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Your search keyword '"Semolin, Lívia Maria Souza"' showing total 4 results
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4 results on '"Semolin, Lívia Maria Souza"'

1. Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo

Author

Anai, Letícia Abrahão, Coleta, Flávia Eiras Dela, Munhoz, Thiago Demarchi, Nogueira, Andressa Francisca Silva, Semolin, Lívia Maria Souza, Vieira, Manuela Cristina, and Santana, Aureo Evangelista

Subjects
Lymphoma, Linfoma, Dog, CD45, Cão
Abstract

Lymphoma is the most common hematopoietic tumor in dogs and one of the malignant tumors with higher occurrence in this species. It is a great experimental model due to its resemblance with the non- Hodgkin lymphoma in humans. Considering the importance of the overall changes that result from to this kind of neoplastic tumor and those due to polichemotherapy this study aimed to evaluate the absolute leukon count and the total count of CD45+ cells in the blood of 25 dogs with lymphoma. Findings were crosschecked since diagnose and then once weekly during the first eight sessions of the Madison-Wisconsin chemotherapic protocol. Total granulocyte, lymphocyte and monocyte counts obtained from a conventional automatic counter and by flow cytometry were compared. Results did not reveal statistically significant changes between the two techniques. O linfoma é o tumor de tecido hematopoético mais comum nos cães e um dos tumores malignos de maior ocorrência nesta espécie. É um ótimo modelo experimental para estudo devido a sua semelhança com o linfoma não-Hodgkin em humanos. Considerando a importância das alterações decorrentes da evolução desta neoplasia e aquelas ocorridas com o emprego da poliquimioterapia, avaliou-se o leucograma absoluto e a contagem de células CD45+ pela citometria de fluxo, no sangue de 25 cães com linfoma. Foram avaliados no momento do diagnóstico, uma vez por semana, durante as primeiras oito sessões quimioterápicas do protocolo de Madison-Wisconsin, e cujas contagens obtidas em contador automático convencional e por intermédio da citometria de fluxo, foram comparadas. Os resultados obtidos não revelaram diferenças estatisticamente significativas entre as duas técnicas utilizadas.

Published
2013

2. Endoscopic approach for a laryngeal neoplasm in a dog

Author

Teixeira, Pedro Paulo Maia, primary, Souza, Erica Siqueira, additional, Jark, Paulo César, additional, Coutinho, Leandro Nassar, additional, Silva, Alanna do Socorro Lima da, additional, Guiduce, Marcos Vinicius Sicca, additional, Maria, Bruna Piva, additional, Silva, Paloma Espirito Santo, additional, Semolin, Lívia Maria Souza, additional, Silva, Marco Augusto Machado, additional, Vicente, Wilter Ricardo Russiano, additional, Tinucci-Costa, Mirela, additional, and Nardi, Andrigo Barboza De, additional

Published
2014
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3. Combination Chemotherapy with Firocoxib Induces Reduction of Regulatory T Cells in Dogs with Multicentric B Cell Lymphoma.

Author

Anai, Letícia Abrahão, Munhoz, Thiago Demarchi, Semolin, Lívia Maria Souza, Fonseca, Denise Morais da, Jark, Paulo César, Sueiro, Felipe Augusto Ruiz, Calazans, Sabryna Gouveia, Costa, Mirela Tinucci, and Santana, Aureo Evangelista

Subjects
*T cells, *COMBINATION drug therapy, *LYMPHOMAS, *DOGS, *THERAPEUTICS, *B cells
Abstract

The aim of this study was to quantify T cells (CD4+, CD8+ and Treg), in dogs with multicentric lymphoma treated with a conventional CHOP protocol or with one in which firocoxib was used instead of prednisone. Twenty-one dogs with lymphoma were divided into two treatment groups (G1=10 and G2=11): those that received the conventional CHOP protocol for 19 weeks (CHOP group) and those that received CHOP protocol with firocoxib instead of prednisone (CHOF group). Twelve clinically healthy dogs were used as control. The percentage of Treg cells were three times greater in animals with lymphoma than in the control group (P<0.05). During treatment, the reduction in Treg cells was slower in animals treated with firocoxib than in those that received prednisone. No significant difference (P>0.05) was observed in survival time between the two treatment protocols. It can be concluded that the use of firocoxib instead of prednisone in CHOP protocol can induce Treg cell remission in dogs with multicentric lymphoma without interfering with the survival time of these animals. [ABSTRACT FROM AUTHOR]

Published
2019
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4. Endoscopic approach for a laryngeal neoplasm in a dog.

Author

Teixeira, Pedro Paulo Maia, Souza, Erica Siqueira, Jark, Paulo César, Coutinho, Leandro Nassar, da Silva, Alanna do Socorro Lima, Guiduce, Marcos Vinicius Sicca, Maria, Bruna Piva, Silva, Paloma Espirito Santo, Semolin, Lívia Maria Souza, Silva, Marco Augusto Machado, Vicente, Wilter Ricardo Russiano, Tinucci-Costa, Mirela, and De Nardi, Andrigo Barboza

Subjects
*ENDOSCOPY, *LARYNGEAL cancer treatment, *VETERINARY therapeutics, *DOG diseases, *RADIOGRAPHY, *VETERINARY histopathology, *SURGICAL excision
Abstract

Laryngeal and tracheal tumors are rare in pets; some piece of information on their disease behavior, therapy and evolution are limited. Neoplasms in this area are a diagnostic challenge. In many cases, they can be biopsied and excised using endoscopic instruments, but there is no report of this in canines. The goal of this study is to report a successful case of a laryngeal neoplasm removal through endoscopy. A head and neck radiogram revealed a mass in the laryngeal lumen protruding into the trachea. The patient then underwent an endoscopy to confirm the radiographic diagnosis and to surgically remove the tumor. The histopathological diagnosis was poorly differentiated carcinoma. The most appropriate treatment for laryngeal tumors is the resection of the submucosa or a partial laryngectomy however, partial and total laryngectomies are associated with many postoperative complications. In contrast, the endoscopic approach allows for highly magnified visualization of the lesion in situ, which facilitates the surgical removal of the mass through videosurgery. With little manipulation of the affected area, the chances of postoperative complications are reduced, leading to a more rapid recovery. [ABSTRACT FROM AUTHOR]

Published
2015
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