1,171 results on '"Scalp Dermatoses pathology"'
Search Results
2. Differential diagnosis of red scalp: the importance of trichoscopy.
- Author
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Waśkiel-Burnat A, Czuwara J, Blicharz L, Olszewska M, and Rudnicka L
- Subjects
- Humans, Diagnosis, Differential, Dermatitis, Seborrheic diagnosis, Dermatitis, Seborrheic pathology, Rosacea pathology, Rosacea diagnosis, Psoriasis pathology, Psoriasis diagnosis, Dermatomyositis pathology, Dermatomyositis diagnosis, Dermatomyositis diagnostic imaging, Scalp pathology, Dermatitis, Contact pathology, Dermatitis, Contact diagnosis, Erythema pathology, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Scalp Dermatoses diagnostic imaging, Dermoscopy methods, Lichen Planus pathology, Lichen Planus diagnosis
- Abstract
Red scalp is a common complaint that may constitute a diagnostic and therapeutic challenge in daily clinical practice. Among the numerous diseases to cause diffuse scalp erythema are psoriasis, seborrhoeic dermatitis, contact dermatitis, diffuse lichen planopilaris, dermatomyositis and scalp rosacea. Accurate diagnosis is crucial for optimal treatment outcomes. Histology most frequently discriminates the underlying condition, but it requires scalp biopsy. In many cases, the combination of clinical examination and trichoscopy is sufficient for establishing the correct diagnosis. The main trichoscopic features of psoriasis are silver-white scaling, regularly distributed dotted (glomerular) vessels or twisted red loops, and punctate haemorrhages. Yellowish-white scaling and thin arborizing vessels are typical features of seborrhoeic dermatitis. Contact dermatitis is characterized by the presence of yellow exudate and polymorphic vessels, while perifollicular scaling and erythema with the lack of follicular openings are typical findings in lichen planopilaris. In scalp dermatomyositis, tortuous and arborizing vessels with interfollicular and perifollicular pigmentation may be detected. The most characteristic features of scalp rosacea are perifollicular scaling and polygonal/arborizing vessels. This review also summarizes histological features and therapeutic options for these conditions., Competing Interests: Conflicts of interest The authors declare no conflicts of interest., (© The Author(s) 2023. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2024
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3. Multiple Erythematous Papules and Nodules on a Scalp: Challenge.
- Author
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Fawzy MM, Abdelraouf SM, and Korany MM
- Subjects
- Humans, Male, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Female, Scalp pathology
- Abstract
Competing Interests: The authors declare no conflicts of interest.
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- 2024
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4. Multiple Erythematous Papules and Nodules on a Scalp: Answer.
- Author
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Fawzy MM, Abdelraouf SM, and Korany MM
- Subjects
- Humans, Male, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Female, Skin Neoplasms pathology, Scalp pathology
- Abstract
Competing Interests: The authors declare no conflicts of interest.
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- 2024
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5. A rare case of pigmented nodular alopecic lesion on the scalp.
- Author
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Zhu PQ, Yang SX, and Wang Y
- Subjects
- Humans, Alopecia etiology, Alopecia pathology, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Skin Neoplasms pathology, Scalp pathology
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- 2024
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6. Cutis verticis gyrata in a patient with acromegaly: an unusual case and review of literature.
- Author
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Achach O, Assarrar I, Loukili MA, Rouf S, and Latrech H
- Subjects
- Humans, Scalp pathology, Male, Middle Aged, Female, Acromegaly complications, Acromegaly etiology, Scalp Dermatoses complications, Scalp Dermatoses pathology, Scalp Dermatoses etiology, Adenoma complications, Adenoma surgery, Adenoma pathology, Pituitary Neoplasms complications, Pituitary Neoplasms surgery, Insulin-Like Growth Factor I metabolism, Insulin-Like Growth Factor I analysis
- Abstract
Acromegaly is a rare systemic syndrome induced by the overproduction of growth hormone (GH) and insulin-like growth factor type one (IGF1). It is responsible for changes in the skeletal and soft tissue systems and it almost always occurs because of a pituitary adenoma. Amongst the skin complications related to acromegaly, cutis verticis gyrate (CVG) is occasionally found. It is a skin condition characterized by excessive growth of the skin of the scalp, resulting in furrows and folds. Only a few cases of this uncommon association have been reported in the literature. The present clinical case illustrates typical CVG associated with acromegaly. Imaging revealed a pituitary macroadenoma lesion and hormonal evaluation revealed elevated IGF1 and hypopituitarism. The patient underwent a transsphenoidal resection of the pituitary adenoma and the histopathological examination confirmed the diagnosis. The diagnosis of CVG is clinical, so radiologic assessments are generally not necessary. The management of acromegaly associated with CVG depends on controlling the serum levels of GH and IGF1. In some cases, specific injections or surgery can be used to minimize CVG.
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- 2024
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7. Pyogenic granuloma of the scalp arising from a retained bullet fragment after a contralateral skull-penetrating gunshot wound.
- Author
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Ticknor IL, Young PA, Zacher NC, and Bae GH
- Subjects
- Humans, Male, Adult, Scalp pathology, Scalp Dermatoses etiology, Scalp Dermatoses pathology, Foreign Bodies complications, Head Injuries, Penetrating etiology, Granuloma, Pyogenic etiology, Wounds, Gunshot complications
- Abstract
Pyogenic granulomas are benign lesions commonly found on the skin and mucosal surfaces. Although the etiology of pyogenic granuloma is not well understood, some reports have suggested that PG may be caused by impaired wound healing following tissue injury. Rare cases of pyogenic granulomas in the setting of local foreign body have been reported in the literature. Although foreign body reactions have not been identified as a cause of pyogenic granuloma, these reports evidence the need to further investigate this association. We present a 33-year-old man who presented with a pyogenic granuloma on the scalp six years after a contralateral skull-penetrating gunshot wound that resulted in retained bullet fragments.
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- 2024
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8. Multiple hyperkeratotic papules and crusted lesions on the scalp, face, and trunk.
- Author
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Karri S, Bathina A, Kollipara H, and Gandikota R
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- Humans, Face pathology, Facial Dermatoses pathology, Facial Dermatoses diagnosis, Keratosis pathology, Keratosis diagnosis, Scalp pathology, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Torso
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- 2024
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9. Red Nodule on the Scalp in a Healthy Young Man.
