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Introduction Thoracic outlet syndrome (TOS) may lead to vascular complication and represents the minority of TOS case in adults. However in the pediatric population TOS vascular complications are morefrequent. Management is commonly described in adult populations, but in children and teenagersdiagnosis and treatment is not as well defined and presents different challenges than in adults. We describe three cases of vascular TOS in a pediatric population and review of the literature.Case Reports The first patient is a 14-year-old girl who was a competitive swimmer presented with left arm pain and swelling for several months worse the last 4 weeks. Venogram1 revealed complete occlusion of the left subclavian and axillary veins and following a course of lytic therapy a 50%axillary vein stenosis with complete occlusion with left arm abduction was noted2. She underwent left first rib resection and resumed competitive swimming. Follow up venous duplexshowed no venous compression with the arm adducted and with full abduction. Download : Download high-res image (315KB) Download : Download full-size image Figure 1. Download : Download high-res image (265KB) Download : Download full-size image Figure 2. Download : Download high-res image (287KB) Download : Download full-size image Figure 3. Download : Download high-res image (244KB) Download : Download full-size image Figure 4. Download : Download high-res image (258KB) Download : Download full-size image Figure 5. Download : Download high-res image (453KB) Download : Download full-size image Figure 6. The second patient is a 13-year-old female who was also a competitive swimmer but who coincidentally had mild scoliosis3. She presented after a 2 day history of left arm swelling. Venogram revealed left subclavian and axillary vein thrombosis and she also underwent a course of lytic therapy. Post-therapy imaging showed an occlusion of the left axillary vein with abduction similar to the first patient4 and so she also underwent left first rib resection. Follow up venous duplex showed no venous compression. The third patient is a 16-year-old male who had been weight training presented with sudden onset of left arm pain 1 week prior to admission. Arteriogram revealed occluded left axillary artery5. Following combined lytic therapy and open left brachial artery thrombectomy repeat arteriogram revealed a patent left axillary artery6 and complete occlusion with left arm abduction. He underwent left first rib resection. At 2 months of follow up he was asymptomatic with normal axillary duplex with the arm adducted and with abduction. Discussion Vascular complications of TOS in the pediatric population can be managed in a similar fashionas adults. Return to premorbid activities can be expected. Pediatric patients can present some challenges with timely diagnosis and treatment.

Endovascular repair has become the most frequent approach in the management of the ruptured infra-renal abdominal aorta aneurysm. When managing the ruptured patient with a significant retroperitoneal hematoma, abdominal compartment syndrome is often a consideration. Duodenal obstruction from the hematoma is rare and not typically a consideration. In the case of our patient, the intra-abdominal pressures were successfully managed conservatively. The large retroperitoneal hematoma, however, encased and obstructed the duodenum ultimately requiring a gastrojejunostomy. Similar rare cases of duodenal obstruction have been reported after open aortic repairs. We have not identified other cases in the literature of duodenal obstruction after endovascular management of a ruptured abdominal aorta aneurysm. We want to raise awareness to the possibility. In our opinion, conservative management would still be the preferred course of action, even if surgical management was ultimately required for the duodenal obstruction, as it reduces the initial insult in the patient with the aneurysmal rupture.

We report here the complete genome sequence of the facultative predatory bacterium Ensifer adhaerens strain Casida A. The genome was assembled into three circular contigs, with a main chromosome as well as two large secondary replicons, that totaled 7,267,502 bp with 6,641 predicted open reading frames.

We report here the complete genome sequence of the facultative predatory bacterium Ensifer adhaerens strain Casida A. The genome was assembled into three circular contigs, with a main chromosome as well as two large secondary replicons, that totaled 7,267,502 bp with 6,641 predicted open reading frames.

Recent combat casualties have stimulated a reassessment of the principles of management of high-risk extremity injuries with a normal vascular examination. Rapid evacuations have presented numerous U.S. soldiers to our service for evaluation in the early postinjury period. The objective of this single-institution report is to analyze the application of liberal arteriography in the delayed evaluation of modern wartime extremity injuries. Data from consecutive wartime evacuees evaluated for extremity injuries between March 2002 and November 2004 were prospectively entered into a database and retrospectively reviewed. Analysis was focused on arteriography and its role in our current diagnostic and therapeutic approach. Information including injury sites and mechanisms, associated trauma, battlefield repairs performed, arteriography technique, complications, findings, and need for further intervention were reviewed. Indications for imaging in this high-risk group included proximity to vascular structures, abnormal or equivocal physical examination, adjunctive operative planning, and evaluation of battlefield repair. Ninety-nine of 179 patients (55%) with extremity injuries underwent arteriography, with 142 total limbs studied. The majority of them were wounded by explosive devices (82%) or high-velocity rifle munitions (14%). Abnormalities were found in 75 of 142 (52.8%) imaged limbs in 46 of the 99 (46.5%) patients. Twenty-four of these patients (52.2%) required additional operative intervention. Occult vascular injury findings were associated with bony fracture in 68% and nerve injury in 16%. Median delay between injury and stateside evaluation was 6 days. Two thirds of these soldiers presented with a normal physical examination result. There were no access site complications or incidents of contrast-induced acute renal failure. The liberal application of arteriography is a low-risk method to provide high-yield data in the delayed vascular evaluation of extremities injured from modern military munitions. Physical examination findings remain the most useful indicator, but a normal examination can be misleading and should not guide the decision for invasive imaging. Lesions are found and require further intervention at a higher rate than expected from the typical civilian trauma experience.

