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21,147 results on '"School of Biosciences"'

1. Beta Testing of a New Assessment in Huntington's Disease (HD) (CAPIT-HD Beta)

Author: School of Biosciences - Cardiff University, University Hospital of Wales, National Reference Center for Huntington's disease Cognitive Neurology Unit, Institut National de la Santé Et de la Recherche Médicale, France, Manchester Centre for Genomic Medicine - St. Mary's Hospital University of Manchester, and George-Huntington-Institut GmbH
Published: 2017

2. Role of the Microbiome in Graves' Orbitopathy (Indigo)

Author: Cultech Ltd, Port Talbot, UK, Universität Duisburg-Essen, School of Medicine and School of Biosciences, Cardiff University, Cardiff, UK, and IDRA Laboratory, Parco Tecnologico Padano s.r.l, Lodi, Italy
Published: 2015

3. Curative effect of Plumbago indica root extract on thioacetamide induced hepatotoxicity in experimental rats

Author: NA, Binil, Eldhose; 1) School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India 2) Department of Radiation Medicine, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC 20057, USA, Jayesh, Kuriakose; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India, Sankunni, Latha Mukalel; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India, NA, Binil, Eldhose; 1) School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India 2) Department of Radiation Medicine, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC 20057, USA, Jayesh, Kuriakose; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India, and Sankunni, Latha Mukalel; School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala-686560, India
Abstract: The root parts of Plumbago indica is widely used in the Indian Ayurvedic traditional system. The study was designed to evaluate the hepato curative activity Plumbago Indica (PLBM) methanolic root extracts at different doses (100 and 200 mg/kg bw) against thioacetamide induced liver damage in albino wistar rats. Liver damage was induced by administration of Thioacetamide (100 mg/kg bw) and was assessed by evaluating the activity of liver-function marker enzymes, antioxidant enzymes and lipid peroxidation. The liver sections were evaluated for histopathological changes. PLBM significantly (p ≤ 0.05) reversed the elevation of serum liver enzymes and hepatic levels of antioxidant markers. Histopathological findings also confirmed the curative effect of Plumbago Indica in a dose dependent manner. Thus this study scientifically rationale the use of Plumbago indica root as a promising drug against various liver disorders.
Published: 2017

4. Dissimilarity of the gut–lung axis and dysbiosis of the lower airways in ventilated preterm infants

Author: Gallacher, David, Mitchell, Emma, Alber, Dagmar, Wach, Richard, Klein, Nigel, Marchesi, Julian R., Kotecha, Sailesh, Department of Child Health, School of Medicine, Cardiff University, Cardiff, UK, Institute of Child Health, University College London, London, UK, Neonatal Unit, North Bristol NHS Trust, Bristol, UK, School of Biosciences, Cardiff University, Cardiff, UK, and Division of Integrative Systems Medicine and Digestive Disease, Imperial College London, London, UK
Subjects: DNA, Bacterial, Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, RJ101, Respiratory System, 030106 microbiology, Feces, 03 medical and health sciences, Ureaplasma, 0302 clinical medicine, RNA, Ribosomal, 16S, 030225 pediatrics, medicine, Humans, Microbiome, Respiratory system, Lung, 11 Medical and Health Sciences, Bronchopulmonary Dysplasia, Bacteria, medicine.diagnostic_test, biology, business.industry, Infant, Newborn, respiratory system, medicine.disease, biology.organism_classification, Gastrointestinal Microbiome, respiratory tract diseases, Trachea, Bronchoalveolar lavage, medicine.anatomical_structure, Bronchopulmonary dysplasia, Immunology, Dysbiosis, Female, Airway, business, Bronchoalveolar Lavage Fluid, Infant, Premature
Abstract: BackgroundChronic lung disease of prematurity (CLD), also called bronchopulmonary dysplasia, is a major consequence of preterm birth, but the role of the microbiome in its development remains unclear. Therefore, we assessed the progression of the bacterial community in ventilated preterm infants over time in the upper and lower airways, and assessed the gut–lung axis by comparing bacterial communities in the upper and lower airways with stool findings. Finally, we assessed whether the bacterial communities were associated with lung inflammation to suggest dysbiosis.MethodsWe serially sampled multiple anatomical sites including the upper airway (nasopharyngeal aspirates), lower airways (tracheal aspirate fluid and bronchoalveolar lavage fluid) and the gut (stool) of ventilated preterm-born infants. Bacterial DNA load was measured in all samples and sequenced using the V3–V4 region of the 16S rRNA gene.ResultsFrom 1102 (539 nasopharyngeal aspirates, 276 tracheal aspirate fluid, 89 bronchoalveolar lavage, 198 stool) samples from 55 preterm infants, 352 (32%) amplified suitably for 16S RNA gene sequencing. Bacterial load was low at birth and quickly increased with time, but was associated with predominant operational taxonomic units (OTUs) in all sample types. There was dissimilarity in bacterial communities between the upper and lower airways and the gut, with a separate dysbiotic inflammatory process occurring in the lower airways of infants. Individual OTUs were associated with increased inflammatory markers.ConclusionsTaken together, these findings suggest that targeted treatment of the predominant organisms, including those not routinely treated, such as Ureaplasma spp., may decrease the development of CLD in preterm-born infants.
Published: 2020

5. Multi-omics approaches confirm metal ions mediate the main toxicological pathways of metal-bearing nanoparticles in lung epithelial A549 cells

Author: Dekkers, Susan, Williams, Tim D., Zhang, Jinkang, Zhou, Jiarui (Albert), Vandebriel, Rob J., De La Fonteyne, Liset J. J., Gremmer, Eric R., He, Shan, Guggenheim, Emily J., Lynch, Iseult, Cassee, Flemming R., De Jong, Wim H., Viant, Mark R., National Institute for Public Health and the Environment (RIVM), School of Biosciences, Centre for Systems Biology, and School of Geography Earth and Environmental Sciences
Abstract: Our analyses confirm that the dissolution of metal ions mediates the main toxicological pathways of silver and zinc oxide nanoparticles.
Published: 2018

6. Assessment of Anticarcinogenic Potential of Vitex trifolia and Triticum aestivum Linn by In Vitro Rat Liver Microsomal Degranulation

Author: Mathankumar, Marimuthu; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Tamizhselvi, Ramasamy; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Manickam, Venkatraman; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Purohit, Gaurav; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Mathankumar, Marimuthu; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Tamizhselvi, Ramasamy; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, Manickam, Venkatraman; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, and Purohit, Gaurav; School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu
Abstract: Objective: The main objective of this preliminary study is to confirm the synergistic anticarcinogenic potential of Vitex trifolia and Triticum aestivum ethanolic extracts. Materials and Methods: Rat hepatic microsomal degranulation is a short - term technique that has been used for the detection of potential chemical carcinogens, in vitro. The present study has been carried out to study the inhibition of ribosome- membrane disruption against 3, 8-Diamino-5-ethyl-6-pheylphenanthridinium bromide (EB), as the degranulating agent, by measuring the RNA/protein ratios of microsomal membranes in the presence or absence of V.trifolia and T. aestivum extracts. These two extracts were further evaluated for cytotoxic effect in HCT 116 and A549 cell lines. Results: V. trifolia and T. aestivum protects hepatic microsomes against the degranulatory attack by the carcinogen EB showed a significant reduction in the proliferation of the HCT 116 and A549 cancer cell lines. Conclusion: The ethanolic extracts of the plants, V. trifolia and T. aestivum individually possessed anti-degranulatory potential. Importantly they act synergistically, possess appreciable anticarcinogenic properties, based on their ability to inhibit EB induced liver microsomal degranulation. Further these extracts inhibit cell proliferation of cancer cell lines.
Published: 2015

7. Thermal tolerance of coral photosymbionts: genetic factors and strategies to pursue genetic enhancement

Author: Steinberg, Peter, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW, van Oppen, Madeleine, School of BioSciences, The University of Melbourne, Levin, Rachel, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW, Steinberg, Peter, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW, van Oppen, Madeleine, School of BioSciences, The University of Melbourne, and Levin, Rachel, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW
Abstract: Dinoflagellates of the genus Symbiodinium form essential symbioses with reef building corals, underpinning the entire ecological foundation of coral reefs. Corals rely on photosynthate produced by Symbiodinium for their growth and calcification, which in turn forms the reef framework. Increased sea surface temperature due to climate change triggers the loss of Symbiodinium from corals (coral bleaching), which can result in coral death. Different genetic variants of Symbiodinium exhibit diverse thermal tolerances that influence the thermal bleaching thresholds of their coral host. However, despite decades of research into Symbiodinium biology, determinants of Symbiodinium thermal tolerance are still largely unresolved. Therefore, I aimed to unlock the basis of Symbiodinium thermal tolerance using a comparative physiology-genomics approach, and subsequently using this new knowledge, aimed to develop novel strategies that promote genetic manipulation of Symbiodinium. In this thesis, I discovered that thermal tolerance of type C1 Symbiodinium is driven by up-regulation of genes and functional gene groups responsible for sexual reproduction, scavenging of reactive oxygen species, and protein folding that maintain photosynthetic ability and limit reactive oxygen species production under heat stress. I also uncovered the first entire genome of a Symbiodinium virus along with hundreds of transcripts from viruses that infect Symbiodinium, whose transcriptional regulation under heat stress may contribute to Symbiodinium thermal sensitivity. Next, I successfully removed cell walls from live Symbiodinium to create the first Symbiodinium protoplasts and achieved Symbiodinium protoplast fusion, a key step in creating hybrid Symbiodinium cells with novel genetic combinations for ideal traits. Finally, using these discoveries, I developed a theoretical framework for Symbiodinium genetic engineering that incorporates Symbiodinium genetic elements, viral genetic elements, and Symbiod
Published: 2017

8. In Vitro Antioxidant Activity of Flowers and Fruits of Alstonia scholaris

Author: James, Joel; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Veettil, Arun Kumar Thaliyil; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Pratyush, Kumar; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Misra, Chandra Shekhar; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Sahadevan, Lipin Dev Mundur; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Thankamani, V; Department of Biotechnology, University of Kerala), James, Joel; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Veettil, Arun Kumar Thaliyil; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Pratyush, Kumar; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Misra, Chandra Shekhar; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., Sahadevan, Lipin Dev Mundur; School of Biosciences and Technology VIT University, Vellore-632014 Tamil Nadu, India., and Thankamani, V; Department of Biotechnology, University of Kerala)
Abstract: The ethnobotanical and pharmacological evaluation of plant based chemicals have shown rapid strides in the last few decades. Plants have been a rich source of important therapeutic agents and form the basis of herbal systems of medicine, like ayurveda, resulting in the revival of ancient traditions of medicine. The present study was carried out to investigate the anti oxidant potential of the inflorescence and fruits of Alstonia scholaris using an in vitro model system like DPPH assay and Beta carotene Assay. The methanol extract of the flower showed powerful antioxidant activity by DPPH and Beta-carotene assays in comparison with the standard butylated hydroxy toluene (BHT), l- ascorbic acid. For DPPH assay the IC-50 value was also calculated and was found to have a significant correlation between benzene extract of flower and methanol extract of fruits. Overall, the methanol extracts of flower showed higher anti oxidant activity than the fruit. Keywords: Alstonia scholaris ,anti oxidant potential, DPPH, Beta Carotene.
Published: 2012

9. Differential toxicity of antifungal protein AFP against mutants of Fusarium oxysporum

Author: Magdalena Martín-Urdiroz; Department of Genetics, University of Córdoba, Córdoba, Spain School of Biosciences, University of Exeter, Exeter, United Kingdom, Ana L. Martínez-Rocha; Department of Genetics, University of Córdoba, Córdoba, Spain School of Biosciences, University of Exeter, Exeter, United Kingdom, Antonio Di Pietro; Department of Genetics, University of Córdoba, Córdoba, Spain, Álvaro Martínez-del-Pozo; Departament of Biochemistry and Molecular Biology I, Faculty of Chemical Sciences, Complutense University of Madrid, Madrid, Spain, M. Isabel G. Roncero; Department of Genetics, University of Córdoba, Córdoba, Spain, Magdalena Martín-Urdiroz; Department of Genetics, University of Córdoba, Córdoba, Spain School of Biosciences, University of Exeter, Exeter, United Kingdom, Ana L. Martínez-Rocha; Department of Genetics, University of Córdoba, Córdoba, Spain School of Biosciences, University of Exeter, Exeter, United Kingdom, Antonio Di Pietro; Department of Genetics, University of Córdoba, Córdoba, Spain, Álvaro Martínez-del-Pozo; Departament of Biochemistry and Molecular Biology I, Faculty of Chemical Sciences, Complutense University of Madrid, Madrid, Spain, and M. Isabel G. Roncero; Department of Genetics, University of Córdoba, Córdoba, Spain
Abstract: Antifungal protein (AFP) from Aspergillus giganteus was assayed for toxicity against the Fusarium oxysporum wild-type strain and mutants in genes involved in cell signaling (ΔpacC, pacCc Δfmk1) or cell-wall biogenesis (ΔchsV, Δchs7, Δgas1). The mutants were classified into two groups according to their sensitivity to AFP: ΔpacC, Δgas1 and Δchs7, which were significantly more resistant to AFP than the wild-type, and pacCC, Δfmk1 and ΔchsV, which were more sensitive. Western blot analysis revealed increased binding of AFP to the three resistant mutants, ΔpacC, Δgas1 and Δchs7, but also to ΔchsV, indicating that differential binding may not be a key determinant for sensitivity. Addition of Ca2+ or K+ dramatically reduced antifungal activity and binding of AFP, suggesting that these cations compete for the same targets as AFP at the surface of the fungal cell. [Int Microbiol 2009; 12(2):115-121]
Published: 2010

10. The Evolution of Diversity: Sexual selection and natural selection on the social signals of gliding lizards.

Author: Ord, Terry, Evolution & Ecology Research Centre, Faculty of Science, UNSW, Stuart-Fox, Devi, School of BioSciences, University of Melbourne, Klomp, Danielle Alice, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW, Ord, Terry, Evolution & Ecology Research Centre, Faculty of Science, UNSW, Stuart-Fox, Devi, School of BioSciences, University of Melbourne, and Klomp, Danielle Alice, Biological, Earth & Environmental Sciences, Faculty of Science, UNSW
Abstract: Diversity in animal colour and form can often be attributed to communication signals, which play an important role in species recognition and mate choice. Divergence of signals among populations is therefore thought to be a driver of speciation. This thesis examines signalling processes in the species rich agamid genus, Draco, to understand their influence on signal design, signal divergence and ultimately speciation. Draco lizards are known as ‘gliding lizards’, as they have retractable gliding membranes. They communicate with extendable throat-fans, called dewlaps, which are diverse in colour, shape and size among species. Chapter two assesses the importance of dewlap signal design for detection and recognition in Draco melanopogon, by presenting free-living lizards with robots displaying dewlaps of different designs. Dewlap design does not affect the latency of signal detection by conspecifics, but once the robot dewlap had been detected, males responded with greater intensity to dewlaps that best resembled the species’ typical design, suggesting pattern is important in species recognition. As signal components may evolve differently in populations exposed to different selection pressures, chapter three assess the relationships between the dewlap components (colour and size) and aspects of their environments. Males of different species employ colour contrast and dewlap size as alternative strategies for effective communication, and predation intensity may play a role in which strategy a species employs. Further, correlations between male dewlap components and sexual dimorphism suggest that sexual selection is also a major factor influencing dewlap design. Chapter four shows that the different gliding membrane colouration of two populations of Draco cornutus closely match the colours of freshly fallen leaves in their respective habitats as they appear to the visual system of predatory birds. This suggests the populations have diverged in colouration to mimic the c
Published: 2016

11. Bacterial toxicity of biomimetic green zinc oxide nanoantibiotic: insights into ZnONP uptake and nanocolloid–bacteria interfaceElectronic supplementary information (ESI) available. See DOI: 10.1039/c8tx00267c

Author: Ahmed, Bilal, Solanki, Bushra, Zaidi, Almas, Khan, Mohammad Saghir, MusarratPresent address: School of Biosciences, Javed, Biodiversity, and University, Baba Ghulam Shah Badshah
Abstract: This study was aimed to fill the critical gap of knowledge regarding the interaction between green zinc oxide nanoparticles (ZnONPs) and bacterial interface. Wurtzite phase ZnONPs with a band gap energy of 3.28 eV were produced by exploiting a simple and green biosynthesis method using an inexpensive precursor of A. indicaleaf extract and zinc nitrate. ZnONPs were characterized using UV-Vis spectroscopy, XRD, FTIR, SEM, EDX, DLS, TEM, and zeta-potential analysis. The primary size obtained was 26.3 nm (XRD) and 33.5 ± 6.5 nm (TEM), whereas, the secondary size was found to be 287 ± 5.2 nm with −32.8 ± 1.8 mV ζ-potential denoting the physical colloid chemistry of ZnONPs. Crystallinity and the spherical morphology of ZnONPs were also evident with some sort of particle agglomeration. ZnONPs retained plant functional groups endorsing their hydrophilic character. The antibacterial and antibiofilm activity of ZnONPs was significant (p≤ 0.05) and the MIC/MBC against most frequent clinical isolates of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureusranged from 0.5 to 1.0 (MIC)/1.0 to 1.5 mg ml−1(MBC). The dissolution of ZnONPs to Zn2+ions in a nutrient medium increased as a result of interaction with the bacterial surface and metabolites. Substantial surface binding of ZnONPs followed by intracellular uptake disrupted the cell morphology and caused obvious injury to the cell membrane. Interrupted bacterial growth kinetics, loss of cell respiration, enhanced production of intracellular ROS, and the leakage of the cytoplasmic content unequivocally suggested a strong interaction of ZnONPs with the exterior cell surface and intracellular components, eventually leading to cell death and destruction of biofilms. Overall, the results elucidated eco-friendly production of ZnONPs expressing a prominent interfacial correlation with bacteria and hence, prospecting the use of green ZnONPs as effective nanoantibiotics.
Published: 2019
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12. Estrogenic and anti-proliferative activity of water extract of Glycyrhizzic uralensis (licorice root)

Author: Fundamental Research Grant Scheme (FRGS/2/2010/SKK/TAYLOR/03/1), Ministry of Higher Education, Malaysia, Poh, Melissa; Taylor’s University (Lakeside Campus), No 1, Jalan Taylor’s, 47500, Subang Jaya Selangor Darul Ehsan Malaysia, Yin, Chia Yoke; School of Biosciences, Division of Medicine, Pharmacy and Health Sciences, Taylor’s University, Selangor, Malaysia., Fundamental Research Grant Scheme (FRGS/2/2010/SKK/TAYLOR/03/1), Ministry of Higher Education, Malaysia, Poh, Melissa; Taylor’s University (Lakeside Campus), No 1, Jalan Taylor’s, 47500, Subang Jaya Selangor Darul Ehsan Malaysia, and Yin, Chia Yoke; School of Biosciences, Division of Medicine, Pharmacy and Health Sciences, Taylor’s University, Selangor, Malaysia.
Abstract: Licorice is the root of Glycyrrhiza uralensis, which is a commonly used herb in traditional Chinese medicine. Licorice extract has been claimed to have anti-cancer, anti-viral, anti-inflammatory and anti-diabetic activities. This study evaluated the estrogenic effect of licorice root water extract on Ishikawa cells and related it to its effect on cell proliferation using various cell lines in comparison to glycyrrhizic acid (GA). This study showed that licorice root extract exhibited estrogenic property while decreasing cell proliferation thus suggesting possible use in estrogen replacement agent with anti-proliferative property. Even though GA is the most studied active component in licorice, these two properties were not seen in the cell lines tested; hence suggesting that GA is not responsible for these activities. These results showed that licorice could be further studied as an estrogen replacement agent as it does not cause an increase in cell proliferation in the breast and uterus.
Published: 2013

13. A systematic study of the formation of mesostructured silica using surfactant ruthenium complexes in high- and low-concentration regimesElectronic supplementary information (ESI) available: Discussion of CTAB templated silica and further images. See DOI: 10.1039/b807549b

Author: Katherine E. Amos, Nicholas J. Brooks, Nicola C. KingPresent address: School of Biosciences, Geoffrey Pope Building, University of Exeter, Stocker Ro, Songhai Xie, Jesús Canales-Vázquez, Mark J. Danks, Helen B. Jervis, Wuzong Zhou, John M. Seddon, and Duncan W. Bruce
Abstract: Mesostructured silica can be prepared by surfactant templating either under conditions of low surfactant template concentration (so-called liquid crystal templating) or from a pre-formed mesophase at higher surfactant concentrations (true liquid crystal templating). In this study, the structural properties of such silica products prepared using a surfactant bipyridine complex of Ru(ii) are compared with similar products templated with a conventional cationic surfactant, CTAB (cetyltrimethylammonium bromide). Templating with this ruthenium metallosurfactant leads to well-ordered mesoporous silica with catalytically active RuO2nanoparticles distributed uniformly within the silica pores. [ABSTRACT FROM AUTHOR]
Published: 2008
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14. Energy transfer in thermal and hyperthermal collisions between CN(X2Σ+, v = 2) in selected rotational levels (Ni = 0, 1, 6, 10, 15 and 20) and N2

Author: OlkhovPresent address: School of Biosciences, Rouslan V., Building, Geoffrey Pope, Exeter, University of, Road, Stocker, Exeter, R.V.Olkhov@exeter.ac.uk., U.K. EX4 4QD; E-mail:, and Smith, Ian W. M.
Abstract: We report rate coefficients (ktot,Ni) for total removal of CN(X2Σ+, v = 2, Ni) radicals from selected rotational levels (Ni = 0, 1, 6, 10, 15 and 20) and for state-to-state rotational energy transfer (ki→f) between levels Ni and other rotational levels Nf in single collisions with N2. CN radicals have been generated using two sources: (a) the pulsed laser photolysis of ICN at 266 nm, which generates translationally ‘hot’ CN radicals; and (b) the pulsed laser photolysis of NCNO at 570 nm, which generates CN radicals with translational energies close to the average value at 298 K. Comparison of the values of ktot,Ni obtained using these two sources of CN demonstrates: firstly, that the same results are obtained as long as time is allowed for the translationally hot CN radicals generated from ICN to be thermalised before radicals are promoted to a specific rotational level in v = 2 using a tuneable infrared ‘pump’ laser operating at ca. 2.45 μm; and secondly, that the rate coefficients decrease, but the averaged cross-sections remain approximately constant, as the excess translational energy in CN radicals is moderated by collisions. With NCNO as the source of CN radicals, the observed values of ktot,Ni do not depend on the delay between the pulses from the photolysis and pump lasers. Finally, we demonstrate that, for the non-reactive collision partner N2 and with allowances made for the rate coefficients that are too small to measure directly, the sum of the state-to-state rate coefficients, Σfki→f, for rotational energy transfer from a selected initial level Ni agrees quite well with the value of ktot,Ni for total transfer from the same initial level. The values of ktot,Ni and of the state-to-state rate coefficients are compared with similar, earlier, results in which helium and argon were the collision partners. The relevance of these results to the study of collisions of CN with reactive collision partners is briefly discussed.
Published: 2006
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15. The synthesis of mesoporous silicates containing bimetallic nanoparticles and magnetic properties of PtCo nanoparticles in silica.

