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8. Interstitielle Lungenerkrankung bei ulzerierenden Hautkalzinosen und Muskelbeteiligung – wie passt alles zusammen?

Author

Funke, Ann-Christin, Schnabel, Anja, Günther, Claudia, Hahn, Gabriele, Reinhard, Berner, and Brück, Normi

Subjects
Medicine and health
Abstract

Hintergrund: Die juvenile Dermatomyositis ist eine seltene Autoimmunerkrankung mit kutaner und muskulärer Inflammation, die nach wie vor häufig durch einen komplizierten Krankheitsverlauf gekennzeichnet ist. Pathogenetisch spielt die Aktivierung der Typ-I-Interferon-Signalwege eine zunehmende [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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11. Establishing core domain sets for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO): A report from the OMERACT 2020 special interest group

Author

Oliver, Melissa, primary, Jayatilleke, Aruni, additional, Wu, Eveline, additional, Nuruzzaman, Farzana, additional, Aguiar, Cassyanne, additional, Lenert, Aleksander, additional, Romano, Micol, additional, Simonini, Gabriele, additional, Shah, Samir, additional, Hollander, Matthew, additional, Alsaleem, Alhanouf, additional, Fox, Emily, additional, Theos, Alexander, additional, Ramanan, Athimalaipet V, additional, Schnabel, Anja, additional, Lapidus, Sivia, additional, Tucker, Lori, additional, Onel, Karen, additional, Ozen, Seza, additional, Dedeoglu, Fatma, additional, Ferguson, Polly J, additional, Shea, Beverley, additional, Akikusa, Jonathan, additional, Hedrich, Christian, additional, Mease, Philip, additional, and Zhao, Yongdong, additional

Published
2021
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12. Additional file 1 of First-year follow-up of children with chronic nonbacterial osteomyelitis���an analysis of the German National Pediatric Rheumatologic Database from 2009 to 2018

Author

Reiser, Christiane, Klotsche, Jens, Hospach, Anton, Berendes, Rainer, Schnabel, Anja, Jansson, Annette F., Hufnagel, Markus, Gr��sch, Nadine, Niewerth, Martina, Minden, Kirsten, and Girschick, Hermann

Abstract

Additional file 1: Age distribution at disease onset (PPTX 38 kb)

Published
2021
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13. Additional file 2 of First-year follow-up of children with chronic nonbacterial osteomyelitis���an analysis of the German National Pediatric Rheumatologic Database from 2009 to 2018

Author

Reiser, Christiane, Klotsche, Jens, Hospach, Anton, Berendes, Rainer, Schnabel, Anja, Jansson, Annette F., Hufnagel, Markus, Gr��sch, Nadine, Niewerth, Martina, Minden, Kirsten, and Girschick, Hermann

Subjects
musculoskeletal diseases, skin and connective tissue diseases
Abstract

Additional file 2: NSAID and DMARD therapy in selected CNO cohorts. NPRD: National Pediatric Rheumatologic Database (PPTX 43 kb)

Published
2021
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15. Interferon signature guiding therapeutic decision making: ruxolitinib as first-line therapy for severe juvenile dermatomyositis?

Author

Heinen, André, primary, Schnabel, Anja, additional, Brück, Normi, additional, Smitka, Martin, additional, Wolf, Christine, additional, Lucas, Nadja , additional, Dollinger, Stefanie, additional, Hahn, Gabriele, additional, Günther, Claudia, additional, Berner, Reinhard, additional, Lee-Kirsch, Min Ae, additional, and Schuetz, Catharina, additional

Published
2020
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16. Course and outcome of chilblain‐like acral lesions during COVID‐19 pandemic.

Author

Blau, Kristin, Lehr, Sophia, Aschoff, Roland, Al Gburi, Suzan, Brück, Normi, Chapsa, Maria, Schnabel, Anja, Abraham, Susanne, Jöhrens, Korinna, Beissert, Stefan, and Günther, Claudia

Subjects
COVID-19 pandemic, COVID-19, SARS-CoV-2 Omicron variant, TYPE I interferons
Abstract

This correlated with a lower incidence of chilblain-like lesions and might explain the observed decrease in chilblain-like lesions since winter 2022. Dear Editor, Exposure to Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) with mild COVID-19 disease can be followed by post-COVID cutaneous inflammation with a spectrum ranging from vasculitis to acral chilblain lesions.[[1], [3]] We have shown that chilblain-like lesions are characterized by activation of the type I interferon (IFN) pathway indicated by expression of human myxovirus resistance protein 1 (MXA) and phosphorylated Janus kinase 1 (JAK1) in lesional skin.[5] To further understand the clinical course and pathogenesis of SARS-CoV-2 associated chilblain-like lesions we followed 25 patients presenting to our department with new chilblain lesions during 2 years of the pandemic (2020-2022; Figure 1a). Symptoms ranged from mild reddish pale infiltrated to severe bullous, sporadically necrotic skin lesions at feet (17 patients) and hands (five patients) or both (three patients; Figure 2a). [Extracted from the article]

Published
2023
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17. Intravenöses Methylprednisolon als effektive Therapie bei Kindern und Jugendlichen mit autoimmuner Uveitis im akuten Schub

Author

Schnabel, Anja, Unger, Elisabeth, Range, Ursula, Morbach, Henner, Leszczynska, Anna, Berner, Reinhard, Bau, Viktoria, and Hedrich, Christian

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Entzündliche Augenerkrankungen stellen weltweit eine wichtige Ursache für Erblindungen dar. Die autoimmune Uveitis birgt das Risiko für komplizierte Verläufe mit irreparablen Folgeschäden, so dass eine zeitnahe und adäquate immunsuppressive Therapie prognoseentscheidend[zum vollständigen Text gelangen Sie über die oben angegebene URL], 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019

18. Childhood Vasculitis

Author

Schnabel, Anja and Hedrich, Christian M.

Subjects
paediatric, classification, inflammation, purpura, Review, systemic disease, granulomatosis with polyangitis, kawasaki disease, Pediatrics, vasculitis
Abstract

The term vasculitis covers heterogeneous disorders that share the presence of inflammation of blood vessel walls. Immune cell infiltrates can vary significantly and involve granulocytes or mononuclear cells. Vasculitis can be a symptom of other underlying disorders or the underlying cause of organ specific or systemic disease. Classification of childhood vasculitis is based on clinic, the size of predominantly affected vessels, and the histopathology of inflammatory infiltrates. Timely and accurate diagnosis and (where necessary) treatment initiation determine disease progression and outcomes. In light of new developments and the identification of autoinflammatory conditions with vasculitis, new classification tools may be discussed.