Amaurosis fugax (AF), Hollenhorst plaques, central retinal artery occlusion (CRAO), and nonspecific visual symptoms are all reasons for patient referral for carotid artery evaluation. This study reviews the management of patients with visual signs or symptoms based on their clinical presentation, carotid duplex results, follow-up data, and outcome. We performed a retrospective review of all patients presenting to the Vascular Surgery Clinic between June 1996 and December 2001 for carotid duplex scanning because of the indication of a visual disturbance. A total of 3560 carotid duplex examinations were performed during the study period; 98 were performed for a visual complaint or finding. A total of 11.1% of group 1 (Hollenhorst plaques), 22.2% in group 2 (CRAO), 45% in group 3 (AF), and 9.8% in group 4 (nonspecific visual symptoms) had significant carotid disease and underwent carotid endarterectomy. No patient who underwent screening carotid duplex and did not have surgically correctable disease developed significant carotid disease or symptoms from carotid disease during the study period. Hollenhorst plaques, CRAO, and nonspecific visual complaints are a poor predictor of significant carotid stenosis, while AF had a significantly higher rate of surgically correctable carotid stenosis. Patients with visual signs or symptoms need an initial screening carotid duplex examination. If this does not show surgically correctable disease, patients do not need to return for further examinations unless another indication arises.

Background Patients with peripheral vascular disease have been excluded from initial studies of percutaneous suture-mediated closure devices (SMCD) despite representing a significant proportion of those requiring endovascular intervention. We sought to determine whether these devices could be safely used in patients with peripheral vascular disease. Methods Patients were stratified into two groups and five subgroups on the basis of indication for arteriography, and they were prospectively randomized at the end of the procedure to receive either the SMCD or manual compression. Ankle-brachial index was determined and duplex ultrasound scanning of the accessed femoral artery was performed, before and after the procedure. Ultrasound data included peak systolic velocity, minimum intraluminal vessel diameter, and presence or absence of calcified plaque. Time to hemostasis, ambulation, and discharge were recorded, and major or minor complications were noted. Results Of 102 patients included in the study, 52 patients were randomized to receive the SMCD. There was no difference in ankle-brachial index, minimum intraluminal vessel diameter, or peak systolic velocity in the accessed vessel after closure with SMCD or manual compression. Time to hemostasis, ambulation, and discharge was significantly less in the SMCD group ( P = .001). Presence of calcified plaque was not associated with complications ( P = .146). In the SMCD group, hemostasis was achieved with 49 of 52 devices (94.2%). There were six complications (5.9%), two of which were major and required operative intervention. All complications were hemorrhagic and not occlusive. There was no difference in overall complication rate between SMCD (7.7%) and manual compression (4.0%) groups ( P = .678). No infection was noted in any of the 102 patients. Conclusions Suture-mediated percutaneous arterial closure can be safely performed in patients with peripheral vascular disease, even in the presence of calcified plaque. This closure technique enables shorter time to hemostasis, ambulation, and hospital discharge. There are observed differences in minor, but not major, complication rates for MC versus percutaneous arterial closure in patients with peripheral vascular disease, but these differences did not achieve statistical significance in this small series.

A young, otherwise healthy man had chronic cough of 16 months’ duration. Evaluation revealed an aberrant right subclavian artery. Kommerell’s diverticulum without aneurysmal degeneration was present. Imaging studies showed compression of the esophagus but not the trachea. Results of methacholine challenge test were negative for evidence of reactive airway disease, but suggested mild variable intrathoracic obstruction. While aberrant right subclavian artery syndrome most commonly involves dysphagia, our patient’s only symptom was cough. Right subclavian artery to right common carotid artery transposition was performed, with oversewing of the subclavian artery stump to the left of the esophagus through a right supraclavicular incision. This treatment was curative, with complete resolution of symptoms.

