1. Nutricatt protocol improves body composition and clinical outcomes in elderly patients undergoing colorectal surgery in eras program: A retrospective cohort study
- Author
-
Rinninella, Emanuele, Biondi, Alberto, Cintoni, M., Raoul, Pauline Celine, Scialanga, Francesca, Persichetti, Eleonora, Pulcini, Gabriele, Pezzuto, R., Persiani, Roberto, D'Ugo, Domenico, Gasbarrini, Antonio, Mele, Maria Cristina, Rinninella E. (ORCID:0000-0002-9165-2367), Biondi A. (ORCID:0000-0002-2470-7858), Raoul P., Scialanga F., Persichetti E., Pulcini G., Persiani R. (ORCID:0000-0002-1537-5097), D'ugo D. (ORCID:0000-0001-6657-6318), Gasbarrini A. (ORCID:0000-0002-7278-4823), Mele M. C. (ORCID:0000-0003-0153-5819), Rinninella, Emanuele, Biondi, Alberto, Cintoni, M., Raoul, Pauline Celine, Scialanga, Francesca, Persichetti, Eleonora, Pulcini, Gabriele, Pezzuto, R., Persiani, Roberto, D'Ugo, Domenico, Gasbarrini, Antonio, Mele, Maria Cristina, Rinninella E. (ORCID:0000-0002-9165-2367), Biondi A. (ORCID:0000-0002-2470-7858), Raoul P., Scialanga F., Persichetti E., Pulcini G., Persiani R. (ORCID:0000-0002-1537-5097), D'ugo D. (ORCID:0000-0001-6657-6318), Gasbarrini A. (ORCID:0000-0002-7278-4823), and Mele M. C. (ORCID:0000-0003-0153-5819)
- Abstract
Background: A poor body composition, often found in elderly patients, negatively impacts perioperative outcomes. We evaluated the effect of a perioperative nutritional protocol (NutriCatt) on body composition and clinical outcomes in a cohort of elderly patients undergoing colorectal surgery in a high-volume center adopting the ERAS program. Methods: 302 out of 332 elderly (>75 years) patients from 2015 to 2020 were identified. Patients were divided according to their adherence, into “NutriCatt + ERAS” (n = 166) or “standard ERAS” patients (n = 136). Anthropometric and bioelectrical impedance analysis data were evaluated for NutriCatt + ERAS patients. Complications, length of hospital stay (LOS), and other postoperative outcomes were compared between both groups. Results: In NutriCatt + ERAS patients, significant improvements of phase angle (pre-admission vs. admission 4.61 ± 0.79 vs. 4.84 ± 0.85; p = 0.001; pre-admission vs. discharge 4.61 ± 0.79 vs. 5.85 ± 0.73; p = 0.0002) and body cell mass (pre-admission vs. admission 22.4 ± 5.6 vs. 23.2 ± 5.7; p = 0.03; preadmission vs. discharge 22.4 ± 5.6 vs. 23.1 ± 5.8; p = 0.02) were shown. NutriCatt + ERAS patients reported reduced LOS (p = 0.03) and severe complications (p = 0.03) compared to standard ERAS patients. A regression analysis confirmed the protective effect of the NutriCatt protocol on severe complications (OR 0.10, 95% CI 0.01–0.56; p = 0.009). Conclusions: The NutriCatt protocol improves clinical outcomes in elderly patients and should be recommended in ERAS colorectal surgery.
- Published
- 2021