Published
2019

19. Bridging bronchus - a rare cause of recurrent wheezy bronchitis

Author

Schnabel Anja, Glutig Katja, and Vogelberg Christian

Subjects
Congenital airway anomalies, Bronchial branching anomaly, Airway malformation, Pediatrics, RJ1-570
Abstract

Abstract Background Wheezing is a common symptom in infants and toddlers. Usually it occurs due to viral infection of the lower airways and no further diagnostic procedures are necessary. However in rare cases, other reasons such as anatomical malformation have to be considered. Case presentation We report about an infant with recurrent episodes of wheezy bronchitis, which persisted despite adequate therapy. Bronchoscopy and computed tomography of the lung with three-dimensional reconstruction revealed a rare bronchial branching anomaly - the so called “bridging bronchus”. In contrast to previous case reports, this infant showed no additional malformations, which seems to be important for the prognosis. Conclusion To the best of our knowledge this is the first report about a patient with a bridging bronchus in its “original form” without associated anomalies of the trachea-bronchial system or other organs.

Published
2012
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20. Bleiben in Breslau

Author

Schnabel, Anja

Subjects
Historisches Institut, ddc:943
Abstract

Der Breslauer Jude Willy Cohn musste nach der Machtübernahme der Nationalsozialisten erleben, wie die deutschen Juden in immer größerem Umfang entrechtet, ausgegrenzt und existenziell bedroht werden. Trotzdem kam eine Auswanderung aus Deutschland als seiner Heimat für ihn letztlich nicht in Betracht. Im Winter 1941 wurde Willy Cohn mit seiner Familie aus Breslau deportiert und von den Nationalsozialisten ermordet. Ausgehend von Cohns Entscheidung, in Breslau zu bleiben, betrachtet die Untersuchung das Bleiben als Aushandlungsprozess und macht so exemplarisch das Bleiben im NS-Deutschland als Akt der Selbstbehauptung sichtbar. Hierfür wurde der rund 10.000 Seiten umfassende Tagebuchnachlass Willy Cohns aus den Jahren zwischen 1899 und 1941 erstmals in seiner Gesamtheit systematisch gesichtet und ausgewertet.

Published
2018

23. Orbital inflammation and colitis in pediatric IgG4-related disease: A case report and review of the literature.

Author

Tille, Lissy, Schnabel, Anja, Laass, Martin W., Hahn, Gabriele, Taut, Heike, Leszczynska, Anna, Pablik, Jessica, Berner, Reinhard, Brück, Normi, and Hedrich, Christian M.

Subjects
*COLITIS, *LITERATURE reviews, *PLASMA cells, *WEIGHT loss, *MYCOPHENOLIC acid, *ISCHEMIC colitis
Abstract

IgG4-related disease (IgG4-RD) is an inflammatory disorder characterized by tumor-like swelling in one or more organs, elevated serum IgG4 levels, and histological alterations with infiltration of IgG4-positive plasma cells. IgG4-RD is rare and likely underdiagnosed in children. We report a case of a 16-year-old girl with IgG4-positive colitis that developed weeks after IgG4-related ophthalmic disease and discuss diagnosis and treatment in the context of the literature available. Since the pathophysiology of IgG4-RD is unknown, treatment options are empiric and, for the most part, untargeted. Systemic corticosteroid treatment is the basis of anti-inflammatory treatment in IgG4-RD and induced early remission in our patient. During corticosteroid taper, the patient developed weight loss and intestinal inflammation. Histopathological assessment of the intestinal walls confirmed IgG4-positive colitis. Immune-modulating treatment with non-biologic (e.g., methotrexate (MTX) and mycophenolate mofetil) or biologic (rituximab) disease-modifying antirheumatic drugs has been reported in treatment refractory or corticosteroid-dependent patients. The patient responded to treatment with anti-inflammatory therapy with food rich in TGF-β2 (modulen) and MTX. This is one of the first pediatric patients reported with IgG4-related colitis extending the phenotype of pediatric IgG4-RD. International collaboration to prospectively document clinical presentation and treatment responses may help to further establish the phenotype and treatment options and to raise awareness for IgG4-RD. [ABSTRACT FROM AUTHOR]

Published
2020
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26. Vergleich der chronisch nicht-bakteriellen (CNO) und bakteriellen Osteomyelitis im Kindesalter

Author

Schnabel, Anja, Range, Ursula, Hahn, Gabriele, Berner, Reinhard, and Hedrich, Christian Michael

Subjects
ddc: 610, Infektion, Osteomyelitis, bakterielle Osteomyelitis, 610 Medical sciences, Medicine, CRMO, CNO, nicht-bakterielle Osteomyelitis
Abstract

Einleitung: Historisch betrachtet, wurde die Osteomyelitis als infektiöses Krankheitsbild eingeordnet. Studien der letzten Jahre identifizieren auto-inflammatorische Mechanismen als ursächlich für einen wesentlichen Anteil der kindlichen Osteomyelitiden. Ziel der Studie war es klinische[zum vollständigen Text gelangen Sie über die oben angegebene URL], 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2016

27. Therapieansprechen bei Kindern mit chronisch nicht-bakterieller Osteomyelitis (CNO)

Author

Schnabel, Anja, Range, Ursula, Berner, Reinhard, and Hedrich, Christian Michael

Subjects
ddc: 610, Rezidiv, Osteomyelitis, Langzeitprognose, 610 Medical sciences, Medicine, CRMO, Therapie, CNO, nicht-bakterielle Osteomyelitis
Abstract

Einleitung: Die chronisch nicht-bakteriellen Osteomyelitis (CNO) ist die wahrscheinlich häufigste auto-inflammatorische Erkrankung des Kindesalters. Sie umfasst ein weites Spektrum mit milden, zeitlich limitierten Erkrankungen auf der einen Seite und prolongierten, rekurrierenden Verläufen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2016
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29. Interferon signature guiding therapeutic decision making: ruxolitinib as first-line therapy for severe juvenile dermatomyositis?

Author

Heinen, André, Schnabel, Anja, Brück, Normi, Smitka, Martin, Wolf, Christine, Lucas, Nadja, Dollinger, Stefanie, Hahn, Gabriele, Günther, Claudia, Berner, Reinhard, Lee-Kirsch, Min Ae, and Schuetz, Catharina

Subjects
*AUTOANTIBODIES, *DERMATOMYOSITIS, *MAGNETIC resonance imaging, *CREATINE kinase, *JANUS kinases, *LEG, *INTERFERONS, *SEVERITY of illness index, *TREATMENT effectiveness, *MUSCLE strength, *NEUROTRANSMITTER uptake inhibitors, *MYOGLOBIN, *BLOOD coagulation factors, *IMMUNOSUPPRESSIVE agents, *ADOLESCENCE
Abstract

The article presents a case report of a 14-year-old boy with anti-nuclear matrix protein-2 (NXP2) positive juvenile dermatomyositis (JDM). Examinations showed pronounced symmetrical muscular weakness leaving him bedridden with elevated levels of creatinine kinase activity, myoglobin, and von-Willebrand antigen among other conditions. Treatment with ruxolitinib resulted in the patient's clinical improvement, normalization of inflammatory markers and increased mobility.