The field of peripheral vascular disease management is evolving. As such, vascular surgeons can no longer be complacent and expect to be included in the rapidly expanding practice of endovascular intervention. If not engaged, vascular surgeons risk losing not only the patients who have largely driven this evolution but also their role as leaders in the management of vascular disease. Therefore vascular surgeons and vascular surgical training programs find themselves in an awkward and sometimes confrontational circumstance attempting to gain experience and training in catheter-based procedures. Individual societies, both surgical and nonsurgical, have put forth competence standards for catheter-based procedures. However these standards are not always consistent and the definition of competence is often a heated debate. In addition, combining the acquisition of endovascular skills with the multitude of available endovascular training experiences, didactic and “hands-on,” is not well coordinated. The objectives of this review are to summarize the literature as it relates to catheter-based endovascular competence, including publications from nonsurgical catheter-based specialties, and to place the acquisition of basic endovascular skills in context with the available endovascular courses in a stepwise strategy. A final objective is to provide a literature-based resource that outlines specific phases in the development of interventional vascular surgeons and training programs as they advance into the arena of catheter-based endovascular therapies.

We report the endovascular management of a patient with a type B aortic dissection complicated by renal ischemia and resultant severe hypertension. A 69-year-old male presented with acute type B aortic dissection with proximal extension complicated by severe renovascular hypertension secondary to left renal ischemia. Endovascular management consisted of imaging with intravascular ultrasound and left renal artery stenting with balloon-expandable stents. His hypertension subsequently resolved and he was discharged on his baseline two-drug regimen. Management of the ischemic complications of type B aortic dissections may be primarily approached using endovascular methods in stable patients, with open surgery reserved for those patients refractory to these methods. Patients with evidence of decreased renal perfusion represent a select group with an increased risk of associated morbidity and mortality and should therefore be aggressively managed. Accurate information and assessment of anatomy can be obtained with intravascular ultrasound and is therefore an important adjunct to the armamentarium of endovascular specialists managing complications of aortic dissection.

Background: The operative management of inflammatory abdominal aortic aneurysms has evolved based on a concept of minimal dissection and the morbidity associated with open repair of inflammatory aneurysms has decreased. Despite such progress, the technical challenges associated with open repair of inflammatory aneurysms are formidable, and an endovascular approach is an appealing alternative that extends the concept of minimal dissection. Objective: The objective of this report is to provide a literature-based statement on the endovascular repair of inflammatory abdominal aortic aneurysms concentrating on four main areas: feasibility of placement, efficacy of treatment, associated morbidity and mortality, and the response of perianeurysmal fibrosis and inflammation. Results: The published experience with endovascular repair of inflammatory abdominal aortic aneurysms is limited to two series of patients and fewer than 10 case reports. From this it appears that the endovascular repair of inflammatory abdominal aortic aneurysms is feasible and proceeds in a manner similar to the endovascular repair of degenerative aneurysms. Two aspects of endovascular repair influenced by the unique presentation of inflammatory aneurysms are the measurement of attachment site diameters and the flexibility of iliac arteries. Endovascular repair of inflammatory aneurysms is effective in preventing rupture and reducing perioperative morbidity. The response of perianeurysmal fibrosis to endovascular repair is varied and does not appear to be related to endograft type or endoleak status. Conclusions: Preliminary experience with endovascular repair of inflammatory abdominal aortic aneurysms suggests that this technique is feasible, safe, and effective. The varied response of perianeurysmal inflammation to endovascular repair is not dissimilar to clinical experience with open inflammatory aneurysm repair and is influenced by yet undefined factors.

The association of iliac artery aneurysms with a congenital pelvic kidney is extremely rare. Although multiple techniques are well described for renal preservation with renal ectopia in the setting of aortic reconstruction, few reports exist describing techniques for renal preservation in the setting of bilateral iliac artery aneurysms. A case is presented of a middle-aged man with a 6-cm right common iliac artery aneurysm and a 3-cm left common iliac artery aneurysm and a right pelvic kidney. A double-proximal-clamp technique and temporary shunting to the pelvic kidney were used during the aneurysm repair. The technical aspects of this procedure are presented as well as a brief discussion of the various options for renal preservation with renal ectopia when repairing complex aneurysmal disease.

