Search

Your search keyword '"Sawyer, Kristi"' showing total 24 results
Start Over Author "Sawyer, Kristi"
24 results on '"Sawyer, Kristi"'

1. Feasibility, clinical efficacy, and well-being outcomes of an online singing intervention for postnatal depression in the UK: SHAPER-PNDO, a single-arm clinical trial

Author

Bind, Rebecca H., Sawyer, Kristi, Hazelgrove, Katie, Rebecchini, Lavinia, Miller, Celeste, Ahmed, Subeyda, Dazzan, Paola, Sevdalis, Nick, Bakolis, Ioannis, Davis, Rachel, Lopez, Maria Baldellou, Woods, Anthony, Crane, Nikki, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Greenwood, Lorna, Perkins, Rosie, Fancourt, Daisy, Pariante, Carmine M., and Estevao, Carolina

Published
2023
Full Text
View/download PDF

3. Online singing interventions for postnatal depression in times of social isolation: a feasibility study protocol for the SHAPER-PNDO single-arm trial

Author

Bind, Rebecca H., Estevao, Carolina, Fancourt, Daisy, Hazelgrove, Katie, Sawyer, Kristi, Rebecchini, Lavinia, Miller, Celeste, Dazzan, Paola, Sevdalis, Nick, Woods, Anthony, Crane, Nikki, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Greenwood, Lorna, Bakolis, Ioannis, Lopez, Maria Baldellou, Davis, Rachel, Perkins, Rosie, and Pariante, Carmine M.

Published
2022
Full Text
View/download PDF

6. Gender inequalities in trajectories of depressive symptoms among young people in London and Tokyo: a longitudinal cross-cohort study.

Author

Knowles, Gemma, primary, Stanyon, Daniel, additional, Yamasaki, Syudo, additional, Miyashita, Mitsuhiro, additional, Gayer-Anderson, Charlotte, additional, Endo, Kaori, additional, Usami, Satoshi, additional, Niimura, Junko, additional, Nakajima, Naomi, additional, Baba, Kaori, additional, Advisory Group, TTC Youth, additional, Richards, Thai-sha, additional, Kitisu, Jonas, additional, Hashi, Adna, additional, Clement-Gbede, Karima Shyan, additional, Tettey, Niiokani, additional, Davis, Samantha, additional, Lowis, Katie, additional, Buckley, Verity, additional, Moreno-Agostino, Dario, additional, Putzgruber, Esther, additional, Crudgington, Holly, additional, Woodhead, Charlotte, additional, Sawyer, Kristi, additional, Keyes, Katherine M, additional, Dyer, Jacqui, additional, Ando, Shuntaro, additional, Kasai, Kiyoto, additional, Hiraiwa-Hasegawa, Mariko, additional, Morgan, Craig, additional, and Nishida, Atsushi, additional

Published
2023
Full Text
View/download PDF

8. ##107 - - Impact of Online Singing Sessions on Mother and Offspring HPA Axis Functioning

Author

Sawyer, Kristi, Bind, Rebecca H., Hazelgrove, Katie, Rebecchini, Lavinia, Estevao, Carolina, Miller, Celeste, Ahmed, Subeyda, Dazzan, Paola, Sevdalis, Nick, Bakolis, Ioannis, Davis, Rachel, Lopez, Maria Baldellou, Woods, Anthony, Crane, Nikki, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Greenwood, Lorna, Perkins, Rosie, Fancourt, Daisy, and Pariante, Carmine M.

