Search

Your search keyword '"Scott, Nicole"' showing total 583 results
Start Over Author "Scott, Nicole"
583 results on '"Scott, Nicole"'

1. De-escalation of Disease-Modifying Therapy for People with Multiple Sclerosis Due to Safety Considerations: Characterizing 1-Year Outcomes in 25 People Who Switched from Ocrelizumab to Diroximel Fumarate

Author

Gudesblatt, Mark, Bumstead, Barbara, Buhse, Marijean, Zarif, Myassar, Morrow, Sarah A., Nicholas, Jacqueline A., Hancock, Laura M., Wilken, Jeffrey, Weller, Joanna, Scott, Nicole, Gocke, Anne, Lewin, James B., Kaczmarek, Olivia, Mendoza, Jason P., and Golan, Daniel

Published
2024
Full Text
View/download PDF

2. Current challenges and future of agricultural genomes to phenomes in the USA

Author

Tuggle, Christopher K., Clarke, Jennifer L., Murdoch, Brenda M., Lyons, Eric, Scott, Nicole M., Beneš, Bedrich, Campbell, Jacqueline D., Chung, Henri, Daigle, Courtney L., Das Choudhury, Sruti, Dekkers, Jack C. M., Dórea, Joao R. R., Ertl, David S., Feldman, Max, Fragomeni, Breno O., Fulton, Janet E., Guadagno, Carmela R., Hagen, Darren E., Hess, Andrew S., Kramer, Luke M., Lawrence-Dill, Carolyn J., Lipka, Alexander E., Lübberstedt, Thomas, McCarthy, Fiona M., McKay, Stephanie D., Murray, Seth C., Riggs, Penny K., Rowan, Troy N., Sheehan, Moira J., Steibel, Juan P., Thompson, Addie M., Thornton, Kara J., Van Tassell, Curtis P., and Schnable, Patrick S.

Published
2024
Full Text
View/download PDF

4. Characterizing opioid overdose hotspots for place-based overdose prevention and treatment interventions: A geo-spatial analysis of Rhode Island, USA

Author

Samuels, Elizabeth A., Goedel, William C., Jent, Victoria, Conkey, Lauren, Hallowell, Benjamin D., Karim, Sarah, Koziol, Jennifer, Becker, Sara, Yorlets, Rachel R., Merchant, Roland, Keeler, Lee Ann, Reddy, Neha, McDonald, James, Alexander-Scott, Nicole, Cerda, Magdalena, and Marshall, Brandon D.L.

Published
2024
Full Text
View/download PDF

10. Change in Disease Modifying Therapy from DMF to DRF in People with Multiple Sclerosis and the Impact on CD4/CD8 T Cells (P8-6.016)

Author

Rahaman, Fatema, primary, Jo, Matthew, additional, Weller, Joanna, additional, Kaczmarek, Olivia, additional, Jaenicke, Kaitlyn, additional, Baek, Steven, additional, Buhse, Marijean, additional, Bumstead, Barbara, additional, Zarif, Myassar, additional, Mendoza, Jason, additional, Smrtka, Jennifer, additional, Scott, Nicole, additional, Lewin, James, additional, and Gudesblatt, Mark, additional

Published
2024
Full Text
View/download PDF

17. Satellite remote sensing data can be used to model marine microbial metabolite turnover.

Author

Larsen, Peter E, Scott, Nicole, Post, Anton F, Field, Dawn, Knight, Rob, Hamada, Yuki, and Gilbert, Jack A

Subjects
Humans, Bacteria, RNA, Ribosomal, 16S, Water Microbiology, Seawater, Environmental Monitoring, Models, Biological, Geographic Information Systems, England, Oceans and Seas, Satellite Imagery, Genetics, Microbiology, Environmental Sciences, Biological Sciences, Technology
Abstract