Author: Nicola C. KingPresent address: School of Biosciences, Geoffrey Pope Building, University of Exeter, Stocker Road, Exeter, UK EX4 4QD., Ross A. Blackley, M. Lesley Wears, David M. Newman, Wuzong Zhou, and Duncan W. Bruce
Published: 2006

16. The preparation by true liquid crystal templating of mesoporous silicates containing nanoparticulate metals.

Author: Nicola C. KingPresent address: School of Biosciences, Geoffrey Pope Building, University of Exeter, Stocker Road, Exeter, UK EX4 4QD., Ross A. Blackley, Wuzong Zhou, and Duncan W. Bruce
Published: 2006

17. The synthesis of mesoporous silicates containing bimetallic nanoparticles and magnetic properties of PtCo nanoparticles in silicaElectronic supplementary information (ESI) available: X-Ray diffraction pattern; EDX spectra. See DOI: 10.1039b607471e

Author: KingPresent address: School of Biosciences, Nicola C., Building, Geoffrey Pope, Exeter, University of, Ro, Stocker, Blackley, Ross A., Wears, M. Lesley, Newman, David M., Zhou, Wuzong, and Bruce, Duncan W.
Abstract: Using a one-pot approach employing true liquid crystal templating on neutral surfactants and simple metal salt precursors, mesostructured, mesoporous silicates have been prepared in which bimetallic nanoparticles are deposited; magnetic properties of PtCo systems so prepared are evaluated.
Published: 2006
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18. The preparation by true liquid crystal templating of mesoporous silicates containing nanoparticulate metalsElectronic supplementary information (ESI) available: TEM image; 29Si MAS-NMR spectra. See DOI: 10.1039b607470g

Author: KingPresent address: School of Biosciences, Nicola C., Building, Geoffrey Pope, Exeter, University of, Ro, Stocker, Blackley, Ross A., Zhou, Wuzong, and Bruce, Duncan W.
Abstract: Mesostructured silicates containing metal nanoparticles have been synthesised viatemplating around a pre-formed, metal-containing mesophase using a non-ionic surfactant.
Published: 2006
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19. Ethical Publishing: How Do We Get There?

Author: Racimo, Fernando, Galtier, Nicolas, De Herde, Véronique, Aubert Bonn, Noémie, Phillips, Ben, Guillemaud, Thomas, Bourguet, Denis, Globe Institute, Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Rotterdam School of Management, RSM Erasmus University, Hasselt University (UHasselt), School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, Institut Sophia Agrobiotech (ISA), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Côte d'Azur (UCA), Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM), University of Copenhagen = Københavns Universitet (UCPH), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), Université Catholique de Louvain = Catholic University of Louvain (UCL), University of Melbourne, no funding, Racimo, Fernando, Galtier, Nicolas, De Herde, Véronique, AUBERT BONN, Noemie, Phillips, Ben, Guillemaud, Thomas, Bourget, Denis, Sytra -Earth and Life Institute, UCLouvain, Research Group of Healthcare and Ethics, Faculty of Medicine and Life Sciences, Hasselt Universty, School of BioSciences, Faculty of Science, University of Melbourne, Institut National de la Recherche Agronomique (INRA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)
Subjects: open access, collective action, [SHS.STAT]Humanities and Social Sciences/Methods and statistics, [SDV]Life Sciences [q-bio], [SHS.INFO]Humanities and Social Sciences/Library and information sciences, academic publishing, journals, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, ethics, [SHS]Humanities and Social Sciences, [SHS.HISPHILSO]Humanities and Social Sciences/History, Philosophy and Sociology of Sciences, [SCCO]Cognitive science, peer-review, [SDE]Environmental Sciences, open science, General Earth and Planetary Sciences, journal, recommendation model, open-access, General Environmental Science
Abstract: International audience; The academic journal publishing model is deeply unethical: today, a few major, for-profit conglomerates control more than 50% of all articles in the natural sciences and social sciences, driving subscription and open-access publishing fees above levels that can be sustainably maintained by publicly funded universities, libraries, and research institutions worldwide. About a third of the costs paid for publishing papers is profit for these dominant publishers' shareholders, and about half of them covers costs to keep the system running, including lobbying, marketing fees, and paywalls. The paywalls in turn restrict access of scientific outputs, preventing them from being freely shared with the public and other researchers. Thus, money that the public is told goes into science is actually being funneled away from it, or used to limit access to it. Alternatives to this model exist and have increased in popularity in recent years, including diamond open-access journals and community-driven recommendation models. These are free of charge for authors and minimize costs for institutions and agencies, while making peer-reviewed scientific results publicly accessible. However, for-profit publishing agents have made change difficult, by co-opting open-access schemes and creating journal-driven incentives that prevent an effective collective transition away from profiteering. Here, we give a brief overview of the current state of the academic publishing system, including its most important systemic problems. We then describe alternative systems. We explain the reasons why the move toward them can be perceived as costly to individual researchers, and we demystify common roadblocks to change. Finally, in view of the above, we provide a set of guidelines and recommendations that academics at all levels can implement, in order to enable a more rapid and effective transition toward ethical publishing.
Published: 2022

20. Agronomic biofortification of cowpea with zinc: variation in primary metabolism responses and grain nutritional quality among 29 diverse genotypes

Author: SILVA, V. M., NARDELI, A. J., MENDES, N. A. de C., ROCHA, M. de M., WILSON, L., YOUNG, S. D., BROADLEY, M. R., WHITE, P. J., REIS, A. R. dos, VINÍCIUS MARTINS SILVA, UNESP, Jaboticabal, SP, Brazil, ANA JÚLIA NARDELI, UNESP, Jaboticabal, SP, Brazil, NANDHARA ANGÉLICA DE CARVALHO MENDES, UNESP, Tupã, SP, Brazil, MAURISRAEL DE MOURA ROCHA, CPAMN, LOLITA WILSON, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, SCOTT D. YOUNG, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, MARTIN R. BROADLEY, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, PHILIP J. WHITE, The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK, and ANDRÉ RODRIGUES DOS REIS, UNESP, Jaboticabal, SP, Brazil.
Subjects: Ureides, Phytic acid, Açúcar, Aminoácido, Vigna Unguiculata, Proteína, Amino acids
Abstract: Dietary zinc (Zn) deficiency is widespread globally, and is particularly prevalent in low- and middle-income countries (LMICs). Cowpea (Vigna unguiculata (L.) Walp) is consumed widely in LMICs due to its high protein content, and has potential for use in agronomic biofortification strategies using Zn. This study aimed to evaluate the effect of Zn biofortification on grain nutritional quality of 29 cowpea genotypes. Zn application did not increase cowpea yield. In 11 genotypes sucrose concentration, in 12 genotypes total sugar concentration, and in 27 genotypes storage protein concentration increased in response to Zn supply. Fifteen genotypes had lower concentrations of amino acids under Zn application, which are likely to have been converted into storage proteins, mostly comprised of albumin. Phytic acid (PA) concentration and PA/Zn molar ratio were decreased under Zn application. Six genotypes increased shoot ureides concentration in response to Zn fertilization, indicating potential improvements to biological nitrogen fixation. This study provides valuable information on the potential for Zn application to increase cowpea grain nutritional quality by increasing Zn and soluble storage protein and decreasing PA concentration. These results might be useful for future breeding programs aiming to increase cowpea grain Zn concentrations through biofortification. Made available in DSpace on 2021-05-18T14:27:23Z (GMT). No. of bitstreams: 1 Agronomic1-s2.0-S0981942821000875-main.pdf: 8793653 bytes, checksum: 80493066af6e43a23e3a891bb7f58d2d (MD5) Previous issue date: 2021
Published: 2021

21. Application of sodium selenate to cowpea (Vigna unguiculata L.) increases shoot and grain Se partitioning with strong genotypic interactions

Author: SILVA, V. M., NARDELI, A. J., MENDES, N. A. C., ALCOCK, T. D., ROCHA, M. de M., PUTTI, F. F., WILSON, L., YOUNG, S. D., BROADLEY, M. R., WHITE, P. J., REIS, A. R. dos, VINÍCIUS MARTINS SILVA, UNESP, ANA JÚLIA NARDELI, UNESP, NANDHARA ANGELICA CARVALHO MENDES, UNESP, THOMAS D. ALCOCK, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, MAURISRAEL DE MOURA ROCHA, CPAMN, FERNANDO FERRARI PUTTI, UNESP, LOLITA WILSON, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, SCOTT D. YOUNG, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, MARTIN R. BROADLEY, School of Biosciences, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK, PHILIP J. WHITE, The James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK, and ANDRÉ RODRIGUES DOS REIS, UNESP.
Subjects: Qualidade do grão, Biofortificação, Selênio, Vigna Unguiculata, Selenito de sódio, Biofortification
Abstract: Backgorund: Cowpea is a crop widely used in developing countries due its rusticity. Besides its rich genotypic variability, most breeding programs do not explore its potential to improve elements uptake. Selenium (Se) is a scarce element in most soils, resulting in its deficiency being common in human diets. This study aimed to evaluate the interaction between biofortification with Se and genotypic variation in cowpea, on the concentrations of Se in roots, leaves + stem and grains. Made available in DSpace on 2021-05-19T14:25:54Z (GMT). No. of bitstreams: 1 Silva-et-al-2021.pdf: 3044737 bytes, checksum: 29458aeffe6c5df46b75531a42a63207 (MD5) Previous issue date: 2021
Published: 2021

22. Archaeometallurgical Investigations in Nakhchivan, Azerbaijan: What Does the Evidence from Late Chalcolithic Ovçular Tepesi Tell Us about the Beginning of Extractive Metallurgy?

Author: Catherine Marro, Michael Bode, Veli Bakhshaliyev, Andreas Hauptmann, Nicolas Gailhard, Archéologies et Sciences de l'Antiquité (ArScAn), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), ARC Centre of Excellence for Environmental Decisions (ARC CEED), School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Royal Melbourne Institute of Technology University (RMIT University)-University of Queensland [Brisbane]-Australian National University (ANU)-The University of Western Australia (UWA), Deutsches Bergbau-Museum Bochum (DBM), DBM, ARCHEORIENT - Environnements et sociétés de l'Orient ancien (Archéorient), Université Lumière - Lyon 2 (UL2)-Centre National de la Recherche Scientifique (CNRS), ANR-12-FRAL-0002,MINES,Du sel, du cuivre et de l'or : origines et développement des industries minières au Caucase(2012), The University of Western Australia (UWA)-Australian National University (ANU)-University of Queensland [Brisbane]-Royal Melbourne Institute of Technology University (RMIT University)-School of BioSciences [Melbourne], University of Melbourne-University of Melbourne, and Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Institut national de recherches archéologiques préventives (Inrap)-Centre National de la Recherche Scientifique (CNRS)
Subjects: 010506 paleontology, Archeology, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, 060102 archaeology, 06 humanities and the arts, Chalcolithic, computer.file_format, Extractive metallurgy, 01 natural sciences, Copper ore, Archaeology, JAR, Assemblage (archaeology), 0601 history and archaeology, computer, Geology, 0105 earth and related environmental sciences
Abstract: International audience; The Late Chalcolithic (4400–3950 b.c.) occupation levels from Ovçular Tepesi have yielded a significant assemblage of copper objects and remains of copper production. Together with ore finds, two fragments of nozzle, crucible remains, and a number of small metal artifacts, this assemblage includes the unexpected discovery of three copper axes in an infant burial jar. These axes are the earliest examples of large copper tools known to date in southwestern Asia, whether it is in the Caucasus, Iran, or the Anatolian highlands. More importantly, the fact that these objects were locally produced suggests that significant metallurgical activities were being carried out at Ovçular as early as the second half of the 5th millennium b.c. After presenting the evidence from Ovçular Tepesi, this paper will proceed to a reassessment of the available archaeological and geochemical data concerning the emergence of extractive metallurgy in the southern Caucasus. © 2017, © Trustees of Boston University 2017.
Published: 2017

23. A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk

Author: Berthenet, Elvire, Yahara, Koji, Thorell, Kaisa, Pascoe, Ben, Meric, Guillaume, Mikhail, Jane, Engstrand, Lars, Enroth, Helena, Burette, Alain, Megraud, Francis, Varon, Christine, Atherton, John, Smith, Sinead, Wilkinson, Thomas, Hitchings, Matthew, Falush, Daniel, Sheppard, Samuel, Bodescot, Myriam, Microbiology and Infectious Disease Group [Swansea, Royaume-Uni], Swansea University Medical School [Swansea, Royaume-Uni], Swansea University-Swansea University, Antimicrobial Resistance Research Centre [Toyama, Japon], National Institute of Infectious Diseases [Toyama, Japon], Department of Microbiology, Tumour and Cell Biology [Stockholm, Suède], Karolinska Institutet [Stockholm], University of Bath [Bath], School of Biosciences [Cardiff, Royaume-Uni], College of Biomedical and Life Sciences [Cardiff, Royaume-Uni], Cardiff University-Cardiff University, Systems Biology Research Group [Skövde, Suède], School of Biosciences [Skövde, Suède], University of Skövde [Sweden]-University of Skövde [Sweden], Department of Gastroenterology [Bruxelles, Belgique], Centre Hospitalier Interrégional Edith Cavell (CHIREC), Laboratoire de Bactériologie [Bordeaux], Centre National de Référence des Campylobacters et des Hélicobacters [Bordeaux] (CNRCH), Bordeaux Research In Translational Oncology [Bordeaux] (BaRITOn), Université de Bordeaux (UB)-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), Nottingham Digestive Diseases Centre [Nottingham, Royaume-Uni], University of Nottingham, UK (UON), Department of Clinical Medicine [Dublin, Irlande], School of Medicine [Dublin], Trinity College Dublin-Trinity College Dublin, Elvire Berthenet is funded by a grant from HCRW. Sam K Sheppard is a principal investigator for the MRC CLIMB consortium (MR/L015080/1) and Daniel Falush is supported by a fellowship as part of MRC CLIMB (MR/M501608/1). S.K.S. is also funded by MRC grant G0801929, BBSRC grant BB/I02464X/1 and the Wellcome Trust. Jane Mikhail received funding from MITReG, St David’s Medical Foundation and ABMUHB., Department of Biology and Biochemistry [Bath, Royaume-Uni], Milner Centre for Evolution [Bath, Royaume-Uni], and University of Bath [Bath]-University of Bath [Bath]
Subjects: Risk, Metaplasia, Helicobacter pylori, Virulence Factors, Genetic Variation, [SDV.CAN]Life Sciences [q-bio]/Cancer, Polymorphism, Single Nucleotide, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Microbiology in the medical area, [SDV.CAN] Life Sciences [q-bio]/Cancer, lcsh:Biology (General), Stomach Neoplasms, Gastritis, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Mikrobiologi inom det medicinska området, Humans, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], GWAS, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Gastric cancer, lcsh:QH301-705.5, Genome, Bacterial, Research Article, Genome-Wide Association Study
Abstract: Background Helicobacter pylori are stomach-dwelling bacteria that are present in about 50% of the global population. Infection is asymptomatic in most cases, but it has been associated with gastritis, gastric ulcers and gastric cancer. Epidemiological evidence shows that progression to cancer depends upon the host and pathogen factors, but questions remain about why cancer phenotypes develop in a minority of infected people. Here, we use comparative genomics approaches to understand how genetic variation amongst bacterial strains influences disease progression. Results We performed a genome-wide association study (GWAS) on 173 H. pylori isolates from the European population (hpEurope) with known disease aetiology, including 49 from individuals with gastric cancer. We identified SNPs and genes that differed in frequency between isolates from patients with gastric cancer and those with gastritis. The gastric cancer phenotype was associated with the presence of babA and genes in the cag pathogenicity island, one of the major virulence determinants of H. pylori, as well as non-synonymous variations in several less well-studied genes. We devised a simple risk score based on the risk level of associated elements present, which has the potential to identify strains that are likely to cause cancer but will require refinement and validation. Conclusion There are a number of challenges to applying GWAS to bacterial infections, including the difficulty of obtaining matched controls, multiple strain colonization and the possibility that causative strains may not be present when disease is detected. Our results demonstrate that bacterial factors have a sufficiently strong influence on disease progression that even a small-scale GWAS can identify them. Therefore, H. pylori GWAS can elucidate mechanistic pathways to disease and guide clinical treatment options, including for asymptomatic carriers. Electronic supplementary material The online version of this article (10.1186/s12915-018-0550-3) contains supplementary material, which is available to authorized users.
Published: 2018

