231 results on '"Schwardt, Oliver"'
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2. Simultaneous quantification of atorvastatin, erlotinib and OSI-420 in rat serum and liver microsomes using a novel liquid chromatography-mass spectrometry method
3. Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics
4. Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation
5. 158 Structure-guided design of derivatives of the complement inhibitor compstatin with improved species specificity profiles
6. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics
7. 2-C-Branched mannosides as a novel family of FimH antagonists—Synthesis and biological evaluation
8. SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
9. Prodruggability of carbohydrates--oral FimH antagonists
10. Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
11. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewis x Mimetics.
12. Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022)
13. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties
14. A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN
15. Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists
16. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
17. Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside
18. Kinetic and thermodynamic properties of MAG antagonists
19. Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein
20. Probing the carbohydrate recognition domain of E-selectin: The importance of the acid orientation in sLe x mimetics
21. Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic
22. Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)
23. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
24. A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewisx
25. Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?
26. Trivalent, Gal/Gal NAc-containing ligands designed for the asialoglycoprotein receptor
27. Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside.
28. SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
29. Mimetics of the tri- and tetrasaccharide epitope of GQ1bα as myelin-associated glycoprotein (MAG) ligands
30. Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)
31. A Potent Mimetic of the Siglec‐8 Ligand 6’‐Sulfo‐Sialyl Lewisx
32. Drug Discovery Today
33. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties.
34. Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics
35. Carbohydrate Mimetics in Drug Discovery
36. Synthesis of aryl sialosides using Mitsunobu conditions
37. Comparison of affinity ranking by target-directed dynamic combinatorial chemistry and surface plasmon resonance
38. Front Cover: Improvement of Aglycone π‐Stacking Yields Nanomolar to Sub‐nanomolar FimH Antagonists (ChemMedChem 7/2019)
39. Improvement of Aglycone π‐Stacking Yields Nanomolar to Sub‐nanomolar FimH Antagonists
40. A Potent Mimetic of the Siglec‐8 Ligand 6'‐Sulfo‐Sialyl Lewisx.
41. Target‐directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target
42. Urinary Tract Infection: Which Conformation of the Bacterial Lectin FimH Is Therapeutically Relevant?
43. Back Cover: The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target? (ChemBioChem 11/2016)
44. The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?
45. FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability
46. The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X‐ray Crystallography
47. FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile
48. Development of an aggregation assay to screen FimH antagonists
49. FimH antagonists – solubility vs. permeability
50. Kinetic Properties of Carbohydrate–Lectin Interactions: FimH Antagonists
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