Sampling ecosystems, even at a local scale, at the temporal and spatial resolution necessary to capture natural variability in microbial communities are prohibitively expensive. We extrapolated marine surface microbial community structure and metabolic potential from 72 16S rRNA amplicon and 8 metagenomic observations using remotely sensed environmental parameters to create a system-scale model of marine microbial metabolism for 5904 grid cells (49 km(2)) in the Western English Chanel, across 3 years of weekly averages. Thirteen environmental variables predicted the relative abundance of 24 bacterial Orders and 1715 unique enzyme-encoding genes that encode turnover of 2893 metabolites. The genes' predicted relative abundance was highly correlated (Pearson Correlation 0.72, P-value

Published
2015

18. Metagenomic analysis of microbial consortium from natural crude oil that seeps into the marine ecosystem offshore Southern California

Author

Hawley, Erik R, Piao, Hailan, Scott, Nicole M, Malfatti, Stephanie, Pagani, Ioanna, Huntemann, Marcel, Chen, Amy, Glavina del Rio, Tijana, Foster, Brian, Copeland, Alex, Jansson, Janet, Pati, Amrita, Tringe, Susannah, Gilbert, Jack A, Lorenson, Thomas D, and Hess, Matthias

Subjects
Bioremediation, hydrocarbon-degradation, marine ecosystem, crude oil, natural oil seeps, anaerobic methane oxidation, bacteria, archaea, metagenomics
Abstract

Crude oils can be major contaminants of the marine ecosystem and microorganisms play a significant role in the degradation of its main constituents. To increase our understanding of the microbial hydrocarbon degradation process in the marine ecosystem, we collected crude oil from an active seep area located in the Santa Barbara Channel (SBC) and generated a total of about 52 Gb of raw metagenomic sequence data. The assembled data comprised ~500 Mb, representing ~1.1 million genes derived primarily from chemolithoautotrophic bacteria. Members of Oceanospirillales, a bacterial order belonging to the Deltaproteobacteria, recruited less than 2% of the assembled genes within the SBC metagenome. In contrast, the microbial community associated with the oil plume that developed in the aftermath of the Deepwater Horizon (DWH) blowout in 2010, was dominated by Oceanospirillales, which comprised more than 60% of the metagenomic data generated from the DWH oil plume. This suggests that Oceanospirillales might play a less significant role in the microbially mediated hydrocarbon conversion within the SBC seep oil compared to the DWH plume oil. We hypothesize that this difference results from the SBC oil seep being mostly anaerobic, while the DWH oil plume is aerobic. Within the Archaea, the phylum Euryarchaeota, recruited more than 95% of the assembled archaeal sequences from the SBC oil seep metagenome, with more than 50% of the sequences assigned to members of the orders Methanomicrobiales and Methanosarcinales. These orders contain organisms capable of anaerobic methanogenesis and methane oxidation (AOM) and we hypothesize that these orders - and their metabolic capabilities - may be fundamental to the ecology of the SBC oil seep.

Published
2014

19. Genome-wide interaction studies reveal sex-specific asthma risk alleles

Author

Myers, Rachel A, Scott, Nicole M, Gauderman, W James, Qiu, Weiliang, Mathias, Rasika A, Romieu, Isabelle, Levin, Albert M, Pino-Yanes, Maria, Graves, Penelope E, Villarreal, Albino Barraza, Beaty, Terri H, Carey, Vincent J, Croteau-Chonka, Damien C, del Rio Navarro, Blanca, Edlund, Christopher, Hernandez-Cadena, Leticia, Navarro-Olivos, Efrain, Padhukasahasram, Badri, Salam, Muhammad T, Torgerson, Dara G, Van den Berg, David J, Vora, Hita, Bleecker, Eugene R, Meyers, Deborah A, Williams, L Keoki, Martinez, Fernando D, Burchard, Esteban G, Barnes, Kathleen C, Gilliland, Frank D, Weiss, Scott T, London, Stephanie J, Raby, Benjamin A, Ober, Carole, Nicolae, Dan L, Santana, Jose Rodriguez, Cintron, William Rodriguez, Chapela, Rocio, Ford, Jean, Thyne, Shannon, Avila, Pedro C, Monge, Juan Jose Sienra, Boorgula, Meher, Cheadle, Chris, Eng, Celeste S, Kiley, J, Banks-Schlegel, S, and Gan, W