24. Advancing marine conservation in European and contiguous seas with the MarCons Action

Author: Athanasios Evagelopoulos, Vanessa Stelzenmüller, Paolo G. Albano, Stelios Katsanevakis, Ruth Brennan, Draško Holcer, Peter J.S. Jones, Gidon Winters, José Antonio García-Charton, Sylvaine Giakoumi, Thomas Kirk Sørensen, Robert J. Smith, Ioannis N. Vogiatzakis, Fiorenza Micheli, Vesna Mačić, Giovanni D’Anna, Fabio Pranovi, Noam Levin, Marta Coll, Michelle E. Portman, David Goldsborough, Carlo Pipitone, Alan Deidun, E. J. Milner-Gulland, Simonetta Fraschetti, Joachim Claudet, Carlos Jiménez, Georg Martin, Antonios D. Mazaris, Dubravko Culibrk, Fabio Badalamenti, Bojan Lazar, Peter Mackelworth, Salit Kark, Gil Rilov, Department of Marine Sciences [Aegean], University of the Aegean, Blue World Institute of Marine Research and Conservation, Institut de Recherche pour le Développement (IRD [Nouvelle-Calédonie]), Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (DiSTeBA), Università del Salento [Lecce], University of Montenegro (UCG), ARC Centre of Excellence for Environmental Decisions (ARC CEED), The University of Western Australia (UWA)-Australian National University (ANU)-University of Queensland [Brisbane]-Royal Melbourne Institute of Technology University (RMIT University)-School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, iThemba Laboratory for Accelerator Based Science, Department of Geography, The Hebrew University of Jerusalem (HUJ), Department of Palaeontology, Universität Wien, Laboratorio di Ecologia (CNR-IAMC), CNRS-IAMC, Department of Mathematics (TECHNION), Technion - Israel Institute of Technology [Haifa], Centre de recherches insulaires et observatoire de l'environnement (CRIOBE), Université de Perpignan Via Domitia (UPVD)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Excellence CORAIL (LabEX CORAIL), Université des Antilles (UA)-Institut d'écologie et environnement-Université de la Nouvelle-Calédonie (UNC)-Université de la Polynésie Française (UPF)-Université de La Réunion (UR)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École des hautes études en sciences sociales (EHESS)-Université des Antilles et de la Guyane (UAG)-Institut de Recherche pour le Développement (IRD), Faculty of Technical Sciences [Novi Sad], University of Novi Sad, CNR Institute for Coastal Marine Environment (IAMC), Consiglio Nazionale delle Ricerche (CNR), Department of Geosciences, University of Malta [Malta], Departamento Ecologia e Hidrologia, Universidad de Murcia, Van Hall Larenstein University of Applied Sciences, Wageningen University and Research [Wageningen] (WUR), Van Hall Larenstein, Aalen University of Applied Sciences, Croatian Natural History Museum, Department of Ecology, Systematics and Evolution. The Institute of Live Sciences, Aarhus University [Aarhus], Institute of Earth Sciences and Moshe Shilo Centre for Biogeochemistry, Science et Ingénierie des Matériaux et Procédés (SIMaP ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Department of Ecology, School of Biology, Hopkins Marine Station [Stanford], Stanford University, Departement of Life sciences, Imperial College London, Institute of Surveying, Remote Sensing & Land Information (IVFL), Universität für Bodenkultur Wien [Vienne, Autriche] (BOKU), Environmental Sciences Department, University of Ca’ Foscari [Venice, Italy], CSIR National Institute of Oceanography [India] (NIO), Durrell Institute of Conservation and Ecology, University of Kent [Canterbury], Thünen-Institute of Sea Fisheries, School of Pure and Applied Sciences, Dead Sea-Arava Science Center (DSASC), School of BioSciences [Melbourne], University of Melbourne-University of Melbourne-Royal Melbourne Institute of Technology University (RMIT University)-University of Queensland [Brisbane]-Australian National University (ANU)-The University of Western Australia (UWA), Institut de Recherche pour le Développement (IRD)-Université des Antilles et de la Guyane (UAG)-École des hautes études en sciences sociales (EHESS)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de La Réunion (UR)-Université de la Polynésie Française (UPF)-Université de la Nouvelle-Calédonie (UNC)-Institut d'écologie et environnement-Université des Antilles (UA), Institute of marine biology, iThemba LABS [National Research Foundation], National Research Foundation [South Africa] (NRF), Université de Perpignan Via Domitia (UPVD)-École Pratique des Hautes Études (EPHE), Institut de Recherche pour le Développement (IRD)-Université des Antilles et de la Guyane (UAG)-École des hautes études en sciences sociales (EHESS)-École Pratique des Hautes Études (EPHE), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), Universität für Bodenkultur Wien = University of Natural Resources and Life [Vienne, Autriche] (BOKU), and European Cooperation in Science and Technology
Subjects: 0106 biological sciences, Marine conservation, marine biodiversity, [SDE.MCG]Environmental Sciences/Global Changes, Maritime spatial planning, biological invasions, Biodiversity, QH75, 010603 evolutionary biology, 01 natural sciences, Ecosystem services, Integrated conservation planning, Marine resources conservation -- Law and legislation -- European Union countries, Biological invasions -- Europe, media_common.cataloged_instance, Marine ecosystem, 14. Life underwater, Maritime law -- Europe, European union, Biological invasions, Marine biodiversity, lcsh:Science, marine governance, Spatial planning, Cumulative impacts, media_common, maritime spatial planning, [SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere, business.industry, [SDE.IE]Environmental Sciences/Environmental Engineering, 010604 marine biology & hydrobiology, Environmental resource management, General Medicine, 15. Life on land, Marine biodiversity -- Europe, 13. Climate action, Sustainability, Marine governance, Marine protected area, lcsh:Q, Business, cumulative impacts, [SDE.BE]Environmental Sciences/Biodiversity and Ecology
Abstract: Katsanevakis, Stelios ... et al.-- 16 pages, 2 figures, Cumulative human impacts have led to the degradation of marine ecosystems and the decline of biodiversity in the European and contiguous seas. Effective conservation measures are urgently needed to reverse these trends. Conservation must entail societal choices, underpinned by human values and worldviews that differ between the countries bordering these seas. Social, economic and political heterogeneity adds to the challenge of balancing conservation with sustainable use of the seas. Comprehensive macro-regional coordination is needed to ensure effective conservation of marine ecosystems and biodiversity of this region. Under the European Union Horizon 2020 framework programme, the MarCons COST action aims to promote collaborative research to support marine management, conservation planning and policy development. This will be achieved by developing novel methods and tools to close knowledge gaps and advance marine conservation science. This action will provide support for the development of macro-regional and national policies through six key actions: to develop tools to analyse cumulative human impacts; to identify critical scientific and technical gaps in conservation efforts; to improve the resilience of the marine environment to global change and biological invasions; to develop frameworks for integrated conservation planning across terrestrial, freshwater, and marine environments; to coordinate marine conservation policy across national boundaries; and to identify effective governance approaches for marine protected area management. Achieving the objectives of these actions will facilitate the integration of marine conservation policy into macro-regional maritime spatial planning agendas for the European and contiguous seas, thereby offsetting the loss of biodiversity and ecosystem services in this region, This article is based upon work from COST (European Cooperation in Science and Technology) Action 15121 ‘Advancing marine conservation in the European and contiguous seas (MarCons) - supported by the Horizon 2020 framework programme for research and innovation
Published: 2017

25. The complete mitochondrial DNA sequence of the pantropical earthworm Pontoscolex corethrurus (Rhinodrilidae, Clitellata): mitogenome characterization and phylogenetic positioning

Author: CONRADO, A. C., ARRUDA, H., STANTON, D. W. S., JAMES, S. W., KILLE, P., BROWN, G. G., SILVA, E. da, DUPONT, E., TAHERI, S., MORGAN, A. J., SIMÕES, N., RODRIGUES, A., MONTIEL, R., CUNHA, L., Ana C. Conrado, UFPR, Hugo Arruda, Departamento de Biologia, Universidade dos Açores, Ponta Delgada, Portugal, David W.G. Stanton, Cardiff School of Biosciences, Cardiff University, Museum Avenue, Samuel W. James, University of Management, Sustainable Living Dept., Fairfield, Peter Kille, Cardiff School of Biosciences, Cardiff University, Museum Avenue, GEORGE GARDNER BROWN, CNPF, Elodie da Silva, Bolsista da Embrapa Florestas, Lise Dupont, Université Paris Est Créteil, Institut d’écologie et des sciences, Shabnam Taheri, Université Paris Est Créteil, Institut d’écologie et des sciences, Andrew J. Morgan, Cardiff School of Biosciences, Cardiff University, Museum Avenue, Nelson Simões, Departamento de Biologia, Universidade dos Açores, Ponta Delgada, Portugal, Universidade dos Açores, Ponta Delgada, Portugal. (CVARG), Rafael Montiel, Laboratorio Nacional de Genómica para la Biodiversidad, Unidad de Genómica Avanzada, México, and Luis Cunha, Bolsista da Embrapa Florestas.
Subjects: Pontoscolex corethrurus, Minhoca, Mitochondrial genome, Peregrine species, Mitocôndria, Azores, Açores, Earthworm, Rhinodrilidae, Genoma, Mitochondria
Abstract: Pontoscolex corethrurus (Müller, 1857) plays an important role in tropical soil ecosystems and has been widely used as an animal model for a large variety of ecological studies, in particular due to its common presence and generally high abundance in human-disturbed tropical soils. In this study we describe the complete mitochondrial genome of the peregrine earthworm P. corethrurus. This is the first record of a mitochondrial genome within the Rhinodrilidae family. Its mitochondrial genome is 14 835 bp in length containing 37 genes (13 protein-coding genes (PCG), 2 rRNA genes and 22 tRNA genes). It has the same gene content and structure as in other sequenced earthworms, but unusual among invertebrates it has several overlapping open reading frames. All genes are encoded on the same strand. Most of the PCGs use ATG as the start codon except for ND3, which uses GTG as the start codon. The A+T content of the mitochondrial genome is 59.9% (31.8% A, 28.1% T, 14.6% G, and 25.6% for C). The annotated genome sequence has been deposited in GenBank under the accession number KT988053. Made available in DSpace on 2017-09-30T10:26:30Z (GMT). No. of bitstreams: 1 2017G.BrownZookeysTheComplete.pdf: 610045 bytes, checksum: 662e5d94944a5f2f6298e53ca80a3553 (MD5) Previous issue date: 2017-09-28 Publicado na PeerJ Preprints em 3 mar. 2017.
Published: 2017

26. Regulation of cell wall genes in response to DEFECTIVE KERNEL1 (DEK1)-induced cell wall changes

Author: Antony Bacic, Dhika Amanda, Monika S. Doblin, Gwyneth C. Ingram, Roberta Galletti, Kim L. Johnson, Max Planck Institute for Plant Breeding Research (MPIPZ), ARC Centre of Excellence in Plant Cell Walls, University of Queensland [Brisbane]-School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-University of Adelaide, Institut National de la Recherche Agronomique (INRA), Reproduction et développement des plantes (RDP), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-École normale supérieure - Lyon (ENS Lyon), Australian Research Council Center of Excellence in Plant cell walls CE1101007, University of Adelaide-University of Queensland [Brisbane]-School of BioSciences [Melbourne], University of Melbourne-University of Melbourne, École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)
Subjects: 0106 biological sciences, 0301 basic medicine, Short Communication, [SDV]Life Sciences [q-bio], Cell, Arabidopsis, Plant Science, Biology, Genes, Plant, 01 natural sciences, 03 medical and health sciences, Expansin, Gene Expression Regulation, Plant, Genes, Reporter, epidermis, Gene expression, medicine, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Transcription factor, Glucuronidase, Regulation of gene expression, Epidermis (botany), Arabidopsis Proteins, Calpain, cell wall integrity, Cell biology, 030104 developmental biology, medicine.anatomical_structure, biology.protein, cell wall, Signal transduction, DEFECTIVE KERNEL1, signaling, 010606 plant biology & botany
Abstract: Epub 2017 Jul 10; International audience; Defective Kernel1 (DEK1) is a plant-specific calpain involved in epidermis specification and maintenance. DEK1 regulation of the epidermal cell wall is proposed to be key to ensure tissue integrity and coordinated growth. Changes in the expression of DEK1 are correlated with changes in the expression of cell wallrelated genes. For example, we have found that Lipid transfer protein 3 (LTP3), EXPANSIN 11 (EXP11), and an AP2 transcription factor (AP2TF) are misexpressed in plants with constitutively altered levels of DEK1 activity. RT-qPCR studies show that LTP3 and AP2TF may respond to a DEK1-generated signal whereas EXP11 is not altered immediately after dexamethasone induction of CALPAIN suggesting it is not in the direct signaling pathway downstream of DEK1. Our data suggest these genes are regulated by a feedback mechanism in response to DEK1-induced changes in the cell wall, and contribute to the phenotypes seen in plants with altered DEK1 expression.
Published: 2017

