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4. The effects of shift work on sleep quality, diet quality, and obesity-related factors: A male population study.

Author

Turan-Demirci, Busra, Isgin-Atici, Kubra, Sendur, Suleyman Nahit, Erbas, Tomris, and Buyuktuncer, Zehra

Subjects
SLEEP quality, DIETARY patterns, BODY composition, SHIFT systems, FOOD habits
Abstract

Recent studies suggest that shift working may trigger health issues through disrupted circadian rhythms and altered eating habits. This study aimed to examine the possible associations of shift work with sleep quality, diet quality and obesity-related parameters. This study was conducted with 150 males (75 shift and daytime workers) aged 24–50 years. Dietary intake was determined using the 24-hour recall method, and dietary quality was evaluated using the Healthy Eating Index-2010 (HEI-2010). Anthropometrical measurements and body composition were assessed. The Pittsburgh Sleep Quality Index was used to evaluate sleep quality. Fasting and postprandial glucose and insulin, and fasting lipid levels were analyzed. HOMA-IR was calculated, and blood pressure was measured. The total HEI-2010 score of shift workers (52.6 [45.4–58.8]) was lower than the daytime workers (55.9 [49.1–64.9]) (p = 0.016). Among individuals with good sleep quality, the total HEI-2010 score, seafood and plant proteins, fatty acids, and sodium scores were lower in shift workers compared to others (p < 0.05 for each). Non-obese shift workers had higher body weight, waist circumference, waist/hip ratio, VLDL-cholesterol, triglyceride, postprandial glucose, and insulin levels compared to daytime workers (p < 0.05 for each). This study demonstrates that shift working is associated with lower diet quality independent of sleep quality. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Contributors

Author

Abbott, David H., primary, Altieri, Paola, additional, Anagnostis, Panagiotis, additional, Antoniou-Tsigkos, Athanasios, additional, Armeni, Eleni, additional, Balen, Adam H., additional, Barber, Thomas M., additional, Benvenga, Salvatore, additional, Carmina, Enrico, additional, Cecchetti, Carolina, additional, Crisosto, Nicolás, additional, Di Bari, Flavia, additional, Diamanti-Kandarakis, Evanthia, additional, Dinicola, Simona, additional, Escobar-Morreale, Héctor F., additional, Fanelli, Flaminia, additional, Fighera, T.M., additional, Forte, Gianpiero, additional, Gambineri, Alessandra, additional, Georgescu, Carmen Emanuela, additional, Georgopoulos, Neoklis A., additional, Goulis, Dimitrios G., additional, Greinwald, Emily P., additional, Kahal, Hassan, additional, Kandaraki, Eleni, additional, Kyrou, Ioannis, additional, Lambrinoudaki, Irene, additional, Lecke, S.B., additional, Levine, Jon E., additional, Marchesan, L.B., additional, Markantes, Georgios K., additional, Mascarenhas, Mariano, additional, Mastorakos, George, additional, Memi, Eleni, additional, Moghetti, Paolo, additional, Monastra, Giovanni, additional, Oguz, Seda Hanife, additional, Pagotto, Uberto, additional, Papadimitriou, Kasiani, additional, Papalou, Olga, additional, Pastroma, Konstantina, additional, Pereira, Sofia S., additional, Pignatelli, Duarte, additional, Preiato, Valentina Lo, additional, Randeva, Harpal S., additional, Ribichini, Danilo, additional, Santos, B.R., additional, Sendur, Suleyman Nahit, additional, Spritzer, P.M., additional, Tilotta, Marco, additional, Tsichlia, Gina, additional, Unfer, Vittorio, additional, Unluturk, Ugur, additional, Vrachnis, Nikolaos, additional, Weickert, Martin O., additional, and Yildiz, Bulent Okan, additional

Published
2022
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8. Dietary Total Polyphenol, Flavonoid, and Lignan Intakes Are Associated with Obesity and Diabetes-Related Traits: A Case-Control Study.

