Search

Objectives: Coronary artery bypass graft (CABG) surgeries are the most beneficial treatment method for atherosclerotic heart disease. Prolonged ventilation is a significant condition that poses risks such as infection, renal failure, prolongs hospital stays, and increases treatment costs. In this current study, we aimed to reveal the relationship between prolonged mechanical ventilation and Glasgow Prognostic Score (GPS), in patients aged 65 years and older who underwent isolated CABG. Methods: Patients aged 65 years and over who underwent elective isolated coronary bypass surgery with cardiopulmonary bypass in our clinic, between June 2017 and June 2022, were included in the study retrospectively. The patients who were extubated within eight hours of the surgeries were determined as Group 1, whereas those who were extubated after 8 hours were determined as Group 2. Results: Prolonged ventilation occurred in 101 (20.7%) patients (Group 2). The median age of the 385 patients included in Group 1 and 101 patients in Group 2 was 68 (66 to 91) and 71 (66 to 88) years, respectively (p = 0.216). The two groups were similar in regards to gender, hypertension, smoking, diabetes mellitus, body mass index, history of cerebrovascular accident and left ventricular ejection fraction rates. In the multivariate analysis, left ventricular ejection fraction

Objectives: Various vascular grafts are used in coronary artery bypass graft (CABG) surgeries, however, the most commonly used one is the saphenous vein graft (SVG). Various studies conducted on this topic have found a relationship between uric acid to HDL-C (UHR) and cardiovascular diseases. In this current study, we aimed to investigate the predictive importance of UHR value in predicting long-term SVG disease in patients who underwent CABG surgery. Methods: Patients who had a history of CABG surgery at least one year prior, had stable angina pectoris, and underwent coronary angiography between January 01, 2016 and January 01, 2020, were included in the study retrospectively. Patients with open saphenous veins were defined as Group 1, and patients who had 50% or more stenosis in at least one SVG after coronary angiography, were defined as Group 2. Results: The median age of the 204 patients included in Group 1 and 292 patients in Group 2 were 65 (38-77) years and 66 (45-79) years, respectively (p = 0.251). The two groups were similar in terms of gender, hypertension, chronic obstructive pulmonary disease rates, history of cerebrovascular events, ejection fraction, body mass index, and current medical treatments. In univariate analysis, SVG disease was found to significantly correlate with diabeter mellitus (odds ratio [OR]: 1.644, 95% confidence interval [CI]: 1.190-1.985, p = 0.008), current smoking (OR: 0.875, 95% CI: 0.669-0.940, p = 0.030), number of patients with target artery diameter < 1.5 mm (OR: 1.945, 95% CI: 1.221-2.398, p < 0.001), age of SVG (OR: 2.960, 95% CI: 1.980-4.168, p < 0.001), uric acid (OR: 1.241, 95% CI: 1.078-1.592, p = 0.004), triglyceride (OR: 0.780, 95% CI: 0.569-0.935, p = 0.044) and UHR (OR: 1.894, 95% CI: 1.384-2.896, p < 0.001). Conclusions: In this study, we showed that we can predict saphenous vein graft occlusion with serum UHR value.

Objectives: In the present study, the purpose was to investigate the usability of the preoperative C-reactive protein/albumin ratio as a predictor of the development of postoperative atrial fibrillation in patients who undergo coronary artery bypass grafting. Patients and methods: A total of 336 patients (228 males, 108 females; mean age: 58.1±8.5 years; range 35 to 88 years) who underwent isolated coronary artery bypass grafting with cardiopulmonary bypass between January 2019 and January 2021 were reviewed in the single-center, retrospective study. Those with postoperative sinus rhythm were considered Group 1 (n=258), and patients with postoperative atrial fibrillation were defined as Group 2 (n=78). Preoperative routine biochemical tests of the patient groups were evaluated. Results: The incidence of postoperative atrial fibrillation was 23.2%. Statistically significant differences were detected between the two groups in terms of age (p

Cardiovascular diseases are among the leading causes of death worldwide. Atherosclerotic cardiovascular diseases consist of a broad spectrum of diseases such as coronary artery disease, carotid artery disease, peripheral artery diseases, cerebral vascular diseases and visceral artery diseases. Although atherosclerosis occurs over time due to age; hypertension, hyperlipidemia, smoking, and diabetes mellitus are important factors that play a role in the emergence of atherosclerosis. Diabetes mellitus has an active role in the development of atherosclerotic cardiovascular disease. It is expected that there will be a significant increase in the incidence of diabetes-related cardiovascular diseases in the future. In this review, it is aimed to review the coexistence of diabetes with different cardiovascular diseases and its menanisms.