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Del Puerto C, Aspillaga S, and Castro A
- Subjects
- Humans, Male, Biopsy, Diagnosis, Differential, Young Adult, Skin Neoplasms pathology, Skin Neoplasms diagnosis, Scalp Dermatoses pathology, Scalp Dermatoses diagnosis, Adult, Scalp pathology
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- 2024
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10. Bilateral scalp ulceration.
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Firpo G, Jones G, Stewart L, and Christie J
- Subjects
- Humans, Scalp Dermatoses pathology, Skin Ulcer pathology, Skin Ulcer etiology, Scalp pathology
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- 2024
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11. Multiple Asymptomatic Dome-Shaped Papules on the Scalp.
- Author
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Charest G, Chandra A, Salem I, LeBlanc RE, and Hamann CR
- Subjects
- Humans, Male, Diagnosis, Differential, Scalp Dermatoses diagnosis, Scalp Dermatoses pathology, Skin Neoplasms pathology, Skin Neoplasms diagnosis, Female, Scalp pathology
- Published
- 2024
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12. Recalcitrant folliculitis decalvans successfully controlled with adalimumab.
- Author
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Ramos J, Silva AM, António AM, and Alves J
- Subjects
- Humans, Treatment Outcome, Scalp Dermatoses drug therapy, Scalp Dermatoses pathology, Anti-Inflammatory Agents therapeutic use, Female, Male, Adult, Adalimumab therapeutic use, Folliculitis drug therapy, Folliculitis pathology
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- 2024
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13. Characterization of a New Variant in ARHGAP31 Probably Involved in Adams-Oliver Syndrome in a Family with a Variable Phenotypic Spectrum.
- Author
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Santaniello C, Faversani A, Corsaro L, Melloni G, Motta S, Mandorino E, Sacco D, Stioui S, Ferrara F, Barteselli D, De Vita D, Manuelli D, and Costantino L
- Subjects
- Female, Humans, Male, Mutation, Pedigree, Phenotype, Ectodermal Dysplasia genetics, Ectodermal Dysplasia pathology, GTPase-Activating Proteins genetics, Limb Deformities, Congenital genetics, Phosphoproteins, Scalp Dermatoses genetics, Scalp Dermatoses congenital, Scalp Dermatoses pathology
- Abstract
Adams-Oliver syndrome is a rare inherited condition characterized by scalp defects and limb abnormalities. It is caused by variants in different genes such as ARHGAP31 . Here, we used an interdisciplinary approach to study a family with lower limb anomalies. We identified a novel variant in the ARHGAP31 gene that is predicted to result in a truncated protein with a constitutively activated catalytic site due to the loss of 688 amino acids involved in the C-terminal domain, essential for protein auto-inhibition. Pathogenic variants in ARHGAP31 exon 12, leading to a premature protein termination, are associated with Adams-Oliver syndrome. Bioinformatic analysis was useful to elucidate the impact of the identified genetic variant on protein structure. To better understand the impact of the identified variant, 3D protein models were predicted for the ARHGAP31 wild type, the newly discovered variant, and other pathogenetic alterations already reported. Our study identified a novel variant probably involved in Adams-Oliver syndrome and increased the evidence on the phenotypic variability in patients affected by this syndrome, underlining the importance of translational research, including experimental and bioinformatics analyses. This strategy represents a successful model to investigate molecular mechanisms involved in syndrome occurrence., Competing Interests: The authors declare no competing interests.
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- 2024
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14. Localized pemphigus vulgaris on scalp: an atypical presentation.
- Author
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Lapena-Casado A, Alcantara-Gonzalez J, Garcia-Garcia M, Perna-Monroy C, Concellon-Donate MA, and Capusan TM
- Subjects
- Humans, Middle Aged, Male, Triamcinolone Acetonide therapeutic use, Triamcinolone Acetonide administration & dosage, Female, Prednisone therapeutic use, Glucocorticoids therapeutic use, Scalp pathology, Acantholysis pathology, Acantholysis diagnosis, Pemphigus pathology, Pemphigus diagnosis, Pemphigus drug therapy, Scalp Dermatoses pathology, Scalp Dermatoses drug therapy, Scalp Dermatoses diagnosis
- Abstract
We present two middle-aged patients with pruritic, crusted scalp erosions. Skin biopsy showed epidermal acantholysis with IgG and C3 intercellular deposits on direct immunofluorescence, leading to the diagnosis of localized pemphigus vulgaris. Resolution of the lesions without relapse occurred after low doses of oral prednisone and intralesional triamcinolone acetonide.
- Published
- 2024
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15. Occipital Scalp Nodule in a Newborn.
- Author
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Nguyen TF, Alfaro MA, Fletcher MB, Messer A, Bode-Omoleye O, and Osswald S
- Subjects
- Humans, Infant, Newborn, Diagnosis, Differential, Scalp Dermatoses diagnosis, Scalp Dermatoses pathology, Skin Neoplasms diagnosis, Skin Neoplasms pathology, Scalp pathology
- Published
- 2024
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16. Cutis verticis gyrata associated with congenital heart disease.
- Author
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Teresa-Palacio M, Akpoke MA, Bah AB, and Aldecoa-Bilbao V
- Subjects
- Humans, Female, Infant, Scalp pathology, Diagnosis, Differential, Rare Diseases diagnosis, Scalp Dermatoses complications, Scalp Dermatoses diagnosis, Scalp Dermatoses pathology, Skin Abnormalities diagnosis, Heart Defects, Congenital diagnosis, Heart Defects, Congenital diagnostic imaging, Connective Tissue Diseases diagnosis
- Abstract
Cutis verticis gyrata (CVG) is a very rare benign disorder characterised by convoluted folds and deep furrows of the scalp that mimic cerebral sulci and gyri. Associations with other pathologies as neuropsychiatric and/or ophthalmologic disorders, secondary cases to inflammatory or neoplastic processes, as well as cases associated to genetic disorders as Turner's syndrome have been reported, but there is no literature describing an association with a congenital structural heart defect and no other underlying condition. We report a case of primary CVG in a 3-week-old female infant associated with an echocardiographic diagnosis of cor triatriatum. Other systemic examination findings and investigations were unremarkable, and the patient has normal neurodevelopment at 1 year old. Aside from the neuropsychiatric and ophthalmologic pathologies commonly associated with primary non-essential CVG, it should be noted that isolated congenital cardiac lesions are also possible, so as to increase our index of suspicion in patients with the disorder., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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17. Erosive pustular dermatosis of the scalp secondary to Erlotinib: A rare occurrence with trichoscopic perspective.
