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114 results on '"Senmaru, Naoto"'

1. A new technique to avoid unintentional adhesion while deploying ProGrip mesh and its utility in the laparoscopic repair of obturator hernia

Author

Muto, Jun, Murakawa, Katsuhiko, Yamamoto, Hiroyuki, Poudel, Saseem, Sato, Shoki, Kato, Kohei, Senmaru, Naoto, and Ono, Koichi

Subjects
Laparoscopy -- Methods, Laparoscopic surgery -- Methods, Hernia -- Methods, Health
Abstract

Byline: Jun. Muto, Katsuhiko. Murakawa, Hiroyuki. Yamamoto, Saseem. Poudel, Shoki. Sato, Kohei. Kato, Naoto. Senmaru, Koichi. Ono The ProGrip[TM] laparoscopic self-fixating mesh provides advantages such as low cost and reduced [...]

Published
2021

4. Impact of elemental diet on early recovery after laparoscopic colectomy: findings of a randomized controlled trial

Author

Shichinohe, Toshiaki, Sasaki, Takeshi, Kitashiro, Shuji, Morita, Takayuki, Ono, Koichi, Senmaru, Naoto, Ikeda, Junichi, Kojima, Tetsufumi, Kyogoku, Noriaki, Yamada, Hidehisa, Sato, Nagato, Kato, Kentaro, Murakami, Soichi, Ebihara, Yuma, Kurashima, Yo, Tamoto, Eiji, Noji, Takehiro, Nakamura, Toru, Okamura, Keisuke, Tsuchikawa, Takahiro, and Hirano, Satoshi

Published
2017
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7. Laparoscopic approach as a safe and effective option for incarcerated femoral hernias.

Author

Okazaki, Ryo, Poudel, Saseem, Hane, Yuma, Saito, Takahiro, Muto, Jun, Syoji, Yasuhito, Hase, Ryunosuke, Senmaru, Naoto, and Hirano, Satoshi

Subjects
HERNIA surgery, LAPAROSCOPIC surgery, HERNIA, SURGICAL emergencies, WATER pressure
Abstract

Introduction: The laparoscopic approach for elective femoral herniorrhaphy is well established. However, femoral hernias often present as incarcerations and require emergency repair surgery, mainly using the open approach. This study aimed to retrospectively analyze the efficacy of the laparoscopic approach for incarcerated femoral hernias. Methods: Data of patients who underwent emergency surgery for incarcerated femoral hernia between April 2016 and August 2021 were retrospectively analyzed. Laparoscopy was performed whenever possible; however, conversion to an open approach remained a fallback option for when laparoscopic repair was not possible. In laparoscopic repair, incarcerated femoral hernias reduced using traction, water pressure, and preperitoneal methods. Data of patients who underwent open repair and laparoscopy were then compared. Results: During the observation period, 20 patients underwent emergency surgery for incarcerated femoral hernia. Eleven patients subsequently underwent repair using a laparoscopic approach, and eight underwent repair using an open approach. Only one patient underwent intestinal resection without hernia repair due to perforated bowel. Operative time for laparoscopic repair was longer. Mesh repair was performed in 18 patients. Four patients each in the laparoscopic repair and open group required intestinal resection. Conclusion: Incarcerated femoral hernias can be safely repaired using the laparoscopic approach. [ABSTRACT FROM AUTHOR]

Published
2022
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13. PEDUNCULATED GASTRIC SIGNET RING CELL CARCINOMA

Author

OKU, TAKATOMI, MAEDA, MASAHIRO, ONO, KAORU, NAGAMACHI, YASUHIRO, FUJII, SHIGEYUKI, FUJITA, MIRI, MISU, KENJIRO, SENMARU, NAOTO, SUZUKI, YASUHIRO, NAGASHIMA, KAZUO, and NIITSU, YOSHIRO