Subjects
Biological Sciences, Genetics, Minority Health, Asthma, Lung, Human Genome, Prevention, Women's Health, Clinical Research, 2.1 Biological and endogenous factors, Inflammatory and immune system, Respiratory, Alleles, Chromosome Mapping, Female, Gene Expression Regulation, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Humans, Male, Odds Ratio, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Racial Groups, Reproducibility of Results, Sex Factors, GRAAD, Medical and Health Sciences, Genetics & Heredity
Abstract

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this has not yet been explored at a genome-wide level. We aimed to identify sex-specific asthma risk alleles by performing a genome-wide scan for genotype-by-sex interactions in the ethnically diverse participants in the EVE Asthma Genetics Consortium. We performed male- and female-specific genome-wide association studies in 2653 male asthma cases, 2566 female asthma cases and 3830 non-asthma controls from European American, African American, African Caribbean and Latino populations. Association tests were conducted in each study sample, and the results were combined in ancestry-specific and cross-ancestry meta-analyses. Six sex-specific asthma risk loci had P-values < 1 × 10(-6), of which two were male specific and four were female specific; all were ancestry specific. The most significant sex-specific association in European Americans was at the interferon regulatory factor 1 (IRF1) locus on 5q31.1. We also identify a Latino female-specific association in RAP1GAP2. Both of these loci included single-nucleotide polymorphisms that are known expression quantitative trait loci and have been associated with asthma in independent studies. The IRF1 locus is a strong candidate region for male-specific asthma susceptibility due to the association and validation we demonstrate here, the known role of IRF1 in asthma-relevant immune pathways and prior reports of sex-specific differences in interferon responses.

Published
2014

20. Longitudinal analysis of microbial interaction between humans and the indoor environment.

Author

Lax, Simon, Smith, Daniel P, Hampton-Marcell, Jarrad, Owens, Sarah M, Handley, Kim M, Scott, Nicole M, Gibbons, Sean M, Larsen, Peter, Shogan, Benjamin D, Weiss, Sophie, Metcalf, Jessica L, Ursell, Luke K, Vázquez-Baeza, Yoshiki, Van Treuren, Will, Hasan, Nur A, Gibson, Molly K, Colwell, Rita, Dantas, Gautam, Knight, Rob, and Gilbert, Jack A

Subjects
Foot, Hand, Nose, Animals, Humans, Bacteria, Beds, Family, Surface Properties, Floors and Floorcoverings, Household Articles, Host-Pathogen Interactions, Metagenome, Pets, Microbiota, Clinical Research, Genetics, Human Genome, Aetiology, 2.2 Factors relating to the physical environment, Infection, Sustainable Cities and Communities, Good Health and Well Being, General Science & Technology
Abstract

The bacteria that colonize humans and our built environments have the potential to influence our health. Microbial communities associated with seven families and their homes over 6 weeks were assessed, including three families that moved their home. Microbial communities differed substantially among homes, and the home microbiome was largely sourced from humans. The microbiota in each home were identifiable by family. Network analysis identified humans as the primary bacterial vector, and a Bayesian method significantly matched individuals to their dwellings. Draft genomes of potential human pathogens observed on a kitchen counter could be matched to the hands of occupants. After a house move, the microbial community in the new house rapidly converged on the microbial community of the occupants' former house, suggesting rapid colonization by the family's microbiota.

Published
2014

21. Metagenomics reveals sediment microbial community response to Deepwater Horizon oil spill.

Author

Mason, Olivia U, Scott, Nicole M, Gonzalez, Antonio, Robbins-Pianka, Adam, Bælum, Jacob, Kimbrel, Jeffrey, Bouskill, Nicholas J, Prestat, Emmanuel, Borglin, Sharon, Joyner, Dominique C, Fortney, Julian L, Jurelevicius, Diogo, Stringfellow, William T, Alvarez-Cohen, Lisa, Hazen, Terry C, Knight, Rob, Gilbert, Jack A, and Jansson, Janet K