Author

Turan-Demirci, Busra, Isgin-Atici, Kubra, Sendur, Suleyman Nahit, Yuce, Deniz, Erbas, Tomris, and Buyuktuncer, Zehra

Abstract

Purpose: Dietary phytochemicals have been under examination as adjuvants for the prevention and treatment of obesity and diabetes. This study aimed at examining the potential associations of dietary "Phytochemical Index" (PI) and polyphenol intake with obesity and diabetes-related parameters. Materials and Methods: The case-control study involved 331 participants (156 overweight/obese and 175 normal weight), aged 18–50 years. Dietary intake was assessed using the 24-hr dietary recall method, and the PI score was calculated as the percentage of energy intake provided by phytochemical-rich foods. Polyphenol intakes were calculated using Phenol-Explorer and U.S. Department of Agriculture databases. Anthropometrical measurements were taken, serum glucose, insulin, and lipid profiles were analyzed, homeostatic model assessment for insulin resistance (HOMA-IR) was calculated, and blood pressure was measured. Linear regression analyses were used to examine the potential associations. Results: Participants with higher PI scores had higher total and some sub-classes polyphenol intakes compared with lower ones (P < 0.05, for each). Dietary PI score was not associated with any of the anthropometrical measurements; however, total polyphenol and flavonoids intakes were inversely associated with body mass index (β = −0.269, P = 0.049; β = −0.262, P = 0.048; respectively), waist circumference (β = −0.127, P = 0.021; β = −0.130, P = 0.016; respectively), and waist-to-hip ratio (β = −20.724, P = 0.032; β = −22.199, P = 0.018; respectively) after adjusting for potential confounders. Either dietary PI score or total and sub-class polyphenol intakes were not associated with a better metabolic profile, except for the lignan intake, which was inversely associated with HOMA-IR (β = −0.048, P = 0.011). Conclusions: Higher dietary polyphenol intake may have potential in the prevention of obesity and diabetes, and validated practical tools are essential for the assessment of polyphenol intake in clinical practice. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Turkish nationwide survEy of glycemic and other Metabolic parameters of patients with Diabetes mellitus (TEMD study)

Author

Guldiken, Sibel, Ayturk, Semra, Yilmaz, Murat, Asik, Mehmet, Dinccag, Nevin, Cakmak, Ramazan, Turker, Fulya, Idiz, Cemile, Hacisahinogullari, Hulya, Bagdemir, Elif, Yildiz, Busra, Yumuk, Volkan Demirhan, Haliloglu, Ozlem, Sancak, Seda, Ozsari, Levent, Cagiltay, Eylem, Deyneli, Oguzhan, Imre, Eren, Gonen, Sait, Boysan, S. Nur, Altuntas, Yuksel, Ozturk, Feyza Yener, Mert, Meral, Piskinpasa, Hamide, Aydin, Hasan, Imamoglu, Sazi, Ersoy, Canan, Gul, Ozen Oz, Kucuksarac Kiyici, Sinem, Cetinarslan, Berrin, Selek, Alev, Dogru, Teoman, Kirik, Ali, Kebapci, Nur, Efe, Belgin, Kaya, Ahmet, Cordan, Ilker, Baldane, Suleyman, Kirac, Cem Onur, Demirci, Ibrahim, Capa, Zehra, Cesur, Mustafa, Yetkin, Ilhan, Corapcioglu, Demet, Canlar, Sule, Bulent Yildiz, Okan, Sendur, Suleyman Nahit, Cakir, Bekir, Ozdemir, Didem, Corakci, Ahmet, Kutlu, Mustafa, Bascil Tutuncu, Neslihan, Bozkus, Yusuf, Cakal, Erman, Demirbas, Berrin, Ertek, Sibel, Altay, Mustafa, Dagdeviren, Murat, Abedi, Amir Hassein, Cetinkalp, Sevki, Ozisik, Hatice, Oruk, Guzide Gonca, Yener, Serkan, Saydam, Basak Ozgen, Guney, Engin, Unubol, Mustafa, Yaylali, Guzin Fidan, Topsakal, Senay, Hekimsoy, Zeliha, Akbaba, Gulhan, Aslan, Ibrahim, Balci, Mustafa Kemal, Dalkiran, Sefika, Akbay, Esen, Gul, Kamile, Agbaht, Kemal, Yilmaz, Muge Ozsan, Bozkirli, Emre, Tetiker, B. Tamer, Cetinkaya Altuntas, Seher, Atmaca, Aysegul, Durmuş, Elif Tutku, Mete, Turkan, Kutluturk, Faruk, Kucukler, Ferit Kerim, Dikbas, Oguz, Akin, Safak, Nuhoglu, Irfan, Ersoz, Halil Onder, Bayraktaroglu, Taner, Sisman, Pınar, Sahin, Ibrahim, Cetin, Sedat, Capoglu, Ilyas, Akbas, Emin Murat, Ucler, Rıfkı, Eren, Mehmet Ali, Tuzcu, Alpaslan Kemal, Pekkolay, Zafer, Ozkaya, Mesut, Araz, Mustafa, Sonmez, Alper, Haymana, Cem, Bayram, Fahri, Salman, Serpil, Dizdar, Oguzhan Sitki, Gurkan, Eren, Kargili Carlıoglu, Ayse, Barcin, Cem, Sabuncu, Tevfik, and Satman, Ilhan

