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212 results on '"Seeberger, Manfred D"'

3. Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death: A Substudy of the POISE-2 Trial

Author

Sessler, Daniel I., Meyhoff, Christian S., Zimmerman, Nicole M., Mao, Guangmei, Leslie, Kate, Vásquez, Skarlet M., Balaji, Packianathaswamy, Alvarez-Garcia, Jesús, Cavalcanti, Alexandre B., Parlow, Joel L., Rahate, Prashant V., Seeberger, Manfred D., Gossetti, Bruno, Walker, S. A., Premchand, Rajendra K., Dahl, Rikke M., Duceppe, Emmanuelle, Rodseth, Reitze, Botto, Fernando, and Devereaux, P. J.

Published
2018
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5. Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Author

Mazer, David C., Whitlock, Richard P., Fergusson, Dean A., Hall, Judith, Belley-Cote, Emilie, Connolly, Katherine, Khanykin, Boris, Gregory, Alexander J., de Médicis, Étienne, McGuinness, Shay, Royse, Alistair, Carrier, François M., Young, Paul J., Villar, Juan C., Grocott, Hilary P., Seeberger, Manfred D., Fremes, Stephen, Lellouche, François, Syed, Summer, Byrne, Kelly, Bagshaw, Sean M., Hwang, Nian C., Mehta, Chirag, Painter, Thomas W., Royse, Colin, Verma, Subodh, Hare, Gregory M.T., Cohen, Ashley, Thorpe, Kevin E., Jüni, Peter, and Shehata, Nadine

Published
2017
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12. Long-term prognostic value of the preoperative 12-lead electrocardiogram before major noncardiac surgery in coronary artery disease

Author

Jeger, Raban V., Probst, Cecilia, Arsenic, Ruza, Lippuner, Thomas, Pfisterer, Matthias E., Seeberger, Manfred D., and Filipovic, Miodrag

Subjects
Coronary heart disease -- Care and treatment, Coronary heart disease -- Patient outcomes, Electrocardiogram -- Research, Electrocardiography -- Research, Preoperative care -- Research, Cardiac patients -- Prognosis, Heart -- Surgery, Heart -- Patient outcomes, Health
Published
2006

23. Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death:A Substudy of the POISE-2 Trial

Author

Sessler, Daniel I, Meyhoff, Christian, Zimmerman, Nicole M, Mao, Guangmei, Leslie, Kate, Vásquez, Skarlet M, Balaji, Packianathaswamy, Alvarez-Garcia, Jesús, Cavalcanti, Alexandre B, Parlow, Joel L, Rahate, Prashant V, Seeberger, Manfred D, Gossetti, Bruno, Walker, S A, Premchand, Rajendra K, Dahl, Rikke M, Duceppe, Emmanuelle, Rodseth, Reitze, Botto, Fernando, Devereaux, P J, Sessler, Daniel I, Meyhoff, Christian, Zimmerman, Nicole M, Mao, Guangmei, Leslie, Kate, Vásquez, Skarlet M, Balaji, Packianathaswamy, Alvarez-Garcia, Jesús, Cavalcanti, Alexandre B, Parlow, Joel L, Rahate, Prashant V, Seeberger, Manfred D, Gossetti, Bruno, Walker, S A, Premchand, Rajendra K, Dahl, Rikke M, Duceppe, Emmanuelle, Rodseth, Reitze, Botto, Fernando, and Devereaux, P J

Abstract

BACKGROUND: The relative contributions of intraoperative and postoperative hypotension to perioperative morbidity remain unclear. We determined the association between hypotension and a composite of 30-day myocardial infarction and death over three periods: (1) intraoperative, (2) remaining day of surgery, and (3) during the initial four postoperative days.METHODS: This was a substudy of POISE-2, a 10,010-patient factorial-randomized trial of aspirin and clonidine for prevention of myocardial infarction. Clinically important hypotension was defined as systolic blood pressure less than 90 mmHg requiring treatment. Minutes of hypotension was the exposure variable intraoperatively and for the remaining day of surgery, whereas hypotension status was treated as binary variable for postoperative days 1 to 4. We estimated the average relative effect of hypotension across components of the composite using a distinct effect generalized estimating model, adjusting for hypotension during earlier periods.RESULTS: Among 9,765 patients, 42% experienced hypotension, 590 (6.0%) had an infarction, and 116 (1.2%) died within 30 days of surgery. Intraoperatively, the estimated average relative effect across myocardial infarction and mortality was 1.08 (98.3% CI, 1.03, 1.12; P < 0.001) per 10-min increase in hypotension duration. For the remaining day of surgery, the odds ratio was 1.03 (98.3% CI, 1.01, 1.05; P < 0.001) per 10-min increase in hypotension duration. The average relative effect odds ratio was 2.83 (98.3% CI, 1.26, 6.35; P = 0.002) in patients with hypotension during the subsequent four days of hospitalization.CONCLUSIONS: Clinically important hypotension-a potentially modifiable exposure-was significantly associated with a composite of myocardial infarction and death during each of three perioperative periods, even after adjustment for previous hypotension.