Published
2008

14. Impact of elemental diet on early recovery after laparoscopic colectomy : findings of a randomized controlled trial

Author

1000070374353, Shichinohe, Toshiaki, Sasaki, Takeshi, Kitashiro, Shuji, Morita, Takayuki, Ono, Koichi, Senmaru, Naoto, Ikeda, Junichi, Kojima, Tetsufumi, Kyogoku, Noriaki, Yamada, Hidehisa, Sato, Nagato, 1000050508885, Kato, Kentaro, Murakami, Soichi, 1000050632981, Ebihara, Yuma, 1000040374350, Kurashima, Yo, Tamoto, Eiji, 1000010739296, Noji, Takehiro, 1000070645796, Nakamura, Toru, Okamura, Keisuke, 1000050507572, Tsuchikawa, Takahiro, 1000050322813, Hirano, Satoshi, 1000070374353, Shichinohe, Toshiaki, Sasaki, Takeshi, Kitashiro, Shuji, Morita, Takayuki, Ono, Koichi, Senmaru, Naoto, Ikeda, Junichi, Kojima, Tetsufumi, Kyogoku, Noriaki, Yamada, Hidehisa, Sato, Nagato, 1000050508885, Kato, Kentaro, Murakami, Soichi, 1000050632981, Ebihara, Yuma, 1000040374350, Kurashima, Yo, Tamoto, Eiji, 1000010739296, Noji, Takehiro, 1000070645796, Nakamura, Toru, Okamura, Keisuke, 1000050507572, Tsuchikawa, Takahiro, 1000050322813, and Hirano, Satoshi

Abstract

Purpose: An amino acid-containing elemental diet (ED) does not require digestion for nutritional absorption, making it a good option for patients with gastrointestinal malabsorption. We conducted a randomized trial to confirm that perioperative ED enhanced the recovery of patients undergoing laparoscopic colectomy. Methods: Patients in the intervention arm received commercially available ED from the day prior to surgery until postoperative day (POD) 3, whereas patients in the control group received a conventional perioperative diet program. To verify the endpoints, "estimated minimum length of stay in hospital after surgery" (emLOS) was defined as the number of days necessary to reach all the five criteria; namely, "sufficient oral intake", "sufficient pain control", "withdrawal of intravenous alimentation", "no abnormal findings in routine examinations", and "no rise in fever". Results: A total of 102 patients were randomized, 94 of whom were analyzed (ED 45, control 49). There was no morbidity or mortality. Shorter emLOS (POD 4 vs. POD 7; p = 0.018), earlier resumption of sufficient oral intake (POD 3 vs. POD 4; p = 0.034) and faster recovery to defecation (2.2 vs. 3.1 days; p = 0.005) were observed in the ED group vs. the control group. Conclusions: The perioperative ingestion of ED by patients undergoing laparoscopic colectomy is safe and can reduce the postoperative hospital stay by supporting the acceleration of oral intake.

Published
2017

15. North Japan multicenter phase II study of oxaliplatin-containing regimen as adjuvant chemotherapy for stage III colon cancer (NORTH/HGCSG1003).

Author

Shichinohe, Toshiaki, primary, Yuki, Satoshi, additional, Takahashi, Norihiko, additional, Nakatsumi, Hiroshi, additional, Kawamoto, Yasuyuki, additional, Kusumi, Takaya, additional, Ishiguro, Atsushi, additional, Sogabe, Susumu, additional, Iwanaga, Ichiro, additional, Hatanaka, Kazuteru, additional, Oomori, Kazuyoshi, additional, Nakamura, Michio, additional, Senmaru, Naoto, additional, Iwai, Kazuhiro, additional, Koike, Masahiko, additional, Sakamoto, Naoya, additional, Taketomi, Akinobu, additional, Hirano, Satoshi, additional, Ito, Yoichi M, additional, and Komatsu, Yoshito, additional

Published
2017
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17. Resection of lung metastasis from gallbladder carcinoma: immunohistochemistry of RCASI and CD8(+)T cells in primary and metastatic tumors