Published
2018
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20. Reduced irisin levels in patients with acromegaly

Author

Sendur, Suleyman Nahit, primary, Baykal, Gokhan, additional, Firlatan, Busra, additional, Aydin, Busra, additional, Lay, Incilay, additional, Dagdelen, Selcuk, additional, Alikasifoglu, Mehmet, additional, and Erbas, Tomris, additional

Published
2022
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22. Interaction between Dietary Fat Intake and Metabolic Genetic Risk Score on 25-Hydroxyvitamin D Concentrations in a Turkish Adult Population

Author

Isgin-Atici, Kubra, primary, Alathari, Buthaina E., additional, Turan-Demirci, Busra, additional, Sendur, Suleyman Nahit, additional, Lay, Incilay, additional, Ellahi, Basma, additional, Alikasifoglu, Mehmet, additional, Erbas, Tomris, additional, Buyuktuncer, Zehra, additional, and Vimaleswaran, Karani Santhanakrishnan, additional

Published
2022
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27. FTO gene-lifestyle interactions on serum adiponectin concentrations and central obesity in a Turkish population

Author

Isgin-Atici, Kubra, Alsulami, Sooad, Turan-Demirci, Busra, Surendran, Shelini, Sendur, Suleyman Nahit, Lay, Incilay, Karabulut, Erdem, Ellahi, Basma, Lovegrove, Julie A., Alikasifoglu, Mehmet, Erbas, Tomris, Vimaleswaran, Karani Santhanakrishnan, and Buyuktuncer, Zehra

Subjects
nutritional and metabolic diseases
Abstract

The aim of the study was to investigate whether lifestyle factors modify the association between fat mass and obesity-associated(FTO)gene single nucleotide polymorphisms (SNPs) and obesity in a Turkish population. The study included 400 unrelated individuals, aged 24-50 years recruited in a hospital setting. Dietary intake and physical activity were assessed using 24-hour dietary recall and self-report questionnaire, respectively. A genetic risk score (GRS) was developed usingFTOSNPs, rs9939609 and rs10163409. Body mass index and fat mass index were significantly associated withFTOSNP rs9939609 (p = 0.001 andp = 0.002, respectively) and GRS (p = 0.002 andp = 0.003, respectively). The interactions between SNP rs9939609 and physical activity on adiponectin concentrations, and SNP rs10163409 and dietary protein intake on increased waist circumference were statistically significant (P-interaction = 0.027 andP(interaction) = 0.044, respectively). Our study has demonstrated that the association betweenFTOSNPs and central obesity might be modified by lifestyle factors in this Turkish population.

Published
2020

30. FTO gene–lifestyle interactions on serum adiponectin concentrations and central obesity in a Turkish population

Author

Isgin-Atici, Kubra, primary, Alsulami, Sooad, additional, Turan-Demirci, Busra, additional, Surendran, Shelini, additional, Sendur, Suleyman Nahit, additional, Lay, Incilay, additional, Karabulut, Erdem, additional, Ellahi, Basma, additional, Lovegrove, Julie A., additional, Alikasifoglu, Mehmet, additional, Erbas, Tomris, additional, Vimaleswaran, Karani Santhanakrishnan, additional, and Buyuktuncer, Zehra, additional

Published
2020
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35. Turkish nationwide survEy of glycemic and other Metabolic parameters of patients with Diabetes mellitus (TEMD study)