Subjects
Gammaproteobacteria, Alteromonadaceae, Nitrogen, Carbon Radioisotopes, Mixed Function Oxygenases, Bacterial Proteins, RNA, Bacterial, RNA, Ribosomal, 16S, Ecosystem, Seawater, Gene Expression, Metagenomics, Gulf of Mexico, Petroleum Pollution, Polycyclic Aromatic Hydrocarbons, DWH oil spill, hydrocarbons, iTag/Metagenomics, microbial community structure, sediments, Genetics, Microbiology, Environmental Sciences, Biological Sciences, Technology
Abstract

The Deepwater Horizon (DWH) oil spill in the spring of 2010 resulted in an input of ∼4.1 million barrels of oil to the Gulf of Mexico; >22% of this oil is unaccounted for, with unknown environmental consequences. Here we investigated the impact of oil deposition on microbial communities in surface sediments collected at 64 sites by targeted sequencing of 16S rRNA genes, shotgun metagenomic sequencing of 14 of these samples and mineralization experiments using (14)C-labeled model substrates. The 16S rRNA gene data indicated that the most heavily oil-impacted sediments were enriched in an uncultured Gammaproteobacterium and a Colwellia species, both of which were highly similar to sequences in the DWH deep-sea hydrocarbon plume. The primary drivers in structuring the microbial community were nitrogen and hydrocarbons. Annotation of unassembled metagenomic data revealed the most abundant hydrocarbon degradation pathway encoded genes involved in degrading aliphatic and simple aromatics via butane monooxygenase. The activity of key hydrocarbon degradation pathways by sediment microbes was confirmed by determining the mineralization of (14)C-labeled model substrates in the following order: propylene glycol, dodecane, toluene and phenanthrene. Further, analysis of metagenomic sequence data revealed an increase in abundance of genes involved in denitrification pathways in samples that exceeded the Environmental Protection Agency (EPA)'s benchmarks for polycyclic aromatic hydrocarbons (PAHs) compared with those that did not. Importantly, these data demonstrate that the indigenous sediment microbiota contributed an important ecosystem service for remediation of oil in the Gulf. However, PAHs were more recalcitrant to degradation, and their persistence could have deleterious impacts on the sediment ecosystem.

Published
2014

24. Human and environmental impacts on river sediment microbial communities.

Author

Gibbons, Sean M, Jones, Edwin, Bearquiver, Angelita, Blackwolf, Frederick, Roundstone, Wayne, Scott, Nicole, Hooker, Jeff, Madsen, Robert, Coleman, Maureen L, and Gilbert, Jack A

Subjects
Humans, RNA, Ribosomal, 16S, Biodiversity, Rivers, Geologic Sediments, RNA, Ribosomal, 16S, General Science & Technology
Abstract

Sediment microbial communities are responsible for a majority of the metabolic activity in river and stream ecosystems. Understanding the dynamics in community structure and function across freshwater environments will help us to predict how these ecosystems will change in response to human land-use practices. Here we present a spatiotemporal study of sediments in the Tongue River (Montana, USA), comprising six sites along 134 km of river sampled in both spring and fall for two years. Sequencing of 16S rRNA amplicons and shotgun metagenomes revealed that these sediments are the richest (∼ 65,000 microbial 'species' identified) and most novel (93% of OTUs do not match known microbial diversity) ecosystems analyzed by the Earth Microbiome Project to date, and display more functional diversity than was detected in a recent review of global soil metagenomes. Community structure and functional potential have been significantly altered by anthropogenic drivers, including increased pathogenicity and antibiotic metabolism markers near towns and metabolic signatures of coal and coalbed methane extraction byproducts. The core (OTUs shared across all samples) and the overall microbial community exhibited highly similar structure, and phylogeny was weakly coupled with functional potential. Together, these results suggest that microbial community structure is shaped by environmental drivers and niche filtering, though stochastic assembly processes likely play a role as well. These results indicate that sediment microbial communities are highly complex and sensitive to changes in land use practices.