Published
2021
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30. Untersuchungen zur Funktion enterischer Gliazellen bei der Vermittlung der angeborenen Immunantwort

Author

Schnabel, Anja, Engelmann, Lothar, Pierer, Matthias, Wagner, Ulf, Emmrich, Frank, and Universität Leipzig

Subjects
ddc:610, Enterische Glia, angeborene Immunantwort, Toll-like-Rezeptor, NF-kB Signalweg, enteric glia, innate immunity, Toll-like-receptor, NF-kB signaling
Abstract

Die Gliazellen des enterischen Nervensystems galten lange Zeit lediglich als Packmaterial der Neuronen. Erst in den letzten Jahren rückte dieser Zelltyp in das Interesse der Forschung, weil mehrere Studien eine Schlüsselrolle bei der Erhaltung der Darmwandintegrität postulierten. Da bisher wenig über die immunphysiologischen Eigenschaften der enterischen Gliazellen bekannt war, wurde in dieser Arbeit deren Bedeutung bei der angeborenen intestinalen Immunantwort untersucht. Hierfür wurden Primärkulturen von enterischen Gliazellen eingesetzt, welche aus dem Plexus myentericus adulter Ratten stammten. Es wurde erstmalig nachgewiesen, dass enterische Gliazellen über Toll like und NOD-Rezeptoren (TLR 2, TLR 4, TLR 6, TLR 7, TLR 9, NOD 1, NOD 2) pathogene bakterielle Muster (PAMPs) erkennen. Dabei zeigte sich, dass eine enge Vernetzung zwischen den Toll-like-Rezeptoren besteht. Einerseits findet eine Liganden-spezifische Regulierung der Toll-like-Rezeptoren statt, anderseits beeinflussen TLR spezifische Liganden die mRNA-Expression weiterer Toll-like-Rezeptoren. In der Analyse der intrazellulären Signalweiterleitung konnte die Existenz verschiedener Adaptor- und Interaktionsmoleküle wie RICK und Myd88 sowie der IKK / NF κB Signalweg mit Degradierung von IκB α nach Aktivierung durch LPS belegt werden. Aktivierte enterische Gliazellen sind eine Quelle für pro- und anti-inflammatorische Interleukine (IL-1α, IL 1β, IL 6, IL-10, IL-12), TNF α und Chemokine (Ccl-2, Cxcl-9, Cxcl-10). Sie können somit weitere immunkompetente Zellen rekrutieren und agieren vermutlich als Schnittstelle zwischen der angeborenen und erworbenen Immunantwort. Die Ergebnisse dieser Arbeit implizieren, dass es sich bei enterischen Gliazellen um einen zusätzlichen immunregulatorischen Zelltyp im Darm handelt, welcher aktiv bei der angeborenen Immunabwehr mitwirkt. Neben pro inflammatorischen Eigenschaften tragen enterische Gliazellen auch zur Darmprotektion während Entzündungsprozessen bei. Daraus ergibt sich eine komplexe Funktionalität der enterischen Gliazellen bei der immunologischen Homöostase im Darm.

Published
2014

33. Untersuchungen zur Funktion enterischer Gliazellen bei der Vermittlung der angeborenen Immunantwort

Author

Pierer, Matthias, Wagner, Ulf, Emmrich, Frank, Universität Leipzig, Schnabel, Anja, Pierer, Matthias, Wagner, Ulf, Emmrich, Frank, Universität Leipzig, and Schnabel, Anja

Abstract

Die Gliazellen des enterischen Nervensystems galten lange Zeit lediglich als Packmaterial der Neuronen. Erst in den letzten Jahren rückte dieser Zelltyp in das Interesse der Forschung, weil mehrere Studien eine Schlüsselrolle bei der Erhaltung der Darmwandintegrität postulierten. Da bisher wenig über die immunphysiologischen Eigenschaften der enterischen Gliazellen bekannt war, wurde in dieser Arbeit deren Bedeutung bei der angeborenen intestinalen Immunantwort untersucht. Hierfür wurden Primärkulturen von enterischen Gliazellen eingesetzt, welche aus dem Plexus myentericus adulter Ratten stammten. Es wurde erstmalig nachgewiesen, dass enterische Gliazellen über Toll like und NOD-Rezeptoren (TLR 2, TLR 4, TLR 6, TLR 7, TLR 9, NOD 1, NOD 2) pathogene bakterielle Muster (PAMPs) erkennen. Dabei zeigte sich, dass eine enge Vernetzung zwischen den Toll-like-Rezeptoren besteht. Einerseits findet eine Liganden-spezifische Regulierung der Toll-like-Rezeptoren statt, anderseits beeinflussen TLR spezifische Liganden die mRNA-Expression weiterer Toll-like-Rezeptoren. In der Analyse der intrazellulären Signalweiterleitung konnte die Existenz verschiedener Adaptor- und Interaktionsmoleküle wie RICK und Myd88 sowie der IKK / NF κB Signalweg mit Degradierung von IκB α nach Aktivierung durch LPS belegt werden. Aktivierte enterische Gliazellen sind eine Quelle für pro- und anti-inflammatorische Interleukine (IL-1α, IL 1β, IL 6, IL-10, IL-12), TNF α und Chemokine (Ccl-2, Cxcl-9, Cxcl-10). Sie können somit weitere immunkompetente Zellen rekrutieren und agieren vermutlich als Schnittstelle zwischen der angeborenen und erworbenen Immunantwort. Die Ergebnisse dieser Arbeit implizieren, dass es sich bei enterischen Gliazellen um einen zusätzlichen immunregulatorischen Zelltyp im Darm handelt, welcher aktiv bei der angeborenen Immunabwehr mitwirkt. Neben pro inflammatorischen Eigenschaften tragen enterische Gliazellen auch zur Darmprotektion während Entzündungsprozessen bei. Daraus ergibt

Published
2014

34. Untersuchungen zur Funktion enterischer Gliazellen bei der Vermittlung der angeborenen Immunantwort

Author

Engelmann, Lothar, Pierer, Matthias, Wagner, Ulf, Emmrich, Frank, Universität Leipzig, Schnabel, Anja, Engelmann, Lothar, Pierer, Matthias, Wagner, Ulf, Emmrich, Frank, Universität Leipzig, and Schnabel, Anja