Author

Sonmez, Alper, primary, Haymana, Cem, additional, Bayram, Fahri, additional, Salman, Serpil, additional, Dizdar, Oguzhan Sitki, additional, Gurkan, Eren, additional, Kargili Carlıoglu, Ayse, additional, Barcin, Cem, additional, Sabuncu, Tevfik, additional, Satman, Ilhan, additional, Guldiken, Sibel, additional, Ayturk, Semra, additional, Yilmaz, Murat, additional, Asik, Mehmet, additional, Dinccag, Nevin, additional, Cakmak, Ramazan, additional, Turker, Fulya, additional, Idiz, Cemile, additional, Hacisahinogullari, Hulya, additional, Bagdemir, Elif, additional, Yildiz, Busra, additional, Yumuk, Volkan Demirhan, additional, Haliloglu, Ozlem, additional, Sancak, Seda, additional, Ozsari, Levent, additional, Cagiltay, Eylem, additional, Deyneli, Oguzhan, additional, Imre, Eren, additional, Gonen, Sait, additional, Boysan, S. Nur, additional, Altuntas, Yuksel, additional, Ozturk, Feyza Yener, additional, Mert, Meral, additional, Piskinpasa, Hamide, additional, Aydin, Hasan, additional, Imamoglu, Sazi, additional, Ersoy, Canan, additional, Gul, Ozen Oz, additional, Kucuksarac Kiyici, Sinem, additional, Cetinarslan, Berrin, additional, Selek, Alev, additional, Dogru, Teoman, additional, Kirik, Ali, additional, Kebapci, Nur, additional, Efe, Belgin, additional, Kaya, Ahmet, additional, Cordan, Ilker, additional, Baldane, Suleyman, additional, Kirac, Cem Onur, additional, Demirci, Ibrahim, additional, Capa, Zehra, additional, Cesur, Mustafa, additional, Yetkin, Ilhan, additional, Corapcioglu, Demet, additional, Canlar, Sule, additional, Bulent Yildiz, Okan, additional, Sendur, Suleyman Nahit, additional, Cakir, Bekir, additional, Ozdemir, Didem, additional, Corakci, Ahmet, additional, Kutlu, Mustafa, additional, Bascil Tutuncu, Neslihan, additional, Bozkus, Yusuf, additional, Cakal, Erman, additional, Demirbas, Berrin, additional, Ertek, Sibel, additional, Altay, Mustafa, additional, Dagdeviren, Murat, additional, Abedi, Amir Hassein, additional, Cetinkalp, Sevki, additional, Ozisik, Hatice, additional, Oruk, Guzide Gonca, additional, Yener, Serkan, additional, Saydam, Basak Ozgen, additional, Guney, Engin, additional, Unubol, Mustafa, additional, Yaylali, Guzin Fidan, additional, Topsakal, Senay, additional, Hekimsoy, Zeliha, additional, Akbaba, Gulhan, additional, Aslan, Ibrahim, additional, Balci, Mustafa Kemal, additional, Dalkiran, Sefika, additional, Akbay, Esen, additional, Gul, Kamile, additional, Agbaht, Kemal, additional, Yilmaz, Muge Ozsan, additional, Bozkirli, Emre, additional, Tetiker, B. Tamer, additional, Cetinkaya Altuntas, Seher, additional, Atmaca, Aysegul, additional, Durmuş, Elif Tutku, additional, Mete, Turkan, additional, Kutluturk, Faruk, additional, Kucukler, Ferit Kerim, additional, Dikbas, Oguz, additional, Akin, Safak, additional, Nuhoglu, Irfan, additional, Ersoz, Halil Onder, additional, Bayraktaroglu, Taner, additional, Sisman, Pınar, additional, Sahin, Ibrahim, additional, Cetin, Sedat, additional, Capoglu, Ilyas, additional, Akbas, Emin Murat, additional, Ucler, Rıfkı, additional, Eren, Mehmet Ali, additional, Tuzcu, Alpaslan Kemal, additional, Pekkolay, Zafer, additional, Ozkaya, Mesut, additional, and Araz, Mustafa, additional

Published
2018
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36. gene-lifestyle interactions on serum adiponectin concentrations and central obesity in a Turkish population.

Author

Isgin-Atici, Kubra, Alsulami, Sooad, Turan-Demirci, Busra, Surendran, Shelini, Sendur, Suleyman Nahit, Lay, Incilay, Karabulut, Erdem, Ellahi, Basma, Lovegrove, Julie A., Alikasifoglu, Mehmet, Erbas, Tomris, Vimaleswaran, Karani Santhanakrishnan, and Buyuktuncer, Zehra

Subjects
ADIPONECTIN, OBESITY, SINGLE nucleotide polymorphisms, BODY mass index, PHYSICAL activity, WAIST circumference
Abstract

The aim of the study was to investigate whether lifestyle factors modify the association between fat mass and obesity-associated (FTO) gene single nucleotide polymorphisms (SNPs) and obesity in a Turkish population. The study included 400 unrelated individuals, aged 24-50 years recruited in a hospital setting. Dietary intake and physical activity were assessed using 24-hour dietary recall and self-report questionnaire, respectively. A genetic risk score (GRS) was developed using FTO SNPs, rs9939609 and rs10163409. Body mass index and fat mass index were significantly associated with FTO SNP rs9939609 (p = 0.001 and p = 0.002, respectively) and GRS (p = 0.002 and p = 0.003, respectively). The interactions between SNP rs9939609 and physical activity on adiponectin concentrations, and SNP rs10163409 and dietary protein intake on increased waist circumference were statistically significant (Pinteraction = 0.027 and Pinteraction = 0.044, respectively). Our study has demonstrated that the association between FTO SNPs and central obesity might be modified by lifestyle factors in this Turkish population. [ABSTRACT FROM AUTHOR]