Purpose: The efficacy of solvent—detergent-treated fibrin sealant (human [FSH]) for controlling anastomotic bleeding from expanded polytetrafluoroethylene (ePTFE) patch angioplasty during carotid endarterectomy was evaluated, and FSH was compared with thrombin-soaked gelatin sponge (Gelfoam; TSG). Methods: The study was of a randomized, open-label, single-site, single-treatment, parallel design that took place in a referral center with hospitalized patients. Forty-seven adult patients (33 men, 14 women) underwent elective carotid endarterectomy. Patients were randomized to receive either FSH (N = 24) or TSG (N = 23). FSH was obtained as an investigational new drug. FSH was applied as a liquid by means of a dual-syringe technique. Heparin anticoagulation, patch thickness, and suture type were standardized. Two different needle sizes were used (CV-6, PT-13: N=21 [FSH: N=10, TSG: N=11]; CV-6, PT-9: N=26 [FSH: N=14, TSG: N=13]). The FSH or TSG was applied to the ePTFE patch, and then blood flow was restored through the carotid artery. Degree of anticoagulation was assessed by anti-factor Xa activity. The time from restoration of carotid blood flow until achieving hemostasis was recorded. The blood loss from patch suture hole bleeding was measured. Completion intraoperative duplex ultrasound scanning was performed in all cases. Heparin was reversed with protamine sulfate. The primary end point was successful hemostasis within 15 minutes of restoration of carotid blood flow. The secondary end points were the amount of blood loss caused by suture line bleeding and the time to achieve hemostasis. Results: There was no difference in the number of patients with complete hemostasis at 15 minutes (TSG, 13 of 23; FSH, 12 of 24; P = .77). The measured blood loss was 99.0 ± 119.9 (SD) mL for TSG, and 105.0 ± 107.9 mL for FSH ( P = .86). The time to hemostasis was the same for both groups (TSG, 16.5 ± 16.5 minutes; FSH, 16.6 ± 14.2 minutes; P = .97). Within both treatment groups, the use of larger needles (PT-13) was associated with greater blood loss (FSH, 169.7 ± 124.2 mL; TSG, 172.7 ± 151.5 mL) than was the use of smaller needles (PT-9; FSH, 58.8 ± 66.3 mL; TSG, 34.1 ± 25.6 mL; P = .036, P = .001, respectively). There were no postoperative strokes or bleeding complications in either group. No abnormalities were shown in either group by means of completion carotid duplex ultrasound scanning. Conclusion: FSH was equivalent, but not superior to, TSG in achieving hemostasis during carotid endarterectomy performed with ePTFE patch angioplasty. Adhesion properties of FSH to ePTFE are possibly different than those to native tissue and warrant additional investigation. (J Vasc Surg 1999;30:461-7.)

Percutaneous transluminal angioplasty for atherosclerotic ostial lesions of the renal arteries has resulted in high restenosis rates. Recent reports of angioplasty with intravascular stenting show improved results over angioplasty alone. The purpose of this study is to review the results of primary stenting of ostial renal artery stenosis at our institution. Twenty one patients (11 men, 10 women, age 63 +/- 11 years), with atherosclerotic renal artery ostial stenosis in association with hypertension or renal insufficiency underwent renal angioplasty with primary stenting during a 2-year period. Medical records were reviewed for indications, technical success, complications, restenosis, response of hypertension and response of renal insufficiency. A technical success was defined as a normal postprocedure arteriogram with no residual stenosis and no residual gradient. Restenosis was defined asor =60% diameter reduction identified by arteriography, or duplex scan demonstrating a renal artery to aortic ratio ofor =3.5. Thirty-three stents were placed in 25 arteries with four patients having bilateral procedures. All patients were hypertensive. Nine patients (43%) had chronic renal insufficiency (creatinineor =1.5 mg/dl). One patient was on hemodialysis. The immediate technical success rate was 95%. Six complications occurred in four patients (two pseudoaneurysms, two dissections requiring additional stents, renal failure, and atheroembolization). Mean arterial blood pressure improved from 117 +/- 13.4 to 103 +/- 12.8 mmHg (p = 0.002) after stenting. Serum creatinine levels decreased from 1.48 +/- 0.57 to 1.31 +/- 0.41 (p = 0.07). Eight patients developed restenosis. The mean follow up was 13 +/- 7 months. Life table analysis showed a cumulative restenosis rate of 65 +/- 18% at 24 months. We advise caution in the application of renal stenting for the treatment of ostial lesions, particularly in patients for whom standard surgical revascularization options are available.

The purpose of this study is to evaluate the results of color-flow duplex ultrasound (CFD) soon after carotid endarterectomy (CEA) to determine the incidence of residual abnormalities and their effect on subsequent outcome and management.We reviewed 318 consecutive CEAs performed over a 48 month-period. Of these, 206 were followed up with CFD, 195 prior to discharge and 11 at first follow-up (within 9 weeks). Patients (43) followed up with only oculoplethysmography (OPG) or those with no OPG or CFD (69) were excluded from the study. All CEAs were performed under general anesthesia with routine shunting and patch angioplasty.Twelve of the 206 studies (5.8%) were abnormal. Two patients with an abnormal CFD sustained perioperative stroke, both of whom had distal intimal lesions of60% diameter stenosis by velocity criteria. Four patients had60% stenosis and were reoperated upon to correct technical errors. The remaining 6 patients are asymptomatic. Four had residual lesions of60% stenosis, three of which have returned to normal on subsequent CFD. Two residual lesions had60% stenosis; one returned to normal by CFD and the other remains abnormal at 10 months. In the group of 192 normal postoperative CFD studies, there were no strokes, deaths, or redo procedures (0%, 95% confidence interval 0% to 1.54%) compared with a combined 50% rate (6 of 12) of either stroke (2 of 12) or redo procedure (4 of 12) when the postoperative CFD was abnormal (95% confidence interval 22.3% to 77.7%, P0.0001). During the study period the CEA stroke rate was 0.9% (3 of 318), with a combined stroke-mortality rate of 1.3% (4 of 318).Early postoperative CFD identified residual abnormalities in 5.8% of carotid endarterectomies despite a low overall stroke mortality rate. One half of these abnormalities resulted in stroke or required operative correction. Colorflow duplex ultrasound is useful in identifying residual abnormalities following CEA and should be considered for intraoperative use.

