Search

First studies show that measures to contain the Covid-19 pandemic (travel restrictions, contact reduction through "social distancing", quarantine, lockdown) are associated with strong negative psychological effects such as increased anxiety symptoms, depression symptoms, stress and moderate to severe psychological strain (Wang et al., 2020). In order to prevent the negative psychological consequences of quarantine and contact reduction measures, low-threshold, costeffective prevention and intervention measures accessible to large population groups are necessary. One measure that meets these requirements is exercise. Caspersen, Powell, and Christenson (1985) define exercise as a planned, regularly performed physical activity with the aim of maintaining or positively influencing physical fitness. Numerous studies show preventive effects of exercise on the symptoms of mental illness triggered by Covid-19 measures. A meta-analysis by Mammen and Faulkner (2013) shows that physical acitivty reduces the probability of depression by 8 to 63 percent. Exercise also has a protective effect against anxiety symptoms and anxiety disorders (Schuch et al., 2019). Sporndly- Nees, Asenlof, and Lindberg (2017) have compared the sleep quality of persons with high and low total physical activity. High physcial activiy is associated with a 53% lower probability of insomnia. In order to be able to use the preventive effect of SpA in crisis situations such as the Covid-19 pandemic, it is first necessary to study the relationship between SpA and psychological variables during the pandemic. We would like to close this gap with our study in order to create a basis for the development of appropriate prevention and intervention measures.

Hintergrund und Stand (inter)nationaler Forschung: Sportliche Aktivität hat einen positiven Einfluss auf die Symptomatik von Menschen mit psychischen Erkrankungen [ref:1]. Die Bewegungsintervention ImPuls soll sie darin unterstützen, ihre Symptomatik zu verbessern und sportliche [zum vollständigen Text gelangen Sie über die oben angegebene URL]

This research question is a part of the ImPuls study. The study protocol of the ImPuls study is published at https://doi.org/10.1186/s12888-021-03541-3 and registered in the German Clinical Trial Register (ID: DRKS00024152, 05/02/2021).