Objectives: Total circulatory arrest (TCA) technique is a method used in cardiac surgery accompanied by cardiopulmonary bypass (CPB). It has been shown that Tulbaghia violacea extract increases antioxidant capacity, regulates blood pressure, decreases lipid peroxide, and reduces atherosclerosis. In this experimental study, we aimed to investigate the effect of T. violacea extract administration on serum oxidative stress parameters (Total antioxidant status [TAS], total oxidant status [TOS] and oxidative stress index [OSI] and deoxyribonucleic acid [DNA] damage level with 8-Hydroxy-2-Deoxyguanosine [8-OHdG]) and histopathological changes in the heart and other organs in rats with deep circulatory arrest model.Methods: In this study, 48 Wistar Albino adult rats, 24 female and 24 male, obtained from Harran University Experimental Animals Research Center were used. The average weight of female rats was 250-300 g, and the average weight of male rats was 450-500 g. These rats were randomly divided into four groups. 6 male and 6 female rats were used in each group (Group 1 = Sham, Group 2 = Injury, Group 3 = Treatment and Injury, Group 4 = Treatment).Results: As a result of this experimental study, the changes in the biochemical 8-OHdG, TOS, OSI and TAS levels of the groups were found to be statistically significant (p < 0.001). In the subgroup analyzes of the data, 8-OHdG level, which is an oxidative DNA damage marker in Group 2 was higher than the Group 1, Group 3 and Group 4 and there was a statistically significant difference (p < 0.001, p = 0.027 and p < 0.001; respectively). The TOS level of the injury group was higher than Group 1, Group 3 and Group 4 and there was a statistically significant difference (p < 0.001, p = 0.003 and p < 0.001; respectively).Conclusions: As a result of our study, we revealed that T. violacea extract has a protective effect on organ and tissue damage in the TCA model.

Objectives: In the last 2 years with the new type of coronavirus infection (COVID-19) pandemic, it has become inevitable to adapt to this disease in cardiovascular surgery procedures. In this study, we aimed to investigate the effects of the results of respiratory tract samples taken from different places in patients undergoing cardiac surgery on our postoperative patient follow-up procedures and to share our cardiac surgery experiences during the pandemic period. Methods: A total of 177 patients who underwent cardiac surgery were included in this study. Endobronchial lavage samples were obtained from the intubated patients through the endotracheal tube in the early postoperative period. According to the Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) results obtained in the early postoperative period, the patients were divided into 2 groups as Group 1 for those with negative PCR and Group 2 for those with positive PCR. After that a total of 59 patients who were found to have COVID-19 were divided into 2 groups as survivors and non-survivors. Results: There were 118 (66.6%) patients in Group 1 and 59 (33.3%) in Group 2. The mean ages of patients in Group 1 and Group 2 were 64.5 ± 9.8 years and 61.9 ± 10.1 years, respectively (p = 0.174). Mortality was significantly higher in Group 2 (n = 24, 40.6%) compared Group 1 (n = 2, 1.6%) (p < 0.001). After that a total of 59 patients who were found to have COVID-19 were divided into 2 groups as survivors (n = 35, 59.3%) and non-survivors (n = 24, 40.7%). There was no statistically significant difference between the groups in terms of gender, smoking, diabetes mellitus, hypertension, chronic renal failure, chronic obstructive pulmonary diseas rates and surgery types (p > 0.05). Conclusions: The COVID-19 pandemic has significantly affected our cardiovascular surgery practice. In addition to being negative for PCR at least 2 times in routine preoperative preparations, obtaining endobronchial lavage samples for PCR testing from the endotracheal tube in the early postoperative period plays an important role in patient management.

