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5 results on '"Schreuders, Jeannette"'

2. Abstract 1716: Anticancer activity of the taxane nanoparticles, DEP® docetaxel and DEP® cabazitaxel

Author

Kelly, Brian D., primary, McLeod, Victoria, additional, Walker, Rachael, additional, Schreuders, Jeannette, additional, Jackson, Susan, additional, Giannis, Michael, additional, Dietinger, Christine, additional, Reitano, Pauline, additional, Pathak, Rashmi, additional, Xia, Shirley, additional, Cargill, Anne, additional, Seta, Aynaz, additional, Hufton, Richard, additional, Heery, Graham, additional, Cullinane, Carleen, additional, and Owen, David J., additional

Published
2020
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3. Abstract 1715: Anti-cancer activity of a SN-38 nanoparticle, DEP® irinotecan, in human colon cancer xenograft models

Author

Kelly, Brian D., primary, McLeod, Victoria, additional, Walker, Rachael, additional, Schreuders, Jeannette, additional, Jackson, Susan, additional, Giannis, Michael, additional, Dietinger, Christine, additional, Xia, Shirley, additional, Cargill, Anne, additional, Seta, Aynaz, additional, Hufton, Richard, additional, Heery, Graham, additional, Cullinane, Carleen, additional, and Owen, David J., additional

Published
2020
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4. A fluorescent histone deacetylase (HDAC) inhibitor for cellular imaging

Author

Fleming, Cassandra L., Ashton, Trent D., Nowell, Cameron, Devlin, Mark, Natoli, Anthony, Schreuders, Jeannette, Pfeffer, Frederick M., Fleming, Cassandra L., Ashton, Trent D., Nowell, Cameron, Devlin, Mark, Natoli, Anthony, Schreuders, Jeannette, and Pfeffer, Frederick M.

Abstract

Fluorescence microscopy studies using 4-morpholinoscriptaid (4MS) demonstrated rapid cellular uptake of this scriptaid analogue into the cytoplasm but no nuclear penetration. As 4MS and scriptaid have the same in vitro activity against HDACs and KASUMI-1 cells; 4MS exemplifies a rational approach to subtly modify ‘profluorogenic’ substrates for intracellular studies.

Published
2015

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