- Author
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Gupta S, Chopra D, and Preeyati
- Subjects
- Female, Humans, Aged, Erlotinib Hydrochloride adverse effects, Scalp pathology, Scalp Dermatoses chemically induced, Scalp Dermatoses drug therapy, Scalp Dermatoses pathology, Antineoplastic Agents therapeutic use
- Abstract
Epidermal growth factor receptor inhibitors are anti-tumour agents that are frequently used for the treatment of neoplastic disorders. In addition to their cutaneous adverse effects, these drugs can rarely lead to erosive pustular dermatosis of the scalp. We report a case of a 67-year-old female who developed erosive pustular dermatosis of the scalp after being started on erlotinib from a trichoscopic perspective, which has been described in literature only once till now., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
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18. Atypical pediatric presentation of alopecic and aseptic nodules of the scalp with features of dissecting cellulitis.
- Author
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Gambichler T, Scheel CH, Chatzipantazi M, Kautz O, Heinzer E, and Boms S
- Subjects
- Male, Humans, Child, Scalp pathology, Alopecia, Cellulitis diagnosis, Cellulitis pathology, Scalp Dermatoses diagnosis, Scalp Dermatoses pathology, Skin Diseases, Genetic
- Abstract
Alopecic and aseptic nodules of the scalp (AANS) and dissecting cellulitis of the scalp (DCS) are rare, closely related conditions of young men that exclusively affect the hair-bearing scalp. We describe a 9-year-old boy who presented with a 6-year history of chronically relapsing, sterile, partially scarring nodules of the scalp and facial skin. Histopathology revealed mixed inflammatory infiltrates consisting of neutrophils, macrophages, lymphocytes, and plasma cells in the deep dermis, consistent with the morphological pattern of suppurative, partly granulomatous dermatitis. The present atypical case is characterized by prepubertal onset and facial involvement which, to our knowledge, has not yet been described before, may be included in the spectrum of "typical" AANS and "typical" DCS., (© 2023 Wiley Periodicals LLC.)
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- 2023
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19. Incidence and time to development of malignancies arising on the scalp of patients with erosive pustular dermatosis based on sex: A retrospective analysis.
- Author
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Shamloul N, Kamrani P, Shamloul G, Kunselman A, Thiboutot D, Billingsley E, and Lam C
- Subjects
- Humans, Scalp pathology, Incidence, Retrospective Studies, Scalp Dermatoses pathology, Neoplasms complications
- Abstract
Competing Interests: Conflicts of interest None disclosed.
- Published
- 2023
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20. Letter from the Editor: Aggressive malignancy in the setting of erosive pustular dermatosis of the scalp.
- Author
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Elston DM
- Subjects
- Humans, Scalp pathology, Scalp Dermatoses pathology, Neoplasms
- Abstract
Competing Interests: Conflicts of interest None disclosed.
- Published
- 2023
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21. Treatment of erosive pustular dermatosis of the scalp: our experience and review of unconventional topical drugs.
- Author
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Di Bartolomeo L, Ceravolo I, Borgia F, Vaccaro F, Guarneri C, and Vaccaro M
- Subjects
- Humans, Aged, Administration, Topical, Dapsone therapeutic use, Alopecia drug therapy, Scalp pathology, Scalp Dermatoses drug therapy, Scalp Dermatoses pathology
- Abstract
Background: Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory disorder of elderly individuals, characterized by relapsing pustular and eroded lesions of the scalp, which may lead to scarring alopecia. Treatment is challenging and classically based on topical and/or oral corticosteroids., Case Report: From 2008 to 2022, we treated fifteen cases of EPDS. We used mainly topical and systemic steroids with good results. Nevertheless, several non-steroidal topical drugs have been described in literature for the treatment of EPDS. We have carried out a brief review of these treatments., Conclusions: Topical calcineurin inhibitors represent a valuable alternative to steroids to avoid skin atrophy. Emerging evidence about other topical treatments, such as calcipotriol, dapsone, zinc oxide, together with photodynamic therapy, are evaluated in our review.
- Published
- 2023
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22. Recalcitrant vegetative and nodular scalp lesions on the vertex in pemphigus patients: an immunocompromised district?
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Kucukoglu R, Atci T, Babuna-Kobaner G, and Buyukbabani N
- Subjects
- Humans, Scalp pathology, Hair Follicle pathology, Pemphigus pathology, Scalp Dermatoses pathology
- Published
- 2023
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23. Cutaneous squamous cell carcinoma in an autosomal-recessive Adams-Oliver syndrome patient with a novel frameshift pathogenic variant in the EOGT gene.
- Author
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Lukas ML, Harald G, Sanz J, Trippel M, Sabina G, and Jochen R
- Subjects
- Female, Frameshift Mutation, Humans, Mutation, N-Acetylglucosaminyltransferases genetics, Scalp pathology, Skull pathology, Carcinoma, Squamous Cell, Ectodermal Dysplasia diagnosis, Ectodermal Dysplasia genetics, Ectodermal Dysplasia pathology, Limb Deformities, Congenital genetics, Scalp Dermatoses congenital, Scalp Dermatoses diagnosis, Scalp Dermatoses genetics, Scalp Dermatoses pathology, Skin Neoplasms diagnosis, Skin Neoplasms genetics
- Abstract
Aplasia cutis congenita (ACC) of the scalp and terminal transverse limb defects (TTLD) are the characteristic findings of Adams-Oliver syndrome (AOS). The variable clinical spectrum further includes cardiac, neurologic, renal, and ophthalmological findings. Associated genes in AOS are in the Notch and the CDC42/Rac1 signaling pathways. Both autosomal-dominant and autosomal-recessive inheritances have been reported, the latter with pathogenic variants in DOCK6 or EOGT. The EOGT-associated recessive type of AOS has been postulated to present a more favorable prognosis. We here report a 12-year-old girl from a refugee family of Iraq with consanguineous parents. She was born with a severe phenotype of AOS presenting a large ACC of the scalp with an underlying skull defect, which was often infected and inflamed. Afterward, additional ulceration developed. Furthermore, the girl showed microcephaly, TTLD on both hands and feet, and neurological findings: spastic paresis, epilepsy and suspicion of intellectual deficit. Molecular genetic analysis (next-generation sequencing) revealed a novel frameshift mutation in the EOGT gene in Exon 13 in homozygous constellation: c.1013dupA p.(Asn338Lysfs*24). A biopsy within an ulceration at the scalp ACC showed a cutaneous squamous cell carcinoma (cSCC) with local invasive growth into the dura, the meninges, and the cortex. Treatment including surgical resection and focal irradiation was not curative and the girl deceased 6 months after initial diagnosis. This report on a patient with AOS and an autosomal-recessive EOGT gene variant dying of a local aggressive cSCC at an ACC lesion shows that close monitoring of ACC is essential., (© 2022 The Authors. American Journal of Medical Genetics Part A published by Wiley Periodicals LLC.)