In most adult cardiac surgery operations, the heart must be completely immobile and isolated from the blood. Therefore, the heart is stopped in diastole and a still operative site is obtained. Cardiac arrest results in ischemia-reperfusion injury. For these reasons, myocardial protection and the prevention of damages are required. Various cardioplegia solutions are used for this purpose. It can be said that cardioplegia is the gold standard method of myocardial protection in cardiac arrest. Nowadays, "Single-dose cardioplegia" applications are increasingly used, especially in minimally invasive cardiac surgery and basic coronary bypass procedures due to the advantages they provide, which include reduction of aortic cross-clamp time, prevention of frequent interruption of the procedure due to cardioplegia, and reduced postoperative myocardial dysfunction incidence. The two main solutions used in single dose cardioplegia applications are the Bretschneider solution and the del Nido extracellular cardioplegia solution. The del Nido cardioplegia solution (dNCS), which was originally developed for use in pediatric cardiac surgery, has recently increased its use in adult cardiac surgery due to straightforward application and long-term effectiveness. The del Nido cardioplegia reduces the aortic cross clamp duration, cardiopulmonary bypass time and required cardioplegia solution volume, and is a safer and superior cardioplegia solution and technique in terms of myocardial protection with regards to many organs and cardiac-biochemical parameters.

SUMMARY OBJECTIVE: Postoperative acute kidney injury is an important problem that can occur after coronary artery bypass graft operations, and it is important to identify risky patient groups preoperatively. This study aimed to investigate the importance of preoperative syndecan-1 levels in predicting acute kidney injury after elective coronary artery bypass graft operations accompanied by cardiopulmonary bypass. METHODS: Patients who underwent coronary artery bypass graft operation in our clinic between March 1 and May 10, 2022, were included in this prospective study. Patients who did not develop acute kidney injury in the postoperative period were recorded as group 1 and patients who developed it were recorded as group 2. RESULTS: A total of 79 patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass were included in the study. There were 55 patients in group 1 and 24 patients in group 2. There was no difference between the groups in terms of age, gender, diabetes mellitus, body mass index, smoking, and hyperlipidemia rates. In multivariate logistic regression analysis, increased blood product use (odds ratio 1.634; 95%CI 1.036–2.579; p=0.035), preoperative high creatinine (odds ratio 59.387; 95%CI 3.034–1162.496; p=0.007), and high syndecan-1 (odds ratio 1.015; 95%CI 1.002–1.028; p=0.025) were independent predictors of acute kidney injury. CONCLUSION: This study revealed that elevated preoperative syndecan-1 is associated with acute kidney injury after isolated coronary artery bypass graft accompanied by cardiopulmonary bypass and has prognostic utility independent of other recognized risk factors.

Objectives Varicose veins that cannot be seen with the naked eye can be easily detected with Near Infrared (NIR) light. With a minimally invasive procedure performed with NIR light guided, the need for reoperation is reduced, while optimal treatment of venous insufficiency and symptoms is provided. In this study, the detection of residual varicose veins after varicose vein surgery using NIR light and the results of treatment of sclerotherapy were investigated. Methods In this retrospective study, treatment and clinical outcomes of patients’ who underwent NIR light-guided foam sclerotherapy for Clinical-Etiology-Anatomy-Pathophysiology (CEAP) (C1, C2) stage residual varicose veins after surgical varicose treatment between 2014 and 2017 were examined. Data of patients who underwent foam sclerotherapy with NIR light were collected and analyzed. Results A total of 151 patients and 171 lower extremity varicose veins were treated with surgery. 55 (35.7%) of the patients were male, and 96 (62.3%) were female. Their age ranges from 20 to 64, with an average age of 45.38. 4 (2.6%) of the patients had phlebectomy. 137 of patients (90.7%) had ligation of perforated veins, phlebectomy, and great saphenous vein (GSV) stripping, 10 of patients (6.6%) had GSV stripping, perforating vein ligation, phlebectomy, and small saphenous vein (SSV) surgery. No residual leakage was observed in the controls of GSV, SSV, and perforating veins by duplex ultrasonography (DUS). In the first month after varicose surgery, an average of 1.64 ± 1.05 sessions of sclerotherapy was applied to patients with CEAP C1, C2 stage residual varicose veins. 70 patients had one session of sclerotherapy, 37 patients had two sessions of sclerotherapy, 20 patients had three sessions of sclerotherapy, and 11 patients had four sessions of sclerotherapy administrated. The need for complementary therapy was required for all female patients; 13 of the male patients did not require complementary sclerotherapy. While single-session sclerotherapy was applied to most male patients (32 (58.18%), 10 (18.18%) patients received two sclerotherapy sessions. After completing sclerotherapy, 7 (4.63%) patients had superficial venous thrombosis, and 13 (8.60%) patients had hyperpigmentation. Conclusion Surgical treatment is a safe and effective technique in venous insufficiency. Nevertheless, residual varicose veins may remain, and these can be detected noninvasively with NIR light. Foam sclerotherapy with NIR light is a minimally invasive and safe treatment method for small residual varicose veins after the operation. We think that sclerotherapy with NIR light as a complementary treatment is a practical, reliable, and demanding treatment for clinical improvement, especially in female patients.