Published
2014

25. The microbial nitrogen cycling potential is impacted by polyaromatic hydrocarbon pollution of marine sediments

Author

Scott, Nicole M, Hess, Matthias, Bouskill, Nick J, Mason, Olivia U, Jansson, Janet K, and Gilbert, Jack A

Subjects
Microbiology, Biological Sciences, nitrogen cycling, marine sediments, denitrification, microbial ecology, metagenomics, deepwater horizon oil spill, oil contamination, oil seeps, Environmental Science and Management, Soil Sciences, Medical microbiology
Abstract

During hydrocarbon exposure, the composition and functional dynamics of marine microbial communities are altered, favoring bacteria that can utilize this rich carbon source. Initial exposure of high levels of hydrocarbons in aerobic surface sediments can enrich growth of heterotrophic microorganisms having hydrocarbon degradation capacity. As a result, there can be a localized reduction in oxygen potential within the surface layer of marine sediments causing anaerobic zones. We hypothesized that increasing exposure to elevated hydrocarbon concentrations would positively correlate with an increase in denitrification processes and the net accumulation of dinitrogen. This hypothesis was tested by comparing the relative abundance of genes associated with nitrogen metabolism and nitrogen cycling identified in 6 metagenomes from sediments contaminated by polyaromatic hydrocarbons from the Deepwater Horizon (DWH) oil spill in the Gulf of Mexico, and 3 metagenomes from sediments associated with natural oil seeps in the Santa Barbara Channel. An additional 8 metagenomes from uncontaminated sediments from the Gulf of Mexico were analyzed for comparison. We predicted relative changes in metabolite turnover as a function of the differential microbial gene abundances, which showed predicted accumulation of metabolites associated with denitrification processes, including anammox, in the contaminated samples compared to uncontaminated sediments, with the magnitude of this change being positively correlated to the hydrocarbon concentration and exposure duration. These data highlight the potential impact of hydrocarbon inputs on N cycling processes in marine sediments and provide information relevant for system scale models of nitrogen metabolism in affected ecosystems.

Published
2014

26. Investing in Public Health and Community Partnerships Reduced COVID-19–Related Disparities.

Author

Mullen, Jewel M. and Alexander-Scott, Nicole

Subjects
*HEALTH services accessibility, *SERIAL publications, *INTERPROFESSIONAL relations, *ENDOWMENTS, *OCCUPATIONAL roles, *PUBLIC relations, *CREATIVE ability, *PUBLIC health, *HEALTH equity, *COVID-19
Abstract

The authors explore the strategies stated in the supplement "Lessons Learned From the Centers for Disease Control and Prevention's National Initiative to Address COVID-19 Health Disparities Among Populatoins at High-Risk and Underserved," published by the U.S. Centers for Disease Control and Prevention in partnership with the National Network for Public Health Improvement. Topics discussed include research articles that showed pitfalls of applying data-driven approaches to reducing inequities.

Published
2024
Full Text
View/download PDF

33. Morphological, ultrastructural, genetic characteristics and remarkably low prevalence of macroscopic Sarcocystis species isolated from sheep and goats in Kurdistan region, Iraq

Author

Nawshirwan, Salh, primary, Heucken, Nicole, additional, Piekarek, Nadin, additional, van Beers, Tim, additional, Fulgham-Scott, Nicole, additional, Grandoch, Andrea, additional, Neiss, Wolfram F., additional, Vogt, Johannes, additional, and Barham, Mohammed, additional

Published
2023
Full Text
View/download PDF

38. Resident Research Mentoring Teams: A Support Program to Increase Resident Research Productivity

Author

Haas, David M., Hadaie, Bachar, Ramirez, Mirian, Shanks, Anthony L., and Scott, Nicole P.