Author

Oshikiri, Taro, Morita, Takayuki, Fujita, Miyoshi, Miyasaka, Yuji, Senmaru, Naoto, Yamada, Hidehisa, Kaji, Naoto, and Kondo, Satoshi

Subjects
RCAS1, immunohistochemistry, CD8 T cells, thyroid transcription factor 1, 494.5
Abstract

Advanced Gallbladder cancer has an extremely poor prognosis. We examined a patient with resectable gallbladder cancer with associated lung metastasis. A 64-year-old female patient, diagnosed with gallbladder cancer and a solitary benign lung tumor by imaging, was subjected to extensive cholecystectomy and extrahepatic bile duct resection. After one year, a follow-up CT indicated enlargement of the lung tumor; video-assisted right middle lobectomy was then performed. The lung tumor was diagnosed as a metastasis derived from the gallbladder cancer by pathology and immunohistochemistry. Expression of RCAS1, an independent unfavorable prognostic indicator in gallbladder cancer, was observed in both the gallbladder and lung tumors. However, infiltration of CD8+T cells was only seen in the lung metastatic tumor. She has remained free of any evidence of recurrence in the 10 months and 4 years after the first surgery. The results that metastasis is solitary and infiltrated by CD8+T cells correspond with the present clinical history.

Published
2006

18. Risk Factors for Difficult Laparoscopic Cholecystectomy in Acute Cholecystitis

Author

Hayama, Satoshi, Ohtaka, Kazuto, Shoji, Yasuhito, Ichimura, Tatsunosuke, Fujita, Miri, Senmaru, Naoto, 1000050322813, Hirano, Satoshi, Hayama, Satoshi, Ohtaka, Kazuto, Shoji, Yasuhito, Ichimura, Tatsunosuke, Fujita, Miri, Senmaru, Naoto, 1000050322813, and Hirano, Satoshi

Abstract

Background and Objectives: Factors that contribute to difficult laparoscopic cholecystectomy (LC) in acute cholecystitis (AC) that would affect the performance of early surgery remain unclear. The purpose of this study was to identify such risk factors. Methods: One hundred fifty-four patients who underwent LC for AC were retrospectively analyzed. The patients were categorized into early surgery and delayed surgery. Factors predicting difficult LC were analyzed for each group. The operation time, bleeding, and cases of difficult laparoscopic surgery (CDLS)/conversion rate were analyzed as an index of difficulty. Analyses of patients in the early group were especially focused on 3 consecutive histopathological phases: edematous cholecystitis (E), necrotizing cholecystitis (N), suppurative/subacute cholecystitis (S). Results: In the early group, the CDLS/conversion rate was highest in necrotizing cholecystitis. Its rate was significantly higher than that of the other 2 histopathological types (N 27.9% vs E and S 7.4%; P = .037). In the delayed-surgery group, a higher white blood cell (WBC) count and older age showed significant correlations with the CDLS/conversion rate (P = .034 and P = .004). Conclusion: In early surgery, histopathologic necrotizing cholecystitis is a risk factor for difficult LC in AC. A higher WBC count and older age are risk factors for delayed surgery.

Published
2016

19. Noninvasive management for iatrogenic splenic injury caused by chest tube insertion : a case report

Author

Ohtaka, Kazuto, Hase, Ryunosuke, Chiba, Ryohei, Miyasaka, Mamoru, Sato, Shoki, Shoji, Yasuhito, Ichimura, Tatsunosuke, Senmaru, Naoto, 1000080224335, Kaga, Kichizo, 1000090219379, Matsui, Yoshiro, Ohtaka, Kazuto, Hase, Ryunosuke, Chiba, Ryohei, Miyasaka, Mamoru, Sato, Shoki, Shoji, Yasuhito, Ichimura, Tatsunosuke, Senmaru, Naoto, 1000080224335, Kaga, Kichizo, 1000090219379, and Matsui, Yoshiro

