biologic that inhibits allergic airway inflammation
30. Structural basis of latent TGF-β1 presentation and activation by GARP on human regulatory T cells
31. Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors
32. Disruption of endocytosis through chemical inhibition of clathrin heavy chain function
33. Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle
34. Attenuated CSF‐1R signalling drives cerebrovascular pathology
35. Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity
36. DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance
37. Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23
38. Small-molecule inhibitors get pro-inflammatory TNF into shape
39. Structural basis of cytokine-mediated activation of ALK family receptors
40. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis
41. Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
42. Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha
43. Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9)
44. Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
45. Mechanism of receptor assembly via the pleiotropic adipokine Leptin
46. Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures
47. Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27
48. Structure and oligomerization of the periplasmic domain of GspL from the type II secretion system of Pseudomonas aeruginosa
49. Improving de novo Protein Binder Design with Deep Learning
50. The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
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