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Supplemental material, sj-pdf-2-wso-10.1177_17474930211069859 for Thrombectomy in basilar artery occlusion by Peter Sommer, Sebastian Scharer, Alexandra Posekany, Wolfgang Serles, Martha Marko, Agnes Langer, Elisabeth Fertl, Marek Sykora, Wilfried Lang, Sebastian Dafert, Fiona Seiringer, Stefan Kiechl, Michael Knoflach and Stefan Greisenegger in International Journal of Stroke

Supplemental material, sj-pdf-1-wso-10.1177_17474930211069859 for Thrombectomy in basilar artery occlusion by Peter Sommer, Sebastian Scharer, Alexandra Posekany, Wolfgang Serles, Martha Marko, Agnes Langer, Elisabeth Fertl, Marek Sykora, Wilfried Lang, Sebastian Dafert, Fiona Seiringer, Stefan Kiechl, Michael Knoflach and Stefan Greisenegger in International Journal of Stroke

Introduction:There is limited evidence whether mechanical thrombectomy (TE) is beneficial for patients with basilar artery occlusion (BAO). Previous studies have shown that intraarterial lysis +/- endovascular treatment may not be superior to intravenous thrombolysis (IVT). Our aim was to analyze rates of recanalization after TE in BAO and functional outcome after 3 months compared to proximal intracranial occlusion of the anterior circulation (ACS).Methods:The Austrian Endostroke Registry is part of the Austrian Stroke Unit Registry. We analyzed data of all patients enrolled to the Austrian Endostroke Registry with acute ischemic stroke caused by occlusion of intracranial artery. Recanalization rates were classified according to the Thrombolysis in Cerebral Infarction Scale (TICI) and the functional outcome measured by the modified Rankin Scale (mRS). Results:1869 patients underwent thrombectomy for ischemic stroke with proximal vessel occlusion from 2013-2017. Of those, 212 were treated for BAO and 1647 for ACS. Overall, baseline characteristics were comparable in patients with BAO and ACS, with exception of the median NIHSS at admission: BAO median NIHSS: 18 (25th percentile: 9; 75th percentile 28); ACS: 16 (12; 20); (table). Recanalization rates were similar (BAO: TICI 2b-3=77.1%, ACS=76%, respectively). Symptomatic intracranial bleedings rates were low in both groups (3.6% vs 6%). After 3 Months 36.4% of patients with BAO and 40% of patients with ACS had good functional outcome (mRS 0-2, figure). After adjusting for data imbalances with propensity score matching 424 patients (212 with BAO and 212 with ACS) were included into the analysis. In a multivariate proportional odds model for confounding factors we found no differences between BAO and ACS: Odds ratio 1.33, 95% Confidence Interval 0.94-1.89.Conclusion:Functional outcome after mechanical thrombectomy was comparable in BAO and ACS; however, mortality was substantially higher in BAO.