Abstract

Die Gliazellen des enterischen Nervensystems galten lange Zeit lediglich als Packmaterial der Neuronen. Erst in den letzten Jahren rückte dieser Zelltyp in das Interesse der Forschung, weil mehrere Studien eine Schlüsselrolle bei der Erhaltung der Darmwandintegrität postulierten. Da bisher wenig über die immunphysiologischen Eigenschaften der enterischen Gliazellen bekannt war, wurde in dieser Arbeit deren Bedeutung bei der angeborenen intestinalen Immunantwort untersucht. Hierfür wurden Primärkulturen von enterischen Gliazellen eingesetzt, welche aus dem Plexus myentericus adulter Ratten stammten. Es wurde erstmalig nachgewiesen, dass enterische Gliazellen über Toll like und NOD-Rezeptoren (TLR 2, TLR 4, TLR 6, TLR 7, TLR 9, NOD 1, NOD 2) pathogene bakterielle Muster (PAMPs) erkennen. Dabei zeigte sich, dass eine enge Vernetzung zwischen den Toll-like-Rezeptoren besteht. Einerseits findet eine Liganden-spezifische Regulierung der Toll-like-Rezeptoren statt, anderseits beeinflussen TLR spezifische Liganden die mRNA-Expression weiterer Toll-like-Rezeptoren. In der Analyse der intrazellulären Signalweiterleitung konnte die Existenz verschiedener Adaptor- und Interaktionsmoleküle wie RICK und Myd88 sowie der IKK / NF κB Signalweg mit Degradierung von IκB α nach Aktivierung durch LPS belegt werden. Aktivierte enterische Gliazellen sind eine Quelle für pro- und anti-inflammatorische Interleukine (IL-1α, IL 1β, IL 6, IL-10, IL-12), TNF α und Chemokine (Ccl-2, Cxcl-9, Cxcl-10). Sie können somit weitere immunkompetente Zellen rekrutieren und agieren vermutlich als Schnittstelle zwischen der angeborenen und erworbenen Immunantwort. Die Ergebnisse dieser Arbeit implizieren, dass es sich bei enterischen Gliazellen um einen zusätzlichen immunregulatorischen Zelltyp im Darm handelt, welcher aktiv bei der angeborenen Immunabwehr mitwirkt. Neben pro inflammatorischen Eigenschaften tragen enterische Gliazellen auch zur Darmprotektion während Entzündungsprozessen bei. Daraus ergibt

Published
2014

35. Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting: Toronto, Canada. 14-17 April 2016

Author

Fotis, Lampros, Shaikh, Nur, Baszis, Kevin, French, Anthony, Tarr, Phillip, Grevich, Sriharsha, Lee, Peggy, Ringold, Sarah, Leroux, Brian, Leahey, Hannah, Yuasa, Megan, Foster, Jessica, Sokolove, Jeremy, Lahey, Lauren, Robinson, William, Newsom, Joshua, Stevens, Anne, Karasawa, Rie, Tamaki, Mayumi, Tanaka, Megumi, Sato, Toshiko, Yudoh, Kazuo, Jarvis, James N., Moncrieffe, Halima, Bennett, Mark F., Tsoras, Monica, Luyrink, Lorie, Xu, Huan, Prahalad, Sampath, Morris, Paula, Dare, Jason, Nigrovic, Peter A., Rosenkranz, Margalit, Becker, Mara, O’Neil, Kathleen M., Griffin, Thomas, Lovell, Daniel J., Grom, Alexei A., Medvedovic, Mario, Thompson, Susan D., Zhu, Lisha, Jiang, Kaiyu, Wong, Laiping, Buck, Michael J, Chen, Yanmin, Brungs, Laura, Liu, Tao, Wang, Ting, Jarvis, James N, Alsaeid, Khaled, Alfailakawi, Jasim, Alenezi, Hamid, Alsaeed, Hazim, Beukelman, Tim, Natter, Marc, Ilowite, Norm, Mieszkalski, Kelly, Burrell, Grendel, Best, Brian, Bristow, Helen, Carr, Shannon, Dennos, Anne, Kaufmann, Rachel, Kimura, Yukiko, Schanberg, Laura, Blier, Peter R., Boneparth, Alexis, Wenderfer, Scott E., Moorthy, L. Nandini, Radhakrishna, Suhas M., Sagcal-Gironella, Anna Carmela P., von Scheven, Emily, Gedik, Kader Cetin, Siddique, Salma, Aguiar, Cassyanne L., Erkan, Doruk, Cohen, Ezra, Lee, Yvonne, Dossett, Michelle, Mehta, Darshan, Davis, Roger, Gilbert, Mileka, Goilav, Beatrice, Meidan, Esra, Hsu, Joyce, Chua, Anabelle, Ardoin, Stacy, Von Scheven, Emily, Ruth, Natasha M., Hui-Yuen, Joyce, Bermudez, Liza, Cook, Ashlea, Imundo, Lisa, Starr, Amy, Eichenfield, Andrew, Askanase, Anca, Janow, Ginger, Schanberg, Laura E., Setoguchi, Soko, Hasselblad, Victor, Mellins, Elizabeth D., Schneider, Rayfel, Beukelman, Timothy, Morgan, Esi, Graham, T. Brent, Ibarra, Maria, Ruas, Yonit Sterba, Klein-Gitelman, Marisa, Onel, Karen, Punaro, Marilynn, Toib, Dana, Van Mater, Heather, Weiss, Jennifer E., Weiss, Pamela F., Kwok, Timothy S. H., Bisaillon, Jacinthe, Smith, Christine, Brosseau, Lucie, Stinson, Jennifer, Huber, Adam M., Duffy, Ciaran M., April, Karine Toupin, Lewandowski, Laura B., Scott, Christiaan, Li, Suzanne C., Torok, Kathryn S., Rabinovich, C. Egla, Hong, Sandy D., Becker, Mara L, Dedeoglu, Fatma, Ibarra, Maria F., Ferguson, Polly J, Fuhbrigge, Rob C., Stewart, Katie G., Pope, Elena, Laxer, Ronald M., Mason, Thomas G., Higgins, Gloria C., Li, Xiaohu, Punaro, Marilynn G., Tomlinson, George, Pullenayegum, Eleanor, Matelski, John, Feldman, Brian M., Manthiram, Kalpana, Correa, Hernan, Edwards, Kathryn, Oberle, Edward J., Bayer, Michelle, Co, Dominic O., Baris, Hatice Ezgi, Chiu, Yvonne, Huber, Adam, Kim, Susan, Orandi, Amir B., Baszis, Kevin W., Dharnidharka, Vikas, Hoeltzel, Mark F., Reed, Ann, Goh, Y. Ingrid, Schnabel, Anja, Range, Ursula, Hahn, Gabriele, Siepmann, Timo, Berner, Reinhard, Hedrich, Christian Michael, Stevens, Brandi, Li, Suzanne, Hershey, Nicole, Curran, Megan, Higgins, Gloria, Moore, Katharine, Rabinovich, Egla, Stevens, Anne M., Connelly, Mark, Luca, Nadia, Spiegel, Lynn, Tsimicalis, Argerie, Luca, Stephanie, Tajuddin, Naweed, Berard, Roberta, Barsalou, Julia, Campillo, Sarah, Dancey, Paul, Duffy, Ciaran, Feldman, Brian, Johnson, Nicole, McGrath, Patrick, Shiff, Natalie, Tse, Shirley, Tucker, Lori, Victor, Charles, Lalloo, Chitra, Harris, Lauren, Cafazzo, Joseph, Laxer, Ronald, Bullock, Danielle R., Vehe, Richard K., Zhang, Lei, Correll, Colleen K., Ganguli, Suhas, Shenberger, Max, Korumilli, Ritesh, Gottlieb, Beth, Rodriguez, Martha, de Ranieri, Deirdre, Wagner-Weiner, Linda, Tesher, Melissa, Wojcicki, Elizabeth Roth, Maletta, Kristyn L., Malloy, Marsha, Thomson, Sarah, Olson, Judyann C., Sule, Sangeeta, Rubinstein, Tamar B., Okamura, Daryl M., Chua, Annabelle, Greenbaum, Laurence A., Lane, Jerome C., Ardoin, Stacy P., Woo, Jennifer M. P., Malloy, Marsha M., Jegers, James A., Hahn, Dustin J., Hintermeyer, Mary K., Martinetti, Stacey M., Heckel, Gretchen R., and Roth-Wojcicki, Elizabeth L.