Subjects
Original Research
Abstract

BACKGROUND: Scholarly activity is a requirement for most graduate medical education training programs. However, barriers exist for residents to accomplish projects. OBJECTIVE: To evaluate the correlation between a resident research mentoring team (RRMT) program and meeting presentations and publications of resident research projects. We further plan to report feasibility of the RRMT. METHODS: We performed a before-and-after study of meeting presentations and/or publication of resident research projects before institution of the RRMT (2004-2011) and post-RRMT implementation (2016-2019). The RRMT is a diverse group of faculty, statisticians, and research staff who meet regularly with residents to provide guidance for their research studies. It is part of overall research support from the department, which also includes biostatistics, database and regulatory help, travel funds, and project budget funds. Data on meeting presentations and publications were collected from Google Scholar, PubMed, Scopus, and the IUPUI ScholarWorks institutional repository, using resident and faculty names and titles of projects. Comparisons of pre- and post-RRMT groups were made. RESULTS: Seventy-four residents were in the pre-RRMT group and 40 were in the post-RRMT group. Post-RRMT residents published, presented, and combined published or presented their projects more frequently than those in pre-RRMT group (57.5% vs 28.4%, P=.002; 50% vs 16.2%, P=.001; 67.5% vs 37.8%, P=.002). Controlling for winning a Research Day award and pursuing a fellowship, being in the post-RRMT group was independently associated with presentation or publication of the resident research project (OR 3.62, 95% CI 1.57-8.83). CONCLUSIONS: Support of resident scholarly activity, such as thorough implementation of a program like the RRMT, is associated with increased presentations and publications of research projects.

Published
2023

40. Change Is Inevitable.

Author

SCOTT, NICOLE

Subjects
*SECULAR humanism, *SOCIAL change
Published
2024

42. Current Challenges and Future of Agricultural Genomes to Phenomes in the U.S.

Author

Tuggle, Christopher K., primary, Clarke, Jennifer, additional, Murdoch, Brenda M, additional, Lyons, Eric, additional, Scott, Nicole M., additional, Benes, Bedrich, additional, Campbell, Jacqueline, additional, Chung, Henri, additional, Daigle, Courtney L., additional, Choudhury, Sruti Das, additional, Dekkers, Jack, additional, Dorea, Joao, additional, Ertl, David, additional, Feldman, Max, additional, Fragomeni, Breno, additional, Fulton, Janet, additional, Guadagno, Carmela, additional, Hagen, Darren, additional, Hess, Andrew, additional, Kramer, Luke, additional, Lawrence-Dill, Carolyn J, additional, Lipka, Alexander, additional, Lubberstedt, Thomas, additional, McCarthy, Fiona Maree, additional, McKay, Stephanie, additional, Murray, Seth, additional, Riggs, Penny, additional, Rowan, Troy N., additional, Sheehan, Moira J., additional, Steibel, Juan Pedro, additional, Thompson, Addie M., additional, Thornton, Kara J., additional, Van Tassell, Curtis P., additional, and Schnable, Patrick, additional