Published
2021
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37. A novel mutation of the menin gene in a family with multiple endocrine neoplasia type 1

Author

Selcuk Dagdelen, Ahmet Bulent Dogrul, Sevgen Onder, Belkis Erbas, Osman Abbasoglu, Serkan Kabacam, Mehmet Alikasifoglu, Tomris Erbas, Cenk Sokmensuer, and Sendur Suleyman Nahit

Subjects
medicine.medical_specialty, Endocrinology, Internal medicine, medicine, Cancer research, Biology, Multiple endocrine neoplasia, medicine.disease, Gene, Novel mutation
Published
2016

41. A case of Woodhouse-Sakati syndrome with pituitary iron deposition, cardiac and intestinal anomalies, with a novel mutation in DCAF17.

Author

Oguz, Sumeyra, Utine, Gulen Eda, Dagdelen, Selcuk, Oguz, Kader Karli, Erbas, Tomris, Alikasifoglu, Mehmet, and Sendur, Suleyman Nahit

Subjects
*DISEASE progression, *SHORT stature, *SYNDROMES, *CARDIAC amyloidosis, *DIABETES
Abstract

Woodhouse-Sakati syndrome is a rare genetic syndrome caused by homozygous mutations of the DCAF17 gene. Several endocrine organs may be affected in the course of the disease. We present a new case with pituitary iron deposition, cardiac and intestinal anomalies, with a novel mutation in DCAF17 gene. An 18-year-old female was admitted because of delayed puberty and amenorrhea. Hormonal evaluation revealed combined hyper-hypogonadotropic hypogonadism. GH and IGF-1 levels were low without short stature. ACTH levels were high and cortisol levels were supranormal with the lack of clinical findings of cortisol excess or deficiency. Pituitary MRI indicated paramagnetic substance deposition in gland. On follow-ups, non-autoimmune, insulinopenic diabetes mellitus and secondary hypothyroidism emerged. Woodhouse-Sakati syndrome was diagnosed on the basis of consistent clinical context and subsequently a novel mutation in DCAF17 was detected. [ABSTRACT FROM AUTHOR]

Published
2019
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42. FTO gene-lifestyle interactions on serum adiponectin concentrations and central obesity in a Turkish population.

Author

Isgin-Atici K, Alsulami S, Turan-Demirci B, Surendran S, Sendur SN, Lay I, Karabulut E, Ellahi B, Lovegrove JA, Alikasifoglu M, Erbas T, Vimaleswaran KS, and Buyuktuncer Z

Subjects
Adult, Body Mass Index, Case-Control Studies, Cross-Sectional Studies, Diet, Exercise, Female, Humans, Male, Middle Aged, Nutritional Status, Obesity epidemiology, Polymorphism, Single Nucleotide, Turkey epidemiology, Waist Circumference, Young Adult, Adiponectin blood, Adiponectin genetics, Alpha-Ketoglutarate-Dependent Dioxygenase FTO genetics, Life Style, Obesity, Abdominal epidemiology
Abstract

The aim of the study was to investigate whether lifestyle factors modify the association between fat mass and obesity-associated (FTO) gene single nucleotide polymorphisms (SNPs) and obesity in a Turkish population. The study included 400 unrelated individuals, aged 24-50 years recruited in a hospital setting. Dietary intake and physical activity were assessed using 24-hour dietary recall and self-report questionnaire, respectively. A genetic risk score (GRS) was developed using FTO SNPs, rs9939609 and rs10163409. Body mass index and fat mass index were significantly associated with FTO SNP rs9939609 ( p  = 0.001 and p  = 0.002, respectively) and GRS ( p  = 0.002 and p  = 0.003, respectively). The interactions between SNP rs9939609 and physical activity on adiponectin concentrations, and SNP rs10163409 and dietary protein intake on increased waist circumference were statistically significant ( P interaction  = 0.027 and P interaction  = 0.044, respectively). Our study has demonstrated that the association between FTO SNPs and central obesity might be modified by lifestyle factors in this Turkish population.

Published
2021
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