- Published
- 2022
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24. Nonmelanoma skin cancer in the setting of erosive pustular dermatosis of the scalp: A case series and comment on management implications.
- Author
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Negbenebor NA, Shayegan LH, Cohen LM, and Kroumpouzos G
- Subjects
- Aged, 80 and over, Alopecia pathology, Humans, Scalp pathology, Scalp Dermatoses diagnosis, Scalp Dermatoses etiology, Scalp Dermatoses pathology, Skin Diseases, Vesiculobullous diagnosis, Skin Diseases, Vesiculobullous etiology, Skin Diseases, Vesiculobullous pathology, Skin Neoplasms diagnosis, Skin Neoplasms pathology
- Abstract
Background: Erosive pustular dermatosis of the scalp (EPDS) is an inflammatory cutaneous disorder typically affecting sun-damaged skin of mature individuals. Clinical features of EPDS include sterile pustules and chronic crusted erosions that can be hyperkeratotic and lead to scarring alopecia, atrophy, and telangiectasia. While the condition occurs on sun-damaged skin, a relationship with non-melanoma skin cancer (NMSC) has not been investigated., Objectives: Here we attempted to identify cases of NMSC developing in the setting of EPDS., Methods: Retrospective review of EPDS cases in a dermatology practice., Results: Six patients with mean (range) age 82 (65-92) years that developed NMSC in the setting of EPDS are reported. Five patients had skin phototype I or II associated with substantial solar elastosis. Four patients had history of NMSC. Four patients developed squamous cell carcinoma and two patients basal cell carcinoma on the scalp in the setting of EPDS. A morphologic change in an EPDS lesion, such as a crusted plaque becoming nodular and/or growing significantly within a relatively short period of time, prompted a biopsy that revealed NMSC., Conclusions: NMSC may develop in the setting of EPDS. Possible mechanisms underlying this association include the chronic inflammation associated with EPDS and ultraviolet light exposure. It is crucial to promptly obtain a biopsy in EPDS cases showing signs suspicious for NMSC. Further studies are required to confirm whether NMSC shows a higher prevalence in the setting of EPDS., (© 2022 Wiley Periodicals LLC.)
- Published
- 2022
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25. Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features.
- Author
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Fechine COC, Valente NYS, and Romiti R
- Subjects
- Alopecia diagnosis, Alopecia drug therapy, Alopecia pathology, Humans, Scalp pathology, Lichen Planus diagnosis, Lichen Planus drug therapy, Lichen Planus pathology, Scalp Dermatoses diagnosis, Scalp Dermatoses drug therapy, Scalp Dermatoses pathology
- Abstract
Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities., (Copyright © 2022 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2022
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26. Percutaneous ethanol sclerotherapy is a promising treatment for recalcitrant angiolymphoid hyperplasia with eosinophilia.
- Author
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Galili E, Levi A, Lapidoth M, Barzilai A, Hodak E, and Rimon U
- Subjects
- Administration, Cutaneous, Adult, Aged, Angiolymphoid Hyperplasia with Eosinophilia pathology, Female, Humans, Retrospective Studies, Scalp Dermatoses pathology, Treatment Outcome, Angiolymphoid Hyperplasia with Eosinophilia therapy, Ethanol administration & dosage, Scalp Dermatoses therapy, Sclerotherapy methods
- Abstract
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vascular proliferation, which manifests as characteristic red nodules and papules, mostly located on the scalp and periauricular regions. Patients seek treatment for both aesthetic and functional reasons, as lesions may ulcerate, bleed and itch. Many therapeutic approaches have been reported, with variable success, and relapse remains a troublesome issue. The aim of this study was to report our experience treating ALHE using percutaneous ethanol sclerotherapy (PES). We present a retrospective case series of three patients treated with PES (1-2 treatment sessions each). All patients had tried and failed other treatments prior to this intervention, but following PES treatment, all patients demonstrated significant improvement, which was sustained at follow-up (range 8-17 months after first treatment). Adverse effects were tolerable and transient. This case series demonstrates PES as a promising treatment for recalcitrant ALHE., (© 2021 British Association of Dermatologists.)
- Published
- 2022
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27. Regression of lipoedematous scalp following cryolipolysis using an icepack, with a novel dermoscopic feature of yellow background.
- Author
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Kharkar V, Vishwanath T, and Kamble P
- Subjects
- Alopecia pathology, Dermoscopy, Female, Humans, Lipedema pathology, Middle Aged, Scalp Dermatoses pathology, Alopecia complications, Cryotherapy methods, Lipedema complications, Lipedema therapy, Scalp Dermatoses complications, Scalp Dermatoses therapy
- Abstract
The novel use of cryolipolysis via icepacks, a readily available and inexpensive device, is described for lipoedematous scalp with subjective and objective relief. This is a simple solution to a troublesome, intractable condition and may readily be utilized for patient benefit. Juxtaposing pre and post clinical images., (© 2021 British Association of Dermatologists.)
- Published
- 2022
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28. Primary nonessential cutis verticis gyrata with acne keloidalis nuchae.
- Author
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Nachinolcar SN, Pai V, Shukla P, and Muthuprabhakaran K
- Subjects
- Acne Keloid pathology, Acne Keloid therapy, Adult, Anti-Bacterial Agents therapeutic use, Cryotherapy, Glucocorticoids therapeutic use, Humans, Male, Scalp Dermatoses pathology, Schizophrenia, Triamcinolone therapeutic use, Acne Keloid complications, Scalp Dermatoses complications
- Abstract
Cutis verticis gyrata is a rare disorder characterized by redundant skin forming deep furrows and convolutions. It has been associated with several systemic and cutaneous disorders. We report a case of primary non-essential cutis verticis gyrata in association with acne keloidalis nuchae in a schizophrenic patient.
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- 2021
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29. A Practical Approach to the Diagnosis and Management of Classic Lichen Planopilaris.