Abstract

Table of Contents P1 Serologic evidence of gut-driven systemic inflammation in juvenile idiopathic arthritis Lampros Fotis, Nur Shaikh, Kevin Baszis, Anthony French, Phillip Tarr P2 Oral health and anti-citrullinated peptide antibodies (ACPA) in juvenile idiopathic arthritis Sriharsha Grevich, Peggy Lee, Sarah Ringold, Brian Leroux, Hannah Leahey, Megan Yuasa, Jessica Foster, Jeremy Sokolove, Lauren Lahey, William Robinson, Joshua Newsom, Anne Stevens P3 Novel autoantigens for endothelial cell antibodies in pediatric rheumatic diseases identified by proteomics Rie Karasawa, Mayumi Tamaki, Megumi Tanaka, Toshiko Sato, Kazuo Yudoh, James N. Jarvis P4 Transcriptional profiling reveals monocyte signature associated with JIA patient poor response to methotrexate Halima Moncrieffe, Mark F. Bennett, Monica Tsoras, Lorie Luyrink, Huan Xu, Sampath Prahalad, Paula Morris, Jason Dare, Peter A. Nigrovic, Margalit Rosenkranz, Mara Becker, Kathleen M. O’Neil, Thomas Griffin, Daniel J. Lovell, Alexei A. Grom, Mario Medvedovic, Susan D. Thompson P5 A multi-dimensional genomic map for polyarticular juvenile idiopathic arthritis Lisha Zhu, Kaiyu Jiang, Laiping Wong, Michael J Buck, Yanmin Chen, Halima Moncrieffe, Laura Brungs, Tao Liu, Ting Wang, James N Jarvis P6 Tocilizumab for treatment of children with refractory JIA Khaled Alsaeid, Jasim Alfailakawi, Hamid Alenezi, Hazim Alsaeed P7 Clinical characteristics of the initial patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry Tim Beukelman, Marc Natter, Norm Ilowite, Kelly Mieszkalski, Grendel Burrell, Brian Best, Helen Bristow, Shannon Carr, Anne Dennos, Rachel Kaufmann, Yukiko Kimura, Laura Schanberg P8 Comparative performance of small and large clinical centers in a comprehensive pediatric rheumatology disease registry Peter R Blier P9 Clinical characteristics of children with membranous lupus nephritis: The Childhood Arthritis and Rheumatology Research Alliance Legacy Registry Alexis Boneparth, Scott E. Wenderfer, L. Nandini Moorthy, Suhas M. Radhakrishna, Anna Carmela P. Sagcal-Gironella, Emily von Scheven P10 Rituximab use in pediatric lupus anticoagulant hypoprothrombinemia syndrome - a two center experience Kader Cetin Gedik, Salma Siddique, Cassyanne L. Aguiar, Doruk Erkan P11 Predictors of complementary and alternative medicine use and response in children with musculoskeletal conditions Ezra Cohen, Yvonne Lee, Michelle Dossett, Darshan Mehta, Roger Davis P12 Comparison of pediatric rheumatology and nephrology survey results for the treatment of refractory proliferative lupus nephritis and renal flare in juvenile SLE Mileka Gilbert, Beatrice Goilav, Esra Meidan, Joyce Hsu, Alexis Boneparth, Anabelle Chua, Stacy Ardoin, Scott E. Wenderfer, Emily Von Scheven, Natasha M. Ruth P13 Transitioning lupus patients from pediatric to adult rheumatology Joyce Hui-Yuen, Kader Cetin Gedik, Liza Bermudez, Ashlea Cook, Lisa Imundo, Amy Starr, Andrew Eichenfield, Anca Askanase P14 The systemic juvenile idiopathic arthritis cohort of the Childhood Arthritis & Rheumatology Research Alliance Registry Ginger Janow, Laura E. Schanberg, Soko Setoguchi, Victor Hasselblad, Elizabeth D. Mellins, Rayfel Schneider, Yukiko Kimura, The CARRA Legacy Registry Investigators P15 Results of the pilot study of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans for new-onset systemic juvenile idiopathic arthritis Yukiko Kimura, Sriharsha Grevich, Timothy Beukelman, Esi Morgan, T Brent Graham, Maria Ibarra, Yonit Sterba Ruas, Marisa Klein-Gitelman, Karen Onel, Sampath Prahalad, Marilynn Punaro, Sarah Ringold, Dana Toib, Heather Van Mater, Jennifer E. Weiss, Pamela F. Weiss, Kelly Mieszkalski, Laura E. Schanberg P16 A systemic review of pain relief modalities in juvenile idiopathic arthritis: First step in developing a novel decision support intervention Timothy S. H. Kwok, Jacinthe Bisaillon, Christine Smith, Lucie Brosseau, Jennifer Stinson, Adam M. Huber, Ciaran M. Duffy, Karine Toupin April P17 Barriers and facilitators to care retention for pediatric systemic lupus erythematous patients in South Africa: A