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Unlabelled: The main subject of the paper was to prove that beta-2-microglobulin (beta-2-m) exists in fluid taken from a thyroid gland cyst of the patients with non-toxic, nodular goitre with cysts and whether the confirmation of beta-2-m existence in fluid taken from a cyst may indicate the presence of autoimmunological process in thyroid glands. The research was carried out on a group of 36 patients operated on because of goitre. Patients with the thyroid cancer were except. The operations were carried out in the General Surgery Department of Hospital 1 in Sosnowiec from 1994 to 1999. The group of patients consisted of women aged between 13 to 75 years old (average 43 +/- 13.8 years). TSH, FT4 serum concentration in this investigated group were normal. The paper presents the beta-2-m existence in fluid taken from a thyroid gland cyst. It was confirmed that there was no differences between beta-2-m serum concentration in operated patients and in healthy controls. In 50% of patients operated on with thyroid cysts high antibody antithyroid peroxidase (antiTPO) serum concentration and in fluid taken from cyst was confirmed and statistically higher beta-2-m concentration in cyst fluid than beta-2-m concentration in serum., Conclusions: The increased antiTPO concentration in serum and in a fluid taken from cyst and beta-2-m existence in cyst fluid point to the autoimmunological process taking place in half of the patients with thyroid cysts.

Objectives: The aim of the study was the assessment of iodine turnover in healthy pregnant women supplemented by microelement and vitamin preparation Materna., Methods: To assess iodine supplementation, a modified PAAM method was used for measurement of iodine concentration in morning urine., Materials: 50 pregnant healthy women were tested for Materna supplementation. Urine iodine concentration was measured starting from the I trimester of pregnancy and then after 1, 2 and 3 months of Materna administration., Results: It has been found, that 3 months of supplementation with Materna reduces iodine deficiency in 83% of primiparas, while in the same time urine iodine concentration was normal in only 30% of women in their third and next pregnancy., Conclusion: In our opinion iodine urine concentration should be assessed in all multiparas using Materna after 1 month of supplementation in order to correct individual iodine supplementation doses.

This paper estimates the excretory kidneys activity in women with pregnancy complicated by EPH-gestosis and in women with a physiological pregnancy by denoting albuminuria, beta-2-microglobulinuria and beta-2-microglobulin in blood serum. It was claimed that the excretion of albumins with urine increases considerably in women with a pregnancy complicated by EPH-gestosis before the delivery in comparison with women with a pregnancy of a physiological course. The increase of albumins excretion with urine in a labour in two groups of tested pregnant women was also noticed. However, the increase in excretion of albumins with urine during delivery was much bigger in the group of women with pregnancy complicated by EPH-gestosis in comparison to the group of women with a physiological course of pregnancy. The albumins size before delivery as well as during the next 48 hours after the delivery did not differ statistically in both groups of tested women. Beta-2-microglobulin concentration in blood serum was bigger in the group of pregnant women with EPH-gestosis than women with a physiological pregnancy during the whole period of research. Bigger excretion of beta-2-microglobulin with urine was noticed among women with pregnancy complicated by EPH-gestosis before delivery, during delivery and during the next 48 hours after the delivery in relation to the group of women with a physiological pregnancy.