- Author
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Svigos K, Yin L, Fried L, Lo Sicco K, and Shapiro J
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- Humans, Scalp pathology, Scalp Dermatoses pathology, Lichen Planus diagnosis, Lichen Planus therapy, Scalp Dermatoses diagnosis, Scalp Dermatoses therapy
- Abstract
Lichen planopilaris is a primary lymphocytic cicatricial alopecia that commonly presents with hair loss at the vertex or parietal scalp. Patients may also have associated scalp itching, burning or tenderness. Due to scarring, hair loss is typically permanent. The main goals of treatment are reducing symptoms and preventing disease progression and further hair loss. Currently, the literature has limited evidence on treatments for this difficult condition, and most available evidence is from case reports and case series. Furthermore, the evidence shows a varied response to therapy, with frequent reports of poor response. This article reviews the diagnosis of this rare disease, summarize the currently available treatments, and provide insights and practices from alopecia experts., (© 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
- Published
- 2021
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30. The chameleon rash: a review of the polyphenotypic dermatoses of dermatomyositis.
- Author
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Connolly A, Gordon PA, Hannah J, and Creamer D
- Subjects
- Calcinosis etiology, Dermatomyositis complications, Facial Dermatoses pathology, Hand Dermatoses pathology, Humans, Leg Dermatoses pathology, Panniculitis etiology, Scalp Dermatoses pathology, Torso pathology, Dermatomyositis pathology, Exanthema pathology
- Abstract
Dermatomyositis (DM) is an autoimmune connective tissue disease that is included in the idiopathic inflammatory myopathies. Cutaneous manifestations are a prominent part of the condition: some skin signs in DM are common to most patients, while other signs are encountered infrequently. A number of features are pathognomic for DM. The demonstration of myositis-specific antibodies (MSAs) in DM has extended the ability to define phenotypic subgroups. It appears that the presence of certain MSAs confers susceptibility to specific clinical features, an association which reveals a serotype-phenotype relationship. In this review article we have provided a detailed summary of common and under-recognized cutaneous manifestations of DM., (© 2021 British Association of Dermatologists.)
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- 2021
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31. Demographic, clinical and dermoscopic features of melanocytic nevi on the scalp.
- Author
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Erfan G, Demircioglu D, Erdemoglu Y, Ozturk Durmaz E, Sezer E, and Sahin S
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Male, Nevus, Pigmented epidemiology, Nevus, Pigmented pathology, Retrospective Studies, Scalp Dermatoses epidemiology, Scalp Dermatoses pathology, Skin Neoplasms epidemiology, Skin Neoplasms pathology, Nevus, Pigmented diagnosis, Scalp Dermatoses diagnosis, Skin Neoplasms diagnosis
- Abstract
Background: The scalp is a special anatomical area and dermoscopic findings of this region may significantly differ from other body parts., Objective: To investigate and compare the clinical and dermoscopic patterns of scalp melanocytic nevi in patients ≤15 years of age and above, and to analyse their relevance to demographic features, atypical mole syndrome (AMS) and total body nevus count (TBNC)., Methods: In this retrospective cohort study, the clinical data and dermoscopic images of patients with scalp melanocytic nevi were retrieved, reviewed and analysed. Demographic, clinical and dermoscopic features were compared in patients ≤15 years of age and above., Results: A total of 196 scalp melanocytic nevi in 126 patients (female/male:64/62; ≤15/>15 years of age: 49/77) with a median age of 18.5 years (range 0-72) were evaluated. Statistically, the globular pattern was significantly higher in all age groups, and the papillomatous pattern was significantly lower in patients ≤15 years of age (P = 0.008 and P = 0.005, respectively). The eclipse pattern was significantly higher, and the homogenous pattern was significantly lower in patients ≤15 years of age with AMS (P = 0.003 and P = 0.014, respectively). Finally, patients ≤15 years of age with 50 to 100 TBNC had a higher eclipse pattern than those with 0 to 25 TBNC., Conclusion: The findings of this retrospective study might implicate that children with eclipse pattern of scalp melanocytic nevi might be 'moley' in the future with an impending risk of AMS. This hypothesis requires confirmation in future prospective studies on a larger cohort of patients., (© 2021 The Australasian College of Dermatologists.)
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- 2021
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32. Psoriasiform rashes as the first manifestation of anti-MDA5 associated myositis.
- Author
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Rathore U, Haldule S, and Gupta L
- Subjects
- Arthritis immunology, Arthritis physiopathology, Dermatomyositis immunology, Dermatomyositis physiopathology, Exanthema pathology, Fever physiopathology, Humans, Male, Muscle Weakness immunology, Muscle Weakness physiopathology, Myositis immunology, Myositis pathology, Myositis physiopathology, Young Adult, Autoantibodies immunology, Dermatomyositis pathology, Ear Auricle pathology, Facial Dermatoses pathology, Interferon-Induced Helicase, IFIH1 immunology, Scalp Dermatoses pathology
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- 2021
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33. Trichilemmal Cysts With Divergent Ductal Differentiation: A Series of 4 Cases.
- Author
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Khan I, Fraga GR, and Dai H
- Subjects
- Adult, Carcinoembryonic Antigen analysis, Epidermal Cyst chemistry, Epidermal Cyst surgery, Female, Humans, Keratin-7 analysis, Male, Middle Aged, Retrospective Studies, Scalp chemistry, Scalp surgery, Scalp Dermatoses metabolism, Scalp Dermatoses surgery, Sweat Glands chemistry, Sweat Glands surgery, Treatment Outcome, Cell Differentiation, Epidermal Cyst pathology, Scalp pathology, Scalp Dermatoses pathology, Sweat Glands pathology
- Abstract
Abstract: Trichilemmal cysts are common clonal tumors with a predilection for the scalp. They are composed of an outer epithelial wall resembling the outer root sheath in the isthmus of the hair follicle and a central core of compact keratin. Sweat duct differentiation is exceptional with only one convincing case reported to date. Here, we sought to characterize the clinicopathological characteristics of sweat duct differentiation in trichilemmal cysts. We reviewed all cases of trichilemmal cyst diagnosed at our institution between 2008 and 2019. Ductal structures were found in 4 of 411 cases (0.97%). Subjects included 2 male and 2 female patients with a median age of 37.5 years (range 34-55). The ducts were lined by attenuated epithelial cells and immunoreactive for polyclonal carcinoembryonic antigen and cytokeratin 7. Ductal differentiation involved a median of 7.5% (range 1%-50%) of the cyst wall. All 4 cases were from the scalp and treated with local excision. No recurrence was identified with a median follow-up period of 1.5 years (range 1-12 years). In summary, sweat duct differentiation in trichilemmal cysts is rare but likely under recognized. Conceptually, we suggest it represents a type of divergent cellular differentiation within a clonal neoplasm rather than a retention cyst or hybrid cyst., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2021
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34. Scalp involvement in patients referred for patch testing: Retrospective cross-sectional analysis of North American Contact Dermatitis Group data, 1996 to 2016.