27. The LOFT mission concept: a status update

Author: Feroci, M, Bozzo, E, Brandt, S, Hernanz, M, Van Der Klis, M, Liu, L, Orleanski, P, Pohl, M, Santangelo, A, Schanne, S, Stella, L, Takahashi, T, Tamura, H, Watts, A, Wilms, J, Zane, S, Zhang, S, Bhattacharyya, S, Agudo, I, Ahangarianabhari, M, Albertus, C, Alford, M, Alpar, A, Altamirano, D, Alvarez, L, Amati, L, Amoros, C, Andersson, N, Antonelli, A, Argan, A, Artigue, R, Artigues, B, Atteia, J, Azzarello, P, Bakala, P, Ballantyne, Dr, Baldazzi, G, Baldo, M, Balman, S, Barbera, M, Van Baren, C, Barret, D, Baykal, A, Begelman, M, Behar, E, Behar, O, Belloni, T, Bellutti, P, Bernardini, F, Bertuccio, G, Bianchi, S, Bianchini, A, Binko, P, Blay, P, Bocchino, F, Bode, M, Bodin, P, Bombaci, I, Bonnet Bidaud, J, Borghi, G, Boutloukos, S, Bouyjou, F, Bradley, L, Braga, J, Briggs, Ms, Brown, E, Buballa, M, Bucciantini, N, Burderi, L, Burgay, M, Bursa, M, Budtz-Jorgensen, C, Cackett, E, Cadoux, Fr, Cais, P, Caliandro, Ga, Campana, R, Campana, S, Cao, X, Capitanio, F, Casares, J, Casella, P, Castro-Tirado, Aj, Cavazzuti, E, Cavechi, Y, Celestin, S, Cerda-Duran, P, Chakrabarty, D, Chamel, N, Chateau, F, Chen, C, Chen, Y, Chenevez, J, Chernyakova, M, Coker, J, Cole, R, Collura, A, Coriat, M, Cornelisse, R, Costamante, L, Cros, A, Cui, W, Cumming, A, Cusumano, G, Czerny, B, D'Ai, A, D'Ammando, F, D'Elia, V, Dai, Z, Del Monte, E, De Luca, A, De Martino, D, Dercksen, Jpc, De Pasquale, M, De Rosa, A, Del Santo, M, Di Cosimo, S, Degenaar, N, Den Herder, Jw, Diebold, S, Di Salvo, T, Dong, Y, Donnarumma, I, Doroshenko, V, Doyle, G, Drake, Sa, Durant, M, Emmanoulopoulos, D, Enoto, T, Erkut, Mh, Esposito, P, Evangelista, Y, Fabian, A, Falanga, M, Favre, Y, Feldman, C, Fender, R, Feng, H, Ferrari, V, Ferrigno, C, Ficorella, F, Finger, M, Finger, Mh, Fraser, Gw, Frericks, M, Fullekrug, M, Fuschino, F, Gabler, M, Galloway, Dk, Galvez Sanchez, Jl, Gandhi, P, Gao, Z, Garcia-Berro, E, Gendre, B, Gevin, O, Gezari, S, Giles, Ab, Gilfanov, M, Giommi, P, Giovannini, G, Giroletti, M, Gogus, E, Goldwurm, A, Goluchova, K, Gotz, D, Gou, L, Gouiffes, C, Grandi, P, Grassi, M, Greiner, J, Grinberg, V, Groot, P, Gschwender, M, Gualtieri, L, Guedel, M, Guidorzi, C, Guy, L, Haas, D, Haensel, P, Hailey, M, Hamuguchi, K, Hansen, F, Hartmann, Dh, Haswell, Ca, Hebeler, K, Heger, A, Hempel, M, Hermsen, W, Homan, J, Hornstrup, A, Hudec, R, Huovelin, J, Huppenkothen, D, Inam, Sc, Ingram, A, In'Tzand, Jjm, Israel, G, Iwasawa, K, Izzo, L, Jacobs, Hm, Jetter, F, Johannsen, T, Jenke, Pa, Jonker, P, Jose, J, Kaaret, P, Kalamkar, M, Kalemci, E, Kanbach, G, Karas, V, Karelin, D, Kataria, D, Keek, L, Kennedy, T, Klochkov, D, Kluzniak, W, Koerding, E, Kokkotas, K, Komossa, S, Korpela, S, Kouveliotou, C, Kowalski, Af, Kreykenbohm, I, Kuiper, Lm, Kunneriath, D, Kurkela, A, Kuvvetli, I, La Franca, F, Labanti, C, Lai, D, Lamb, Fk, Lachaud, C, Laubert, Pp, Lebrun, F, Li, X, Liang, E, Limousin, O, Lin, D, Linares, M, Linder, D, Lodato, G, Longo, F, Lu, F, Lund, N, Maccarone, Tj, Macera, D, Maestre, S, Mahmoodifar, S, Maier, D, Malcovati, P, Malzac, J, Malone, C, Mandel, I, Mangano, V, Manousakis, A, Marelli, M, Margueron, J, Marisaldi, M, Markoff, Sb, Markowitz, A, Marinucci, A, Martindale, A, Martinez, G, Mchardy, Im, Medina-Tanco, G, Mehdipour, M, Melatos, A, Mendez, M, Mereghetti, S, Migliari, S, Mignani, R, Michalska, M, Mihara, T, Miller, Mc, Miller, Jm, Mineo, T, Miniutti, G, Morsink, S, Motch, C, Motta, S, Mouchet, M, Mouret, G, Mulacova, J, Muleri, F, Munoz-Darias, T, Negueruela, I, Neilsen, J, Neubert, T, Norton, Aj, Nowak, M, Nucita, A, O'Brien, P, Oertel, M, Olsen, Peh, Orienti, M, Orio, M, Orlandini, M, Osborne, Jp, Osten, R, Ozel, F, Pacciani, L, Paerels, F, Paltani, S, Paolillo, M, Papadakis, I, Papitto, A, Paragi, Z, Paredes, Jm, Patruno, A, Paul, B, Pederiva, F, Perinati, E, Pellizzoni, A, Penacchioni, Av, Peretz, U, Perez, Ma, Perez-Torres, M, Peterson, Bm, Petracek, V, Picciotto, A, Piemonte, C, Pittori, C, Pons, J, Portell, J, Possenti, A, Postnov, K, Poutanen, J, Prakash, M, Prandoni, I, Le Provost, H, Psaltis, D, Pye, J, Qu, J, Rambaud, D, Ramon, P, Ramsay, G, Rapisarda, M, Rachevski, A, Rashevskaya, I, Ray, Ps, Rea, N, Reddy, S, Reig, P, Reina Aranda, M, Remillard, R, Reynolds, C, Rezzolla, L, Ribo, M, De La Rie, R, Riggio, A, Rios, A, Rischke, Dh, Rodriguez-Gil, P, Rodriguez, J, Rohlfs, R, Romano, P, Rossi, Emr, Rozanska, A, Rousseau, A, Rudak, B, Russell, Dm, Ryde, F, Sabau-Graziati, L, Sakamoto, T, Sala, G, Salvaterra, R, Salvetti, D, Sanna, A, Sandberg, J, Savolainen, T, Scaringi, S, Schaffner-Bielich, J, Schatz, H, Schee, J, Schmid, C, Serino, M, Shakura, N, Shore, S, Schnittman, Jd, Schneider, R, Schwenk, A, Schwope, Ad, Sedrakian, A, Seyler, J, Shearer, A, Slowikowska, A, Sims, M, Smith, A, Smith, Dm, Smith, Pj, Sobolewska, M, Sochora, V, Soffitta, P, Soleri, P, Song, L, Spencer, A, Stamerra, A, Stappers, B, Staubert, R, Steiner, Aw, Stergioulas, N, Stevens, Al, Stratta, G, Strohmayer, Te, Stuchlik, Z, Suchy, S, Suleimanov, V, Tamburini, F, Tauris, T, Tavecchio, F, Tenzer, C, Thielemann, Fk, Tiengo, A, Tolos, L, Tombesi, F, Tomsick, J, Torok, G, Torrejon, Jm, Torres, Df, Torresi, E, Tramacere, A, Traulsen, I, Trois, A, Turolla, R, Turriziani, S, Typel, S, Uter, P, Uttley, P, Vacchi, A, Varniere, P, Vaughan, S, Vercellone, S, Vietri, M, Vincent, Fh, Vrba, V, Walton, D, Wang, J, Wang, Z, Watanabe, S, Wawrzaszek, R, Webb, N, Weinberg, N, Wende, H, Wheatley, P, Wijers, R, Wijnands, R, Wille, M, Wilson-Hodge, Ca, Winter, B, Walk, Sj, Wood, K, Woosley, Se, Wu, X, Xiao, L, Xu, R, Yu, W, Yuan, F, Yuan, W, Yuan, Y, Zampa, G, Zampa, N, Zampieri, L, Zdunik, L, Zdziarski, A, Zech, A, Zhang, B, Zhang, C, Zingale, M, Zorzi, N, Zwart, F, High Energy Astrophys. & Astropart. Phys (API, FNWI), ISDC Data Centre for Astrophysics, Université de Genève = University of Geneva (UNIGE), Icahn School of Medicine at Mount Sinai [New York] (MSSM), Rutgers, The State University of New Jersey [New Brunswick] (RU), Rutgers University System (Rutgers), Institut für Astronomie und Astrophysik [Tübingen] (IAAT), Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Dipartimento di Scienze e Tecnologie Chimiche, Università degli Studi di Roma Tor Vergata [Roma], Graduate School of the Natural Science and Technology [Kanazawa], Kanazawa University (KU), Astronomical Institute Anton Pannekoek (AI PANNEKOEK), University of Amsterdam [Amsterdam] (UvA), Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Tampere University of Technology [Tampere] (TUT), University of Maryland [College Park], University of Maryland System, Department of Biological Sciences [Mississippi], University of Southern Mississippi (USM), School of Physics and Astronomy [Southampton], University of Southampton, Istituto di Astrofisica Spaziale e Fisica Cosmica - Milano (IASF-MI), Istituto Nazionale di Astrofisica (INAF), Università di Roma La Sapienza, Università di Roma Tor Vergata, Istituto di Astrofisica e Planetologia Spaziali - INAF (IAPS), Laboratoire d'Astrophysique de l'Observatoire Midi-Pyrénées (LATT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Swedish Institute of Space Physics [Uppsala] (IRF), INAF - Osservatorio Astronomico di Brera (OAB), Department of Computer Sciences [Scheffield], University of Sheffield [Sheffield], Colgate University, Bibliothèque nationale de France (BnF), Istituto di Astrofisica Spaziale e Fisica cosmica - Palermo (IASF-Pa), ARC Centre of Excellence for Environmental Decisions (ARC CEED), The University of Western Australia (UWA)-Australian National University (ANU)-University of Queensland [Brisbane]-Royal Melbourne Institute of Technology University (RMIT University)-School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, ARC Centre of Excellence for Coral Reef Studies (CoralCoE), James Cook University (JCU), Lund University [Lund], Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de synthèse organique (DCSO), École polytechnique (X)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Alabama at Birmingham [ Birmingham] (UAB), INAF - Osservatorio Astronomico di Cagliari (OAC), ELECTRONIQUE 2016, Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Théorique et Modèles Statistiques (LPTMS), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), School of Geosciences, Monash University [Clayton], Laboratoire de Physique et Chimie de l'Environnement et de l'Espace (LPC2E), Observatoire des Sciences de l'Univers en région Centre (OSUC), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Université libre de Bruxelles (ULB), National Oceanography Centre [Southampton] (NOC), Dublin Institute for Advanced Studies (DIAS), Dublin City University [Dublin] (DCU), Mullard Space Science Laboratory (MSSL), University College of London [London] (UCL), Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Chinese Academy of Sciences [Beijing] (CAS), Laboratoire Univers et Théories (LUTH (UMR_8102)), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), China Information Technology Security Evaluation Center (CNITSEC), Department of Applied Mathematics and Computer Science [Lyngby] (DTU Compute), Danmarks Tekniske Universitet = Technical University of Denmark (DTU), PCAS, Anton Pannekoek Institute for Astronomy, Institute of Astronomy [Cambridge], University of Cambridge [UK] (CAM), International Space Science Institute [Bern] (ISSI), Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), CALVIN research group [Edinburgh], Institute of Perception, Action and Behaviour (IPAB), University of Edinburgh-University of Edinburgh, Department of Electronics and Electrical Engineering [Bath], University of Bath [Bath], United States Geological Survey [Reston] (USGS), Sr. PLM Consultant, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Dept Ind Engn & Informat Techonolgy, Università degli studi di Trieste = University of Trieste, Max-Planck-Institut für Extraterrestrische Physik (MPE), MIT Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology (MIT), Institut de Physique du Globe de Paris (IPGP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Matériaux, ingénierie et science [Villeurbanne] (MATEIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Wisconsin Regional Primate Research Center, University of Wisconsin-Madison, SRON Netherlands Institute for Space Research (SRON), Opole University of Technology, University of Technology (Opole), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Department of Astrophysics [Nijmegen], Institute for Mathematics, Astrophysics and Particle Physics (IMAPP), Radboud University [Nijmegen]-Radboud University [Nijmegen], Radboud University [Nijmegen], NASA Goddard Space Flight Center (GSFC), Dept Fis Aplicada, Universidad de Granada = University of Granada (UGR), Victoria University [Melbourne], The Hong Kong Polytechnic University [Hong Kong] (POLYU), Chinese Academy of Sciences [Changchun Branch] (CAS), Department of Physics, Chemistry and Biology [Linköping] (IFM), Linköping University (LIU), Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Erlangen Centre for Astroparticle Physics (ECAP), Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Centre de recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institute of Astronomy, University of Zielona Góra, Department of Electronics and Computer Systems, Takushoku University, Instituto Nacional de Pesquisas da Amazônia (INPA), Università degli studi di Catania = University of Catania (Unict), Centre d'Ecologie et des Sciences de la COnservation (CESCO), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Ecologie Alpine (LECA ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire de Physico-Chimie de l'Atmosphère (LPCA), Université du Littoral Côte d'Opale (ULCO)-Centre National de la Recherche Scientifique (CNRS), HEPL, Solar Physics, Stanford University, Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Space Telescope Science Institute (STSci), Dipartimento di Scienze Fisiche [Naples], University of Naples Federico II = Università degli studi di Napoli Federico II, Columbia University [New York], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Department of Anthropology [University of Arkansas], University of Arkansas [Fayetteville], Hu county ventre for disease control and prevention of Shaanxi province, Istituto Nazionale di Fisica Nucleare, Sezione di Trieste (INFN, Sezione di Trieste), Istituto Nazionale di Fisica Nucleare (INFN), Institut Jean le Rond d'Alembert (DALEMBERT), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Institut de Ciencies de l'Espai [Barcelona] (ICE-CSIC), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), University of Reading (UOR), Departamento de Matemática Aplicada, Universidade de Santiago de Compostela [Spain] (USC ), Osservatorio Astrofisico di Catania, Équipe Robotique et InteractionS (LAAS-RIS), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Centro Euro-Mediterraneo per i Cambiamenti Climatici [Bologna] (CMCC), Institut für Theoretische Physik, Universität Heidelberg [Heidelberg] = Heidelberg University, Augsburg Hospital, Leibniz-Institut für Astrophysik Potsdam (AIP), Daimler Chrysler AG (Daimler), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Montserrat Volcano Observatory (MVO), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), Jodrell Bank Centre for Astrophysics, University of Manchester [Manchester], FICLIT, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Max-Planck-Institut für Radioastronomie (MPIFR), Argelander-Institut für Astronomie (AlfA), Rheinische Friedrich-Wilhelms-Universität Bonn, Space Sciences Laboratory [Berkeley] (SSL), University of California [Berkeley] (UC Berkeley), University of California (UC)-University of California (UC), Christian-Albrechts-Universität zu Kiel (CAU), Dipartimento di Fisica e Astronomia 'Galileo Galilei', Università degli Studi di Padova = University of Padua (Unipd), APC - Gravitation (APC-Gravitation), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Cahill Center for Astronomy and Astrophysics, California Institute of Technology (CALTECH), Xinjiang Astronomical Observatory, Mitsubishi Electric Research Laboratories (MERL), Mitsubishi Research Institute, Inc., School of Urban and Regional Planning, University of Southern California (USC), National University of Defense Technology [China], Princeton University, Department of Microtechnology and Nanoscience (MC2), Chalmers University of Technology [Gothenburg, Sweden], Feroci, M., Bozzo, E., Brandt, S., Hernanz, M., van der Klis, M., Liu, L., Orleanski, P., Pohl, M., Santangelo, A., Schanne, S., Stella, L., Takahashi, T., Tamura, H., Watts, A., Wilms, J., Zane, S., Zhang, S., Bhattacharyya, S., Agudo, I., Ahangarianabhari, M., Albertus, C., Alford, M., Alpar, A., Altamirano, D., Alvarez, L., Amati, L., Amoros, C., Andersson, N., Antonelli, A., Argan, A., Artigue, R., Artigues, B., Atteia, J., Azzarello, P., Bakala, P., Ballantyne, D., Baldazzi, G., Baldo, M., Balman, S., Barbera, M., van Baren, C., Barret, D., Baykal, A., Begelman, M., Behar, E., Behar, O., Belloni, T., Bernardini, F., Bertuccio, G., Bianchi, S., Bianchini, A., Binko, P., Blay, P., Bocchino, F., Bode, M., Bodin, P., Bombaci, I., Bonnet Bidaud, J., Boutloukos, S., Bouyjou, F., Bradley, L., Braga, J., Briggs, M., Brown, E., Buballa, M., Bucciantini, N., Burderi, L., Burgay, M., Bursa, M., Budtz Jørgensen, C., Cackett, E., Cadoux, F., Cais, P., Caliandro, G., Campana, R., Campana, S., Cao, X., Capitanio, F., Casares, J., Casella, P., Castro Tirado, A., Cavazzuti, E., Cavechi, Y., Celestin, S., Cerda Duran, P., Chakrabarty, D., Chamel, N., Château, F., Chen, C., Chen, Y., Chenevez, J., Chernyakova, M., Coker, J., Cole, R., Collura, A., Coriat, M., Cornelisse, R., Costamante, L., Cros, A., Cui, W., Cumming, A., Cusumano, G., Czerny, B., D'Aì, A., D'Ammando, F., D'Elia, V., Dai, Z., Del Monte, E., De Luca, A., De Martino, D., Dercksen, J., De Pasquale, M., De Rosa, A., Del Santo, M., Di Cosimo, S., Degenaar, N., den Herder, J., Diebold, S., DI SALVO, T., Dong, Y., Donnarumma, I., Doroshenko, V., Doyle, G., Drake, S., Durant, M., Emmanoulopoulos, D., Enoto, T., Erkut, M., Esposito, P., Evangelista, Y., Fabian, A., Falanga, M., Favre, Y., Feldman, C., Fender, R., Feng, H., Ferrari, V., Ferrigno, C., Finger, M., Fraser, G., Frericks, M., Fullekrug, M., Fuschino, F., Gabler, M., Galloway, D., Gálvez Sanchez, J., Gandhi, P., Gao, Z., Garcia Berro, E., Gendre, B., Gevin, O., Gezari, S., Giles, A., Gilfanov, M., Giommi, P., Giovannini, G., Giroletti, M., Gogus, E., Goldwurm, A., Goluchová, K., Götz, D., Gou, L., Gouiffes, C., Grandi, P., Grassi, M., Greiner, J., Grinberg, V., Groot, P., Gschwender, M., Gualtieri, L., Guedel, M., Guidorzi, C., Guy, L., Haas, D., Haensel, P., Hailey, M., Hamuguchi, K., Hansen, F., Hartmann, D., Haswell, C., Hebeler, K., Heger, A., Hempel, M., Hermsen, W., Homan, J., Hornstrup, A., Hudec, R., Huovelin, J., Huppenkothen, D., Inam, S., Ingram, A., In't Zand, J., Israel, G., Iwasawa, K., Izzo, L., Jacobs, H., Jetter, F., Johannsen, T., Jenke, P., Jonker, P., Josè, J., Kaaret, P., Kalamkar, K., Kalemci, E., Kanbach, G., Karas, V., Karelin, D., Kataria, D., Keek, L., Kennedy, T., Klochkov, D., Kluzniak, W., Koerding, E., Kokkotas, K., Komossa, S., Korpela, S., Kouveliotou, C., Kowalski, A., Kreykenbohm, I., Kuiper, L., Kunneriath, D., Kurkela, A., Kuvvetli, I., La Franca, F., Labanti, C., Lai, D., Lamb, F., Lachaud, C., Laubert, P., Lebrun, F., Li, X., Liang, E., Limousin, O., Lin, D., Linares, M., Linder, D., Lodato, G., Longo, F., Lu, F., Lund, N., Maccarone, T., Macera, D., Maestre, S., Mahmoodifar, S., Maier, D., Malcovati, P., Malzac, J., Malone, C., Mandel, I., Mangano, V., Manousakis, A., Marelli, M., Margueron, J., Marisaldi, M., Markoff, S., Markowitz, A., Marinucci, A., Martindale, A., Martínez, G., Mchardy, I., Medina Tanco, G., Mehdipour, M., Melatos, A., Mendez, M., Mereghetti, S., Migliari, S., Mignani, R., Michalska, M., Mihara, T., Miller, M., Miller, J., Mineo, T., Miniutti, G., Morsink, S., Motch, C., Motta, S., Mouchet, M., Mouret, G., Mulačová, J., Muleri, F., Muñoz Darias, T., Negueruela, I., Neilsen, J., Neubert, T., Norton, A., Nowak, M., Nucita, A., O'Brien, P., Oertel, M., Olsen, P., Orienti, M., Orio, M., Orlandini, M., Osborne, J., Osten, R., Ozel, F., Pacciani, L., Paerels, F., Paltani, S., Paolillo, M., Papadakis, I., Papitto, A., Paragi, Z., Paredes, J., Patruno, A., Paul, B., Pederiva, F., Perinati, E., Pellizzoni, A., Penacchioni, A., Peretz, U., Perez, M., Perez Torres, M., Peterson, B., Petracek, V., Pittori, C., Pons, J., Portell, J., Possenti, A., Postnov, K., Poutanen, J., Prakash, M., Prandoni, I., Le Provost, H., Psaltis, D., Pye, J., Qu, J., Rambaud, D., Ramon, P., Ramsay, G., Rapisarda, M., Rashevski, A., Rashevskaya, I., Ray, P., Rea, N., Reddy, S., Reig, P., Reina Aranda, M., Remillard, R., Reynolds, C., Rezzolla, L., Ribo, M., de la Rie, R., Riggio, A., Rios, A., Rischke, D., Rodríguez Gil, P., Rodriguez, J., Rohlfs, R., Romano, P., Rossi, E., Rozanska, A., Rousseau, A., Rudak, B., Russell, D., Ryde, F., Sabau Graziati, L., Sakamoto, T., Sala, G., Salvaterra, R., Salvetti, D., Sanna, A., Sandberg, J., Savolainen, T., Scaringi, S., Schaffner Bielich, J., Schatz, H., Schee, J., Schmid, C., Serino, M., Shakura, N., Shore, S., Schnittman, J., Schneider, R., Schwenk, A., Schwope, A., Sedrakian, A., Seyler, J., Shearer, A., Slowikowska, A., Sims, M., Smith, A., Smith, D., Smith, P., Sobolewska, M., Sochora, V., Soffitta, P., Soleri, P., Song, L., Spencer, A., Stamerra, A., Stappers, B., Staubert, R., Steiner, A., Stergioulas, N., Stevens, A., Stratta, G., Strohmayer, T., Stuchlik, Z., Suchy, S., Suleimanov, V., Tamburini, F., Tauris, T., Tavecchio, F., Tenzer, C., Thielemann, F., Tiengo, A., Tolos, L., Tombesi, F., Tomsick, J., Torok, G., Torrejon, J., Torres, D., Torresi, E., Tramacere, A., Traulsen, I., Trois, A., Turolla, R., Turriziani, S., Typel, S., Uter, P., Uttley, P., Vacchi, A., Varniere, P., Vaughan, S., Vercellone, S., Vietri, M., Vincent, F., Vrba, V., Walton, D., Wang, J., Wang, Z., Watanabe, S., Wawrzaszek, R., Webb, N., Weinberg, N., Wende, H., Wheatley, P., Wijers, R., Wijnands, R., Wille, M., Wilson Hodge, C., Winter, B., Walk, S., Wood, K., Woosley, S., Wu, X., Xu, R., Yu, W., Yuan, F., Yuan, W., Yuan, Y., Zampa, G., Zampa, N., Zampieri, L., Zdunik, L., Zdziarski, A., Zech, A., Zhang, B., Zhang, C., Zingale, M., Zwart, F., University of Geneva [Switzerland], Eberhard Karls Universität Tübingen, Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Graduate School of the Natural Science and Technology, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), School of BioSciences [Melbourne], University of Melbourne-University of Melbourne-Royal Melbourne Institute of Technology University (RMIT University)-University of Queensland [Brisbane]-Australian National University (ANU)-The University of Western Australia (UWA), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université d'Orléans (UO)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Centre National d’Études Spatiales [Paris] (CNES), Université Libre de Bruxelles [Bruxelles] (ULB), Dublin City University, Dublin 9, Ireland, Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), China Information Technology Security Evaluation Center, Technical University of Denmark [Lyngby] (DTU), Université Grenoble Alpes (UGA), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Trieste, Institut national des sciences de l'Univers (INSU - CNRS)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Intégrative de la Cellule (I2BC), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Università degli Studi di Roma 'La Sapienza' [Rome], Radboud university [Nijmegen]-Radboud university [Nijmegen], Radboud university [Nijmegen], Universidad de Granada (UGR), Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Biologie Cellulaire (CRBM), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Catania [Catania], Laboratoire d'Ecologie Alpine (LECA), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Université Joseph Fourier - Grenoble 1 (UJF)-Université Grenoble Alpes (UGA), Centre National de la Recherche Scientifique (CNRS)-Université du Littoral Côte d'Opale, Stanford University [Stanford], Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU), Università degli studi di Napoli