Published
2023
Full Text
View/download PDF

43. A communal catalogue reveals Earths multiscale microbial diversity

Author

Thompson, Luke R., Sanders, Jon G., McDonald, Daniel, Amir, Amnon, Ladau, Joshua, Locey, Kenneth J., Prill, Robert J., Tripathi, Anupriya, Gibbons, Sean M., Ackermann, Gail, Navas-Molina, Jose A., Janssen, Stefan, Kopylova, Evguenia, Vzquez-Baeza, Yoshiki, Gonzlez, Antonio, Morton, James T., Mirarab, Siavash, Zech Xu, Zhenjiang, Jiang, Lingjing, Haroon, Mohamed F., Kanbar, Jad, Zhu, Qiyun, Jin Song, Se, Kosciolek, Tomasz, Bokulich, Nicholas A., Lefler, Joshua, Brislawn, Colin J., Humphrey, Gregory, Owens, Sarah M., Hampton-Marcell, Jarrad, Berg-Lyons, Donna, McKenzie, Valerie, Fierer, Noah, Fuhrman, Jed A., Clauset, Aaron, Stevens, Rick L., Shade, Ashley, Pollard, Katherine S., Goodwin, Kelly D., Jansson, Janet K., Gilbert, Jack A., Knight, Rob, Rivera, Jose L. Agosto, Al-Moosawi, Lisa, Alverdy, John, Amato, Katherine R., Andras, Jason, Angenent, Largus T., Antonopoulos, Dionysios A., Apprill, Amy, Armitage, David, Ballantine, Kate, Barta, Jiri, Baum, Julia K., Berry, Allison, Bhatnagar, Ashish, Bhatnagar, Monica, Biddle, Jennifer F., Bittner, Lucie, Boldgiv, Bazartseren, Bottos, Eric, Boyer, Donal M., Braun, Josephine, Brazelton, William, Brearley, Francis Q., Campbell, Alexandra H., Caporaso, J. Gregory, Cardona, Cesar, Carroll, JoLynn, Cary, S. Craig, Casper, Brenda B., Charles, Trevor C., Chu, Haiyan, Claar, Danielle C., Clark, Robert G., Clayton, Jonathan B., Clemente, Jose C., Cochran, Alyssa, Coleman, Maureen L., Collins, Gavin, Colwell, Rita R., Contreras, Monica, Crary, Benjamin B., Creer, Simon, Cristol, Daniel A., Crump, Byron C., Cui, Duoying, Daly, Sarah E., Davalos, Liliana, Dawson, Russell D., Defazio, Jennifer, Delsuc, Frederic, Dionisi, Hebe M., Dominguez-Bello, Maria Gloria, Dowell, Robin, Dubinsky, Eric A., Dunn, Peter O., Ercolini, Danilo, Espinoza, Robert E., Ezenwa, Vanessa, Fenner, Nathalie, Findlay, Helen S., Fleming, Irma D., Fogliano, Vincenzo, Forsman, Anna, Freeman, Chris, Friedman, Elliot S., Galindo, Giancarlo, Garcia, Liza, Garcia-Amado, Maria Alexandra, Garshelis, David, Gasser, Robin B., Gerdts, Gunnar, Gibson, Molly K., Gifford, Isaac, Gill, Ryan T., Giray, Tugrul, Gittel, Antje, Golyshin, Peter, Gong, Donglai, Grossart, Hans-Peter, Guyton, Kristina, Haig, Sarah-Jane, Hale, Vanessa, Hall, Ross Stephen, Hallam, Steven J., Handley, Kim M., Hasan, Nur A., Haydon, Shane R., Hickman, Jonathan E., Hidalgo, Glida, Hofmockel, Kirsten S., Hooker, Jeff, Hulth, Stefan, Hultman, Jenni, Hyde, Embriette, Ibanez-Alamo, Juan Diego, Jastrow, Julie D., Jex, Aaron R., Johnson, L. Scott, Johnston, Eric R., Joseph, Stephen, Jurburg, Stephanie D., Jurelevicius, Diogo, Karlsson, Anders, Karlsson, Roger, Kauppinen, Seth, Kellogg, Colleen T. E., Kennedy, Suzanne J., Kerkhof, Lee J., King, Gary M., Kling, George W., Koehler, Anson V., Krezalek, Monika, Kueneman, Jordan, Lamendella, Regina, Landon, Emily M., Lane-deGraaf, Kelly, LaRoche, Julie, Larsen, Peter, Laverock, Bonnie, Lax, Simon, Lentino, Miguel, Levin, Iris I., Liancourt, Pierre, Liang, Wenju, Linz, Alexandra M., Lipson, David A., Liu, Yongqin, Lladser, Manuel E., Lozada, Mariana, Spirito, Catherine M., MacCormack, Walter P., MacRae-Crerar, Aurora, Magris, Magda, Martin-Platero, Antonio M., Martin-Vivaldi, Manuel, Martinez, L. Margarita, Martinez-Bueno, Manuel, Marzinelli, Ezequiel