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Warshaw EM, Kullberg SA, DeKoven JG, Maibach HI, Belsito DV, Silverberg JI, Fowler JF Jr, Atwater AR, Sasseville D, Reeder MJ, Taylor JS, DeLeo VA, Pratt MD, Zug KA, and Fransway AF
- Subjects
- Adult, Aged, Allergens adverse effects, Canada epidemiology, Cross-Sectional Studies, Dermatitis, Allergic Contact epidemiology, Dermatitis, Allergic Contact etiology, Dermatitis, Atopic epidemiology, Dermatitis, Atopic etiology, Dermatitis, Atopic pathology, Dermatitis, Irritant epidemiology, Dermatitis, Irritant etiology, Dermatitis, Seborrheic epidemiology, Dermatitis, Seborrheic etiology, Dermatitis, Seborrheic pathology, Eyeglasses, Female, Hair Dyes adverse effects, Hair Preparations adverse effects, Humans, Irritants adverse effects, Male, Middle Aged, Organ Specificity, Retrospective Studies, Scalp Dermatoses epidemiology, Scalp Dermatoses etiology, United States epidemiology, Dermatitis, Allergic Contact pathology, Dermatitis, Irritant pathology, Patch Tests, Scalp Dermatoses pathology
- Abstract
Background: Scalp conditions are often multifactorial., Objective: To characterize patients with scalp involvement and patch-testing outcomes., Methods: Retrospective cross-sectional analysis of North American Contact Dermatitis Group data (1996-2016). Study groups included patients with scalp involvement (≤3 anatomic sites coded) with or without additional sites., Results: A total of 4.8% of patients (2331/48,753) had scalp identified as 1 of up to 3 affected anatomic sites. Approximately one-third of "scalp-only" individuals had a specific primary diagnosis of allergic contact dermatitis (38.6%), followed by seborrheic dermatitis (17.2%) and irritant contact dermatitis (9.3%). When adjacent anatomic sites were affected, allergic contact dermatitis was more frequently identified as the primary diagnosis (>50%). The top 5 currently clinically relevant allergens in scalp-only patients were p-phenylenediamine, fragrance mix I, nickel sulfate, balsam of Peru, and cinnamic aldehyde. Methylisothiazolinone sensitivity was notable when adjacent anatomic sites were involved. The top 3 specifically identified sources for scalp-only allergens were hair dyes, shampoo/conditioners, and consumer items (eg, hair appliances, glasses)., Limitations: Tertiary referral population., Conclusion: Isolated scalp involvement was less likely to be associated with allergic contact dermatitis than when adjacent anatomic sites were involved. Overlap with multiple diagnoses was frequent, including seborrheic dermatitis, irritant dermatitis, other dermatoses, or all 3. p-Phenylenediamine was the most common allergen., (Published by Elsevier Inc.)
- Published
- 2021
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35. Syringocystadenoma papilliferum of the scalp.
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Perlman KL and Kentosh JB
- Subjects
- Biopsy, Female, Humans, Middle Aged, Scalp Dermatoses surgery, Sweat Gland Neoplasms surgery, Tubular Sweat Gland Adenomas surgery, Scalp Dermatoses pathology, Sweat Gland Neoplasms pathology, Tubular Sweat Gland Adenomas pathology
- Abstract
Syringocystadenoma papilliferum is a rare, benign adnexal tumor of eccrine or apocrine origin that typically presents at birth or before puberty. Syringocystadenoma papilliferum is associated with a nevus sebaceus in about 40% of cases. We present a 50-year old woman with a pink-orange plaque and nodule on the scalp, consistent with syringocystadenoma papilliferum that arose within a nevus sebaceus.
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- 2021
36. Scalp calcinosis in juvenile dermatomyositis.
- Author
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Rathore U and Gupta L
- Subjects
- Calcinosis pathology, Child, Dermatomyositis complications, Humans, Male, Scalp pathology, Scalp Dermatoses pathology, Calcinosis etiology, Dermatomyositis pathology, Scalp Dermatoses etiology
- Published
- 2021
- Full Text
- View/download PDF
37. Approach to treatment of refractory dissecting cellulitis of the scalp: a systematic review.
- Author
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Thomas J and Aguh C
- Subjects
- Adalimumab therapeutic use, Cellulitis pathology, Cellulitis surgery, Humans, Isotretinoin therapeutic use, Lasers, Gas therapeutic use, Lasers, Solid-State therapeutic use, Photochemotherapy, Scalp Dermatoses pathology, Scalp Dermatoses surgery, Skin Diseases, Genetic pathology, Skin Diseases, Genetic surgery, Anti-Bacterial Agents therapeutic use, Cellulitis drug therapy, Scalp Dermatoses drug therapy, Skin Diseases, Genetic drug therapy, Steroids therapeutic use
- Abstract
Background: Dissecting cellulitis is a chronic inflammatory dermatosis that results in disfiguring and painful, purulent lesions. Treatment of patients with disease resistant to standard therapies, including intralesional or topical steroids or antibiotics, can be a dilemma for clinicians., Methods: We performed a systematic review of the literature in November 2018 to find articles which presented treatment options and outcomes of patients who failed prior treatment with standard therapies., Results: We identified 57 articles of interest, with 53 being case studies or series. Isotretinoin was the most often reported, but the response was limited. Biologics and laser therapy were used less often but demonstrated a better chance of remission. X-ray epilation and surgical excision demonstrated the best remission rates but can be complicated by serious morbidity., Conclusion: We propose a regimen for the treatment of recalcitrant cases of dissecting cellulitis. In the future, more robust studies including randomized control trials are needed to identify the preferred treatment options for refractory dissecting cellulitis.
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- 2021
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38. Lichen planopilaris with significant post-inflammatory pigmentary alteration.
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Subramanyam C, Wu H, Puri P, Chambers CJ, and Sivamani RK
- Subjects
- Adult, Dermatologic Agents therapeutic use, Diagnosis, Differential, Humans, Hydroxychloroquine therapeutic use, Lichen Planus drug therapy, Male, Pruritus etiology, Scalp Dermatoses drug therapy, Hyperpigmentation etiology, Lichen Planus complications, Lichen Planus pathology, Scalp Dermatoses complications, Scalp Dermatoses pathology
- Abstract
Lichen planopilaris is an uncommon dermatological manifestation of lichen planus of the scalp and results in cicatricial alopecia. We present a patient with lichen planopilaris and significant post-inflammatory pigmentary alteration, confirmed by histopathology. The patient's case represents a clinically important variation from an expected typical pattern of dyschromia at periphery of alopecic zones in lichen planopilaris.