Federico II, IFP Energies nouvelles (IFPEN), National Institute for Nuclear Physics (INFN), Institut Jean Le Rond d'Alembert (DALEMBERT), Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse 1 Capitole (UT1)-Université Toulouse - Jean Jaurès (UT2J)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse 1 Capitole (UT1)-Université Toulouse - Jean Jaurès (UT2J), Ingénierie des Matériaux Polymères (IMP), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS), Centro Euro-Mediterraneo per i Cambiamenti Climatici (CMCC), Universität Heidelberg [Heidelberg], Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Réseau International des Instituts Pasteur (RIIP)-Institut National de la Recherche Scientifique [Québec] (INRS), Università di Bologna [Bologna] (UNIBO), University of California [Berkeley], University of California-University of California, Universita degli Studi di Padova, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Chalmers University of Technology [Göteborg], Astronomy, Jan-Willem A. den Herder, Shouleh Nikzad, Kazuhiro Nakazawa, Van Der Klis, M., Liu, L. -P., Zhang, S. -N., Atteia, J. -L., Ballantyne, D. R., Van Baren, C., Bellutti, P., Bonnet Bidaud, J. -M., Borghi, G., Briggs, M. S., Budtz-Jorgensen, C., Cadoux, F. R., Caliandro, G. A., Castro-Tirado, A. J., Cerda-Duran, P., Chateau, F., D'Ai, A., Dercksen, J. P. C., Den Herder, J. W., Di Salvo, T., Drake, S. A., Erkut, M. H., Ficorella, F., Finger, M. H., Fraser, G. W., Galloway, D. K., Galvez Sanchez, J. L., Garcia-Berro, E., Giles, A. B., Goluchova, K., Gotz, D., Hartmann, D. H., Haswell, C. A., Inam, S. C., In'Tzand, J. J. M., Jacobs, H. M., Jenke, P. A., Jose, J., Kalamkar, M., Kowalski, A. F., Kuiper, L. M., Lamb, F. K., Laubert, P. P., Maccarone, T. J., Markoff, S. B., Martinez, G., Mchardy, I. M., Medina-Tanco, G., Miller, M. C., Miller, J. M., Mulacova, J., Munoz-Darias, T., Norton, A. J., Olsen, P. E. H., Osborne, J. P., Paredes, J. M., Penacchioni, A. V., Perez, M. A., Perez-Torres, M., Peterson, B. M., Picciotto, A., Piemonte, C., Rachevski, A., Ray, P. S., De La Rie, R., Rischke, D. H., Rodriguez-Gil, P., Rossi, E. M. R., Russell, D. M., Sabau-Graziati, L., Schaffner-Bielich, J., Schnittman, J. D., Schwope, A. D., Seyler, J. -Y., Smith, D. M., Smith, P. J., Steiner, A. W., Stevens, A. L., Strohmayer, T. E., Thielemann, F. K., Torrejon, J. M., Torres, D. F., Vincent, F. H., Wilson-Hodge, C. A., Walk, S. J., Woosley, S. E., Xiao, L., Zorzi, N., Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Institut de Chimie du CNRS (INC)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Muséum national d'Histoire naturelle (MNHN), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Department of Psychiatry (Icahn School of Medicine at Mount Sinai) ( ISMMS ), Rutgers, The State University of New Jersey [New Brunswick] ( RUTGERS ), Institut fur Astronomie und Astrophysik, Astrophysique Interactions Multi-échelles ( AIM - UMR 7158 - UMR E 9005 ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Paris Diderot - Paris 7 ( UPD7 ), Kanazawa University ( KU ), Department of Earth Sciences, University of Oxford [Oxford], Centre Interdisciplinaire de Nanoscience de Marseille ( CINaM ), Aix Marseille Université ( AMU ) -Centre National de la Recherche Scientifique ( CNRS ), Tampere University of Technology [Tampere] ( TUT ), University of Southern Mississippi ( USM ), University of Southampton [Southampton], Istituto di Astrofisica Spaziale e Fisica Cosmica - Milano ( IASF-MI ), Istituto Nazionale di Astrofisica ( INAF ), Istituto di Astrofisica e Planetologia Spaziali ( IAPS ), Laboratoire d'Astrophysique de l'Observatoire Midi-Pyrénées ( LATT ), Université Paul Sabatier - Toulouse 3 ( UPS ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire Midi-Pyrénées ( OMP ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de recherche en astrophysique et planétologie ( IRAP ), Université Paul Sabatier - Toulouse 3 ( UPS ) -Observatoire Midi-Pyrénées ( OMP ) -Centre National de la Recherche Scientifique ( CNRS ), Swedish Institute of Space Physics [Uppsala] ( IRF ), Osservatorio Astronomico di Brera ( INAF ), Bibliothèque nationale de France ( BnF ), Istituto di Astrofisica Spaziale e Fisica cosmica - Palermo ( IASF-Pa ), ARC Centre of Excellence for Environmental Decisions ( ARC CEED ), The University of Western Australia ( UWA ) -Australian National University ( ANU ) -University of Queensland [Brisbane]-RMIT University [Melbourne]-University of Melbourne, ARC Centre of Excellence for Coral Reef Studies ( CoralCoE ), James Cook University ( JCU ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Anthropologie Moléculaire et Imagerie de Synthèse ( AMIS ), PRES Université de Toulouse-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de synthèse organique ( DCSO ), École polytechnique ( X ) -Centre National de la Recherche Scientifique ( CNRS ), Department of Pathology, University of Alabama at Birmingham, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, INAF-Osservatorio di Cagliari, Laboratoire d'Astrophysique de Bordeaux [Pessac] ( LAB ), Université de Bordeaux ( UB ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Bordeaux ( UB ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Théorique et Modèles Statistiques ( LPTMS ), Université Paris-Sud - Paris 11 ( UP11 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique et Chimie de l'Environnement et de l'Espace ( LPC2E ), Institut national des sciences de l'Univers ( INSU - CNRS ) -Université d'Orléans ( UO ) -Centre National de la Recherche Scientifique ( CNRS ), Université Libre de Bruxelles [Bruxelles] ( ULB ), Ocean and Earth Sciences, National Oceanography Centre Southampton, Dublin Institute for advanced studies, 31 Fitzwilliam Place, Dublin 2, Ireland, Mullard Space Science Laboratory ( MSSL ), University College of London [London] ( UCL ), Institut Parisien de Chimie Moléculaire ( IPCM ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Chinese Academy of Sciences [Beijing] ( CAS ), Laboratoire Univers et Théories ( LUTH ), Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Department of Applied Mathematics and Computer Science [Lyngby] ( DTU Compute ), Technical University of Denmark [Lyngby] ( DTU ), Institut für Astronomie und Astrophysik ( IAAT ), Anton Pannekoek Institute for Astronomy, University of Amsterdam, University of Cambridge [UK] ( CAM ), International Space Science Institute ( ISSI ), Université Grenoble Alpes - UFR Médecine ( UGA UFRM ), Université Grenoble Alpes ( UGA ), Institute of Perception, Action and Behaviour ( IPAB ), United States Geological Survey [Reston] ( USGS ), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux ( ARTEMIS ), Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de la Côte d'Azur, Université Côte d'Azur ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Max-Planck-Institut für Extraterrestrische Physik ( MPE ), Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology ( MIT ), Institut de Physique du Globe de Paris ( IPGP ), Institut national des sciences de l'Univers ( INSU - CNRS ) -IPG PARIS-Université Paris Diderot - Paris 7 ( UPD7 ) -Université de la Réunion ( UR ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Biologie Intégrative de la Cellule ( I2BC ), Université Paris-Sud - Paris 11 ( UP11 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Centre National de la Recherche Scientifique ( CNRS ), Matériaux, ingénierie et science [Villeurbanne] ( MATEIS ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique ( CNRS ) -Institut National des Sciences Appliquées de Lyon ( INSA Lyon ), Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ), University of Wisconsin-Madison [Madison], SRON Netherlands Institute for Space Research ( SRON ), University of Technology ( Opole ), Institute for Mathematics, Astrophysics and Particle Physics ( IMAPP ), Grp Fis Atmosfera, Ctr Andaluz Medio Ambiente CEAMA, Universidad de Granada ( UGR ), The Hong Kong Polytechnic University [Hong Kong] ( POLYU ), Chinese Academy of Sciences [Changchun Branch] ( CAS ), Department of Physics, Chemistry and Biology, Linköping University ( LIU ), Institut de Chimie des Substances Naturelles ( ICSN ), Centre National de la Recherche Scientifique ( CNRS ), Institut de Physique Nucléaire de Lyon ( IPNL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Astronomical Institute Anton Pannekoek ( AI PANNEKOEK ), University of Amsterdam [Amsterdam] ( UvA ), Erlangen Centre for Astroparticle Physics ( ECAP ), Friedrich-Alexander Universität Erlangen-Nürnberg ( FAU ), Centre de recherches de biochimie macromoléculaire ( CRBM ), Université Montpellier 1 ( UM1 ) -Université Montpellier 2 - Sciences et Techniques ( UM2 ) -Université de Montpellier ( UM ) -Centre National de la Recherche Scientifique ( CNRS ), Instituto Nacional de Pesquisas da Amazônia ( INPA ), Instituto Nacional de Pesquisas da Amazônia, Centre d'Ecologie et des Sciences de la COnservation ( CESCO ), Muséum National d'Histoire Naturelle ( MNHN ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire d'Ecologie Alpine ( LECA ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physico-Chimie de l'Atmosphère ( LPCA ), Université du Littoral Côte d'Opale-Centre National de la Recherche Scientifique ( CNRS ), Institut des Sciences Moléculaires de Marseille ( ISM2 ), Aix Marseille Université ( AMU ) -Ecole Centrale de Marseille ( ECM ) -Centre National de la Recherche Scientifique ( CNRS ), Space Telescope Science Institute ( STSci ), IFP Energies nouvelles ( IFPEN ), Laboratoire de Biométrie et Biologie Evolutive ( LBBE ), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique ( Inria ) -Centre National de la Recherche Scientifique ( CNRS ), University of Arkansas, Istituto Nazionale di Fisica Nucleare, Sezione di Trieste ( INFN, Sezione di Trieste ), National Institute for Nuclear Physics ( INFN ), Institut Jean Le Rond d'Alembert ( DALEMBERT ), Institut de Ciencies de l'Espai [Barcelona] ( ICE-CSIC ), Consejo Superior de Investigaciones Científicas [Spain] ( CSIC ), University of Reading ( UOR ), Universidade de Santiago de Compostela, Équipe Robotique et InteractionS ( LAAS-RIS ), Laboratoire d'analyse et d'architecture des systèmes [Toulouse] ( LAAS ), Institut National Polytechnique [Toulouse] ( INP ) -Institut National des Sciences Appliquées - Toulouse ( INSA Toulouse ), Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Université Paul Sabatier - Toulouse 3 ( UPS ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut National Polytechnique [Toulouse] ( INP ) -Institut National des Sciences Appliquées - Toulouse ( INSA Toulouse ), Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Université Paul Sabatier - Toulouse 3 ( UPS ) -Centre National de la Recherche Scientifique ( CNRS ), Ingénierie des Matériaux Polymères - Site INSA Lyon ( IMP ), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon ( INSA Lyon ), Université de Lyon-Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Université Jean Monnet [Saint-Étienne] ( UJM ) -Centre National de la Recherche Scientifique ( CNRS ), Leibniz-Institut für Astrophysik Potsdam ( AIP ), Daimler Chrysler AG ( Daimler ), Centre d'Etudes Nucléaires de Bordeaux Gradignan ( CENBG ), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Montserrat Volcano Observatory ( MVO ), Institut Armand Frappier ( INRS-IAF ), Institut National de la Recherche Scientifique [Québec] ( INRS ) -Réseau International des Instituts Pasteur ( RIIP ) -Institut Armand Frappier, Università di Bologna [Bologna] ( UNIBO ), Max-Planck-Institut für Radioastronomie, Argelander Institut für Astronomie, Bonn Universität [Bonn], Space Sciences Laboratory [Berkeley] ( SSL ), Christian-Albrechts-Universität zu Kiel ( CAU ), Universita degli Studi di Padova = University of Padua = Université de Padoue, APC - Gravitation ( APC-Gravitation ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Max-Planck-Institut-Max-Planck-Institut, California Institute of Technology ( CALTECH ), Mitsubishi Electric Research Laboratories ( MERL ), Mitsubishi Electric Research Laboratories, Institute for Astronomy, University of Amsterdam, The Netherland, University of Southern California ( USC ), National University of Defense Technology [Changsha], Department of Microtechnology and Nanoscience ( MC2 ), Université Chalmers, PSL Research University (PSL)-PSL Research University (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université d'Orléans (UO)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Université Nice Sophia Antipolis (UNS), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay, Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Den Herder, Jan-Willem A., Bautz, M., den Herder, Jan-Willem A., Takahashi, Tadayuki, Bautz, Marshall, Jan-Willem A. den Herder, Tadayuki Takahashi, Marshall Bautz, Liu, L. P., Zhang, S. N., Atteia, J. L., Bonnet Bidaud, J. M., Castro Tirado, A. J., D'Aı, A., den Herder, J. W., Gálvez Sanchez, J. L., In't Zand, J. J. M., Nucita, Achille, Seyler, J. Y., Wilson Hodge, C. A., Baldazzi, Giuseppe, Fuschino, Fabio, Bianchi, Stefano, Casella, Piergiorgio, DE ROSA, Alessandra, Giovannini, Gabriele, LA FRANCA, Fabio, Marinucci, Andrea, Paredes, M. J., Schneider, Raffaella, Vietri, Mario, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Université de La Réunion (UR)-Université Paris Diderot - Paris 7 (UPD7)-IPG PARIS-Institut national des sciences de l'Univers (INSU - CNRS), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), M., Feroci, E., Bozzo, S., Brandt, M., Hernanz, M., van der Kli, L. P., Liu, P., Orleanski, M., Pohl, A., Santangelo, S., Schanne, L., Stella, T., Takahashi, H., Tamura, A., Watt, J., Wilm, S., Zane, S. N., Zhang, S., Bhattacharyya, I., Agudo, M., Ahangarianabhari, C., Albertu, M., Alford, A., Alpar, D., Altamirano, L., Alvarez, L., Amati, C., Amoro, N., Andersson, A., Antonelli, A., Argan, R., Artigue, B., Artigue, J. L., Atteia, P., Azzarello, P., Bakala, D., Ballantyne, G., Baldazzi, M., Baldo, S., Balman, M., Barbera, C., van Baren, D., Barret, A., Baykal, M., Begelman, E., Behar, O., Behar, T., Belloni, F., Bernardini, G., Bertuccio, S., Bianchi, A., Bianchini, P., Binko, P., Blay, F., Bocchino, M., Bode, P., Bodin, I., Bombaci, J. M., Bonnet Bidaud, S., Boutlouko, F., Bouyjou, L., Bradley, J., Braga, M. S., Brigg, E., Brown, M., Buballa, N., Bucciantini, L., Burderi, M., Burgay, M., Bursa, C., Budtz Jørgensen, E., Cackett, F., Cadoux, P., Cai, G. A., Caliandro, R., Campana, S., Campana, X., Cao, F., Capitanio, J., Casare, P., Casella, A. J., Castro Tirado, E., Cavazzuti, Y., Cavechi, S., Celestin, P., Cerda Duran, D., Chakrabarty, N., Chamel, F., Château, C., Chen, Y., Chen, J., Chenevez, M., Chernyakova, J., Coker, R., Cole, A., Collura, M., Coriat, R., Cornelisse, L., Costamante, A., Cro, W., Cui, A., Cumming, G., Cusumano, B., Czerny, A., D'Aì, F., D'Ammando, V., D'Elia, Z., Dai, E., Del Monte, A., De Luca, D., De Martino, J. P. C., Dercksen, M., De Pasquale, A., De Rosa, M., Del Santo, S., Di Cosimo, N., Degenaar, J. W., den Herder, S., Diebold, T., Di Salvo, Y., Dong, I., Donnarumma, V., Doroshenko, G., Doyle, S. A., Drake, M., Durant, D., Emmanoulopoulo, T., Enoto, M. H., Erkut, P., Esposito, Y., Evangelista, A., Fabian, M., Falanga, Y., Favre, C., Feldman, R., Fender, H., Feng, V., Ferrari, C., Ferrigno, M., Finger, M. H., Finger, G. W., Fraser, M., Frerick, M., Fullekrug, F., Fuschino, M., Gabler, D. K., Galloway, J. L., Gálvez Sanchez, P., Gandhi, Z., Gao, E., Garcia Berro, B., Gendre, O., Gevin, S., Gezari, A. B., Gile, M., Gilfanov, P., Giommi, G., Giovannini, M., Giroletti, E., Gogu, A., Goldwurm, K., Goluchová, D., Götz, L., Gou, C., Gouiffe, P., Grandi, M., Grassi, J., Greiner, V., Grinberg, P., Groot, M., Gschwender, L., Gualtieri, M., Guedel, C., Guidorzi, L., Guy, D., Haa, P., Haensel, M., Hailey, K., Hamuguchi, F., Hansen, D. H., Hartmann, C. A., Haswell, K., Hebeler, A., Heger, M., Hempel, W., Hermsen, J., Homan, A., Hornstrup, R., Hudec, J., Huovelin, D., Huppenkothen, S. C., Inam, A., Ingram, J. J. M., In't Zand, G., Israel, K., Iwasawa, L., Izzo, H. M., Jacob, F., Jetter, T., Johannsen, P. A., Jenke, P., Jonker, J., Josè, P., Kaaret, K., Kalamkar, E., Kalemci, G., Kanbach, V., Kara, D., Karelin, D., Kataria, L., Keek, T., Kennedy, D., Klochkov, W., Kluzniak, E., Koerding, K., Kokkota, S., Komossa, S., Korpela, C., Kouveliotou, A. F., Kowalski, I., Kreykenbohm, L. M., Kuiper, D., Kunneriath, A., Kurkela, I., Kuvvetli, F., La Franca, C., Labanti, D., Lai, F. K., Lamb, C., Lachaud, P. P., Laubert, F., Lebrun, X., Li, E., Liang, O., Limousin, D., Lin, M., Linare, D., Linder, G., Lodato, F., Longo, F., Lu, N., Lund, T. J., Maccarone, D., Macera, S., Maestre, S., Mahmoodifar, D., Maier, P., Malcovati, J., Malzac, C., Malone, I., Mandel, V., Mangano, A., Manousaki, M., Marelli, J., Margueron, M., Marisaldi, S. B., Markoff, A., Markowitz, A., Marinucci, A., Martindale, G., Martínez, I. M., Mchardy, G., Medina Tanco, M., Mehdipour, A., Melato, M., Mendez, S., Mereghetti, S., Migliari, R., Mignani, M., Michalska, T., Mihara, M. C., Miller, J. M., Miller, T., Mineo, G., Miniutti, S., Morsink, C., Motch, S., Motta, M., Mouchet, G., Mouret, J., Mulačová, F., Muleri, T., Muñoz Daria, I., Negueruela, J., Neilsen, T., Neubert, A. J., Norton, M., Nowak, A., Nucita, P., O'Brien, M., Oertel, P. E. H., Olsen, M., Orienti, M., Orio, M., Orlandini, J. P., Osborne, R., Osten, F., Ozel, L., Pacciani, F., Paerel, S., Paltani, Paolillo, Maurizio, I., Papadaki, A., Papitto, Z., Paragi, J. M., Parede, A., Patruno, B., Paul, F., Pederiva, E., Perinati, A., Pellizzoni, A. V., Penacchioni, U., Peretz, M. A., Perez, M., Perez Torre, B. M., Peterson, V., Petracek, C., Pittori, J., Pon, J., Portell, A., Possenti, K., Postnov, J., Poutanen, M., Prakash, I., Prandoni, H., Le Provost, D., Psalti, J., Pye, J., Qu, D., Rambaud, P., Ramon, G., Ramsay, M., Rapisarda, A., Rashevski, I., Rashevskaya, P. S., Ray, N., Rea, S., Reddy, P., Reig, M., Reina Aranda, R., Remillard, C., Reynold, L., Rezzolla, M., Ribo, R., de la Rie, A., Riggio, A., Rio, D. H., Rischke, P., Rodríguez Gil, J., Rodriguez, R., Rohlf, P., Romano, E. M. R., Rossi, A., Rozanska, A., Rousseau, B., Rudak, D. M., Russell, F., Ryde, L., Sabau Graziati, T., Sakamoto, G., Sala, R., Salvaterra, D., Salvetti, A., Sanna, J., Sandberg, T., Savolainen, S., Scaringi, J., Schaffner Bielich, H., Schatz, J., Schee, C., Schmid, M., Serino, N., Shakura, S., Shore, J. D., Schnittman, R., Schneider, A., Schwenk, A. D., Schwope, A., Sedrakian, J. Y., Seyler, A., Shearer, A., Slowikowska, M., Sim, A., Smith, D. M., Smith, P. J., Smith, M., Sobolewska, V., Sochora, P., Soffitta, P., Soleri, L., Song, A., Spencer, A., Stamerra, B., Stapper, R., Staubert, A. W., Steiner, N., Stergioula, A. L., Steven, G., Stratta, T. E., Strohmayer, Z., Stuchlik, S., Suchy, V., Suleimanov, F., Tamburini, T., Tauri, F., Tavecchio, C., Tenzer, F. K., Thielemann, A., Tiengo, L., Tolo, F., Tombesi, J., Tomsick, G., Torok, J. M., Torrejon, D. F., Torre, E., Torresi, A., Tramacere, I., Traulsen, A., Troi, R., Turolla, S., Turriziani, S., Typel, P., Uter, P., Uttley, A., Vacchi, P., Varniere, S., Vaughan, S., Vercellone, M., Vietri, F. H., Vincent, V., Vrba, D., Walton, J., Wang, Z., Wang, S., Watanabe, R., Wawrzaszek, N., Webb, N., Weinberg, H., Wende, P., Wheatley, R., Wijer, R., Wijnand, M., Wille, C. A., Wilson Hodge, B., Winter, S. J., Walk, K., Wood, S. E., Woosley, X., Wu, R., Xu, W., Yu, F., Yuan, W., Yuan, Y., Yuan, G., Zampa, N., Zampa, L., Zampieri, L., Zdunik, A., Zdziarski, A., Zech, B., Zhang, C., Zhang, S., Zhang, M., Zingale, and F., Zwart
Subjects: X-ray timing, [ SDU.ASTR.GA ] Sciences of the Universe [physics]/Astrophysics [astro-ph]/Galactic Astrophysics [astro-ph.GA], Field of view, Astrophysics, 01 natural sciences, law.invention, law, Observatory, timing, 010303 astronomy & astrophysics, QB, Physics, microchannel plates. PROPORTIONAL COUNTER ARRAY, CALIBRATION, X-ray astronomy, Electronic, Optical and Magnetic Material, Applied Mathematics, Astrophysics::Instrumentation and Methods for Astrophysics, Computer Science Applications1707 Computer Vision and Pattern Recognition, X-ray detectors, Condensed Matter Physics, compact objects, X-ray spectroscopy, [SDU.ASTR.GA]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Galactic Astrophysics [astro-ph.GA], spectroscopy, Cosmic Vision, [ INFO ] Computer Science [cs], Silicon detector, Astrophysics::High Energy Astrophysical Phenomena, Condensed Matter Physic, Telescope, X-ray, Silicon detectors, Electronic, Optical and Magnetic Materials, Electrical and Electronic Engineering, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, Electronic, [INFO]Computer Science [cs], Optical and Magnetic Materials, Spectral resolution, DETECTOR, ta115, X-ray astronomy, Silicon detectors, timing, spectroscopy, 010308 nuclear & particles physics, X-ray imaging, Applied Mathematic, Neutron star, QB460-466 Astrophysics, Large Observatory For x-ray Timing (LOFT), Large Area Detector (LAD), Wide Field Monitor (WFM), Large Area Silicon Drift Detectors (SDD), Gamma-ray burst
Abstract: The Large Observatory For x-ray Timing (LOFT) is a mission concept which was proposed to ESA as M3 and M4 candidate in the framework of the Cosmic Vision 2015-2025 program. Thanks to the unprecedented combination of effective area and spectral resolution of its main instrument and the uniquely large field of view of its wide field monitor, LOFT will be able to study the behaviour of matter in extreme conditions such as the strong gravitational field in the innermost regions close to black holes and neutron stars and the supra-nuclear densities in the interiors of neutron stars. The science payload is based on a Large Area Detector (LAD, >8m2 effective area, 2-30 keV, 240 eV spectral resolution, 1 degree collimated field of view) and a Wide Field Monitor (WFM, 2-50 keV, 4 steradian field of view, 1 arcmin source location accuracy, 300 eV spectral resolution). The WFM is equipped with an on-board system for bright events (e.g., GRB) localization. The trigger time and position of these events are broadcast to the ground within 30 s from discovery. In this paper we present the current technical and programmatic status of the mission. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Published: 2016