Aim: Acute Type A aortic dissection (ATAAD) is an important clinical condition that requires urgent surgical intervention. Various organ failures and the development of postoperative pneumonia are also important problems. In this study, we aimed to investigate the value of admission blood glucose (ABG)/estimated average glucose (eAG) ratio in predicting the development of postoperative pneumonia after ATAAD surgery. Material and Methods: Patients who were operated for ATAAD between January 2016 and January 2022 were consecutively included in the study. Patients who did not develop pneumonia in the postoperative period were recorded as Group 1, and those who did develop as Group 2. Results: A total of 124 patients were included in the study. Those who did not develop postoperative pneumonia were included in Group 1 (N = 92, median age = 63.7±9.2 years), and those who did were included in Group 2 (N = 32, median age = 66.9±9.6 years). As a result of multivariate analysis, ventilation time (OR: 1.114 CI 95%: 1.030-1.542, P=0.023), and ABG/eAG ratio (OR: 0.886, CI 95%: 0.695-0.990, P=0.009) values were determined as independent predictors for predicting postoperative pneumonia. Conclusion: In this study, we showed that the ABG/eAG ratio obtained from the blood values of the patients at the time of admission is an important predictor for the development of postoperative pneumonia

Objectives: An exaggerated inflammatory immune response is observed in cases of COVİD 19. This study aims to evaluate the effects of vitamin C, as a significant modulator of inflammation, on the inflammatory parameters and mortality in patients followed up in the intensive care unit (ICU) during the pandemic. Methods: This single-center retrospective study included 160 adult patients with confirmed positive nasopharyngeal smear COVID-19 PCR test results, who were followed up in the ICU between 01 March and 01 August 2020. Hospital files were scanned and patients given and not given vitamin C were assigned, to Group 1 and Group 2, respectively. The Acute Physiology and Chronic Health Evaluation (APACHE II) scores, the data entries on demographics, ventilation, laboratory tests, duration of ICU stay, discharge, and mortality were compared. Interventions with antiviral and antibacterial agents. steroids, cytokine apheresis, and renal replacement therapy were evaluated. Results: Vitamin C treatment was started in patients with raised neutrophil/lymphocyte ratio (NLR) at admission to ICU, who made up 20% of the total 160 ICU patients. Mortality incidence was higher among patients with raised NLR. Vitamin C at the doses used did not affect the inflammatory parameters, length of stay or mortality, and 37.5% of the patients recovered and were discharged from the ICU. Conclusions: We think that vitamin C treatment will have positive effects on the initiation of COVID-19 and that the time of intiation of the therapy and the optimal doses used should be determined with prospective studies.

As the industry made progress, human labor force gained importance as an element of work life. The science of ergonomics came into being in order to take necessary precautions by determining the convenience of human motions with anatomy and risks and possible dangers during work. Through the methods of risk assessment, risks and possible dangers are determined to create a healthy environment for workers. Through REBA and RULA risk assessment methods, worker motions and postures are studied to determine convenience by calculating risk scores related to worker motions. The aim of REBA and RULA risk assessment methods is to study whether or not the worker is functioning in accordance with his/her skills and to prevent labor accidents and occupational diseases with the help of the data obtained. In this study, REBA and RULA risk scores are tried to be calculated by studying the motions of apparel workshop employees working in the fabric cutting, quality, packaging, ironing and stain removal sections. According to the analysis obtained, REBA score for the fabric cutting employee is 6, RULA score for the sewing machine operator is 4, REBA score for the quality control employee is 4, REBA score for the stain removal employee is 3, REBA score for the ironing employee is 6 and REBA score for the packaging employee is 5. According to the scores obtained through the use of REBA and RULA risk assessment method, the motions and postures of employees are determined to be at dangerous levels. Among the primary precautions needed to be taken to prevent the risks can be having the employee work at different tasks within certain intervals, monitoring the health, providing occupational health and safety educational programs