qualitative study Laura B Lewandowski, Christiaan Scott P18 Evaluating the feasibility of conducting comparative effectiveness studies in juvenile Localized Scleroderma (jLS) Suzanne C. Li, Kathryn S. Torok, C. Egla Rabinovich, Sandy D. Hong, Mara L Becker, Fatma Dedeoglu, Maria F. Ibarra, Polly J Ferguson, Rob C. Fuhbrigge, Katie G. Stewart, Elena Pope, Ronald M. Laxer, Thomas G. Mason, Gloria C. Higgins, Xiaohu Li, Marilynn G. Punaro, George Tomlinson, Eleanor Pullenayegum, John Matelski, Laura Schanberg, Brian M. Feldman P19 Tonsillar histology in patients with periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome Kalpana Manthiram, Hernan Correa, Kathryn Edwards P20 Clinical course of juvenile dermatomyositis presenting as skin predominant disease Edward J. Oberle, Michelle Bayer, Dominic O. Co, Hatice Ezgi Baris, Yvonne Chiu, Adam Huber, Susan Kim P21 A Survey of musculoskeletal ultrasound practices of pediatric rheumatologists in North America Edward J Oberle, Timothy Beukelman P22 Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: A survey of pediatric rheumatologists by the Childhood Arthritis and Rheumatology Research Alliance Amir B. Orandi, Kevin W. Baszis, Vikas Dharnidharka, Mark F. Hoeltzel, for the CARRA JDM Committee P23 CARRA dermatomyositis CTP pilot study Ann Reed, Adam Huber, George Tomlinson, Eleanor Pullenayegum, John Matelski, Y. Ingrid Goh, Laura Schanberg, Brian M. Feldman P24 Unexpectedly high incidences and prolonged disease activity in children with chronic non-bacterial osteomyelitis (CNO) as compared to bacterial osteomyelitis Anja Schnabel, Ursula Range, Gabriele Hahn, Timo Siepmann, Reinhard Berner, Christian Michael Hedrich P25 Juvenile systemic sclerosis cohort within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry: Follow up characteristics Brandi Stevens, Kathryn S. Torok, Suzanne Li, Nicole Hershey, Megan Curran, Gloria Higgins, Katharine Moore, Egla Rabinovich, Anne M. Stevens, for the CARRA Registry Investigators P26 Development and usability testing of an iPad and desktop psycho-educational game for children with Juvenile Idiopathic Arthritis and their parents Jennifer Stinson, Mark Connelly, Adam Huber, Nadia Luca, Lynn Spiegel, Argerie Tsimicalis, Stephanie Luca, Naweed Tajuddin, Roberta Berard, Julia Barsalou, Sarah Campillo, Paul Dancey, Ciaran Duffy, Brian Feldman, Nicole Johnson, Patrick McGrath, Natalie Shiff, Shirley Tse, Lori Tucker, Charles Victor P27 iCanCopeTM: User-centred design and development of a smartphone app to support self-management for youth with arthritis pain Jennifer Stinson, Chitra Lalloo, Lauren Harris, Joseph Cafazzo, Lynn Spiegel, Brian Feldman, Nadia Luca, Ronald Laxer P28 Accessing pediatric rheumatology care: Despite barriers, few parents prefer telemedicine Danielle R. Bullock, Richard K. Vehe, Lei Zhang, Colleen K. Correll1 P29 Exploration of factors contributing to time to achieve clinically inactive disease (CID) in juvenile idiopathic arthritis (JIA): A preliminary report Suhas Ganguli, Max Shenberger, Ritesh Korumilli, Beth Gottlieb P30 Pediatric rheumatology referral patterns: Presenting complaints of new patients at a large, urban academic center Martha Rodriguez, Deirdre de Ranieri, Karen Onel, Linda Wagner-Weiner, Melissa Tesher P31 Quality improvement (QI) initiatives in childhood systemic lupus erythematosus (cSLE) Elizabeth Roth Wojcicki, Kristyn L. Maletta, Dominic O. Co, Marsha Malloy, Sarah Thomson, Judyann C. Olson P32 Proliferative lupus nephritis in juvenile SLE: Support from the pediatric nephrology community for the definitions of responsiveness and flare in the 2012 consensus treatment plans Scott E. Wenderfer, Mileka Gilbert, Joyce Hsu, Sangeeta Sule, Tamar B. Rubinstein, Beatrice Goilav, Daryl M. Okamura, Annabelle Chua, Laurence A. Greenbaum, Jerome C. Lane, Emily von Scheven, Stacy P. Ardoin, Natasha M. Ruth P33 The steroid taper app: Making of a mobile app Jennifer M. P. Woo, Marsha M. Malloy, James A. Jegers, Dustin J. Hahn, Mary K. Hintermeyer, Stacey M. Martinetti, Gretchen R. Heckel, Elizabeth L. Roth-Wojcicki, Dominic O. Co