Although hirulog, a specific, direct inhibitor of thrombin, can prevent thrombosis in unstable angina and angioplasty without inducing excessive bleeding, it has not been used in a surgical setting. In the present study, the antithrombotic activity of hirulog was assessed in rats undergoing carotid endarterectomy. Three groups of anesthetized male Sprague-Dawley rats received either intravenous heparin (10 U/kg bolus followed by 90 U/kg/hr, n = 4), high-dose hirulog (0.8 mg/kg bolus followed by 2.2 mg/kg/hr, n = 7), or saline (n = 6) before endarterectomy and until termination of the protocol 30 min later. Platelet deposition, as measured by scanning electron microscopy, in rats receiving this high dose of hirulog was reduced by 63% (+/- 14%, SE) compared to controls (P = 0.004) and by 36% (+/- 16%) in heparinized rats (P - 0.07). Both groups had prolonged postsurgical bleeding. Infusion of hirulog at a lower dose (0.4 mg/kg bolus followed by 1.0 mg/kg/hr, n = 8) was not associated with prolonged bleeding; however, platelet deposition was reduced by only 16% (+/- 27%, P = 0.30), although 125I-fibrin deposition was reduced by 64% (+/- 11%, P = 0.004). In the high-dose hirulog group, plasma hirulog levels, as determined with a quantitative thrombin time, were three times higher (95% CI: 1.5-4.5 times) than in the group receiving the lower hirulog dose [11.6 +/- 2.3 (SE) micrograms/ml vs 3.9 +/- 0.6 micrograms/ml; P = 0.0022]. However, the mean activated partial thromboplastin time with the higher dose was similar to that of the lower dose (110 +/- 4 vs 90 +/- 13 sec, P - 0.09). The antithrombotic activity of hirulog can be maximized by titrating the dose, monitoring plasma drug levels, and possibly administering the drug after surgery to avoid prolonged bleeding.

The in situ bypass procedure for lower extremity limb salvage requires a long continuous incision or multiple interrupted incisions over the greater saphenous vein to ligate the saphenous vein side branches. This can result in wound complications that frequently prolong hospital stay and threaten the graft. In an effort to reduce the incidence of wound complications, alternate methods of occluding the vein side branches have been used. One method is to deliver coils under angioscopic vision into the saphenous vein side branches. This report details a simplified technique that uses widely available catheter-based equipment to perform saphenous vein side branch occlusion under fluoroscopic guidance.

Endovascular techniques are often applied, but they have occasionally been reported in the treatment of popliteal vascular entrapment (PVE). A case of bilateral PVE is presented with an acute occlusion of the right popliteal artery. This was twice unsuccessfully treated with arterial recanalization and stenting at another Institution. The patient required an arterial reconstruction with his reversed saphenous vein, in addition to resection of the medial gastrocnemius muscle laterally inserted on his right limb. The left limb was treated with a simple myotomy. Recanalization and stenting is not recommended for PVE treatment.

Introduction Early recurrent carotid artery stenosis, defined as stenosis occurring within 2 years of carotid endarterectomy, occurs in 4% to 36% of patients. Management of asymptomatic early recurrent stenosis is controversial because of different outcomes in multiple natural history studies. Optimal follow-up post–carotid endarterectomy has not been defined. The purpose of this study was to determine the natural history of early recurrent stenosis and to define the optimal duplex surveillance strategy during follow-up. Methods Patients who underwent carotid endarterectomy between January 1995 and June 1998 at a single tertiary-care institution were reviewed retrospectively. Data were collected regarding degree of stenosis, closure technique, neurologic morbidity, mortality, and the intervals between postoperative duplex studies. These results were compared with accepted rates in the literature. Life-table analysis was done on restenosis-free survival. Discrete variables were tested for significance by chi-square analysis and Fisher’s exact test. A p value less than or equal to 0.05 was considered significant. Results Two hundred thirty-one carotid endarterectomies in 226 patients were evaluated. A total of 57 (24.6%) of 231 carotid endarterectomies had recurrent stenosis. These 57 sites were in 56 patients. Fifty-four (23.4%) of 231 sites had a stenosis of 16% to 59%. All of these lesions were asymptomatic and found within 1 year of carotid endarterectomy on duplex imaging. The 3 (1.3%) remaining sites had a restenosis of greater than 60%. Early recurrent stenosis occurred more frequently in women (women 28/80 [35%] vs. men 28/146 [19.2%]). High-grade stenosis occurred more often with primary (1/5 [20%]) than with patch (2/226 [0.8%]) closure and in patients less than 65 years of age.