Objective To evaluate the 6 months efficacy and safety of cyanoacrylate closure for the treatment of incompetent great saphenous veins (GSVs) in comparison with radiofrequency ablation (RFA). Methods In this multicenter, retrospective, clinical trial, 398 symptomatic subjects with incompetent GSVs were assigned to either cyanoacrylate closure or RFA. The primary endpoint, complete closure of the target GSV, was determined using duplex ultrasound examination starting from one-, three-, and six-month visits. Results All patients were followed for 6 months and there was no difference between the groups in terms of mean follow-up time. Hospital stay and return to work/activity were shorter in the cyanoacrylate ablation (CAA) group, and these differences between the groups were statistically significant. Ecchymosis was observed higher in the RFA group and was statistically significant. Conclusions In this study, in which we examined the CAA and RFA methods, we found that both methods were effective and reliable; however, we found that patients in the CAA group had a more comfortable postoperative period and returned to work earlier.

Workplaces are divided into three as very dangerous, dangerous and less dangerous according to the principle of the work done. When occupational accidents and diseases are mentioned, construction sites and mines are considered. However, although the probability of occupational accidents and diseases is low, most working areas throughout the country are offices. In the offices, there are obligations that the employer must fulfill according to the law numbered 6331. Employees in offices that accommodate employees from all levels of the public and private sector are likely to be exposed to risk factors. Office workers are most exposed to physical, psychosocial and ergonomic risk factors. The employer is likely to prevent work accidents and occupational diseases by providing a healthy and safe working environment for its employees. In this study, a questionnaire consisting of 28 questions was applied to examine the perception levels of physical, psychosocial and ergonomic risk factors for 246 office workers in public and private sector institutions in Samsun. The answers to the questionnaire questions were analyzed with the program "IBM SPSS Statistics 22.0" and the value of "Cronbach Alpha (α)" was found to be 0.667. The fact that α value is in the range of 0.6

Objectives: The coronary endarterectomy combined with coronary artery bypass grafting (CABG) is an useful but still controversial surgical technique in diffuse coronary artery disease. The aim of this study was to analyze the operative and early postoperative outcomes of the patients who underwent CABG with and without coronary endarterectomy. Methods: This retrospective study included a total of 312 consequtive patients undergoing on-pump CABG from December 2018 to December 2020 in the Department of Cardiovascular Surgery, Bursa Yüksek İhtisas Training and Research Hospital. Patients were divided into 2 groups as those who underwent coronary endarterectomy combined with on-pump CABG (Group 1, n = 48) and those who underwent isolated on-pump CABG (Group 2, n = 264). Peroperative variables were obtained from our hospital's computerized database and retrospectively analyzed. Results: Previous percutaneus coronary intervention rate and the number of patients with diabetes mellitus was significantly higher in the endarterectomy group. The demographics and characteristics of the patients were similar between the two groups. The median number of distal anastomoses was 4 (2-5) in Group 1 and 2 (1-5) in Group 2. Median cross-clamp duration and perfusion times in Group 1 were longer than Group 2 (82 min vs. 63 min; p < 0.001 and 120 min vs. 95 min; p = 0.003, respectively). A total of 54 coronary endarterectomy practices were performed on 48 patients, and the LAD artery (73%) was the most endarterectomized vessel. In Group 1, postoperative 24 hours high-sensitive troponin I levels were significantly higher than in Group 2 (p < 0.001). There was no significant difference between the groups in terms of operative mortality, low cardiac output rates and perioperative myocardial infarction rates. Postoperative atrial fibrillation was significantly higher in Group 1 (p = 0.023). Conclusions: Although coronary endarterectomy is a complex procedure, in patients with diffuse coronary artery disease, it is an essential and sometimes mandotary method in order to achieve complete revacularization and can be performed safely with acceptable operative and early postoperative outcomes.