28. Regulation of Meristem Morphogenesis by Cell Wall Synthases in Arabidopsis

Author: Monika S. Doblin, Christoph Schuster, Varodom Charoensawan, Cherie T. Beahan, Antony Bacic, Weibing Yang, Raymond Wightman, Elliot M. Meyerowitz, Alexis Peaucelle, Sainsbury Laboratory, University of Cambridge, ARC Centre of Excellence in Plant Cell Walls, University of Adelaide-University of Queensland [Brisbane]-School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne-Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, Department of Biochemistry, Faculty of Science, Mahidol University [Bangkok]-Ramathibodi Hospital, Integrative Computational BioScience Center, Mahidol University [Bangkok], Institut Jean-Pierre Bourgin (IJPB), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Howard Hughes Medical Institute and Division of Biology and Biological Engineering, California Institute of Technology (CALTECH), Sainsbury Laboratory Cambridge University (SLCU), University of Cambridge [UK] (CAM), University of Queensland [Brisbane]-School of BioSciences [Melbourne], University of Melbourne-University of Melbourne-University of Adelaide, European Project: 267196,EC:FP7:PEOPLE,FP7-PEOPLE-2010-COFUND,AGREENSKILLS(2012), Yang, Weibing [0000-0002-2379-5729], Schuster, Christoph [0000-0002-1948-2367], Wightman, Raymond [0000-0003-1295-4875], and Apollo - University of Cambridge Repository
Subjects: 0301 basic medicine, XYLAN, [SDV]Life Sciences [q-bio], education, Meristem, Morphogenesis, Arabidopsis, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell wall, 03 medical and health sciences, PECTIN, Cell Wall, Gene Expression Regulation, Plant, BIOSYNTHETIC HOMOGALACTURONAN GALACTURONOSYLTRANSFERASE, Gene expression, Botany, MUTANTS REVEALS, Primordium, RNA, Messenger, health care economics and organizations, GENE-EXPRESSION, Regulation of gene expression, Agricultural and Biological Sciences(all), THALIANA, Biochemistry, Genetics and Molecular Biology(all), Arabidopsis Proteins, Sequence Analysis, RNA, Glycosyltransferases, food and beverages, Meristem maintenance, biology.organism_classification, Cell biology, 030104 developmental biology, CELLULOSE, GROWTH, ARABINOGALACTAN, SHOOT APICAL MERISTEM, General Agricultural and Biological Sciences
Abstract: The cell walls of the shoot apical meristem (SAM), containing the stem cell niche that gives rise to the above-ground tissues, are crucially involved in regulating differentiation. It is currently unknown how these walls are built and refined or their role, if any, in influencing meristem developmental dynamics. We have combined polysaccharide linkage analysis, immuno-labelling and transcriptome profiling of the SAM to provide a spatio-temporal plan of the walls of this dynamic structure. We find that meristematic cells express only a core subset of 152 genes encoding cell wall glycosyltransferases (GTs). Systemic localization of all these GT mRNAs by in situ hybridization reveals members with either enrichment in or specificity to apical subdomains such as emerging flower primordia, and a large class with high expression in dividing cells. The highly localized and coordinated expression of GTs in the SAM suggests distinct wall properties of meristematic cells, and specific differences between newly forming walls and their mature descendants. Functional analysis demonstrates that a subset of CSLD genes is essential for proper meristem maintenance, confirming the key role of walls in developmental pathways.
Published: 2016

29. Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts

Author: Gordon Langsley, Geoffrey I. McFadden, Ming Kalanon, David Morse, Wesley A. J. Webster, Bos, Mireille, School of BioSciences [Melbourne], Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Funded by National Health and MedicalResearch Council (Australia), Australian ResearchCouncil, Labex ParaFrap - ANR-11-LABX-0024., School of BioSciences, University of Melbourne, Institut Cochin (UM3 (UMR 8104 / U1016)), and Université Paris Descartes - Paris 5 (UPD5) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Centre National de la Recherche Scientifique (CNRS)
Subjects: Proteomics, 0301 basic medicine, Plasmodium, Cell Membranes, Protozoan Proteins, lcsh:Medicine, Endoplasmic Reticulum, Biochemistry, 0302 clinical medicine, Cloning, Molecular, lcsh:Science, Protozoans, Secretory Pathway, Multidisciplinary, biology, Malarial Parasites, Transport protein, Cell biology, Protein Transport, Cell Processes, Cellular Structures and Organelles, Research Article, Recombinant Fusion Proteins, Plasmodium falciparum, Schizonts, Research and Analysis Methods, Apicomplexa, 03 medical and health sciences, Parasite Groups, DNA-binding proteins, parasitic diseases, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Integral Membrane Proteins, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Vesicles, Molecular Biology Techniques, Molecular Biology, Plasmodium (life cycle), Rhoptry, Endoplasmic reticulum, lcsh:R, fungi, Organisms, Biology and Life Sciences, Membrane Proteins, Proteins, Cell Biology, biology.organism_classification, Fusion protein, Molecular biology, Parasitic Protozoans, rab1 GTP-Binding Proteins, 030104 developmental biology, Membrane protein, Parasitology, lcsh:Q, 030217 neurology & neurosurgery, Cloning
Abstract: International audience; Over-expression of a GFP-PfRab1A fusion protein in Plasmodium falciparum schizonts produces a punctate pattern of fluorescence typical of rhoptries, secretory organelles involved in host cell invasion. The GFP-positive bodies were purified by a combination of differential and density gradient centrifugation and their protein content determined by MS/MS sequencing. Consistent with the GFP rhoptry-like pattern of transgenic parasites, four of the 19 proteins identified have been previously described to be rhoptry-associated and another four are ER or ER-associated proteins. Confirmation that GFP-PfRab1A decorates rhoptries was obtained by its co-localization with Rap1 and Ron4 in late phase schizonts. We conclude that PfRab1A potentially regulates vesicular traffic from the endoplasmic reticulum to the rhoptries in Apicomplexa parasites.
Published: 2016

30. The elusive paradox: owner--intruder roles, strategies, and outcomes in parasitoid contests

Author: Marlène Goubault, Tom Bentley, Tristan T. Hull, Ian C.W. Hardy, School of BioSciences, University of Nottingham, UK (UON), School of Biosciences, Institut de recherche sur la biologie de l'insecte UMR7261 (IRBI), and Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)
Subjects: 0106 biological sciences, Value (ethics), Biology, CONTEST, 010603 evolutionary biology, 01 natural sciences, Outcome (game theory), Parasitoid wasp, Parasitoid, Microeconomics, Empirical research, Resource (project management), 0501 psychology and cognitive sciences, 050102 behavioral science & comparative psychology, Ecology, Evolution, Behavior and Systematics, partial respect, Developmental stage, antibourgeois strategy, Ecology, 05 social sciences, biology.organism_classification, resource value asymmetry, Goniozus legneri, paradoxical strategy, Animal Science and Zoology, maternal investment, [SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis
Abstract: Models of dyadic contests for indivisible resources have predicted that the owner–intruder role distinction can suffice as a cue for evolutionarily stable resolution. This outcome may be ‘‘common sense’’ (prior owners retain the resource) or counterintuitively ‘‘paradoxical’’ (the intruder takes over), but the most recent models predict paradoxes to be an infrequent result, and there are also very few candidate examples provided by empirical study. Possible paradoxical outcomes were recently reported from the parasitoid wasp Goniozus legneri in which adult females compete directly for hosts. Here we provide further investigation, taking into account influences of contest ability (body size) and the value of the host to each contestant (correlated with the developmental stage of the owner’s brood). We additionally evaluate contest strategies in terms of respect for ownership as evidenced by attack behavior during contests. Goniozus legneri shows weak, and thus only partial, respect for role asymmetries: such mixed strategies are predicted by recent models that assume population-level feedback on resource value parameters. Contest outcomes are influenced by asymmetries in resource value and body size and are generally common sense. Instances of paradoxical contests remain predictably elusive. Key words: antibourgeois strategy, Goniozus legneri, maternal investment, paradoxical strategy, partial respect, resource value asymmetry. [Behav Ecol]
Published: 2009

31. The green seaweed Ulva: a model system to study morphogenesis

Author: FrÃ©dÃ©ric Mineur, Olivier De Clerck, John H. F. Bothwell, Thomas Wichard, Juliet C. Coates, BÃ©nÃ©dicte Charrier, Institute for Inorganic and Analytical Chemistry, Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M), Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), School of Biological Sciences, Queen's University [Belfast] (QUB), School of Biological and Biomedical Sciences and Durham Energy Institute, Phycology Research Group and Center for Molecular Phylogenetics and Evolution, Universiteit Gent = Ghent University [Belgium] (UGENT), School of Biosciences, University of Alabama at Birmingham [ Birmingham] (UAB)-School of Biosciences, Durham University, and Universiteit Gent = Ghent University (UGENT)
Subjects: 0106 biological sciences, ENTEROMORPHA, ALGA ULVA, Plant Science, algal genetics, chlorophyta, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, lcsh:Plant culture, 01 natural sciences, Mini Review Article, AXENIC CULTURE, 03 medical and health sciences, Algae, LACTUCA CHLOROPHYTA, Botany, green tides, lcsh:SB1-1110, Ecosystem, GAMETE RELEASE, 14. Life underwater, GENETIC-CONTROL, model organism, 030304 developmental biology, holobiont, 0303 health sciences, biology, Primary producers, Ecology, 010604 marine biology & hydrobiology, Ulvophyceae, GENOME REVEALS, Biology and Life Sciences, multicellular organism, biology.organism_classification, EPIPHYTIC BACTERIAL COMMUNITY, Holobiont, Benthic zone, MUTABILIS, ARABIDOPSIS-THALIANA, Epiphyte, Sea lettuce
Abstract: International audience; Green macroalgae, mostly represented by the Ulvophyceae, the main multicellular branch of the Chlorophyceae, constitute important primary producers of marine and brackish coastal ecosystems. Ulva or sea lettuce species are some of the most abundant representatives, being ubiquitous in coastal benthic communities around the world. Nonetheless the genus also remains largely understudied. This review highlights Ulva as an exciting novel model organism for studies of algal growth, development and morphogenesis as well as mutualistic interactions. The key reasons that Ulva is potentially such a good model system are: (i) patterns of Ulva development can drive ecologically important events, such as the increasing number of green tides observed worldwide as a result of eutrophication of coastal waters, (ii) Ulva growth is symbiotic, with proper development requiring close association with bacterial epiphytes, (iii) Ulva is extremely developmentally plastic, which can shed light on the transition from simple to complex multicellularity and (iv) Ulva will provide additional information about the evolution of the green lineage.
Published: 2015

32. Understanding 'green' multicellularity: do seaweeds hold the key?

Author: Umm-E-Aiman, Juliet C. Coates, Bénédicte Charrier, School of Biosciences, University of Alabama at Birmingham [ Birmingham] (UAB)-School of Biosciences, Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M), Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Station biologique de Roscoff [Roscoff] (SBR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Station biologique de Roscoff [Roscoff] (SBR), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
Subjects: 0106 biological sciences, macroalgae, Cell, toolkit, genetic toolkit, Plant Science, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, lcsh:Plant culture, 010603 evolutionary biology, 01 natural sciences, 03 medical and health sciences, Algae, medicine, lcsh:SB1-1110, Organism, 030304 developmental biology, 0303 health sciences, biology, Ecology, plants, Opinion Article, multicellularity, biology.organism_classification, Multicellular organism, medicine.anatomical_structure, Evolutionary biology, transitions, life-cycles
Abstract: International audience; Living organisms are unicellular, composed of a single cell, or multicellular, where a group of up to ~1012 cells functions co-operatively (Kaiser, 2001). All multicellular organisms evolved from single-celled ancestors; every individual organism arises from a unicell and reproduces by forming unicells. Multicellularity enables competitive advantages, and may have shaped our oxygen-rich atmosphere (Grosberg and Strathmann, 1998; Kaiser, 2001; Schirrmeister et al., 2013). Multicellularity has evolved multiple times: animals, plants, algae, amoebae, fungi, and bacteria are or can all be multicellular (King, 2004; Grosberg and Strathmann, 2007; Rokas, 2008; Claessen et al., 2014). Multicellularity can be clonal (arising from division of a single cell) or aggregative (aggregation of genetically diverse cells), with clonal multicellularity considered evolutionarily more stable (Grosberg and Strathmann, 1998). The molecular mechanisms by which organisms become multicellular are not well understood. In this article, we outline eukaryotic multicellular evolution, and discuss how to increase our future understanding.
Published: 2015

33. Phenotyping pipeline reveals major seedling root growth QTL in hexaploid wheat

Author: Oorbessy Gaju, Darren M. Wells, Jonathan A. Atkinson, Simon Griffiths, Jacques Le Gouis, M. John Foulkes, Michael P. Pound, Marcus Griffiths, Julie King, Malcolm J. Bennett, Luzie U. Wingen, School of Biosciences, Centre for Plant Integrative Biology, University of Nottingham, UK (UON), Norwich Research Park, Department of Crop Genetics, John Innes Centre [Norwich], School of Biosciences, Division of Plant and Crop Sciences, Génétique Diversité et Ecophysiologie des Céréales (GDEC), Institut National de la Recherche Agronomique (INRA)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), Biotechnology and Biological Sciences Research Council, Engineering and Physical Sciences Research Council Centre for Integrative Systems Biology, European Research Council, BBSRC, Belgian Science Policy Office IAP7/29, Royal Society, Institut National de la Recherche Agronomique, and Biotechnology and Biological Sciences Research Council (BBSRC)-Biotechnology and Biological Sciences Research Council (BBSRC)
Subjects: 0106 biological sciences, Root growth, Nitrogen, Physiology, root system architecture, Quantitative Trait Loci, Winter wheat, Plant Science, Biology, Quantitative trait locus, Plant Roots, 01 natural sciences, Chromosomes, Plant, Polyploidy, 03 medical and health sciences, Quantitative Trait, Heritable, high-throughput phenotyping, root system architecture, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Cultivar, Triticum, 030304 developmental biology, 0303 health sciences, Chromosome, food and beverages, biology.organism_classification, Phenotype, Agronomy, Seedlings, Germination, Seedling, Doubled haploidy, High-throughput phenotyping, Research Paper, 010606 plant biology & botany
Abstract: Highlight A phenotyping pipeline was used to quantify seedling root architectural traits in a wheat double haploid mapping population. QTL analyses revealed a potential major effect gene regulating seedling root vigour/growth., Seedling root traits of wheat (Triticum aestivum L.) have been shown to be important for efficient establishment and linked to mature plant traits such as height and yield. A root phenotyping pipeline, consisting of a germination paper-based screen combined with image segmentation and analysis software, was developed and used to characterize seedling traits in 94 doubled haploid progeny derived from a cross between the winter wheat cultivars Rialto and Savannah. Field experiments were conducted to measure mature plant height, grain yield, and nitrogen (N) uptake in three sites over 2 years. In total, 29 quantitative trait loci (QTLs) for seedling root traits were identified. Two QTLs for grain yield and N uptake co-localize with root QTLs on chromosomes 2B and 7D, respectively. Of the 29 root QTLs identified, 11 were found to co-localize on 6D, with four of these achieving highly significant logarithm of odds scores (>20). These results suggest the presence of a major-effect gene regulating seedling root vigour/growth on chromosome 6D.
Published: 2015

34. Functional response: rigorous estimation and sensitivity to genetic variation in prey

Author: Phillip Cassey, Thomas Tully, Régis Ferrière, Fonctionnement et évolution des systèmes écologiques (FESE), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), School of Biosciences, University of Alabama at Birmingham [ Birmingham] (UAB)-School of Biosciences, Dept of Ecology and Evolutionary Biology, University of Arizona-Dept of Ecology and Evolutionary Biology, École normale supérieure - Paris (ENS-PSL), Department of Ecology and Evolutionary Biology [University of Arizona], and University of Arizona
Subjects: 0106 biological sciences, Estimation theory, Ecology, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Functional response, Function (mathematics), Biology, 010603 evolutionary biology, 01 natural sciences, Predation, 010602 entomology, Genetic variation, Sensitivity (control systems), Genetic variability, Constant (mathematics), Biological system, Ecology, Evolution, Behavior and Systematics
Abstract: Holling's type II functional response is a cornerstone of community ecology and coevolutionary theory. The so-called disc equation is the most widely used model of the type II response, yet thus far no robust experimental assessment has been achieved in any single system. Fundamental issues that remain to be assessed include whether the assumptions of the disc equation are fulfilled, whether the disc equation yields accurate estimates of predation-related individual traits, and whether differences in disc equation parameters can capture genetic variation in prey behaviour. This paper provides a rigorous approach to all of these questions. The functional response of the predatory mite Pergamasus crassipes on three genetically distinct clones of the springtail Folsomia candida was measured at six levels of prey density in controlled conditions where prey number and arena size were concomitantly manipulated. A crucial assumption of Holling's disc equation was fulfilled by maintaining a constant prey density for the entire experimental period of predation. The timing of each attack and capture, as well as the duration of the handling time, were recorded by constant observation. We contrasted three different methods to calculate functional response curves: (1) indirect estimation of the disc equation's parameters from the number of prey killed by the end of each experimental run; (2) direct estimation of the parameters via a unique protocol of constant observation; and (3) independently deriving a function based on direct measurements of encounter rate and attack success. The basic assumptions of the disk equation were globally fulfilled. Estimations of the functional response's parameters (type II) were remarkably congruent across approach (1) and (2). A single genetic effect was detected - the relationship between the encounter rate and prey density differed significantly between clones - whereas a direct comparison of functional response across clones failed to reveal genetic variation.
Published: 2005

35. Inflammatory Responses Induced by the Monophasic Variant of Salmonella Typhimurium in Pigs Play a Role in the High Shedder Phenotype and Fecal Microbiota Composition

Author: Kempf, Florent, Cordoni, Guido, Chaussé, Anne-Marie, Drumo, Rosanna, Brown, Helen, Horton, Daniel L., Paboeuf, Frédéric, Denis, Martine, Velge, Philippe, La Ragione, Roberto, Kerouanton, Annaëlle, Infectiologie et Santé Publique (UMR ISP), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Surrey (UNIS), Laboratoire de Ploufragan-Plouzané-Niort [ANSES], Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), School of Biosciences and Medicine [Surrey, UK], and European Project: 773830,H2020-SFS-2017-1 ,MoMIR-PPC (a component of European Joint Programme One Health) (2018)
Subjects: pig, [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, gut microbiota, Physiology, high shedder, immunity, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Biochemistry, Microbiology, Computer Science Applications, Salmonella, inflammation, Modeling and Simulation, Genetics, Molecular Biology, Ecology, Evolution, Behavior and Systematics
Abstract: International audience; Pigs infected with Salmonella may excrete large amounts of Salmonella, increasing the risk of spread of this pathogen in the food chain. Identifying Salmonella high shedder pigs is therefore required to mitigate this risk. We analyzed immune-associated markers and composition of the gut microbiota in specific-pathogen-free pigs presenting different shedding levels after an oral infection with Salmonella. Immune response was studied through total blood cell counts, production of anti-Salmonella antibodies and cytokines, and gene expression quantification. Total Salmonella shedding for each pig was estimated and hierarchical clustering was used to cluster pigs into high, intermediate, and low shedders. Gut microbiota compositions were assessed using 16S rRNA microbial community profiling. Comparisons were made between control and inoculated pigs, then between high and low shedders pigs. Prior to infection, high shedders had similar immunological profiles compared to low shedders. As soon as 1 day postinoculation (dpi), significant differences on the cytokine production level and on the expression level of several host genes related to a proinflammatory response were observed between high and low shedders. Infection with Salmonella induced an early and profound remodeling of the immune response in all pigs, but the intensity of the response was stronger in high shedders. In contrast, low shedders seroconverted earlier than high shedders. Just after induction of the proinflammatory response (at 2 dpi), some taxa of the fecal microbiota were specific to the shedding phenotypes. This was related to the enrichment of several functional pathways related to anaerobic respiration in high shedders. In conclusion, our data show that the immune response to Salmonella modifies the fecal microbiota and subsequently could be responsible for shedding phenotypes. Influencing the gut microbiota and reducing intestinal inflammation could be a strategy for preventing Salmonella high shedding in livestock. IMPORTANCE Salmonellosis remains the most frequent human foodborne zoonosis after campylobacteriosis and pork meat is considered one of the major sources of human foodborne infections. At the farm, host heterogeneity in pig infection is problematic. High Salmonella shedders contribute more significantly to the spread of this foodborne pathogen in the food chain. The identification of predictive biomarkers for high shedders could help to control Salmonella in pigs. The purpose of the present study was to investigate why some pigs become super shedders and others low shedders. We thus investigated the differences in the fecal microbial composition and the immune response in orally infected pigs presenting different Salmonella shedding patterns. Our data show that the proinflammatory response induced by S. Typhimurium at 1 dpi could be responsible for the modification of the fecal microbiota composition and functions observed mainly at 2 and 3 dpi and to the low and super shedder phenotypes.
Published: 2023