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2016
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36. Comparison of Clinicopathologic and Imaging Features Between Chronic Nonbacterial Osteomyelitis and Its Mimickers: A Multi-national 450 Case-Control Study

Author

Zhao, Yongdong, Naden, Raymond, Oliver, Melissa, Wang, Zhaoyi, Wu, Eveline, Aguiar, Cassyanne, Akikusa, Jonathan, Basaran, Ozge, Cain, Kevin, Capponi, Martina, Donaldson, Nathan, Fox, Emily, Insalaco, Antonella, Jansson, Annette, Akca, Ummusen Kaya, Lee, Tzielan, Marrani, Edoardo, Mahmood, Kamran, Murray, Elizabeth, Nuruzzaman, Farzana, Onel, Karen, Pardeo, Manuela, Potts, Lauren, Rogers, Nathan, Schnabel, Anja, Gabriele Simonini, Soep, Jennifer, Stern, Sara, Theos, Alexander, Zhang, Yujuan, Ferguson, Polly, Hedrich, Christian, Dedeoglu, Fatma, Girschick, Hermann, Laxer, Ronald, and Ozen, Seza

37. Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting

Author

Fotis, Lampros, Shaikh, Nur, Baszis, Kevin, French, Anthony, Tarr, Phillip, Grevich, Sriharsha, Lee, Peggy, Ringold, Sarah, Leroux, Brian, Leahey, Hannah, Yuasa, Megan, Foster, Jessica, Sokolove, Jeremy, Lahey, Lauren, Robinson, William, Newsom, Joshua, Stevens, Anne, Karasawa, Rie, Tamaki, Mayumi, Tanaka, Megumi, Sato, Toshiko, Yudoh, Kazuo, Jarvis, James N., Moncrieffe, Halima, Bennett, Mark F., Tsoras, Monica, Luyrink, Lorie, Xu, Huan, Prahalad, Sampath, Morris, Paula, Dare, Jason, Nigrovic, Peter A., Rosenkranz, Margalit, Becker, Mara, O’Neil, Kathleen M., Griffin, Thomas, Lovell, Daniel J., Grom, Alexei A., Medvedovic, Mario, Thompson, Susan D., Zhu, Lisha, Jiang, Kaiyu, Wong, Laiping, Buck, Michael J, Chen, Yanmin, Brungs, Laura, Liu, Tao, Wang, Ting, Jarvis, James N, Alsaeid, Khaled, Alfailakawi, Jasim, Alenezi, Hamid, Alsaeed, Hazim, Beukelman, Tim, Natter, Marc, Ilowite, Norm, Mieszkalski, Kelly, Burrell, Grendel, Best, Brian, Bristow, Helen, Carr, Shannon, Dennos, Anne, Kaufmann, Rachel, Kimura, Yukiko, Schanberg, Laura, Blier, Peter R., Boneparth, Alexis, Wenderfer, Scott E., Moorthy, L. Nandini, Radhakrishna, Suhas M., Sagcal-Gironella, Anna Carmela P., von Scheven, Emily, Gedik, Kader Cetin, Siddique, Salma, Aguiar, Cassyanne L., Erkan, Doruk, Cohen, Ezra, Lee, Yvonne, Dossett, Michelle, Mehta, Darshan, Davis, Roger, Gilbert, Mileka, Goilav, Beatrice, Meidan, Esra, Hsu, Joyce, Chua, Anabelle, Ardoin, Stacy, Von Scheven, Emily, Ruth, Natasha M., Hui-Yuen, Joyce, Bermudez, Liza, Cook, Ashlea, Imundo, Lisa, Starr, Amy, Eichenfield, Andrew, Askanase, Anca, Janow, Ginger, Schanberg, Laura E., Setoguchi, Soko, Hasselblad, Victor, Mellins, Elizabeth D., Schneider, Rayfel, Beukelman, Timothy, Morgan, Esi, Graham, T. Brent, Ibarra, Maria, Ruas, Yonit Sterba, Klein-Gitelman, Marisa, Onel, Karen, Punaro, Marilynn, Toib, Dana, Van Mater, Heather, Weiss, Jennifer E., Weiss, Pamela F., Kwok, Timothy S. H., Bisaillon, Jacinthe, Smith, Christine, Brosseau, Lucie, Stinson, Jennifer, Huber, Adam M., Duffy, Ciaran M., April, Karine Toupin, Lewandowski, Laura B., Scott, Christiaan, Li, Suzanne C., Torok, Kathryn S., Rabinovich, C. Egla, Hong, Sandy D., Becker, Mara L, Dedeoglu, Fatma, Ibarra, Maria F., Ferguson, Polly J, Fuhbrigge, Rob C., Stewart, Katie G., Pope, Elena, Laxer, Ronald M., Mason, Thomas G., Higgins, Gloria C., Li, Xiaohu, Punaro, Marilynn G., Tomlinson, George, Pullenayegum, Eleanor, Matelski, John, Feldman, Brian M., Manthiram, Kalpana, Correa, Hernan, Edwards, Kathryn, Oberle, Edward J., Bayer, Michelle, Co, Dominic O., Baris, Hatice Ezgi, Chiu, Yvonne, Huber, Adam, Kim, Susan, Orandi, Amir B., Baszis, Kevin W., Dharnidharka, Vikas, Hoeltzel, Mark F., Reed, Ann, Goh, Y. Ingrid, Schnabel, Anja, Range, Ursula, Hahn, Gabriele, Siepmann, Timo, Berner, Reinhard, Hedrich, Christian Michael, Stevens, Brandi, Li, Suzanne, Hershey, Nicole, Curran, Megan, Higgins, Gloria, Moore, Katharine, Rabinovich, Egla, Stevens, Anne M., Connelly, Mark, Luca, Nadia, Spiegel, Lynn, Tsimicalis, Argerie, Luca, Stephanie, Tajuddin, Naweed, Berard, Roberta, Barsalou, Julia, Campillo, Sarah, Dancey, Paul, Duffy, Ciaran, Feldman, Brian, Johnson, Nicole, McGrath, Patrick, Shiff, Natalie, Tse, Shirley, Tucker, Lori, Victor, Charles, Lalloo, Chitra, Harris, Lauren, Cafazzo, Joseph, Laxer, Ronald, Bullock, Danielle R., Vehe, Richard K., Zhang, Lei, Correll, Colleen K., Ganguli, Suhas, Shenberger, Max, Korumilli, Ritesh, Gottlieb, Beth, Rodriguez, Martha, de Ranieri, Deirdre, Wagner-Weiner, Linda, Tesher, Melissa, Wojcicki, Elizabeth Roth, Maletta, Kristyn L., Malloy, Marsha, Thomson, Sarah, Olson, Judyann C., Sule, Sangeeta, Rubinstein, Tamar B., Okamura, Daryl M., Chua, Annabelle, Greenbaum, Laurence A., Lane, Jerome C., Ardoin, Stacy P., Woo, Jennifer M. P., Malloy, Marsha M., Jegers, James A., Hahn, Dustin J., Hintermeyer, Mary K., Martinetti, Stacey M., Heckel, Gretchen R., and Roth-Wojcicki, Elizabeth L.

Subjects
Rheumatology, Immunology and Allergy, Pediatrics, Perinatology, and Child Health, Meeting Abstracts
Abstract