Published
2024
Full Text
View/download PDF

12. Contributors

Author

Ahmetspahic, Diana, primary, Alferink, Judith, additional, Anderson, George, additional, Arandjelovic, Katarina, additional, Arolt, Volker, additional, Baune, Bernhard T., additional, Benros, Michael Eriksen, additional, Borsini, Alessandra, additional, Bradburn, Steven, additional, Brinker, Dana, additional, Cannon, Abigail R., additional, Capuron, Lucile, additional, Carpenter, Joanne S., additional, Carvalho, André F., additional, Castanon, Nathalie, additional, Choudhry, Mashkoor A., additional, Ciobanu, Liliana G., additional, Cleare, Anthony J., additional, Corrigan, Frances, additional, Dannlowski, Udo, additional, Doolin, Kelly, additional, Engelen, Jennifer, additional, Eyre, Harris A., additional, Farzana, Farheen, additional, Flor-Henry, Sophie, additional, Förster, Katharina, additional, Fourrier, Célia, additional, Frodl, Thomas, additional, Grande, Iria, additional, Gregory, Jonathan M., additional, Hammer, Adam M., additional, Hannan, Anthony J., additional, Hickie, Ian B., additional, Holmes, Joshua, additional, Hutchinson, Mark R., additional, Jawahar, Magdalene C., additional, Jörgens, Silke, additional, Köhler-Forsberg, Ole, additional, Lamers, Femke, additional, Lavretsky, Helen, additional, Licinio, Julio, additional, Lowry, Christopher A., additional, Maes, Michael, additional, Mak, Michael, additional, Martin-Santos, Rocío, additional, McIntyre, Roger S., additional, Merrill, David A., additional, Milaneschi, Yuri, additional, Mondelli, Valeria, additional, Müller, Norbert, additional, Murgatroyd, Chris, additional, Musker, Michael, additional, Najjar, Souhel, additional, Nettis, Maria A., additional, Nikkheslat, Naghmeh, additional, Opel, Nils, additional, Oriolo, Giovanni, additional, Pahlajani, Silky, additional, Pariante, Carmine M., additional, Parletta, Natalie, additional, Penninx, Brenda W.J.H., additional, Raison, Charles L., additional, Redlich, Ronny, additional, Renoir, Thibault, additional, Rook, Graham A.W., additional, Rosenblat, Joshua D., additional, Sawyer, Kristi M., additional, Scott, Elizabeth M., additional, Singh, Ajeet B., additional, Singhal, Gaurav, additional, Steiner, Johann, additional, Strawbridge, Rebecca, additional, Toben, Catherine, additional, Tozzi, Leonardo, additional, Vieta, Eduard, additional, Wong, Ma-Li, additional, Young, Allan H., additional, and Zunszain, Patricia A., additional

Published
2018
Full Text
View/download PDF

14. Study protocol: randomised controlled hybrid type 2 trial evaluating the scale-up of two arts interventions for postnatal depression and Parkinson’s disease

Author

Soukup, Tayana, primary, Davis, Rachel E, additional, Baldellou Lopez, Maria, additional, Healey, Andy, additional, Estevao, Carolina, additional, Fancourt, Daisy, additional, Dazzan, Paola, additional, Pariante, Carmine, additional, Dye, Hannah, additional, Osborn, Tim, additional, Bind, Rebecca, additional, Sawyer, Kristi, additional, Rebecchini, Lavinia, additional, Hazelgrove, Katie, additional, Burton, Alexandra, additional, Manoharan, Manonmani, additional, Perkins, Rosie, additional, Podlewska, Aleksandra, additional, Chaudhuri, Ray, additional, Derbyshire-Fox, Fleur, additional, Hartley, Alison, additional, Woods, Anthony, additional, Crane, Nikki, additional, Bakolis, Ioannis, additional, and Sevdalis, Nick, additional

Published
2022
Full Text
View/download PDF

15. Additional file 2 of Online singing interventions for postnatal depression in times of social isolation: a feasibility study protocol for the SHAPER-PNDO single-arm trial

Author

Bind, Rebecca H., Estevao, Carolina, Fancourt, Daisy, Hazelgrove, Katie, Sawyer, Kristi, Rebecchini, Lavinia, Miller, Celeste, Dazzan, Paola, Sevdalis, Nick, Woods, Anthony, Crane, Nikki, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Greenwood, Lorna, Bakolis, Ioannis, Lopez, Maria Baldellou, Davis, Rachel, Perkins, Rosie, and Pariante, Carmine M.