Published
2018

24. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery

Author

Mazer, C. David, primary, Whitlock, Richard P., additional, Fergusson, Dean A., additional, Belley-Cote, Emilie, additional, Connolly, Katherine, additional, Khanykin, Boris, additional, Gregory, Alexander J., additional, de Médicis, Étienne, additional, Carrier, François M., additional, McGuinness, Shay, additional, Young, Paul J., additional, Byrne, Kelly, additional, Villar, Juan C., additional, Royse, Alistair, additional, Grocott, Hilary P., additional, Seeberger, Manfred D., additional, Mehta, Chirag, additional, Lellouche, François, additional, Hare, Gregory M.T., additional, Painter, Thomas W., additional, Fremes, Stephen, additional, Syed, Summer, additional, Bagshaw, Sean M., additional, Hwang, Nian-Chih, additional, Royse, Colin, additional, Hall, Judith, additional, Dai, David, additional, Mistry, Nikhil, additional, Thorpe, Kevin, additional, Verma, Subodh, additional, Jüni, Peter, additional, and Shehata, Nadine, additional

Published
2018
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30. Assessing Left Ventricular Dimensions in Patients During Coronary Artery Bypass Surgery by Transoesophageal Echocardiography.

Author

Bolliger, Daniel, Poltera, Corsin, Cheung, Albert T., Couture, Pierre, Michaux, Isabelle, Poelaert, Jan, Preisman, Sergey, Skarvan, Karl, Buse, Giovanna Lurati, and Seeberger, Manfred D.

Subjects
CORONARY heart disease treatment, CORONARY artery bypass, ARTIFICIAL respiration, ANESTHESIA, ECHOCARDIOGRAPHY
Abstract

Copyright of Turkish Journal of Anesthesia & Reanimation is the property of Turkish Society of Anaesthesiology & Reanimation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017
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34. Response to Letters Regarding Article, “Randomized Comparison of Sevoflurane Versus Propofol to Reduce Perioperative Myocardial Ischemia in Patients Undergoing Noncardiac Surgery”

Author

Lurati Buse, Giovanna A.L., primary, Schumacher, Philippe, additional, Seeberger, Esther, additional, Studer, Wolfgang, additional, Schuman, Regina M., additional, Fassl, Jens, additional, Kasper, Jorge, additional, Filipovic, Miodrag, additional, Bolliger, Daniel, additional, and Seeberger, Manfred D., additional

Published
2013
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35. Reduced aspirin responsiveness as assessed by impedance aggregometry is not associated with adverse outcome after cardiac surgery in a small low-risk cohort.

Author

Bolliger, Daniel, Filipovic, Miodrag, Matt, Peter, Tanaka, Kenichi A., Gregor, Michael, Zenklusen, Urs, Seeberger, Manfred D., and Lurati Buse, Giovanna

Subjects
ASPIRIN, NONSTEROIDAL anti-inflammatory agents, CARDIAC surgery, UNCERTAINTY, REASONING
Abstract

Reduced aspirin responsiveness (i.e. persistent high platelet reactivity in platelet function testing) might be associated with increased risk of myocardial ischemia and cardiac mortality in patients with coronary disease. However, the impact in patients undergoing coronary artery bypass grafting (CABG) is unclear. The aim of this prospective cohort study was to evaluate the predictive value of reduced aspirin responsiveness on cardiac and thromboembolic events in patients undergoing elective isolated CABG surgery with aspirin intake until at least two days before surgery. We included 304 patients in this prospective single-center cohort study. Impedance platelet aggregometry (Multiplate®) was performed directly before and on the first day after surgery. Reduced aspirin responsiveness was defined as area under the curve in ASPItest (AUCASPI) ≥300 U. The primary outcome was a composite of all-cause mortality and/or major adverse cardiac or thromboembolic events within 1 year. Reduced aspirin responsiveness was found in 13 and 24% of patients pre and postoperatively, respectively. There was no difference in the outcomes between patients with normal and reduced aspirin responsiveness in the preoperative measurement (log-rank test,p = 0.540). Multivariate analysis including logistic EuroSCORE I and postoperative troponin T levels did not show any association of reduced aspirin responsiveness with adverse outcome (hazard ratio, 0.576; (95% CI 0.128–2.585;p = 0.471). Similarly, postoperative reduced aspirin responsiveness was not associated with adverse events. To conclude, reduced aspirin responsiveness as evaluated by Multiplate® platelet function analyzer was not associated with increased incidence of major adverse cardiac and thromboembolic events and mortality after CABG surgery. [ABSTRACT FROM PUBLISHER]

Published
2016
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40. Impact of the American College of Cardiology/American Heart Association guidelines for interpretability of continuous electrocardiography on the association of silent ischemia with troponin release after major noncardiac surgery

Author

Lurati Buse, Giovanna A., primary, Seeberger, Manfred D., additional, Schumann, Regina M., additional, Bürgler, David, additional, Schwab, Hildebrand S., additional, Bolliger, Daniel, additional, and Filipovic, Miodrag, additional

Published
2009
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42. Rivastigmine for the prevention of postoperative delirium in elderly patients undergoing elective cardiac surgery—A randomized controlled trial*

Author

Gamberini, Melanie, primary, Bolliger, Daniel, additional, Lurati Buse, Giovanna A., additional, Burkhart, Christoph S., additional, Grapow, Martin, additional, Gagneux, Alexa, additional, Filipovic, Miodrag, additional, Seeberger, Manfred D., additional, Pargger, Hans, additional, Siegemund, Martin, additional, Carrel, Thierry, additional, Seiler, Walter O., additional, Berres, Manfred, additional, Strebel, Stephan P., additional, Monsch, Andreas U., additional, and Steiner, Luzius A., additional

Published
2009
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