Objective: To investigate the relationship between prognostic nutritional index (PNI) and carotid artery stenosis (CAS). Material and Methods: This retrospective observational study included patients undergoing carotid endarterectomy (CEA) and patients with non-critical CAS who received medical treatment. All data retrieved retrospectively from the hospital medical files. The values acquired from the patients during acceptance to the hospital were used in the calculation of PNI. Results: There were 82 patients (68.3 % male, mean age: 70.5±8.9 years) in surgical group, and 79 patients (72.2% male, mean age: 62.0±9.1 years) were recorded in medical group. We detected statistically difference in surgical group in terms of higher BUN (p

Vitamin D is an important vitamin that has hormone-like effects in the human body. 1,25-dihydroxy vitamin D (1,25(OH)2 D) is known as the active form of vitamin D. Activated vitamin D can affect cellular proliferation, apoptosis, cellular membrane transport, immune system, and aging through genes. Postoperative atrial fibrillation (PoAF) is an important problem that increases mortality and morbidity rates after cardiac surgery operations. Various studies have been conducted on the relationship between vitamin D and PoAF. Although there are studies in the literature showing that vitamin D supplementation reduces cardiovascular mortality and morbidity in different study types (randomized vs. observational), there are also studies showing that it has no effect on clinical outcomes. Since the subject is atrial fibrillation, the conditions of the study groups such as age, the prevalence of coronary artery disease, degree of hypertension, and lung disease should be analyzed well. On the other hand, vitamin D supplementation should be carefully determined for which patient, for how long, and at what dose.

Peripheral artery disease (PAD) is a common disease among women and is expected to increase in the coming years. Diagnostic and therapeutic management of PAD in women is difficult due to their gender-related differences, comorbid factors, atypical symptoms, more functional disorders, the presence of advanced disease, being older age of the disease onset, smaller vessel diameter, and psychosocial factors. Especially due to the high prevalence of asymptomatic disease, late admission status and further disease on admission affect the success of the treatment negatively. By focusing more on PAD in women and more clinical studies, gender-specific differences can be identified. Hereby, there is a need to develop appropriate strategies to improve women's overall quality of life. In this review, we aimed to draw attention to the female gender with PAD, which is increasingly occurring.

Objectives: Serious complications are seen after cardiac surgery operations. Postoperative pneumonia is one of the most important of these complications. Some biomarkers have been examined in the prediction of mortality in special groups such as hospital-acquired pneumonia or aspiration pneumonia. In addition to parameters such as blood-urea nitrogen and albumin, the blood urea nitrogen to albumin ratio obtained by the ratio of these two parameters is also used as a mortality predictor. In this study, it was aimed to investigate the effect of the blood urea nitrogen to albumin ratio at the time of diagnosis of pneumonia on mortality in patients who developed pneumonia in the early period after cardiac surgery. Methods: In this study, 138 patients who developed pneumonia in the early period after cardiac surgery were examined. Complete blood count and biochemical test results were analyzed for all patients, and differences between groups were investigated. The patients who developed in-hospital pneumonia and were discharged as survivors were classified as Group 1, and non-survivor patients were determined as Group 2. Results: Patients who did not develop in-hospital mortality were included in Group 1 (n = 105, mean age = 63.7 ± 9.2 years), and those with non-survivor were included in Group 2 (n = 33, mean age = 66.9 ± 9.6 years). At the time of diagnosis neutrophil-lymphocyte ratio, C-reactive protein, blood-urea nitrogen and blood urea nitrogen to albumin ratio values were significantly higher in Group 2 (p < 0.001, p < 0.001, p = 0.004 and p < 0.001; respectively) ROC curve analysis was performed to evaluate blood urea nitrogen to albumin ratio in predicting mortality. The cut-off value of blood urea nitrogen to albumin ratio was 4.1 (Area under the curve [AUC]: 0.740, 95% CI: 0.690-0.820, p < 0.001, with sensitivity of 72.5% and specificity of 68.6%). Conclusions: In pneumonia developing after cardiac surgery, we found that the peripheral blood blood urea nitrogen to albumin ratio at the time of the first symptom in the patient has a high predictive power for the development of mortality in this particular patient group.