- Published
- 2021
39. Crusted, ulcerated plaques on the scalp and face.
- Author
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Tisack A, Jiang A, and Veenstra J
- Subjects
- Adrenal Cortex Hormones therapeutic use, Aged, Alopecia diagnosis, Alopecia etiology, Alopecia pathology, Biopsy, Defibrillators adverse effects, Humans, Lost to Follow-Up, Male, Sarcoidosis drug therapy, Sarcoidosis pathology, Scalp Dermatoses diagnosis, Scalp Dermatoses etiology, Face pathology, Sarcoidosis diagnosis, Scalp pathology, Scalp Dermatoses pathology, Skin Ulcer pathology
- Published
- 2021
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- View/download PDF
40. [Scalp disorders in black Africans treated in a dermatology department in Cotonou (Benin): age-sex-specific epidemiological and clinical features].
- Author
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Dégboé B, Koudoukpo C, Habib A, Kouassi A, Djodjo M, Akpadjan F, Adégbidi H, and Atadokpèdé F
- Subjects
- Adolescent, Adult, Age Distribution, Benin epidemiology, Child, Child, Preschool, Cicatrix pathology, Dermatology, Female, Folliculitis epidemiology, Humans, Infant, Infant, Newborn, Male, Middle Aged, Retrospective Studies, Scalp Dermatoses pathology, Sex Distribution, Trichotillomania epidemiology, Young Adult, Alopecia epidemiology, Black People, Cicatrix epidemiology, Scalp Dermatoses epidemiology
- Abstract
Introduction: scalp disorders are related to several factors including ethnicity, gender or age. In black people, they can be caused by intrinsic and extrinsic factors. Very few studies have been conducted in this ethnic group residing in black Africa, hence the purpose of our survey was to highlight the epidemiological and clinical features of age-sex-specific scalp disorders in patients treated in a dermatology department in Cotonou (Benin)., Methods: we conducted a retrospective and descriptive study of all the medical records of new patients coming to consultation in the dermatology department at the National Hospital and University Center (CNHU) of Cotonou over a period of seven years. The main reason for consultation was scalp disorder. Data on epidemiological and clinical features were collected and analyzed with the EPI-Info 7 software., Results: prevalence of scalp disorders was 2.4% (181/7554). Children (0-18 years) accounted for 38.7% (70 patients) and adults 61.3% (111 patients). Children aged 0-10 (54; 29.8%) and adults aged 25-40 (51; 28,2%) were the most affected. Sex ratio was 1.8. Non-alopecizing dermatosis was diagnosed in 10; 5.5% of cases while alopecizing dermatosis in 171 patients (94.5%), of whom 82.9% (151/171) had non-scarring dermatosis and 11.7% (20/171) had scarring dermatosis. The most common conditions were ringworm (41; 22.6%), mainly occurring in 0-10-year-old boys, chronic non-scarring folliculitis (39; 21.5%) mainly occurring in 0-5-year-old boys and 19-40-year-old men, pelade (38; 21%) occurring in both male and female sexes, especially between the ages of 6-10 and 25-40, traction alopecia (17; 9.4%) occurring exclusively in women and mainly in the 25-40-year-old age group, fibrous folliculitis at the nape of the neck (12; 6.6%) occurring exclusively in men from 19 to 50 years, trichotillomania (9; 5%) occurring in both male and female sexes, mainly in children aged 6-10 years and in adults aged 25-40 years, Quinquaud folliculitis decalvans (6; 3.3%) occurring uniformly in both male and female sexes and mainly between 25-40 years of age., Conclusion: scalp disorders mainly affect male patients before puberty and young adults. They were arranged in descending order in non-scarring alopecizing dermatoses, scarring alopecia and non-alopecizing dermatoses., Competing Interests: Les auteurs ne déclarent aucun conflit d´intérêts., (Copyright: Bérénice Dégboé et al.)
- Published
- 2020
- Full Text
- View/download PDF
41. A Solitary Lump on the Scalp.
- Author
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Perinazzo Pauvels LS, da Silva Souza B, and Peruzzo J
- Subjects
- Aged, Biopsy, Choristoma pathology, Female, Humans, Magnetic Resonance Imaging, Meninges pathology, Scalp diagnostic imaging, Scalp Dermatoses pathology, Skin pathology, Choristoma diagnosis, Meninges diagnostic imaging, Scalp Dermatoses diagnosis
- Published
- 2020
- Full Text
- View/download PDF
42. Skin-Colored Nodule on the Scalp of a Middle-aged Man.
- Author
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Khullar G, Agarwal D, and Chandra M
- Subjects
- Animals, Dermis parasitology, Dermis pathology, Diagnosis, Differential, Dirofilaria repens isolation & purification, Dirofilariasis parasitology, Dirofilariasis pathology, Echinococcosis diagnosis, Humans, Loiasis diagnosis, Male, Middle Aged, Onchocerciasis diagnosis, Scalp parasitology, Scalp pathology, Scalp Dermatoses parasitology, Scalp Dermatoses pathology, Skin Diseases, Parasitic parasitology, Skin Diseases, Parasitic pathology, Dirofilariasis diagnosis, Scalp Dermatoses diagnosis, Skin Diseases, Parasitic diagnosis
- Published
- 2020
- Full Text
- View/download PDF
43. Persistent Plaque on the Scalp With Cutis Verticis Gyrata-Like Features: Answer.
- Author
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Roncone K, Gru AA, Greer KE, and Forrester VJ
- Subjects
- Humans, Male, Middle Aged, Pemphigus pathology, Scalp pathology, Scalp Dermatoses pathology