These research question is a part of the ImPuls study. The study protocol of the ImPuls study is published at https://doi.org/10.1186/s12888-021-03541-3 and registered in the German Clinical Trial Register (ID: DRKS00024152, 05/02/2021). We know from literature that there are a lot of variables that may have an impact on the symptom severity in a transdiagnostic sample of different mental disorders. In the following section we will shortly present possible impact factors that are also assumed to be mechanisms of change within the pragmatic randomized controlled trial (RCT). Physical activity (PA) and PA-related health competence (PAHCO). There is a body of evidence assuming that PA that is planned, structured and repeated, with the primary aim to improve or maintain physical fitness (Caspersen et al., 1985) might represent a preventive factor as well as an effective treatment in patients suffering from mental disorders. In a recently published RCT, an exercise intervention was efficacious in improving global symptom severity in a transdiagnostic sample (Zeibig et al., 2021). The results indicate that the reduction of global symptom severity was predicted by an increase in the amount of PA (Zeibig et al., 2021). Furthermore, exercise-specific affect regulation as part of PAHCO (Schmid et al., 2020) seemed to underly treatment effects (Zeibig et al., under review). Repetitive negative thinking (RNT). RNT defined as “a mode of responding to distress that involves repetitively and passively focusing on symptoms of distress and the possible causes and consequences of these symptoms” (Nolen-Hoeksema et al., 2008) might be a transdiagnostic risk factor for severity of depression and anxiety (Spinhoven et al., 2018). Sleep quality. Sleep disturbance is a symptom of many axis I disorders, e.g. in posttraumatic stress disorder or depressive disorders. In fact, depressed patients who also suffer from insomnia report higher levels of symptom severity compared to depressed patients without insomnia (Sunderajan et al., 2010). Evidence that extends these results to patients with other psychiatric disorders indicate that impaired sleep quality is strongly associated with higher levels of psychiatric symptom severity, assessed by patients themselves and clinicians (Kallestad et al., 2012). Health-related quality of life (HRQoL). HRQoL describes the perceived physical and mental health of an individual over time and includes correlates of HRQoL as health risks, functional status and social support (Centers for Disease Control and Prevention, 2000). A general population survey revealed that depressive and anxiety disorders are associated with the poorest outcome of HRQoL (Saarni et al., 2007). Regarding symptom severity, HRQoL seems to be negatively correlated among depressive patients (Cao et al., 2013) and patients suffering from post-traumatic stress disorder (Nachar et al., 2013) as well as from insomnia (Kyle et al., 2010). Perceived stress. Stress is defined as situations “in which environmental demands, internal demands, or both, tax or exceed the adaptive resources of an individual, social system, or tissue system” (Monat & Lazarus, 1991). Acute stressful life events or chronic levels of stress are a risk factor for a broad range of mental disorders such as posttraumatic stress disorder, depression, insomnia and anxiety disorders (Basta et al., 2007; Smoller, 2016). At the same time, people suffering from mental disorders are more sensitive to stress and experience higher levels of stress than healthy people (Connor et al., 2007; Zorn et al., 2017). However, research regarding symptom severity in a clinical sample is still pending. Fear of the corona virus (FoC). During the Covid-19 pandemic, people were confronted with a new, fast-spreading virus that was associated with high mortality rates, lack of treatment methods and overstrained health systems (Meyerowitz-Katz & Merone, 2020; Wiersinga et al., 2020). This situation was associated with high FoC in the population (Luo et al., 2021) and first results suggest that FoC is positively associated with symptom severity in depression and anxiety disorders (Belen, 2021; Fink et al., 2021; Rogers et al., 2021). Emotional regulation (ER). ER is defined as the “extrinsic and intrinsic processes responsible for monitoring, evaluating, and modifying emotional reactions, especially their intensive and temporal features, to accomplish one’s goal” (Thompson, 1994). Deficits in ER may favor the development of depression (Berking et al., 2014) and among patients suffering from depression deficits are seen as one key factor in the maintenance of symptoms (Ehring et al., 2010). In turn, enhancing ER skills using specific interventions may reduce symptom severity in depressive patients (Radkovsky et al., 2014). Emotional intelligence (EI). EI is defined as „the ability to process your emotions and others’ emotions to guide your thinking and behavior” (Ahmed Okasha et al., 2022) and impaired EI is seen as one principal component in depressive disorders (Fisher et al., 2010). Thus, research implies that impaired self-perceived EI is correlated with symptom severity among depressive patients (Ahmed Okasha et al., 2022). Sociodemographic data. Among a representative adult German sample, the prevalence of common mental disorders (e.g. depression or anxiety disorders) is higher among females, except for substance use disorders (Klose & Jacobi, 2004). Furthermore, being single, separated, divorced or widowed as well as being unemployed is associated with an increased risk of any mental disorder. Regarding the prevalence of depressive or anxiety disorders, no age effects were found (Klose & Jacobi, 2004) and higher education seems to yield lower rates of mood disorders (Alonso et al., 2004). However, research regarding symptom severity in a clinical sample is still pending. To summarize we can say that there are various variables associated with symptom severity of different mental disorders. However, they are mainly investigated in disorder-specific samples which is not in line with growing evidence supporting transdiagnostic treatments in patients with mental disorders (Dalgleish et al., 2020). Thus, research regarding impact factors on global symptom severity in a transdiagnostic sample is necessary. These results could provide important information that could be used to create transdiagnostic therapy approaches focusing on those impact factors with the highest impact on global symptom severity.