M., Mason, Olivia U., Mayer, Gregory D., McDevitt-Irwin, Jamie M., McDonald, James E., McGuire, Krista L., McMahon, Katherine D., McMinds, Ryan, Medina, Monica, Mendelson, Joseph R., Metcalf, Jessica L., Meyer, Folker, Michelangeli, Fabian, Miller, Kim, Mills, David A., Minich, Jeremiah, Mocali, Stefano, Moitinho-Silva, Lucas, Moore, Anni, Morgan-Kiss, Rachael M., Munroe, Paul, Myrold, David, Neufeld, Josh D., Ni, Yingying, Nicol, Graeme W., Nielsen, Shaun, Nissimov, Jozef I., Niu, Kefeng, Nolan, Matthew J., Noyce, Karen, OBrien, Sarah L., Okamoto, Noriko, Orlando, Ludovic, Castellano, Yadira Ortiz, Osuolale, Olayinka, Oswald, Wyatt, Parnell, Jacob, Peralta-Sanchez, Juan M., Petraitis, Peter, Pfister, Catherine, Pilon-Smits, Elizabeth, Piombino, Paola, Pointing, Stephen B., Pollock, F. Joseph, Potter, Caitlin, Prithiviraj, Bharath, Quince, Christopher, Rani, Asha, Ranjan, Ravi, Rao, Subramanya, Rees, Andrew P., Richardson, Miles, Riebesell, Ulf, Robinson, Carol, Rockne, Karl J., Rodriguezl, Selena Marie, Rohwer, Forest, Roundstone, Wayne, Safran, Rebecca J., Sangwan, Naseer, Sanz, Virginia, Schrenk, Matthew, Schrenzel, Mark D., Scott, Nicole M., Seger, Rita L., Seguin-Orlando, Andaine, Seldin, Lucy, Seyler, Lauren M., Shakhsheer, Baddr, Sheets, Gabriela M., Shen, Congcong, Shi, Yu, Shin, Hakdong, Shogan, Benjamin D., Shutler, Dave, Siegel, Jeffrey, Simmons, Steve, Sjoling, Sara, Smith, Daniel P., Soler, Juan J., Sperling, Martin, Steinberg, Peter D., Stephens, Brent, Stevens, Melita A., Taghavi, Safiyh, Tai, Vera, Tait, Karen, Tan, Chia L., Tas, Neslihan, Taylor, D. Lee, Thomas, Torsten, Timling, Ina, Turner, Benjamin L., Urich, Tim, Ursell, Luke K., van der Lelie, Daniel, Van Treuren, William, van Zwieten, Lukas, Vargas-Robles, Daniela, Thurber, Rebecca Vega, Vitaglione, Paola, Walker, Donald A., Walters, William A., Wang, Shi, Wang, Tao, Weaver, Tom, Webster, Nicole S., Wehrle, Beck, Weisenhorn, Pamela, Weiss, Sophie, Werner, Jeffrey J., West, Kristin, Whitehead, Andrew, Whitehead, Susan R., Whittingham, Linda A., Willerslev, Eske, Williams, Allison E., Wood, Stephen A., Woodhams, Douglas C., Yang, Yeqin, Zaneveld, Jesse, Zarraonaindia, Iratxe, Zhang, Qikun, and Zhao, Hongxia

Subjects
Biological diversity -- Observations -- Environmental aspects, Microbial colonies -- Environmental aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Our growing awareness of the microbial worlds importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earths microbial diversity., Author(s): Luke R. Thompson [1, 2, 3]; Jon G. Sanders [1]; Daniel McDonald [1]; Amnon Amir [1]; Joshua Ladau [4]; Kenneth J. Locey [5]; Robert J. Prill [6]; Anupriya Tripathi [...]

Published
2017
Full Text
View/download PDF

44. New Fitness 'Poop Pill' Promises Olympic-Level Results

Author

Scott, Nicole

Subjects
Dietary supplements -- Health aspects, Probiotics -- Health aspects, Science and technology, Nella (Dietary supplement) -- Health aspects
Abstract

There's a new product supposedly meant to aid in fitness: the Nella probiotic supplement. Probiotic supplements are not anything new to the market, but this one has a unique angle: [...]

Published
2022

46. Religious Land Wars.

Author

Scott, Nicole

Subjects
*RELIGIOUS wars, *RELIGION & politics
Published
2024

Catalog

Books, media, physical & digital resources
See catalog results