Subjects
stomatognathic diseases, fluids and secretions, stomatognathic system, health care facilities, manpower, and services, education
Abstract

Additional file 2. Saliva collection booklet

Published
2022
Full Text
View/download PDF

16. Additional file 1 of Online singing interventions for postnatal depression in times of social isolation: a feasibility study protocol for the SHAPER-PNDO single-arm trial

Author

Bind, Rebecca H., Estevao, Carolina, Fancourt, Daisy, Hazelgrove, Katie, Sawyer, Kristi, Rebecchini, Lavinia, Miller, Celeste, Dazzan, Paola, Sevdalis, Nick, Woods, Anthony, Crane, Nikki, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Greenwood, Lorna, Bakolis, Ioannis, Lopez, Maria Baldellou, Davis, Rachel, Perkins, Rosie, and Pariante, Carmine M.

Subjects
stomatognathic diseases, fluids and secretions, stomatognathic system
Abstract

Additional file 1. Saliva sample collection, storage and analysis procedures.

Published
2022
Full Text
View/download PDF

17. SHAPER-PND trial: clinical effectiveness protocol of a community singing intervention for postnatal depression

Author

Estevao, Carolina, primary, Bind, Rebecca, additional, Fancourt, Daisy, additional, Sawyer, Kristi, additional, Dazzan, Paola, additional, Sevdalis, Nick, additional, Woods, Anthony, additional, Crane, Nikki, additional, Rebecchini, Lavinia, additional, Hazelgrove, Katie, additional, Manoharan, Manonmani, additional, Burton, Alexandra, additional, Dye, Hannah, additional, Osborn, Tim, additional, Greenwood, Lorna, additional, Davis, Rachel E, additional, Soukup, Tayana, additional, Arias de la Torre, Jorge, additional, Bakolis, Ioannis, additional, Healey, Andy, additional, Perkins, Rosie, additional, and Pariante, Carmine, additional

Published
2021
Full Text
View/download PDF

19. Scaling-up Health-Arts Programmes: the largest study in the world bringing arts-based mental health interventions into a national health service

Author

Estevao, Carolina, primary, Fancourt, Daisy, additional, Dazzan, Paola, additional, Chaudhuri, K. Ray, additional, Sevdalis, Nick, additional, Woods, Anthony, additional, Crane, Nikki, additional, Bind, Rebecca, additional, Sawyer, Kristi, additional, Rebecchini, Lavinia, additional, Hazelgrove, Katie, additional, Manoharan, Manonmani, additional, Burton, Alexandra, additional, Dye, Hannah, additional, Osborn, Tim, additional, Jarrett, Lucinda, additional, Ward, Nick, additional, Jones, Fiona, additional, Podlewska, Aleksandra, additional, Premoli, Isabella, additional, Derbyshire-Fox, Fleur, additional, Hartley, Alison, additional, Soukup, Tayana, additional, Davis, Rachel, additional, Bakolis, Ioannis, additional, Healey, Andy, additional, and Pariante, Carmine M., additional

Published
2020
Full Text
View/download PDF

22. Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains

Author

Caillet-Saguy, Célia, Toto, Angelo, Guerois, Raphael, Maisonneuve, Pierre, di Silvio, Eva, Sawyer, Kristi, Gianni, Stefano, Wolff, Nicolas, Résonance Magnétique Nucléaire des Biomolécules, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP), Assemblage moléculaire et intégrité du génome (AMIG), Département Biochimie, Biophysique et Biologie Structurale (B3S), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), PM was supported by grants from the Ministère de l’Enseignement Supérieur et de la Recherche and the Fondation pour la Recherche Médicale [FDT20130927999]. KS was a recipient of Erasmus + grant. Work was partly supported by grants from the Italian Ministero dell’Istruzione dell’Università e della Ricerca (Progetto di Interesse ‘Invecchiamento’ to S.G.) and Sapienza University of Rome (C26A155S48 and B52F16003410005 to S.G) and the international division of Institut Pasteur., We thank Pascal Lenormand (Structural Mass Spectrometry and Proteomics Unit) for its technical expertise, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris]