Published
2016

21. Impact of elemental diet on early recovery after laparoscopic colectomy: findings of a randomized controlled trial

Author

Shichinohe, Toshiaki, primary, Sasaki, Takeshi, additional, Kitashiro, Shuji, additional, Morita, Takayuki, additional, Ono, Koichi, additional, Senmaru, Naoto, additional, Ikeda, Junichi, additional, Kojima, Tetsufumi, additional, Kyogoku, Noriaki, additional, Yamada, Hidehisa, additional, Sato, Nagato, additional, Kato, Kentaro, additional, Murakami, Soichi, additional, Ebihara, Yuma, additional, Kurashima, Yo, additional, Tamoto, Eiji, additional, Noji, Takehiro, additional, Nakamura, Toru, additional, Okamura, Keisuke, additional, Tsuchikawa, Takahiro, additional, and Hirano, Satoshi, additional

Published
2016
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23. Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y

Author

Senmaru, Naoto, Shichinohe, Toshiaki, Takeuchi, Motoya, Miyamoto, Masaki, Sazawa, Ataru, Ogiso, Yoshifumi, Takahashi, Toshiyuki, Okushiba, Shyunichi, Takimoto, Masato, Kato, Hiroyuki, and Kuzumaki, Noboru

Subjects
491.65
Abstract

Our previous studies demonstrated that introduction of a dominant negative H-ras mutant, N116Y, inhibits the growth of various types of cancer cells in vitro. In this study, we tested the efficacy of N116Y in blocking the growth of esophageal cancer cells using an adenoviral vector. Infection with N116Y adenovirus, (AdCMV-N116Y), in which N116Y expression is driven by the cytomegalovirus promoter, significantly reduced the in vitro growth of all esophageal cancer cell lines studied. Esophageal cancer cells that contained wild-type K-ras and H-ras (TE8, SGF3, SGF7) were more sensitive to AdCMV-N116Y than HEC46 cells that expressed mutant K-ras protein.Most importantly, direct injection of AdCMVN116Y into TE8-or SGF3-induced tumors in nude mice suppressed their growth significantly. To examine the suppressive mechanism of N116Y, cell cycle profile and the activation of extracellular signal-regulated kinase 2 (Erk2) were examined by flow cytometry and Western blot analysis, respectively. In TE8 cells, progression into S phase was clearly blocked after infection with AdCMV-N116Y. Infection with AdCMV-N116Y did not strongly suppress the activation of Erk2 after EGF stimulation in serum-starved HEC46 cells, whereas it completely suppressed activation in TE8, SGF3 and SGF7 cells. Our observations suggest that N116Y reduces growth of human esophageal cancer cells and suppresses the activation of Erk2; they also indicate that N116Y is a potential candidate gene for human esophageal cancer gene therapy.

Published
1998

24. Long-term survival after repeated resection of metachronous lung metastases from pStage IA pancreatic adenocarcinoma.

Author

Miyasaka, Mamoru, Noji, Takehiro, Ohtaka, Kazuto, Chiba, Ryohei, Sato, Shoki, Shoji, Yasuhito, Hase, Ryunosuke, Ichimura, Tatsunosuke, Hirano, Satoshi, and Senmaru, Naoto