In a patient with multiple trauma, blunt thoracic trauma with concomitant aortic disruption is often eminently lethal, ranking second to head injury as the most common cause of trauma-related deaths. Open surgical repair of the aortic lesion has morbidity and mortality rates that are among the highest in the field of cardiovascular surgery. Results with thoracic endovascular aortic repair for traumatic aortic disruption are promising. The facility requirements, technique, and early results of thoracic endovascular aortic repair for the treatment of this difficult aortic injury are presented.

Background: The optimal material for carotid patch angioplasty after endarterectomy remains uncertain. This study compares the early outcome and recurrent stenosis rates between saphenous vein (SV) and expanded polytetrafluoroethylene (ePTFE) carotid patch angioplasty. Methods: The results of 421 consecutive carotid endarterectomies performed over a 72-month period were reviewed. Postoperative complications and restenosis rates, defined as ≥ 60% narrowing measured by color flow duplex, were compared. Results: Patch angioplasty was performed with SV in 287 and with ePTFE in 110 cases. Patients who had undergone primary closure (n = 20) or whose form of closure was unknown (n = 4) were excluded. The mean age of patients and length of follow-up was similar between groups. Women were more likely to be patched with ePTFE than were men (36% versus 23%, P = 0.02). One death occurred in each group (0.3% SV, 0.9% ePTFE, P = 0.47), and four strokes occurred in each group (1.4% SV, 3.6% ePTFE, P = 0.22). Cervical hematomas requiring operative evacuation occurred in five SV closures and in three ePTFE closures (1.7% versus 2.7%, P = 0.69). Vein harvest site complications occurred in 6 patients (2%) who had undergone SV patch angioplasty. Recurrent stenosis occurred in 3 patients with SV closure and in 3 patients with ePTFE closure (1.0% versus 2.7%, P = 0.35). The 60-month restenosis rates by life table analysis were 2.6% ± 2.1% for SV and 10.7% ± 7.9% for ePTFE (P = 0.17). Conclusions : The incidence of postoperative complications is similar with SV or ePTFE patch angioplasty; however, vein harvest site complications are avoided with the use of ePTFE. Recurrent stenosis at 5 years occurs infrequently with either SV or ePTFE.

A healthy 29-year-old male suffered bilateral lower extremity fragment wounds resulting in a tense right calf shortly following a wound that required a four-compartment fasciotomy. During treatment of other injuries after medical evacuation he complained of increasing right calf pain. A peroneal pseudoaneurysm (PSA) with a concomitant arteriovenous fistula (AVF) was diagnosed. The distal one-third of the peroneal artery was not visualized, and the posterior tibial and anterior tibial arteries were normal. The patient underwent percutaneous coil embolization of the pseudoaneurysm. Completion arteriography demonstrated no evidence of the PSA and AVF. The patient's bruit and pain resolved.

A young, otherwise healthy man had chronic cough of 16 months' duration. Evaluation revealed an aberrant right subclavian artery. Kommerell's diverticulum without aneurysmal degeneration was present. Imaging studies showed compression of the esophagus but not the trachea. Results of methacholine challenge test were negative for evidence of reactive airway disease, but suggested mild variable intrathoracic obstruction. While aberrant right subclavian artery syndrome most commonly involves dysphagia, our patient's only symptom was cough. Right subclavian artery to right common carotid artery transposition was performed, with oversewing of the subclavian artery stump to the left of the esophagus through a right supraclavicular incision. This treatment was curative, with complete resolution of symptoms.

We studied the utility of electron beam computed tomography as a screening test for the cardiovascular risk of elective vascular surgery. In 45 patients undergoing principally carotid and aortic surgical procedures, coronary artery calcification was prevalent and severe, and related to the clinically predicted cardiovascular risk of the procedure. However, only the clinically predicted surgical risk, and not coronary artery calcification, was related to the incidence of perioperative cardiovascular complications.

