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11 results on '"Scioccati, L"'

3. Changing Antimicrobial Resistance Profiles among Neisseria gonorrhoeae Isolates in Italy, 2003 to 2012

Author

Carannante, Anna, Renna, Giovanna, Dal Conte, Ivano, Ghisetti, Valeria, Matteelli, Alberto, Prignano, Grazia, Impara, Giampaolo, Cusini, Marco, D'Antuono, Antonietta, Vocale, Caterina, Antonetti, Raffaele, Gaino, Marina, Busetti, Marina, Latino, Maria Agnese, Mencacci, Antonella, Bonanno, Carmen, Cava, Maria Carmela, Giraldi, Cristina, Stefanelli, Paola, Del Re, S., Milano, R., Di Carlo, A., Cristaudo, A., Palamara, G., Scioccati, L., Ramoni, S., DE FRANCESCO, Maria Antonia, Sambri, V., Landini, M. P., Cavrini, F., Fiore, J., Di Taranto, A., De Nittis, R., Predazzer, R., Ober, P., Urbani, F., Petix, V., Rossi, T., Pauri, P., Meucci, M., Tagliaferro, L., Colaci, C., Carannante, Anna, Renna, Giovanna, Conte, Ivano Dal, Ghisetti, Valeria, Matteelli, Alberto, Prignano, Grazia, Impara, Giampaolo, Cusini, Marco, D'Antuono, Antonietta, Vocale, Caterina, Antonetti, Raffaele, Gaino, Marina, Busetti, Marina, Latino, Maria Agnese, Mencacci, Antonella, Bonanno, Carmen, La Cava, Maria Carmela, Giraldi, Cristina, and Stefanelli, Paola

Subjects
Male, Anti-Bacterial Agents, Azithromycin, Cefixime, Ciprofloxacin, Humans, Italy, Neisseria gonorrhoeae, Penicillinase, Penicillins, Retrospective Studies, Tetracycline, Pharmacology (medical), Pharmacology, Infectious Diseases, Gonorrhea, Infectious Disease, Biology, medicine.disease_cause, urologic and male genital diseases, Microbiology, Epidemiology and Surveillance, Antibiotic resistance, Retrospective Studie, Anti-Bacterial Agent, medicine, Etest, Medicine (all), Penicillin, Antimicrobial, medicine.disease, Virology, Human, medicine.drug
Abstract

The emergence of Neisseria gonorrhoeae isolates displaying resistance to antimicrobial agents is a major public health concern and a serious issue related to the occurrence of further untreatable gonorrhea infections. A retrospective analysis on 1,430 N. gonorrhoeae isolates, collected from 2003 through 2012, for antimicrobial susceptibility by Etest and molecular characterization by Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) was carried out in Italy. Azithromycin-resistant gonococci decreased from 14% in 2007 to 2.2% in 2012. Similarly, isolates with high MICs to cefixime (>0.125 mg/liter) decreased from 11% in 2008 to 3.3% in 2012. The ciprofloxacin resistance rate remains quite stable, following an increasing trend up to 64% in 2012. The percentage of penicillinase-producing N. gonorrhoeae (PPNG) significantly declined from 77% in 2003 to 7% in 2012. A total of 81 multidrug-resistant (MDR) gonococci were identified, showing 11 different antimicrobial resistance patterns. These were isolated from men who have sex with men (MSM) and from heterosexual patients. Two sequence types (STs), ST661 and ST1407, were the most common. Genogroup 1407, which included cefixime-, ciprofloxacin-, and azithromycin-resistant isolates, was found. In conclusion, a change in the antimicrobial resistance profiles among gonococci was identified in Italy together with a percentage of MDR isolates.

Published
2014

5. Pemfigo: percorsi diagnostici e monitoraggio sierologico

Author

Vezzoli, P., Usuelli, V., Marangio, V., Fanoni, D., Scioccati, L., Alessi, E., and Berti, E.

Subjects
diagnosi, Settore MED/35 - Malattie Cutanee e Veneree, Pemfigo, immunofluorescenza diretta, tests sierologici, ELISA
Published
2007

6. Seroprevalence of herpes simplex virus type 2 infection among attendees of a sexually transmitted disease clinic in Italy. Italian Herpes Forum

Author

Cusini, M, Cusan, M, Parolin, C, Scioccati, L, Decleva, I, Mengoli, C, Suligoi, B, Palú, G, and Gentile, G

Subjects
Adult, Male, Herpes Genitalis, Adolescent, Blotting, Herpesvirus 2, Sexually Transmitted Diseases, Enzyme-Linked Immunosorbent Assay, Middle Aged, Ambulatory Care Facilities, Sensitivity and Specificity, Antibodies, Aged, Antibodies, Viral, Blotting, Western, Cross-Sectional Studies, Female, Herpesvirus 2, Human, Humans, Italy, Seroepidemiologic Studies, Viral, Western, Human
Published
2000

8. TPHA test. Experience at the Clinic of Dermatology, University of Milan.

Author

Alessi, E and Scioccati, L

Abstract

The results of serological investigations with the treponemal haemagglutination (TPHA) test are reported in a large number of luetic and non-luetic patients. From these the following conclusions can be drawn: (1) The sensitivity of the TPHA test is decreased if the test is carried out with micromethods; however, in our opinion, the same degree of sensitivity can be obtained either with the macromethod at dilution 1/80-1/60 or with micromethods at 1/20-1/40. (2) The sensitivity of this test is high, being similar to that of the fluorescent treponemal antibody absorption (FTA-ABS) test in primary and secondary syphilis and even higher than that of the FTA-ABS test in treated subjects. (3) The specificity of the reaction is high, as demonstrated by examining sera in patients with a negative history and clinical examination together with negative results to Treponema pallidum immobilisation (TPI) and FTA-ABS tests, and by studying biological false positive sera. (4) For the serological screening, it may be sufficient to perform the TPHA test with the 1/20-1/40 micromethod together with the Venereal Disease Research Laboratory (VDRL) test. In patients with suspected syphilis, it is advisable to perform the TPHA test by the macromethod, in combination with the FTA-ABS test. [ABSTRACT FROM PUBLISHER]

Published
1978
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10. [Treponemal hemagglutination test (TPHA). Validity of the micromethod using dilutions of sera 1/20-1/40].

Author

Alessi E and Scioccati L

Subjects
Humans, Hemagglutination Tests, Syphilis Serodiagnosis, Treponema pallidum
Abstract

The Authors studied the possibility to use, for the carrying out of the TPHA micromethod, higher serum dilutions, as preliminary investigations had pointed out an insufficient sensitivity of the reaction performed at the 1:80 - 1:160 dilutions, particularly in the primary-secondary phase of the luetic infection. The Authors controlled, preliminarily, that at the dilutions studied, no unacceptable increase of spontaneous hemagglutinations and false positive reactions took place in the test sera. The investigation stressed the acceptability of the methodological modification set forth.

Published
1977

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