Objectives: It has been stated in various studies that there is a difference in some blood parameters between hypertensive and normotensive patients for a long time. Mean platelet volume (MPV), and red blood cell distribution width (RDW), have been studied in hypertensive patient groups in many studies. Hypertension is a classic risk factor for ischemic stroke and myocardial ischemia, as known. In our study, we examined whether there was a difference between hypertensive patient groups and normotensive patients in terms of blood parameters such as MPV and RDW, and the incidence of stroke and myocardial infarction. Methods: Blood samples and twenty-four-hour ambulatory blood pressure monitoring (ABPM) results of 552 patients admitted to our outpatient clinic with a pre-diagnosis of hypertension were retrospectively analyzed. According to ABPM results, we divided the study participants into four groups; dippers, non-dippers, extreme dippers, and normotansives. Complete blood count and biochemical test results were found in the database of our hospital for all patients and differences between groups were investigated. Results: One hundred seventy three normotensives (Group 1) (mean age, 47.4 ± 15.4 years), 210 non-dippers (Group 2) (mean age, 53.8 ± 15.8 years), 67 extreme dippers (Group 3) (mean age, 49.1 ± 15.9 years) and 102 dippers (Group 4) (mean age, 52.2 ± 12.5 years). Daytime mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) and night-time mean SBP and DBP were significantly different in groups (Group 1: 117 [90-193] mmHg and 71 [55-87] mmHg; Group 2: 137 [107-188] mmHg and 83 [107-188] mmHg; Group 3: 143 [115-193] mmHg and 88 [56-122] mmHg; and Group 4: 140.5 [116-173] mmHg and 76 [55-124] mmHg), p < 0.001; respectively. MPV and RDW levels were different in all four groups (p < 0.001). We found a significant difference in the rates of stroke and coronary artery disease between the four groups (p = 0.018 and p = 0.002, respectively). In the ROC curve analysis MPV had sensitivity of %77. 8 and specificity of 78. 1% for stroke when the cut-off value MPV was 9.25 (Area under curve: 0.808, 95% confidence interval: 0.726-0.889, p < 0.001). Conclusions: In our study, MPV and RDW levels and the rates of stroke and cardiovascular disease were significantly higher in non-dipper patients compared to other groups.

Background Acute limb ischemia (ALI) is an emergency vascular pathology in which perfusion is disrupted in the lower extremity and threatens extremity viability. The admission blood glucose (ABG)/estimated average glucose (eAG) value has recently been shown as a prognostic marker in acute cardiovascular events. In this study, we aimed to investigate the predictive role of an ABG/eAG value in predicting development of early postoperative major amputation after emergency thromboembolectomy operations in patients presenting with ALI. Method Patients who admitted to our hospital with ALI between November 01, 2016 and September 01, 2021 and underwent surgical thromboembolectomy were retrospectively included in the study. Patients who did not undergo postoperative limb amputation were recorded as Group 1, and patients who underwent major amputation in the early postoperative period (in-hospital), were recorded as Group 2. Results The median age of the 226 patients included in Group 1 and 72 patients in Group 2 were 58 (34–86) years and 69 (33–91) years, respectively ( p70 years (odds ratio [OR]: 1.914, 95% confidence interval [CI]: 1.351–2.319, p6 h (OR: 1.770, 95% CI: 1.480–1.152, p = 0.009), ABG (OR: 1.275, 95% CI: 1.050–1.790, p < 0.001), and ABG/eAG (OR: 1.669, 95% CI: 1.315–2.239, p < 0.001). Conclusion According to our study, we can predict patient groups with a high risk of major amputation with the ABG/eAG value calculated from the blood values of the patients at the time of admission.

Acute type A aortic dissection is a life-threatening disease associated with high morbidity and mortality that requires urgent surgical intervention. Hemodilution is inevitable in cardiac operations performed with cardiopulmonary bypass, which leads to nadir hematocrit levels. Studies have shown that nadir hematocrit levels are associated with poor postoperative outcomes. The management strategy of intraoperative anemia in these operations is still controversial. Should we follow the patients with intraoperative low hematocrit values or should we transfuse them? In addition to intraoperative nadir hematocrit, cannulation strategies play an important role in early postoperative outcomes after aortic dissection surgery.