Everyday people are confronted with the perception of stress caused by several problems and challenges. These so-called stressors reach from long lists of tasks at work over the car traffic at rush hour up to social conflicts at home. Furthermore, crises of world affairs such as the Covid-19 pandemic are additional stressors, associated with a high prevalence of stress among the general population (Salari et al., 2020). Stress is defined as situation “in which environmental demands, internal demands, or both, tax or exceed the adaptive resources of an individual, social system, or tissue system,” (Monat & Lazarus, 1991). Acute stressful life events or chronic levels of stress are a risk factor for a broad range of mental disorders such as posttraumatic stress disorder (PTSD), major depressive disorder (MDD), Insomnia and anxiety disorders (Basta et al., 2007; Smoller, 2016). At the same time, people suffering from mental disorders are more sensitive to stress and experience higher levels of stress than healthy people (Connor et al., 2007; Zorn et al., 2017). Therefore, these mental disorders are also called stress-related disorder (Smoller, 2016). Stress does not necessarily lead to the development of a mental disorder, but it is generally associated with a lower quality of life (QOL) (Chaudhury et al., 2018). QOL is defined as the “individuals' perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns” (WHOQOL, 1998, p. 1570). According to a systematic review the negative association between stress and QOL becomes even stronger if people also suffer from disorders such as sleep disorders, burnout or depression (Ribeiro et al., 2018). However, studies mainly compared stress and QOL from samples consisting of individuals with a specific mental disorder with healthy controls (Berghofer et al., 2020; Zorn et al., 2017). Although both constructs are shared relevant factors across all stress-related disorders, there is a gap in data from transdiagnostic analyses. One part of this study is therefore to fill this gap. Physical activity (PA), which is “any bodily movement produced by skeletal muscles that results in energy expenditure” (Caspersen et al., 1985, p. 128), has a contrary effect to stress on mental health in that it directly reduces the experience of stress but also elevates mood and increases QOL not only in healthy people but also in people suffering from mental disorders such as depression or anxiety disorder (Penedo & Dahn, 2005; White et al., 2017). The latter mechanism is attributed to the so-called stress-buffering hypothesis. According to this hypothesis, the increase, or a reduced decrease – compared to stronger decreases – in characteristics such as QOL is due to a reduction in the negative impact of stress (Gerber & Puhse, 2009). In one of the studies investigating the effect university students with more PA have been shown to be more satisfied in life and having higher positive affect than the group with lower levels of PA although they were confronted with the same academical stressors during this period (Wunsch et al., 2017). However, there is a lack of data on this hypothesis with regard to people suffering from mental disorders as – to our knowledge – it has only been tested on healthy people with provoked or naturally occurring stressors or people with physical diseases (Giessing et al., 2021; Klaperski & Fuchs, 2021; Schilling et al., 2020). Especially in terms of the underlying transdiagnostic mechanisms already mentioned, the idea of a stress buffer through PA does not seem to have been explored yet. Hence, this context gives rise to tow objectives for this study. In a first step we want to show that stress and QOL can be seen as underlying transdiagnostic factors in people with stress-related disorders. We expect higher levels of stress among the transdiagnostic sample and we also suspect that this group shows lower QOL due to the negative association of these two factors than the matched healthy sample. The second and also the main aim of this study is to shed light on the impact of PA on the association between stress and QOL in a transdiagnostic sample of people suffering from depression (mild, severe), insomnia, post-traumatic stress disorder and/or panic disorder (with or without agoraphobia).

Supplemental material, sj-pdf-1-jad-10.1177_10870547211017982 for The Efficacy of Physical Activity for Children with Attention Deficit Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials by Britta Seiffer, Martin Hautzinger, Rolf Ulrich and Sebastian Wolf in Journal of Attention Disorders

Additional file 1. TIDieR-Checklist.pdf (TIDieR Checklist).

Hintergrund: In Deutschland erhalten lediglich 10% aller Patienten mit psychischen Erkrankungen eine evidenzbasierte Behandlung [ref:1]. Die Wartezeiten auf einen Therapieplatz betragen im Durchschnitt ca. fünf Monate. Die Wirksamkeit ausdauerorientierter sportlicher Aktivität[zum vollständigen Text gelangen Sie über die oben angegebene URL], 19. Deutscher Kongress für Versorgungsforschung (DKVF)