Subjects
phosphatase activity, hydrophobic residues, Binding Sites, Sequence Homology, Amino Acid, Science, PDZ domain, Protein Tyrosine Phosphatase, Non-Receptor Type 4, PDZ Domains, Ligands, Article, Phosphoric Monoester Hydrolases, Kinetics, Allosteric Regulation, Mutation, Proteolysis, Biocatalysis, Medicine, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, sense organs, Amino Acid Sequence, Protein Binding
Abstract

International audience; Human protein tyrosine phosphatase non-receptor type 4 (PTPN4) has been shown to prevent cell death. The active form of human PTPN4 consists of two globular domains, a PDZ (PSD-95/Dlg/ZO-1) domain and a phosphatase domain, tethered by a flexible linker. Targeting its PDZ domain abrogates this protection and triggers apoptosis. We previously demonstrated that the PDZ domain inhibits the phosphatase activity of PTPN4 and that the mere binding of a PDZ ligand is sufficient to release the catalytic inhibition. We demonstrate here that the linker connecting the PDZ domain and the phosphatase domain is involved in the regulation of the phosphatase activity in both PDZ-related inhibition and PDZ ligand-related activation events. We combined bioinformatics and kinetic studies to decipher the role of the linker in the PTPN4 activity. By comparing orthologous sequences, we identified a conserved patch of hydrophobic residues in the linker. We showed that mutations in this patch affect the regulation of the PTPN4 bidomain indicating that the PDZ-PDZ ligand regulation of PTPN4 is a linker-mediated mechanism. However, the mutations do not alter the binding of the PDZ ligand. This study strengthens the notion that inter-domain linker can be of functional importance in enzyme regulation of large multi-domain proteins.

Published
2017
Full Text
View/download PDF

24. Scaling-up Health-Arts Programmes: the largest study in the world bringing arts-based mental health interventions into a national health service

Author

Estevao, Carolina, Fancourt, Daisy, Dazzan, Paola, Chaudhuri, K. Ray, Sevdalis, Nick, Woods, Anthony, Crane, Nikki, Bind, Rebecca, Sawyer, Kristi, Rebecchini, Lavinia, Hazelgrove, Katie, Manoharan, Manonmani, Burton, Alexandra, Dye, Hannah, Osborn, Tim, Jarrett, Lucinda, Ward, Nick, Jones, Fiona, Podlewska, Aleksandra, Premoli, Isabella, Derbyshire-Fox, Fleur, Hartley, Alison, Soukup, Tayana, Davis, Rachel, Bakolis, Ioannis, Healey, Andy, and Pariante, Carmine M.

Abstract

SummaryThe Scaling-up Health-Arts Programme: Implementation and Effectiveness Research (SHAPER) project is the world's largest hybrid study on the impact of the arts on mental health embedded into a national healthcare system. This programme, funded by the Wellcome Trust, aims to study the impact and the scalability of the arts as an intervention for mental health. The programme will be delivered by a team of clinicians, research scientists, charities, artists, patients and healthcare professionals in the UK's National Health Service (NHS) and the community, spanning academia, the NHS and the charity sector. SHAPER consists of three studies – Melodies for Mums, Dance for Parkinson's, and Stroke Odysseys – which will recruit over 800 participants, deliver the interventions and draw conclusions on their clinical impact, implementation effectiveness and cost-effectiveness. We hope that this work will inspire organisations and commissioners in the NHS and around the world to expand the remit of social prescribing to include evidence-based arts interventions.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results