Carotid body tumors (CBTs) have an unpredictable history with no correlation between histology and clinical behavior. Of reported cases since 1891, local and distant metastases appear in approximately 10% of cases and remain the hallmark of malignancy. Currently, there are not enough data to support a single treatment regimen for malignant CBTs. The reported case demonstrates some unanswered issues with regard to malignant CBTs to include lymph node dissection, the need for carotid resection, and the role of radiation therapy. A 46-year-old pathologist underwent a resection of a Shamblin I CBT, to include jugular lymph node sampling, without complication. There was lymph node involvement, and tumor cells were found on the margins of the pathologic specimen. Subsequent carotid resection with reversed interposition saphenous vein graft and modified neck dissection were performed again without complication. Follow-up at 4 years has been uneventful. Diagnosis of CBTs with the use of magnetic resonance angiography, magnetic resonance imaging, color flow duplex scanning, and the role of arteriography are reviewed. The current treatment options are discussed with reference to primary lymph node sampling, carotid resection, and neck dissection in malignant cases. This case demonstrates that the unpredictable nature of CBTs and their malignant potential warrant aggressive initial local treatment to include jugular lymph node sampling and complete tumor resection.

Chronic ergot toxicity is a rare cause of lower extremity ischemia. The cornerstone of therapy in ergot toxicity is to discontinue the use of caffeine, cigarettes, and all ergot-containing medications. Although multiple different therapies have been recommended for acute toxicity, no specific treatment is uniformly recommended in chronic toxicity. We present a case of long-term ergot use for migraine headaches in a woman who had severe chronic lower extremity claudication. This case demonstrates the unique features associated with the diagnosis and management of chronic ergot toxicity. We recommend a conservative approach consisting of observation, antiplatelet agents, and the discontinuance of ergots. If symptoms progress to rest pain or gangrene, surgical treatment should be considered. (J Vasc Surg 2000;31:1245-7.)

The finding of carotid stenosis contralateral to a carotid occlusion is becoming more frequent. While the neurologic outcomes in this patient population have been described, the rate of disease progression measured by duplex examination and the eventual need for carotid endarterectomy has not been described. In this study, a computerized database of carotid duplex examinations was reviewed and clinical data were obtained from clinic records. From 9124 studies 117 patients were identified. Thirty patients had previous carotid surgery on the patent side and were excluded. Of 87 patients 33 required carotid endarterectomy on the patent side. The rate of disease progression and/or the performance of a carotid endarterectomy by life-table analysis was 85.9% over 8 years. There were 10 neurologic events during the follow-up period. Patients with carotid stenosis and contralateral occlusion are at significant risk for disease progression. Follow-up should be more frequent and of longer duration in this patient population. A significant number of patients with carotid artery occlusion will require a carotid endarterectomy of the patent contralateral carotid.

The morbidity and cost of conventional angiography (CA) have focused recent efforts in cerebrovascular imaging upon the exclusive use of noninvasive techniques. Our purpose was to prospectively evaluate carotid magnetic resonance angiography (MRA) and to compare its accuracy with color-flow duplex (CFD). Fifty patients were prospectively evaluated with CA and MRA after clinical and CFD findings indicated the need for carotid angiography. CFD measurements of peak systolic velocity (PSV) and end-diastolic velocity (EDV) were made. MRA results were categorized as 0%-39%, 40%-59%, 60%-79%, or 80%-99% stenosis or occluded. Determination of percent carotid stenosis by CA was made as in the North American Symptomatic Carotid Endarterectomy Trial (NASCET). Using receiver operating characteristic (ROC) curves, the probability of correctly predicting a > or =60% stenosis using various CFD thresholds and MRA was assessed. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) in determining > or =60% stenosis were estimated. For MRA the sensitivity was 85% (95% Confidence Interval [CI] = 69%-94%), specificity 70% (CI = 56%-81 %), PPV 68% (CI = 53%-80%), and NPV 86% (CI = 72%-94%). For CFD the sensitivity was 89% (CI = 74%-96%), specificity 93% (CI = 82%-98%), PPV 89% (CI = 74%-96%), and NPV 93% (CI = 82%-98%). When MRA and CFD results were concordant (n = 64), the sensitivity was 100% (CI = 89%-100%), specificity 95% (CI = 81%-99%), PPV 94% (CI = 77%-99%), and the NPV was 100% (CI = 92%-100%). The area under the ROC curve for CFD was 95%, compared to 83% for MRA (p = 0.0005). We conclude that the low specificity of MRA precludes its use as the definitive imaging modality for carotid stenosis. The 93% specificity of CFD alone warrants its consideration as a definitive carotid imaging study. By ROC curve analysis, CFD offers superior accuracy to MRA. Our data support noninvasive preoperative carotid imaging for detecting a threshold stenosis of > or =60% whether CFD is used alone, or in combination with the selective use of MRA.

