Search

Poly(ethylene oxide) (PEO) is a well-known biocompatible polymer and has widely been used for medical applications. Recently, we have investigated the dynamic behavior of hydration water in the vicinity of PEO chains at physiological temperature and shown the presence of slow water with diffusion coefficient one order of magnitude less than that of bulk water. This could be evidence for the intermediate water that is critical for biocompatibility; however, its detailed dynamical features were not established. In this article, we analyze the quasi-elastic neutron scattering from hydration water through mode distribution analysis and present a microscopic picture of hydration water as well as its relation to cold crystallization. [ABSTRACT FROM AUTHOR]

We report a two-stage crash process in edge localized mode (ELM) driven by resistive drift-ballooning modes (RDBMs) numerically simulated in a full annular torus domain with a scale-separated four-field reduced MHD (RMHD) model using the BOUT++ framework. In the early nonlinear phase, the small first crash is triggered by linearly unstable RDBMs, and m / n = 2 / 1 magnetic islands are nonlinearly excited by nonlinear coupling of RDBMs as well as their higher harmonics. Here, m is the poloidal mode number, n is the toroidal mode number, the q = 2 rational surface exists near the pressure gradient peak, and q is the safety factor. Simultaneously, middle-n RDBM turbulence develops but is poloidally localized around X-points of the magnetic islands, leading to the small energy loss. The second large crash occurs in the late nonlinear phase. Higher harmonics of m / n = 2 / 1 magnetic islands well develop around the q = 2 surface via nonlinear coupling and make the magnetic field stochastic by magnetic island overlapping. Turbulence heat transport develops at X-points of higher harmonics of m / n = 2 / 1 magnetic islands, resulting in the turbulence spreading in the poloidal direction. The large second crash is triggered when the turbulence covers the whole poloidal region so that the magnetic island generation and magnetic field stochastization before the large crash can be interpreted as ELM precursors. It is concluded that the ELM trigger is attributed to the turbulent spreading in the poloidal direction in synchronization with the magnetic field stochastization and the crash is driven by E × B convection rather than the conventional Rechester–Rosenbluth anomalous electron heat transport. [ABSTRACT FROM AUTHOR]

The Japan Anti-Doping Agency established a certification system of sports pharmacist (hereafter, SP) in 2009, which certifies pharmacists as professionals with the most up-to-date information on anti-doping guidelines. Despite the fact that the number of certified SP is increasing, few studies examined awareness of SP or the usefulness of SP for athletes and individuals involved in sports. This study used a snowball sampling survey to identify sports trainers' current awareness for SP in connection with their anti-doping activity. (Result) Of the respondents, 51.0% had experienced related to anti-doping activity, and 87.8% had experience of receive a question in regard to health problems from athletes. The recognition rate of SP was 85.8%, and high expectation of expertise among SP in terms of anti-doping knowledge for medications and nutritional supplements was revealed. Trainers seek easy access to SP consultation, as well as face-to-face communication. (Conclusion) This study revealed that trainers were involved in health consultations from athletes and anti-doping activity. The recognition rate of SP and expectations of them were high. For more effective usage of SP, accessibility to them should be improved and direct relationships between trainers and SP need to be built. [ABSTRACT FROM AUTHOR]

Shear-induced multilamellar vesicle (MLV) formation has been studied by coupling the small-angle neutron scattering (SANS) technique with neutron spin echo (NSE) spectroscopy.A10%mass fraction of the nonionic surfactant pentaethylene glycol dodecyl ether (C12E5) inwaterwas selected as a model system for studying weak inter-lamellar interactions. These interactions are controlled either by adding an anionic surfactant, sodium dodecyl sulfate, or an antagonistic salt, rubidium tetraphenylborate. Increasing the charge density in the bilayer induces an enhanced ordering of the lamellar structure. The charge density dependence of the membrane bending modulus was determined by NSE and showed an increasing trend with charge. This behavior is well explained by a classical theoretical model. By considering the Caillé parameters calculated from the SANS data, the layer compressibility modulus ... is estimated and the nature of the dominant inter-lamellar interaction is determined. Shear flow induces MLV formation around a shear rate of 10 s-1, when a small amount of charge is included in the membrane. The flow-induced layer undulations are in-phase between neighboring layers when the inter-lamellar interaction is sufficiently strong. Under these conditions, MLV formation can occur without significantly changing the inter-lamellar spacing. On the other hand, in the case of weak interlamellar interactions, the flow-induced undulations are not in-phase, and greater steric repulsion leads to an increase in the inter-lamellar spacing with shear rate. In this case, MLV formation occurs as the amplitude of the undulations gets larger and the steric interaction leads to in-phase undulations between neighboring membranes. [ABSTRACT FROM AUTHOR]