- Published
- 2020
- Full Text
- View/download PDF
44. Erosive pustular dermatosis of the scalp.
- Author
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Marsh RL, Spohn GP, and Kaffenberger JA
- Subjects
- Alopecia etiology, Alopecia pathology, Alopecia prevention & control, Female, Humans, Meningeal Neoplasms radiotherapy, Meningeal Neoplasms surgery, Meningioma radiotherapy, Meningioma surgery, Middle Aged, Mometasone Furoate therapeutic use, Osteomyelitis etiology, Prednisone therapeutic use, Radiosurgery adverse effects, Scalp Dermatoses drug therapy, Scalp Dermatoses pathology, Skin Diseases, Vesiculobullous drug therapy, Skin Diseases, Vesiculobullous pathology, Anti-Inflammatory Agents therapeutic use, Scalp pathology, Scalp Dermatoses diagnosis, Skin Diseases, Vesiculobullous diagnosis
- Abstract
Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory condition commonly associated with antecedent iatrogenic insult. EPDS may be diagnostically challenging owing to a lack of pathognomonic histologic findings and cutaneous manifestations that overlap with alternative dermatologic conditions. Therefore, EPDS may be more common than previously recognized. We present a 60-year-old woman with a four-year history of non-healing scalp erosions, progressive skin atrophy, and scarring alopecia despite intravenous antibiotics and intraoperative debridement who improved with systemic glucocorticoids. Our report emphasizes the importance of early recognition of EPDS when delayed wound healing and erosive disease occur in the setting of iatrogenic injury to the scalp. Timely treatment with systemic anti-inflammatory agents is paramount to prevent cicatricial alopecia and mitigate further scalp insult in EPDS.
- Published
- 2020
45. A novel variant in DOCK6 gene associated with Adams-Oliver syndrome type 2.
- Author
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Alzahem T, Alsalamah AK, Mura M, and Alsulaiman SM
- Subjects
- Ectodermal Dysplasia genetics, Humans, Infant, Limb Deformities, Congenital genetics, Male, Phenotype, Prognosis, Scalp Dermatoses genetics, Scalp Dermatoses pathology, Ectodermal Dysplasia pathology, Guanine Nucleotide Exchange Factors genetics, Limb Deformities, Congenital pathology, Mutation, Scalp Dermatoses congenital
- Abstract
Background: Adams-Oliver syndrome (AOS) is a rare, inherited multi-systemic malformation syndrome characterized by a combination of aplasia cutis congenita and transverse terminal limb defects along with variable involvement of the central nervous system, eyes, and cardiovascular system. AOS can be inherited as both autosomal-dominant and recessive traits. Pathogenic variants in the DOCK6, ARHGAP31, EOGT, RBPJ, DLL4 , and NOTCH1 genes have been associated with AOS., Purpose: To report a novel homozygous variant in the DOCK6 gene associated with Adams-Oliver syndrome type 2., Materials and Methods: Case report., Results: We report a case of a 4-month-old male who presented with microcephaly, global developmental delay, truncal hypotonia, and limb reduction defects. Ophthalmic examination revealed bilateral nystagmus and retinal detachment with mild cataractous changes in addition to retrolental plaque in the left eye. Next generation sequencing analysis identified a novel homozygous frameshift likely pathogenic variant (c.1269_1285dup (p.Arg429Glnfs*32)) in the DOCK6 gene. The constellation of the clinical findings and the genetic mutation were consistent with a diagnosis of AOS type 2., Conclusion: The discovery of this new likely pathogenic variant enriches the genotypic spectrum of DOCK6 gene and contributes to genetic diagnosis and counseling of families with AOS. Neurologic and ocular findings appear to be consistent with AOS type 2 for which multidisciplinary clinical evaluation is crucial.
- Published
- 2020
- Full Text
- View/download PDF
46. Dermatoscopic Evaluation of Central Centrifugal Cicatricial Alopecia Beyond the Vertex Scalp.
- Author
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Felix K, De Souza B, Portilla N, Hogue L, Ahn CS, Sangueza O, and McMichael AJ
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Middle Aged, Scalp Dermatoses pathology, Alopecia diagnostic imaging, Alopecia pathology, Dermoscopy, Scalp diagnostic imaging, Scalp pathology, Scalp Dermatoses diagnostic imaging
- Published
- 2020
- Full Text
- View/download PDF
47. Alopecia areata and frontal fibrosing alopecia: dimorphism by concurrence.
- Author
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McSweeney SM, Stefanato CM, Fenton DA, McGrath JA, and Tziotzios C
- Subjects
- Administration, Topical, Adrenal Cortex Hormones administration & dosage, Adrenal Cortex Hormones therapeutic use, Aged, Alopecia Areata complications, Alopecia Areata drug therapy, Female, Fibrosis pathology, Humans, Lichen Planus complications, Lichen Planus drug therapy, Scalp Dermatoses complications, Treatment Outcome, Alopecia Areata pathology, Hair Follicle pathology, Lichen Planus pathology, Scalp Dermatoses pathology
- Published
- 2020
- Full Text
- View/download PDF
48. Erythematous plaque on the scalp with alopecia.
- Author
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Hu YQ, Yao XY, Zhou C, Zhang JZ, and Zhao Y
- Subjects
- Adult, Alopecia pathology, Erythema diagnosis, Erythema pathology, Female, Folliculitis pathology, Humans, Scalp Dermatoses pathology, Alopecia diagnosis, Folliculitis diagnosis, Scalp Dermatoses diagnosis
- Published
- 2020
- Full Text
- View/download PDF
49. Asymptomatic plaque on the scalp.
- Author
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García-Souto F, Coronel-Pérez IM, Sánchez-Santos Y, and Escudero-Ordoñez J
- Subjects
- Biopsy, Dermoscopy, Humans, Male, Middle Aged, Nevus pathology, Scalp Dermatoses pathology, Skin Neoplasms pathology, Nevus diagnosis, Scalp Dermatoses diagnosis, Skin Neoplasms diagnosis
- Published
- 2020
- Full Text
- View/download PDF
50. Nevus psiloliparus: Newly described histopathological features from transverse sections.
- Author
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Roman J, Taylor NA, Oza VS, and Kim RH
- Subjects
- Child, Female, Humans, Alopecia pathology, Lipomatosis pathology, Scalp Dermatoses pathology
- Abstract
Nevus psiloliparus is a rare fatty tissue nevus that is a marker for encephalocraniocutaneous lipomatosis, a neurocutaneous syndrome with ocular and central nervous system anomalies. Clinically, nevus psiloliparus is often described as a congenital alopecia and appears as an irregularly shaped, circumscribed area of alopecia on the scalp. Histopathology demonstrates a near-complete absence of mature hair follicles with preservation of arrector pili muscles and mature adipocytes within the dermis. The pathogenesis of nevus psiloliparus may be related to mosaic mutations in fibroblast growth factor receptor 1. Herein we report the histopathological features of a nevus psiloliparus in an 11-year-old girl diagnosed from transverse sections, which show "shadow" follicular units characterized by columns of loosely arranged collagen and a relative paucity of elastic fibers., (© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Published
- 2020
- Full Text
- View/download PDF
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