36. Hydroclimatic vulnerability of peat carbon in the central Congo Basin

Author: Yannick Garcin, Enno Schefuß, Greta C. Dargie, Donna Hawthorne, Ian T. Lawson, David Sebag, George E. Biddulph, Bart Crezee, Yannick E. Bocko, Suspense A. Ifo, Y. Emmanuel Mampouya Wenina, Mackline Mbemba, Corneille E. N. Ewango, Ovide Emba, Pierre Bola, Joseph Kanyama Tabu, Genevieve Tyrrell, Dylan M. Young, Ghislain Gassier, Nicholas T. Girkin, Christopher H. Vane, Thierry Adatte, Andy J. Baird, Arnoud Boom, Pauline Gulliver, Paul J. Morris, Susan E. Page, Sofie Sjögersten, Simon L. Lewis, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institute of Geosciences [Potsdam], University of Potsdam = Universität Potsdam, Center for Marine Environmental Sciences [Bremen] (MARUM), Universität Bremen, School of Geography [Leeds], University of Leeds, School of Geography and Geosciences [St Andrews], University of St Andrews [Scotland], IFP Energies nouvelles (IFPEN), Institute of Earth Surface Dynamics, Université de Lausanne = University of Lausanne (UNIL), University Marien Ngouabi of Brazzaville (umng), Université de Kisangani, Université de Mbandaka, Department of Geography [Leicester], University of Leicester, Cranfield University, British Geological Survey (BGS), Institute of Earth Sciences [Lausanne], Scottish Universities Environmental Research Centre (SUERC), University of Glasgow-University of Edinburgh, University of Nottingham, School of Biosciences, University of Nottingham, UK (UON), University College of London [London] (UCL), ANR-19-CE01-0022,ORACLE,Dynamique hydroclimatique et cycle du carbone dans le bassin central du Congo au cours de l'Holocène(2019), NERC, University of St Andrews. School of Geography & Sustainable Development, University of St Andrews. Environmental Change Research Group, and University of St Andrews. Bell-Edwards Geographic Data Institute
Subjects: Soil, Multidisciplinary, GE, Congo, MCP, SDG 13 - Climate Action, [SDU.STU]Sciences of the Universe [physics]/Earth Sciences, DAS, Carbon cycle, Palaeoclimate, Tropical ecology, Carbon, GE Environmental Sciences
Abstract: Funding: This work was funded by CongoPeat—a NERC large grant (NE/R016860/1) to S.L.L., I.T.L., S.E.P., A.B., A.J.B., P.J.M., P.G. and S.S. Natural Environment Research Council (CASE award to S.L.L. and G.C.D.), Leeds–York NERC Doctoral Training Partnership (‘SPHERES’) award to B.C. (NE/L002574/1), NERC Radiocarbon Facility NRCF010001 (alloc. no. 1688.0313, 1797.0414, 2222.1119, 14.108 and 2329.0920 to I.T.L., S.L.L., G.E.B., B.C., P.G. and G.C.D.), Wildlife Conservation Society – Congo (to G.C.D.), the Royal Society (to S.L.L.), Philip Leverhulme Prize (to S.L.L.), and a Greenpeace Fund award (to S.L.L.). E.S. was supported by the DFG–Cluster of Excellence ‘The Ocean in the Earth System’ at MARUM. C.H.V. publishes with permission of the Executive Director of the British Geological Survey, UKRI. The forested swamps of the central Congo Basin store approx. 30 billion metric tonnes of carbon in peat1,2. Little is known about the vulnerability of these carbon stocks. Here we investigate this vulnerability using peat cores from a large interfluvial basin in the Republic of the Congo and palaeoenvironmental methods. We find that peat accumulation began at least at 17,500 calibrated years before present (cal. yr BP; taken as AD 1950). Our data show that the peat that accumulated between around 7,500 to around 2,000 cal. yr BP is much more decomposed compared with older and younger peat. Hydrogen isotopes of plant waxes indicate a drying trend, starting at approx. 5,000 cal. yr BP and culminating at approx. 2,000 cal. yr BP, coeval with a decline in dominant swamp forest taxa. The data imply that the drying climate probably resulted in a regional drop in the water table, which triggered peat decomposition, including the loss of peat carbon accumulated prior to the onset of the drier conditions. After approx. 2,000 cal. yr BP, our data show that the drying trend ceased, hydrol. conditions stabilized and peat accumulation resumed. This reversible accumulation-loss-accumulation pattern is consistent with other peat cores across the region, indicating that the carbon stocks of the central Congo peatlands may lie close to a climatically driven drought threshold. Further research should quantify the combination of peatland threshold behavior and droughts driven by anthropogenic carbon emissions that may trigger this pos. carbon cycle feedback in the Earth system. Publisher PDF
Published: 2022

37. Enthalpy/entropy compensation effects from cavity desolvation underpin broad ligand binding selectivity for rat odorant binding protein 3

Author: Katherine L. Portman, Stephen B. Carr, Jed Long, Loïc Briand, David J. Scott, Donald J. Winzor, Mark S. Searle, National Centre for Macromolecular Hydrodynamics, School of Biosciences - School of Chemistry, Centre for Biomolecular Sciences, University of Nottingham, UK (UON), School of Chemistry, Centre for Biomolecular Sciences, ISIS Neutron and Muon Source (ISIS), STFC Rutherford Appleton Laboratory (RAL), Science and Technology Facilities Council (STFC)-Science and Technology Facilities Council (STFC), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Centre National de la Recherche Scientifique (CNRS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), School of Chemistry and Molecular Biosciences, University of Southern Queensland (USQ), Neutron and Muon Source and Research Complex at Harwell, National Centre for Macromolecular Hydrodynamics, School of Biosciences, Biotechnology and Biological Sciences Research Council (UK) [BB/D522870/1], BBSRC DTA, Medical Research Council (UK), BBSKC (UK), Science and Technology Facilities Council, University of Nottingham, University of Nottingham, UK ( UON ), ISIS Neutron and Muon Source and Research Complex at Harwell, Rutherford Appleton Laboratory, Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), University of Queensland ( UQ ), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), and University of Queensland (UQ)
Subjects: Models, Molecular, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Odorant binding, olfactory receptor, [ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition, Enthalpy, water, Drug design, Crystallography, X-Ray, Ligands, Receptors, Odorant, entropy compensation, Biochemistry, Hydrophobic effect, Lactones, different chemical classes, site, Animals, Molecule, Nuclear Magnetic Resonance, Biomolecular, isotopically enriched proteins, biology, Chemistry, carbonic-anhydrase, [ SDV.BIO ] Life Sciences [q-bio]/Biotechnology, Ligand (biochemistry), Rats, Crystallography, Enthalpy–entropy compensation, Solvents, Odorant-binding protein, biology.protein, Biophysics, Thermodynamics, identification, recognition, solvent reorganization, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Protein Binding
Abstract: Evolution has produced proteins with exquisite ligand binding specificity, and manipulating this effect has been the basis for much of modern rational drug design. However, there are general classes of proteins with broader ligand selectivity linked to function, the origin of which is poorly understood. The odorant binding proteins (OBPs) sequester volatile molecules for transportation to the olfactory receptors. Rat OBP3, which we characterize by X-ray crystallography and NMR, binds a homologous series of aliphatic gamma-lactones within its aromatic-rich hydrophobic pocket with remarkably little variation in affinity but extensive enthalpy/entropy compensation effects. We show that the binding energetics are modulated by two desolvation processes with quite different thermodynamic signatures. Ligand desolvation follows the classical hydrophobic effect; however, cavity desolvation is consistent with the liberation of "high energy" water molecules back into bulk solvent with a strong, but compensated, enthalpic contribution, which together. underpin the origins of broad ligand binding selectivity.
Published: 2014

38. A molecular analysis of predation by generalist predators on the codling moth and the oriental fruit moth in organic apple orchards

Author: Boreau De Roincé, Catherine, Lavigne, Claire, Ricard, Jean-Michel, Franck, Pierre, Bouvier, Jean-Charles, Garcin, Alain, Symondson, W. O. C., Centre Technique Interprofessionnel des Fruits et Légumes (CTIFL), Unité de recherche Plantes et Systèmes de Culture Horticoles (PSH), Institut National de la Recherche Agronomique (INRA), School of Biosciences [Cardiff], Cardiff University, ProdInra, Archive Ouverte, and Cardiff School of Biosciences
Subjects: [SDE.BE] Environmental Sciences/Biodiversity and Ecology, diagnostic PCR, apple orchard, generalist predator, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, tortricidae
Abstract: Conference; Biological control by conservation of native natural enemies can help to reduce the need for pesticides and prevent their detrimental effects upon the environment. Here we assess the role of ground-active generalist predators as natural enemies of two tortricid pests in apple orchards. Using diagnostic PCR on the gut of field-caught ground-active predators, we found no difference in predation rates on these two pests. Spiders were the most efficient predators of moths in spring while the carabid beetles, feeding on diapausing larvae, were important in autumn. The temporal complementarity between spiders and carabid beetles highlights the need for diverse predator assemblages to optimise conservation biological control.
Published: 2012

39. Analyzing lateral root development: how to move forward

Author: A. Glyn Bengough, Ulrich Schurr, Renze Heidstra, Sacha J. Mooney, Hidehiro Fukaki, Philip N. Benfey, Benjamin Péret, Jonathan P. Lynch, John P. Hammond, Lionel X. Dupuy, Ilda Casimiro, Marta Joan Laskowski, Marc Lepetit, Tom Beeckman, Ive De Smet, Phillipe Nacry, Laurent Laplaze, Xavier Draye, Hanma Zhang, Philip J. White, Frank Hochholdinger, Malcolm J. Bennett, Martin R. Broadley, Boris Parizot, Division of Plant and Crop Sciences (DPCS), School of Biosciences-University of Nottingham, UK (UON), The James Hutton Institute, Laboratoire Commun de Microbiologie (LCM), Department of Plant Systems Biology, State University of Ghent, Universidad de Extremadura (UEX), Molecular Genetic, Utrecht University [Utrecht]-Faculty of Science-Department of Biology, Biology Department, Oberlin College, Laboratoire des symbioses tropicales et méditerranéennes (UMR LSTM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institute of Crop Science and Resource Conservation (INRES), Rheinische Friedrich-Wilhelms-Universität Bonn, Earth and Life Institute [Louvain-La-Neuve] (ELI), Université Catholique de Louvain (UCL), Centre for Plant Sciences [Leeds], University of Leeds-Faculty of Biological Sciences-Institute of Integrative and Comparative Biology, Signalisation de l'Adaptation des Végétaux à l'Environnement (SAVE), Institut de Biosciences et Biotechnologies d'Aix-Marseille (ex-IBEB) (BIAM), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Department of Biology, Kobe University, Centre for Plant Integrative Biology [Nothingham] (CPIB), University of Nottingham, UK (UON), Division of Agricultural and Environmental Sciences, Department of Horticulture, Pennsylvania State University (Penn State), Penn State System-Penn State System, Biochimie et Physiologie Moléculaire des Plantes (BPMP), Université de Montpellier (UM)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), Institute of Bio- and Geosciences-2: Plant Sciences, Forschungszentrum Jülich GmbH, Diversité, adaptation, développement des plantes (UMR DIADE), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), Department of Biology and Institute for Genome Science and Policy Center for Systems Biology, Duke University [Durham], Center for Plant Systems Biology (PSB Center), Vlaams Instituut voor Biotechnologie [Ghent, Belgique] (VIB), Universidad de Extremadura - University of Extremadura (UEX), Institute of Crop Science and Resource Conservation [Bonn] (INRES), Université Catholique de Louvain = Catholic University of Louvain (UCL), Plant Environmental Physiology and Stress Signaling (PEPSS), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association-Helmholtz-Gemeinschaft = Helmholtz Association, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), University of Nottingham, UK (UON)-School of Biosciences, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Division of Plant and Crop Sciences ( DPCS ), School of Biosciences-Loughborough-University of Nottingham, UK ( UON ), James Hutton Institute ( JHI ), Invergowrie, Laboratoire Commun de Microbiologie ( LCM ), Universidad de Extremadura, Facultad de Ciencias, Laboratoire des symbioses tropicales et méditerranéennes ( LSTM ), Centre de Coopération Internationale en Recherche Agronomique pour le Développement ( CIRAD ) -Université Montpellier 1 ( UM1 ) -Institut National de la Recherche Agronomique ( INRA ) -Université Montpellier 2 - Sciences et Techniques ( UM2 ) -Université de Montpellier ( UM ) -Institut national d’études supérieures agronomiques de Montpellier ( Montpellier SupAgro ), Institute of Crop Science and Resource Conservation ( INRES ), Bonn Universität [Bonn], Earth and Life Institute [Louvain-La-Neuve], Université Catholique de Louvain ( UCL ), Laboratoire de Biologie du Développement des Plantes ( LBDP ), Université de la Méditerranée - Aix-Marseille 2-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ), Centre for Plant Integrative Biology [Nothingham] ( CPIB ), University of Nottingham, UK ( UON ), School of Biosciences-University of Nottingham, UK ( UON ), PennState University [Pennsylvania] ( PSU ), Biochimie et Physiologie Moléculaire des Plantes ( BPMP ), Centre international d'études supérieures en sciences agronomiques ( Montpellier SupAgro ) -Institut national de la recherche agronomique [Montpellier] ( INRA Montpellier ) -Université de Montpellier ( UM ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut national d’études supérieures agronomiques de Montpellier ( Montpellier SupAgro ), Forschungszentrum Jülich, IBG-2: Plant Sciences, Diversité, adaptation, développement des plantes ( DIADE ), Centre de Coopération Internationale en Recherche Agronomique pour le Développement ( CIRAD ) -Université de Montpellier ( UM ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut de Recherche pour le Développement ( IRD [France-Sud] ), and Duke university [Durham]
Subjects: 0106 biological sciences, [ SDV.BV ] Life Sciences [q-bio]/Vegetal Biology, Root (linguistics), Process (engineering), growth, MESH : Plant Roots, Plant Developmental Biology, MESH: Plant Roots, plant, Plant Science, Agricultural engineering, system architecture, Biology, Plant Roots, 01 natural sciences, ray computed-tomography, 03 medical and health sciences, traits, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, nutrient-uptake, phosphorus, MESH: Models, Theoretical, 030304 developmental biology, 2. Zero hunger, Abiotic component, 0303 health sciences, Vegetal Biology, MESH : Models, Theoretical, Ecology, business.industry, Lateral root, green-revolution, Biology and Life Sciences, Cell Biology, Models, Theoretical, 15. Life on land, Variety (cybernetics), arabidopsis, Agriculture, Sustainability, Commentary, Systems architecture, business, auxin, Biologie végétale, 010606 plant biology & botany
Abstract: L'article original est publié par The American Society of Plant Biologists; International audience; Roots are important to plants for a wide variety of processes, including nutrient and water uptake, anchoring and mechanical support, storage functions, and as the major interface between the plant and various biotic and abiotic factors in the soil environment. Therefore, understanding the development and architecture of roots holds potential for the manipulation of root traits to improve the productivity and sustainability of agricultural systems and to better understand and manage natural ecosystems. While lateral root development is a traceable process along the primary root and different stages can be found along this longitudinal axis of time and development, root system architecture is complex and difficult to quantify. Here, we comment on assays to describe lateral root phenotypes and propose ways to move forward regarding the description of root system architecture, also considering crops and the environment.
Published: 2012

40. Factors affecting the detection distances of reef fish: implications for visual counts

Author: Francis Laloë, Michel Kulbicki, Didier Gascuel, Yves-Marie Bozec, Gérard Mou-Tham, Marine Spatial Ecology Lab, School of BioSciences, Marine Spatial Ecology Lab, School of BioSciences, University of Exeter, University of Exeter-University of Exeter, CoReUS2, Biocomplexité des écosystèmes coralliens de l'Indo-Pacifique (CoReUS2), Gouvernance, Risque, Environnement, Développement (GRED), Université Paul-Valéry - Montpellier 3 (UM3)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), IRD, Écologie et santé des écosystèmes (ESE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Université Paul-Valéry - Montpellier 3 (UPVM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Subjects: 0106 biological sciences, Coral reef fish, STRUCTURE DU PEUPLEMENT, Aquatic Science, Biology, 010603 evolutionary biology, 01 natural sciences, ABONDANCE, POISSON MARIN, COMPTAGE VISUEL, Abundance (ecology), CARACTERE MORPHOLOGIQUE, 14. Life underwater, Transect, DISTRIBUTION SPATIALE, Ecology, Evolution, Behavior and Systematics, Visual census, Distance sampling, Ecology, 010604 marine biology & hydrobiology, fungi, Sampling (statistics), Fishery, RECIF CORALLIEN, [SDV.SA.STP]Life Sciences [q-bio]/Agricultural sciences/Sciences and technics of fishery, %22">Fish , Frequency distribution, METHODOLOGIE
Abstract: Detection patterns of coral reef fish were assessed from the meta-analysis of distance sampling surveys performed by visual census in New Caledonia and French Polynesia, from 1986 to 1999. From approximately 100,000 observations relating to 593 species, the frequency distributions of fish detection distances perpendicular to the transect line were compared according to species characteristics and sampling conditions. The shape and extension of these detection profiles varied markedly with fish size, shyness, and crypticity, indicating strong differences of detectability across species. Detection of very small and cryptic fish decreased strongly 1 m away from the line. Conversely, sightings of shy and large species were excessively low in the first meters due to diver avoidance prior to detection. The larger the fish, the greater the fleeing distance. Distance data underscore how inconsistent detectability biases across species and sites can affect the accuracy of visual censuses when assessing coral reef fish populations.
Published: 2011

41. New insight into the genetic structure of the Allolobophora chlorotica aggregate in Europe using microsatellite and mitochondrial data

Author: Benoit Richard, William Oliver Christian Symondson, Rodolphe Rougerie, Lise Dupont, Alexandre Livet, Thibaud Decaëns, Kevin R. Butt, Robert Andrew King, Jérôme Mathieu, F. Lazrek, David Porco, Biogéochimie et écologie des milieux continentaux (Bioemco), Centre National de la Recherche Scientifique (CNRS)-AgroParisTech-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Recherche Agronomique (INRA)-École normale supérieure - Paris (ENS Paris), Étude et compréhension de la biodiversité (ECODIV), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Cardiff School of Biosciences, Cardiff University, School of Built and Natual Environment, University of Central Lancashire [Preston] (UCLAN), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), School of Biosciences [Cardiff], École normale supérieure - Paris (ENS-PSL), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS)
Subjects: 0106 biological sciences, Genetics, Cryptic diversity DNA barcoding Earthworms Enriched genomic library Microsatellites Population sub-structure, Panmixia, education.field_of_study, genetic structures, Population, Soil Science, Locus (genetics), Allolobophora chlorotica, 04 agricultural and veterinary sciences, Reproductive isolation, Biology, 010603 evolutionary biology, 01 natural sciences, DNA barcoding, Evolutionary biology, Genetic structure, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Microsatellite, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, education, Ecology, Evolution, Behavior and Systematics
Abstract: International audience; The taxonomic status of Allolobophora chlorotica is still the subject of considerable discussion. After the recent experimental demonstration that the two regularly observed colour morphs (pink and green) were not fully interfertile and likely represent two distinct species, molecular analyses revealed a more complex picture with the occurrence of five mitochondrial lineages (named L1 to L5) in A. chlorotica, two within the green morph and three within the pink morph. Although nuclear markers (AFLPs) confirmed that the pink morph might consist of three different taxa, AFLPs data suggested that the green morph may be a single taxon. In order to further characterize the population genetic structure within A. chlorotica in addition to test for reproductive isolation between lineages, eight polymorphic microsatellite loci were developed using a microsatellite-enriched genomic library from an individual belonging to lineage L2. The number of alleles per locus varied from 9 to 29 in a set of individuals belonging to L2. Considerable sub-structure was observed within L2 populations suggesting a low dispersal capability in this species and a distribution of the individuals in patches that could function as panmictic units. These markers were transferable to the other lineages but only five loci could be amplified consistently in four of the lineages (L1, L2, L3 and L4). Microsatellite data confirmed that the green morph represents a single taxon. Although the integrity of the three previously documented lineages within the pink morph was also generally supported by the data, microsatellites provided evidence for hybridization between lineages and between morphs in the field. Moreover, mitochondrial data revealed the existence of two additional mitochondrial lineages within the pink morph. The taxonomic status of the pink morph remains thus unclear, requiring a thorough and comprehensive study.
Published: 2011