Table of Contents P1 Serologic evidence of gut-driven systemic inflammation in juvenile idiopathic arthritis Lampros Fotis, Nur Shaikh, Kevin Baszis, Anthony French, Phillip Tarr P2 Oral health and anti-citrullinated peptide antibodies (ACPA) in juvenile idiopathic arthritis Sriharsha Grevich, Peggy Lee, Sarah Ringold, Brian Leroux, Hannah Leahey, Megan Yuasa, Jessica Foster, Jeremy Sokolove, Lauren Lahey, William Robinson, Joshua Newsom, Anne Stevens P3 Novel autoantigens for endothelial cell antibodies in pediatric rheumatic diseases identified by proteomics Rie Karasawa, Mayumi Tamaki, Megumi Tanaka, Toshiko Sato, Kazuo Yudoh, James N. Jarvis P4 Transcriptional profiling reveals monocyte signature associated with JIA patient poor response to methotrexate Halima Moncrieffe, Mark F. Bennett, Monica Tsoras, Lorie Luyrink, Huan Xu, Sampath Prahalad, Paula Morris, Jason Dare, Peter A. Nigrovic, Margalit Rosenkranz, Mara Becker, Kathleen M. O’Neil, Thomas Griffin, Daniel J. Lovell, Alexei A. Grom, Mario Medvedovic, Susan D. Thompson P5 A multi-dimensional genomic map for polyarticular juvenile idiopathic arthritis Lisha Zhu, Kaiyu Jiang, Laiping Wong, Michael J Buck, Yanmin Chen, Halima Moncrieffe, Laura Brungs, Tao Liu, Ting Wang, James N Jarvis P6 Tocilizumab for treatment of children with refractory JIA Khaled Alsaeid, Jasim Alfailakawi, Hamid Alenezi, Hazim Alsaeed P7 Clinical characteristics of the initial patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry Tim Beukelman, Marc Natter, Norm Ilowite, Kelly Mieszkalski, Grendel Burrell, Brian Best, Helen Bristow, Shannon Carr, Anne Dennos, Rachel Kaufmann, Yukiko Kimura, Laura Schanberg P8 Comparative performance of small and large clinical centers in a comprehensive pediatric rheumatology disease registry Peter R Blier P9 Clinical characteristics of children with membranous lupus nephritis: The Childhood Arthritis and Rheumatology Research Alliance Legacy Registry Alexis Boneparth, Scott E. Wenderfer, L. Nandini Moorthy, Suhas M. Radhakrishna, Anna Carmela P. Sagcal-Gironella, Emily von Scheven P10 Rituximab use in pediatric lupus anticoagulant hypoprothrombinemia syndrome - a two center experience Kader Cetin Gedik, Salma Siddique, Cassyanne L. Aguiar, Doruk Erkan P11 Predictors of complementary and alternative medicine use and response in children with musculoskeletal conditions Ezra Cohen, Yvonne Lee, Michelle Dossett, Darshan Mehta, Roger Davis P12 Comparison of pediatric rheumatology and nephrology survey results for the treatment of refractory proliferative lupus nephritis and renal flare in juvenile SLE Mileka Gilbert, Beatrice Goilav, Esra Meidan, Joyce Hsu, Alexis Boneparth, Anabelle Chua, Stacy Ardoin, Scott E. Wenderfer, Emily Von Scheven, Natasha M. Ruth P13 Transitioning lupus patients from pediatric to adult rheumatology Joyce Hui-Yuen, Kader Cetin Gedik, Liza Bermudez, Ashlea Cook, Lisa Imundo, Amy Starr, Andrew Eichenfield, Anca Askanase P14 The systemic juvenile idiopathic arthritis cohort of the Childhood Arthritis & Rheumatology Research Alliance Registry Ginger Janow, Laura E. Schanberg, Soko Setoguchi, Victor Hasselblad, Elizabeth D. Mellins, Rayfel Schneider, Yukiko Kimura, The CARRA Legacy Registry Investigators P15 Results of the pilot study of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans for new-onset systemic juvenile idiopathic arthritis Yukiko Kimura, Sriharsha Grevich, Timothy Beukelman, Esi Morgan, T Brent Graham, Maria Ibarra, Yonit Sterba Ruas, Marisa Klein-Gitelman, Karen Onel, Sampath Prahalad, Marilynn Punaro, Sarah Ringold, Dana Toib, Heather Van Mater, Jennifer E. Weiss, Pamela F. Weiss, Kelly Mieszkalski, Laura E. Schanberg P16 A systemic review of pain relief modalities in juvenile idiopathic arthritis: First step in developing a novel decision support intervention Timothy S. H. Kwok, Jacinthe Bisaillon, Christine Smith, Lucie Brosseau, Jennifer Stinson, Adam M. Huber, Ciaran M. Duffy, Karine Toupin April P17 Barriers and facilitators to care retention for pediatric systemic lupus erythematous patients in South Africa: A qualitative study Laura B Lewandowski, Christiaan Scott P18 Evaluating the feasibility of conducting comparative effectiveness studies in juvenile Localized Scleroderma (jLS) Suzanne C. Li, Kathryn S. Torok, C. Egla Rabinovich, Sandy D. Hong, Mara L Becker, Fatma Dedeoglu, Maria F. Ibarra, Polly J Ferguson, Rob C. Fuhbrigge, Katie G. Stewart, Elena Pope, Ronald M. Laxer, Thomas G. Mason, Gloria C. Higgins, Xiaohu Li, Marilynn G. Punaro, George Tomlinson, Eleanor Pullenayegum, John Matelski, Laura Schanberg, Brian M. Feldman P19 Tonsillar histology in patients with periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome Kalpana Manthiram, Hernan Correa, Kathryn Edwards P20 Clinical course of juvenile dermatomyositis presenting as skin predominant disease Edward J. Oberle, Michelle Bayer, Dominic O. Co, Hatice Ezgi Baris, Yvonne Chiu, Adam Huber, Susan Kim P21 A Survey of musculoskeletal ultrasound practices of pediatric rheumatologists in North America Edward J Oberle, Timothy Beukelman P22 Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: A survey of pediatric rheumatologists by the Childhood Arthritis and Rheumatology Research Alliance Amir B. Orandi, Kevin W. Baszis, Vikas Dharnidharka, Mark F. Hoeltzel, for the CARRA JDM Committee P23 CARRA dermatomyositis CTP pilot study Ann Reed, Adam Huber, George Tomlinson, Eleanor Pullenayegum, John Matelski, Y. Ingrid Goh, Laura Schanberg, Brian M. Feldman P24 Unexpectedly high incidences and prolonged disease activity in children with chronic non-bacterial osteomyelitis (CNO) as compared to bacterial osteomyelitis Anja Schnabel, Ursula Range, Gabriele Hahn, Timo Siepmann, Reinhard Berner, Christian Michael Hedrich P25 Juvenile systemic sclerosis cohort within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry: Follow up characteristics Brandi Stevens, Kathryn S. Torok, Suzanne Li, Nicole Hershey, Megan Curran, Gloria Higgins, Katharine Moore, Egla Rabinovich, Anne M. Stevens, for the CARRA Registry Investigators P26 Development and usability testing of an iPad and desktop psycho-educational game for children with Juvenile Idiopathic Arthritis and their parents Jennifer Stinson, Mark Connelly, Adam Huber, Nadia Luca, Lynn Spiegel, Argerie Tsimicalis, Stephanie Luca, Naweed Tajuddin, Roberta Berard, Julia Barsalou, Sarah Campillo, Paul Dancey, Ciaran Duffy, Brian Feldman, Nicole Johnson, Patrick McGrath, Natalie Shiff, Shirley Tse, Lori Tucker, Charles Victor P27 iCanCopeTM: User-centred design and development of a smartphone app to support self-management for youth with arthritis pain Jennifer Stinson, Chitra Lalloo, Lauren Harris, Joseph Cafazzo, Lynn Spiegel, Brian Feldman, Nadia Luca, Ronald Laxer P28 Accessing pediatric rheumatology care: Despite barriers, few parents prefer telemedicine Danielle R. Bullock, Richard K. Vehe, Lei Zhang, Colleen K. Correll1 P29 Exploration of factors contributing to time to achieve clinically inactive disease (CID) in juvenile idiopathic arthritis (JIA): A preliminary report Suhas Ganguli, Max Shenberger, Ritesh Korumilli, Beth Gottlieb P30 Pediatric rheumatology referral patterns: Presenting complaints of new patients at a large, urban academic center Martha Rodriguez, Deirdre de Ranieri, Karen Onel, Linda Wagner-Weiner, Melissa Tesher P31 Quality improvement (QI) initiatives in childhood systemic lupus erythematosus (cSLE) Elizabeth Roth Wojcicki, Kristyn L. Maletta, Dominic O. Co, Marsha Malloy, Sarah Thomson, Judyann C. Olson P32 Proliferative lupus nephritis in juvenile SLE: Support from the pediatric nephrology community for the definitions of responsiveness and flare in the 2012 consensus treatment plans Scott E. Wenderfer, Mileka Gilbert, Joyce Hsu, Sangeeta Sule, Tamar B. Rubinstein, Beatrice Goilav, Daryl M. Okamura, Annabelle Chua, Laurence A. Greenbaum, Jerome C. Lane, Emily von Scheven, Stacy P. Ardoin, Natasha M. Ruth P33 The steroid taper app: Making of a mobile app Jennifer M. P. Woo, Marsha M. Malloy, James A. Jegers, Dustin J. Hahn, Mary K. Hintermeyer, Stacey M. Martinetti, Gretchen R. Heckel, Elizabeth L. Roth-Wojcicki, Dominic O. Co

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