Ureteroiliac artery fistulas have been increasingly reported during the last 10 years and have been associated with pelvic irradiation, vascular pathology, ureteral stenting and prior pelvic surgery.' We report the endovascular management of this life threatening treatment dilemma. CASE REPORT

Purpose: Venous aneurysms have been reported to occur in most major veins. These aneurysms may be misdiagnosed as soft tissue masses or as inguinal or femoral hernias. Venous aneurysms of the deep system have been associated with deep venous thrombosis (DVT) and pulmonary embolism (PE). To more precisely characterize these lesions, we reviewed our experience with the disease. Methods: A retrospective analysis of our experience over 22 years was performed. The presentation and management of these lesions were reviewed and compared with the literature. Results: Thirty-nine venous aneurysms were reported in 30 patients. There were 14 men and 16 women. The patients' ages ranged from 3 to 75 years. Thirty aneurysms were located in the lower extremities, four in the upper extremity, and five in the internal jugular vein. Fifty-seven percent of lower extremity aneurysms occurred in the deep system. Patients' symptoms were a mass (75%) associated with pain (67%) and swelling (42%). Thromboembolism occurred in six patients, DVT in three, and PE in three. Eight of nine patients (89%) who had aneurysms of the superficial venous system had their condition misdiagnosed. Diagnosis was made by phlebography (60%), color flow duplex scanning (27%), continuous-wave Doppler scanning (10%), or magnetic resonance imaging (10%). The aneurysm size ranged from 1.7 to 6.0 cm. Management consisted of tangential excision in five (17%), total excision in 23 (77%), and observation in seven (6%). Conclusions: Venous aneurysms are unusual vascular malformations that occur equally between the sexes and are seen at any age. Most patients have a painful mass of the extremity, and diagnosis is achieved by radiologic examination. Superficial venous aneurysms of the inguinal region are often misdiagnosed. Thromboembolism is more common in aneurysms involving the deep venous system. Because of their potential morbidity, management should be surgical in the majority of cases. (J Vasc Surg 1997;26:845-52.)

Objective The approach to penetrating trauma of the head and neck has undergone significant evolution and offers unique challenges during wartime. Military munitions produce complex injury patterns that challenge conventional diagnosis and management. Mass casualties may not allow for routine exploration of all stable cervical blast injuries. The objective of this study was to review the delayed evaluation of combat-related penetrating neck trauma in patients after evacuation to the United States. Method From February 2003 through April 2005, a series of patients with military-associated penetrating cervical trauma were evacuated to a single institution, prospectively entered into a database, and retrospectively reviewed. Results Suspected vascular injury from penetrating neck trauma occurred in 63 patients. Injuries were to zone II in 33%, zone III in 33%, and zone I in 11%. The remaining injuries involved multiple zones, including the lower face or posterior neck. Explosive devices wounded 50 patients (79%), 13 (21%) had high-velocity gunshot wounds, and 19 (30%) had associated intracranial or cervical spine injury. Of the 39 patients (62%) who underwent emergent neck exploration in Iraq or Afghanistan, 21 had 24 injuries requiring ligation (18), vein interposition or primary repair (4), polytetrafluoroethylene (PTFE) graft interposition (1), or patch angioplasty (1). Injuries occurred to the carotid, vertebral, or innominate arteries, or the jugular vein. After evacuation to the United States, all patients underwent radiologic evaluation of the head and neck vasculature. Computed tomography angiography was performed in 45 patients (71%), including six zone II injuries without prior exploration. Forty (63%) underwent diagnostic arteriography that detected pseudoaneurysms (5) or occlusions (8) of the carotid and vertebral arteries. No occult venous injuries were noted. Delayed evaluation resulted in the detection of 12 additional occult injuries and one graft thrombosis in 11 patients. Management included observation (5), vein or PTFE graft repair (3), coil embolization (2), or ligation (1). Conclusions Penetrating multiple fragment injury to the head and neck is common during wartime. Computed tomography angiography is useful in the delayed evaluation of stable patients, but retained fragments produce suboptimal imaging in the zone of injury. Arteriography remains the imaging study of choice to evaluate for cervical vascular trauma, and its use should be liberalized for combat injuries. Stable injuries may not require immediate neck exploration; however, the high prevalence of occult injuries discovered in this review underscores the need for a complete re-evaluation upon return to the United States.

A 15-year-old male complained of easy fatigability, leg weakness, and pain on exertion with episodes of syncope while playing baseball. His past medical history was significant for aortic coarctation associated with a congenital bovine hypoplastic aortic arch. A recent arteriogram revealed innominate and left common carotid artery stenosis as well as recurrent coarctation. He had previously undergone three Dacron patch aortoplasties. At the age of 7, he underwent a fourth operation for recurrent coarctation and because of extensive scar tissue in the region of his prior procedures, a left subclavian artery-to-descending aortic bypass was performed. An endovascular repair to deal with the recent recurrence was performed because of prior surgical difficulties. Percutaneous balloon-expandable stents were placed in the aortic coarctation, innominate, and the left common carotid arteries. Postprocedure, ankle brachial indices were >1 and the patient remains asymptomatic after 1 year.