42. Two chemically distinct root lignin barriers control solute and water balance

Author: Priya Ramakrishna, David E. Salt, Catherine Lapierre, Guilhem Reyt, Ashley Love, Kris Morreel, Monica Calvo-Polanco, Yann Boursiac, Paulina Flis, Satoshi Fujita, Isai Salas-González, David Tiemessen, Niko Geldner, Wout Boerjan, Gabriel Castrillo, Michael W. George, Future Food Beacon of Excellence & School of Biosciences, Curriculum in Bioinformatics and Computational Biology, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Department of Plant Molecular Biology, Biophore, Université de Lausanne (UNIL), School of Chemistry [Nottingham, UK] (School of Chemistry), University of Nottingham, UK (UON), Institut Jean-Pierre Bourgin (IJPB), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Plant Systems Biology, VIB, and Department of Plant Biotechnology and Bioinformatics, Universiteit Gent = Ghent University [Belgium] (UGENT), Biochimie et Physiologie Moléculaire des Plantes (BPMP), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
Subjects: 0106 biological sciences, 0301 basic medicine, [SDV]Life Sciences [q-bio], Arabidopsis, General Physics and Astronomy, STRIP DIFFUSION BARRIER, 01 natural sciences, Lignin, Plant Roots, Diffusion, chemistry.chemical_compound, CASPARIAN STRIP, RNA-Seq, DEPOSITION, Multidisciplinary, biology, Phenylpropanoid, PARTIAL RESISTANCE, Phenylpropionates, Chemistry, Cell wall, Plant physiology, food and beverages, ARABIDOPSIS, Plants, Genetically Modified, FAMILY, Casparian strip, Science, Genetics and Molecular Biology, macromolecular substances, complex mixtures, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Xylem, LIGNIFICATION, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, BIOSYNTHESIS, TRANSCRIPTION FACTOR MYB15, Arabidopsis Proteins, Cell Membrane, fungi, technology, industry, and agriculture, Biology and Life Sciences, Water, General Chemistry, biology.organism_classification, Plant cell, MEDICAGO-TRUNCATULA, 030104 developmental biology, Microscopy, Fluorescence, Plant signalling, General Biochemistry, Mutation, Biophysics, Endodermis, Secondary metabolism, 010606 plant biology & botany, Transcription Factors
Abstract: Lignin is a complex polymer deposited in the cell wall of specialised plant cells, where it provides essential cellular functions. Plants coordinate timing, location, abundance and composition of lignin deposition in response to endogenous and exogenous cues. In roots, a fine band of lignin, the Casparian strip encircles endodermal cells. This forms an extracellular barrier to solutes and water and plays a critical role in maintaining nutrient homeostasis. A signalling pathway senses the integrity of this diffusion barrier and can induce over-lignification to compensate for barrier defects. Here, we report that activation of this endodermal sensing mechanism triggers a transcriptional reprogramming strongly inducing the phenylpropanoid pathway and immune signaling. This leads to deposition of compensatory lignin that is chemically distinct from Casparian strip lignin. We also report that a complete loss of endodermal lignification drastically impacts mineral nutrients homeostasis and plant growth., Defects in the Casparian strip, a fine band of lignin that seals root endodermal cells and plays roles in nutrient homeostasis, activate a signaling pathway leading to over-lignification. Here, the authors show that this process leads to the deposition of compensatory lignin that is chemically distinct from Casparian strip lignin.
Published: 2021

43. Structure of rat odorant-binding protein OBP1 at 1.6 angstrom resolution

Author: Loïc Briand, David J. Scott, Scott A. White, Antoni J. Borysik, School of Biosciences, University of Birmingham [Birmingham], FLAveur, VIsion et Comportement du consommateur (FLAVIC), Institut National de la Recherche Agronomique (INRA)-Etablissement National d'Enseignement Supérieur Agronomique de Dijon (ENESAD)-Université de Bourgogne (UB), School of Biosciences - National Centre for Macromolecular Hydrodynamics, University of Nottingham, UK (UON), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-Etablissement National d'Enseignement Supérieur Agronomique de Dijon (ENESAD), FLAveur, VIsion et Comportement du consommateur ( FLAVIC ), Etablissement National d'Enseignement Supérieur Agronomique de Dijon ( ENESAD ) -Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ), and University of Nottingham, UK ( UON )
Subjects: Models, Molecular, Olfactory system, Cristallography, Protein Conformation, Recombinant Fusion Proteins, Molecular Sequence Data, Olfaction, OBP1, Crystallography, X-Ray, Receptors, Odorant, 010402 general chemistry, 01 natural sciences, Pheromones, Pichia pastoris, 03 medical and health sciences, [ CHIM.CRIS ] Chemical Sciences/Cristallography, Protein structure, Species Specificity, Structural Biology, ODORANT-BINDING PROTEINS, [CHIM.CRIS]Chemical Sciences/Cristallography, Animals, Amino Acid Sequence, Peptide sequence, 030304 developmental biology, 0303 health sciences, Binding Sites, Sequence Homology, Amino Acid, biology, Proteins, General Medicine, Ligand (biochemistry), biology.organism_classification, Lipocalins, Rats, Cristallographie, 0104 chemical sciences, Transport protein, DNA-Binding Proteins, Biochemistry, Odorant-binding protein, biology.protein, Sequence Alignment
Abstract: The nasal mucosa is a specialist interfacial region sandwiched between the olfactory system and the gaseous chemical milieu. In mammals and insects, this region is rich in odorant-binding proteins that are thought to aid olfaction by assisting mass transfer of the many different organoleptic compounds that make up the olfactory landscape. However, in mammals at least, our grasp on the exact function of odorant-binding proteins is tentative and better insight into the role of these proteins is warranted, not least because of their apparent significance in the olfactory systems of insects. Here, the crystal structure of rat odorant-binding protein 1 is reported at 1.6 Å resolution. This protein is one of the best-characterized mammalian odorant-binding proteins and only the third such protein structure to be solved at high resolution. The protein was crystallized in the holo form and contains an unidentifiable ligand that is probably an artefact from the Pichia pastoris expression system. Comparisons are made between this structure and a modelled OBP1 structure produced using the crystal structure of aphrodisin as a template. Comparisons are also made between OBP1 and the other two rat OBP subtypes, for which crystallographic data are unavailable. Interestingly, we also show that OBP1 is monomeric, which is in contrast to its previous assignment.
Published: 2009

44. Volatile chemical release by bethylid wasps: identity, phylogeny, anatomy and behaviour

Author: Goubault, Marlène, Batchelor, Tim, Romani, Roberto, Linforth, Robert, Fritzsche, Matthias, Francke, Wittko, Hardy, Ian, Institut de recherche sur la biologie de l'insecte UMR7261 (IRBI), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), School of Biological Sciences, Plymouth University, Dipartimento di Scienze Agrarie et Ambientali, Università degli Studi di Perugia (UNIPG), School of BioSciences, University of Nottingham, UK (UON), Organic Chemistry, University of Hamburg, School of Biosciences, and Université de Tours-Centre National de la Recherche Scientifique (CNRS)
Subjects: stomatognathic system, contest behaviour, spiroacetal, skatole, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, mandibular gland, parasitoid, mass spectrometry
Abstract: International audience; The structures of volatile chemicals released by parasitic wasps in the family Bethylidae are shown to correspond to the subfamily to which the species belong. Species in the Epyrinae release skatole (3-methylindole) and species in the Bethylinae release a spiroacetal (2-methyl-1,7-dioxaspiro [5.5]undecane): these compounds are chemically very different. The enantiomeric composition of the spiroacetal differs between congeneric species. Chemical release is a discrete event under the active control of both male and female wasps. Structural differences between the mandibular glands and intramandibular glands suggest the mandibular glands to be the source of released volatiles. Real-time mass spectrometry shows that the spiroacetal is released by Goniozus nephantidis females during dyadic resource contests, with release more common during more aggressive interactions. Chemical tagging with deuterium further shows that the volatile is released by the loser of an agonistic interaction and not the winner. The function of spiroacetal and skatole release by bethylids is discussed.
Published: 2008

45. Changes in dive profiles as an indicator of feeding success in king and Adelie penguins

Author: Charles-André Bost, Patrick J. Butler, Y. Handrich, Andreas Fahlman, Anthony J. Woakes, Yan Ropert-Coudert, Lewis G. Halsey, Centre d'études biologiques de Chizé (CEBC), Centre National de la Recherche Scientifique (CNRS), Département Ecologie, Physiologie et Ethologie (DEPE-IPHC), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Centre for ornithology, School of Biosciences-University of Birmingham [Birmingham], Department of zoology, University of British Columbia (UBC), National Insitute of Polar Research, National Institute of Polar Research [Tokyo] (NiPR), Institut Pluridisciplinaire Hubert Curien (IPHC), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS)-Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Department of Zoology (The University of British Columbia), School of Biosciences, University of Birmingham [Birmingham], and Gaillard, Brigitte
Subjects: 0106 biological sciences, Marine conservation, diving, Bio-logging, 010604 marine biology & hydrobiology, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Foraging, Prey capture, High resolution, Time resolution, Context (language use), Biology, Oceanography, prey capture, 010603 evolutionary biology, 01 natural sciences, [SDE.ES]Environmental Sciences/Environmental and Society, Predation, foraging, penguins, [SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], 14. Life underwater, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Apex predator
Abstract: International audience; Determining when and how deep avian divers feed remains a challenge despite technical advances. Systems that record oesophageal temperature are able to determine rate of prey ingestion with a high level of accuracy but technical problems still remain to be solved. Here we examine the validity of using changes in depth profiles to infer feeding activity in freeranging penguins, as more accessible proxies of their feeding success. We used oesophageal temperature loggers with fast temperature sensors, deployed in tandem with time-depth recorders, on king and Ade´ lie penguins. In the king penguin, a high correspondence was found between the number of ingestions recorded per dive and the number of wiggles during the bottom and the ascent part of the dives. In the Ade´ lie penguins, which feed on smaller prey, the number of large temperature drops was linearly related to the number of undulations per dive. The analysis of change in depth profiles from high-resolution time-depth recorders can provide key information to enhance the study of feeding rate and foraging success of these predators. Such potential is especially relevant in the context of using Southern marine top predators to study change in availability of marine resources.
Published: 2007

46. Is the aquatic macrophyte Crassula helmsii a genuine copper hyperaccumulator?

Author: Antony van der Ent, Amelia Corzo Remigio, Alan J. M. Baker, Mansour Edraki, Centre for Mined Land Rehabilitation, University of Southern Queensland (USQ), Laboratoire Sols et Environnement (LSE), Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), School of BioSciences [Melbourne], Faculty of Science [Melbourne], and University of Melbourne-University of Melbourne
Subjects: inorganic chemicals, 0106 biological sciences, [SDV.SA.AGRO]Life Sciences [q-bio]/Agricultural sciences/Agronomy, Soil Science, chemistry.chemical_element, Plant Science, 01 natural sciences, Crassula helmsii, chemistry.chemical_compound, Aquatic plant, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Hyperaccumulator, ComputingMilieux_MISCELLANEOUS, biology, Phytoextraction, EDDHA, 04 agricultural and veterinary sciences, Hyperaccumulator plant, biology.organism_classification, Copper, 6. Clean water, Crassulaceae, chemistry, Bioaccumulation, Environmental chemistry, Shoot, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, 010606 plant biology & botany
Abstract: Aims: The Australian native hemi-aquatic herb C. helmsii (Crassulaceae) is a copper (Cu) accumulator, tolerant to a wide range of climatic conditions and able to concentrate >9000 μg Cu g−1 in its living tissues. These characteristics suggest practical potential for decontamination of Cu-polluted mine waste waters using a phyto-extraction approach. The aim of this study was to investigate Cu uptake in C. helmsii at different Cu2+ concentrations in solution and to test for the effect of pH on the concentration of free Cu2+ and Cu accumulation in this species. Methods: Different solutions were tested in acid (pH 4.0) and mildly acidic (pH 5.8) conditions at five different Cu2+ concentrations (ranging from 0 to 5 mg Cu L−1). The concentration of free Cu2+ was evaluated using Geochem-EZ software. The distribution of Cu in C. helmsii tissues was examined with micro-X-ray Fluorescence (μXRF) elemental mapping and with Scanning Electron Microscopy with Energy Dispersive X-ray Spectroscopy (SEM-EDS). Results: The highest shoot Cu concentration in C. helmsii was 5870 μg Cu g−1 in the 5 mg Cu L−1 treatment. Copper bioaccumulation was positively correlated with the Cu2+ treatment in the different solutions. The μXRF and SEM-EDS analysis revealed that roots accumulated higher Cu concentrations than the shoots. The concentration of free Cu2+ was shown to be dependent upon the type of Fe-chelator (DTPA, EDDHA, HBED) used in the solution due to the displacement of Fe3+ and complexation of Cu2+. Conclusions: Crassula helmsii is highly tolerant to Cu2+ in solution at acidic and mildly acidic pH, and able to accumulate high Cu concentrations in its tissue. This confirms its potential for applications in Cu phyto-extraction of acidic mine effluent waters high in Cu2+.
Published: 2021

47. The separated electric and magnetic field responses of luminescent bacteria exposed to pulsed microwave irradiation

Author: Lloyd, David [School of Biosciences, Cardiff University, Main Building, Cathays Park, Cardiff, CF10 3AT Wales (United Kingdom)]
Published: 2016
Full Text: View/download PDF

48. Nanoengineering of ferromagnetic palladium in hydrogenase negative mutants of Desulfovibrio fructosovorans

Author: Mikheenko, Iryna P., Mikheenko, P., Sébastien Dementin, Marc Rousset, Macaskie, Lynne E., Unit of Functional Bionanomaterials, School of Biosciences, University of Birmingham [Birmingham], University of Oslo (UiO), Bioénergétique et Ingénierie des Protéines (BIP ), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Microbiologie de la Méditerranée (IMM), and School of Biosciences
Subjects: [SDV]Life Sciences [q-bio], [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
Published: 2005

49. Rotaxanating Metallo-supramolecular Nano-cylinder Helicates to Switch DNA Junction Binding

Author: Aditya Garai, Fillipe V. Rocha, Mauro A. Lima, Nikolas J. Hodges, Viktoriia Sadovnikova, Florian Burkert, Lazaros Melidis, Lucia Cardo, Douglas F. Browning, Roselyne Rosas, James S. Craig, Louise Male, Simin Liu, Ross T Egan, Catherine A J Hooper, Fengbo Liu, Michael J. Hannon, David Bardelang, School of Chemistry [Birmingham], University of Birmingham [Birmingham], Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK, School of Biosciences, Spectropôle - Aix Marseille Université (AMU SPEC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), The State Key Laboratory of Refractories and Metallurgy, School of Materials and Metallurgy, Wuhan University of Science and Technology, Wuhan 430081, People’s Republic of China, Universidade Federal de São Carlos [São Carlos] (UFSCar), Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), School of Chemistry & Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK, Aix Marseille Univ, CNRS, Centrale Marseille, FSCM, Spectropole, Marseille, France, and Department of Chemistry, Federal University of São Carlos
Subjects: Bridged-Ring Compounds, Rotaxane, Rotaxanes, Supramolecular chemistry, Ligands, 010402 general chemistry, Branching (polymer chemistry), 01 natural sciences, Biochemistry, Kinetic control, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, Coordination Complexes, Nano, [CHIM]Chemical Sciences, Cylinder, Chemistry, Tree trunk, Imidazoles, DNA, General Chemistry, Nanostructures, 0104 chemical sciences, Crystallography, Metals
Abstract: A class of rotaxane is created, not by encapsulating a conventional linear thread, but rather by wrapping a large cucurbit[10]uril macrocycle about a three-dimensional, cylindrical, nanosized, self-assembled supramolecular helicate as the axle. The resulting pseudo-rotaxane is readily converted into a proper interlocked rotaxane by adding branch points to the helicate strands that form the surface of the cylinder (like branches and roots on a tree trunk). The supramolecular cylinder that forms the axle is itself a member of a unique and remarkable class of helicate metallo-drugs that bind Y-shaped DNA junction structures and induce cell death. While pseudo-rotaxanation does not modify the DNA-binding properties, proper, mechanically-interlocked rotaxanation transforms the DNA-binding and biological activity of the cylinder. The ability of the cylinder to de-thread from the rotaxane (and thus to bind DNA junction structures) is controlled by the extent of branching: fully-branched cylinders are locked inside the cucurbit[10]uril macrocycle, while cylinders with incomplete branch points can de-thread from the rotaxane in response to competitor guests. The number of branch points can thus afford kinetic control over the drug de-threading and release.
Published: 2020

50. A network of transcriptional repressors modulates auxin responses

Author: Simon Bellows, François Parcy, Anthony Bishopp, Etienne Farcot, Siobhan M. Brady, Margot E. Smit, Jekaterina Truskina, Arnaud Stigliani, Malcolm J. Bennett, Anne Maarit Bågman, Teva Vernoux, Géraldine Brunoud, Silvana Porco, Ari Pekka Mähönen, Julien Macé, Jingyi Han, Ondřej Smetana, Elina Chrysanthou, Carlos S. Galvan-Ampudia, Jonathan Legrand, François Roudier, Stéphanie Lainé, University of Nottingham, School of Biosciences, University of Nottingham, UK (UON), Reproduction et développement des plantes (RDP), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), School of Mathematical Sciences, University of Nottingham, University of California Davis - Department of Plant Biology, University of California (UC), Genome Center [UC Davis], University of California [Davis] (UC Davis), University of California (UC)-University of California (UC), HiLIFE - Institute of Biotechnology [Helsinki] (BI), Helsinki Institute of Life Science (HiLIFE), Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Organismal and Evolutionary Biology Research Program, Faculty of Biological and Environmental Sciences, Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsingin yliopisto = Helsingfors universitet = University of Helsinki-Helsinki Institute of Life Science (HiLIFE), Régulateurs du développement de la fleur (Flo_RE ), Physiologie cellulaire et végétale (LPCV), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), Human Frontier Science Program organization (HFSP) grant RPG0054-2013, Royal Society University Research Fellowship and enhancement award (UF110249 and RGF\EA\180308), Aux-ID CNRS PICS grant, ANR-14-CE11-0018,SERRATIONS,Comprendre les mécanismes de signalisation de l'auxine dans la morphogenèse foliaire(2014), ANR-11-IDEX-0007,Avenir L.S.E.,PROJET AVENIR LYON SAINT-ETIENNE(2011), ANR-10-LABX-0049,GRAL,Grenoble Alliance for Integrated Structural Cell Biology(2010), ANR-17-EURE-0003,CBH-EUR-GS,CBH-EUR-GS(2017), ANR-18-CE12-0014,ChromAuxi,Décodage de la réponse auxine à l'interface ARFs-chromatine(2018), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), University of California, University of California-University of California, University of Helsinki-University of Helsinki, and University of Helsinki-University of Helsinki-Helsinki Institute of Life Science (HiLIFE)
Subjects: 0106 biological sciences, Transcription, Genetic, Mutant, Arabidopsis, Gene regulatory network, Down-Regulation, Repressor, Biology, Genes, Plant, 01 natural sciences, 03 medical and health sciences, Gene Expression Regulation, Plant, Auxin, Transcription (biology), Two-Hybrid System Techniques, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Gene Regulatory Networks, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Gene, 030304 developmental biology, chemistry.chemical_classification, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Indoleacetic Acids, Arabidopsis Proteins, fungi, food and beverages, Chromatin, Cell biology, Repressor Proteins, chemistry, Mutation, 010606 plant biology & botany
Abstract: International audience; The regulation of signalling capacity, combined with the spatiotemporal distribution of developmental signals themselves, is pivotal in setting developmental responses in both plants and animals1. The hormone auxin is a key signal for plant growth and development that acts through the AUXIN RESPONSE FACTOR (ARF) transcription factors2-4. A subset of these, the conserved class A ARFs5, are transcriptional activators of auxin-responsive target genes that are essential for regulating auxin signalling throughout the plant lifecycle2,3. Although class A ARFs have tissue-specific expression patterns, how their expression is regulated is unknown. Here we show, by investigating chromatin modifications and accessibility, that loci encoding these proteins are constitutively open for transcription. Through yeast one-hybrid screening, we identify the transcriptional regulators of the genes encoding class A ARFs from Arabidopsis thaliana and demonstrate that each gene is controlled by specific sets of transcriptional regulators. Transient transformation assays and expression analyses in mutants reveal that, in planta, the majority of these regulators repress the transcription of genes encoding class A ARFs. These observations support a scenario in which the default configuration of open chromatin enables a network of transcriptional repressors to regulate expression levels of class A ARF proteins and modulate auxin signalling output throughout development.
Published: 2020

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