Abstract

Case report: A 70-year-old woman with pancreatic ductal adenocarcinoma was initially treated by distal pancreatectomy (DP). Thirty-five months later, another tumor appeared in the pancreatic head and was treated by pancreaticoduodenectomy. Histopathological findings identified both tumors as pancreatic ductal adenocarcinoma pStage IA. Computed tomography (CT) of the chest 16 months after the second pancreatectomy revealed a ground-glass opacity in segment 3 of the right lung. Chest CT 23 months after the second pancreatectomy revealed a nodular shadow in segment 1a of the right lung. Chest CT 39 months after the second pancreatectomy revealed a nodular shadow in segment 5 of the left lung. These lesions were treated by video-assisted thoracoscopic surgery partial resection. Histopathological and immunohistochemical features (positive for cytokeratin (CK)7 and CK20, negative for transcription factor-1) for these three lesions and the secondary pancreatic ductal adenocarcinoma were similar, indicating a diagnosis of lung metastasis from the second pancreatic ductal adenocarcinoma. The patient has remained alive and free of new metastases for 8 years after initial DP, 3 years after the last lung resection.Conclusion: This patient has survived over the long term after undergoing three resections of lung metastases from resected pancreatic ductal adenocarcinoma. [ABSTRACT FROM AUTHOR]

Published
2018
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25. Left upper lobectomy can be a risk factor for thrombosis in the pulmonary vein stump

Author

Ohtaka, Kazuto, 1000030399919, Hida, Yasuhiro, 1000080224335, Kaga, Kichizo, Takahashi, Yasuhiro, Kawase, Hiroshi, Hayama, Satoshi, Ichimura, Tatsunosuke, Senmaru, Naoto, Honma, Naotake, 1000090219379, Matsui, Yoshiro, Ohtaka, Kazuto, 1000030399919, Hida, Yasuhiro, 1000080224335, Kaga, Kichizo, Takahashi, Yasuhiro, Kawase, Hiroshi, Hayama, Satoshi, Ichimura, Tatsunosuke, Senmaru, Naoto, Honma, Naotake, 1000090219379, and Matsui, Yoshiro

Abstract

Background: Thrombosis in the left upper pulmonary vein stump after left upper lobectomy is a very rare but important complication because it occurs in the systemic circulation system. We previously made the first ever report on the frequency and risk factors of thrombosis in the pulmonary vein stump after lobectomy. In this study, we conducted an investigation in a different hospital to determine whether this was a common complication. Methods: From 2008 to 2012, 151 patients who underwent lobectomy and following enhanced CT within 2 years after the operation were studied. Postoperative contrast-enhanced CT imaging was retrospectively checked. Results: We found thrombosis in the pulmonary vein stump in 5 of the 151 patients (3.3%). All 5 patients underwent left upper lobectomy (17.9% of the patients who underwent left upper lobectomy). These 5 patients did not have infarction of any vital organ. The thrombus was disappeared several months later on contrast-enhanced CT in 3 patients and followed in 2 patients. On univariate analysis, there was a significant difference only in the operative procedure (p < 0.001). Conclusions: Thrombosis in the pulmonary vein stump occurred with high frequency in patients who underwent left upper lobectomy. Because the frequency of thrombosis in this study was the same as in our previous report, this might be a common complication.

Published
2014

30. Randomized phase III clinical study comparing postoperative UFT/LV,UFT+LV/UFT and UFT+LV+PSK/UFT+PSK as adjuvant therapy for curatively resected stage III colorectal cancer HGCSG-CAD study.

Author

Shichinohe, Toshiaki, primary, Komatsu, Yoshito, additional, Akazawa, Kohei, additional, Yuki, Satoshi, additional, Fukushima, Hiraku, additional, Ohno, Kouichi, additional, Nakamura, Fumitaka, additional, Kusumi, Takaya, additional, Morita, Takayuki, additional, Senmaru, Naoto, additional, Kumagai, Naoko, additional, and Hirano, Satoshi, additional

Published
2013
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36. PEDUNCULATED GASTRIC SIGNET RING CELL CARCINOMA

Author

Oku, Takatomi, primary, Maeda, Masahiro, additional, Ono, Kaoru, additional, Nagamachi, Yasuhiro, additional, Fujii, Shigeyuki, additional, Fujita, Miri, additional, Misu, Kenjiro, additional, Senmaru, Naoto, additional, Suzuki, Yasuhiro, additional, Nagashima, Kazuo, additional, and Niitsu, Yoshiro, additional

Published
2007
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