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Organisms often swim through fluids that are spatially inhomogeneous. If the fluids are polymeric, gradients in polymer concentration may lead to gradients in both fluid viscosity and elasticity. In this letter, we present theoretical results for the dynamics of active particles, biological or otherwise, swimming through spatially inhomogeneous viscoelastic fluids. We model the active particles using the squirmer model, and show that spatial variations in fluid relaxation time lead to a novel mechanism for reorientation and taxis in viscoelastic fluids, which we refer to as a form of durotaxis in fluids., Comment: 5 pages, 1 figure

Text generation is the automated process of producing written or spoken language using computational methods. It involves generating coherent and contextually relevant text based on predefined rules or learned patterns. However, challenges in text generation arise from maintaining coherence, ensuring diversity and creativity, and avoiding biases or inappropriate content. This research paper developed a novel approach to improve text generation in the context of joint Natural Language Generation (NLG) and Natural Language Understanding (NLU) learning. The data is prepared by gathering and preprocessing annotated datasets, including cleaning, tokenization, stemming, and stop-word removal. Feature extraction techniques such as POS tagging, Bag of words, and Term Frequency-Inverse Document Frequency (TF-IDF) are applied. Transformer-based encoders and decoders, capturing long range dependencies and improving source-target sequence modelling. Pre-trained language models like Optimized BERT are incorporated, along with a Hybrid Redfox Artificial Hummingbird Algorithm (HRAHA). Reinforcement learning with policy gradient techniques, semi-supervised training, improved attention mechanisms, and differentiable approximations like straight-through Gumbel SoftMax estimator are employed to fine-tune the models and handle complex linguistic tasks effectively. The proposed model is implemented using Python.

Despite the significance of coronal mass ejections (CMEs) in space weather, a comprehensive understanding of their interior morphology remains a scientific challenge, particularly with the advent of many state-of-the-art solar missions such as Parker Solar Probe (Parker) and Solar Orbiter (SO). In this study, we present an analysis of a complex CME as observed by the Wide-Field Imager for Solar PRobe (WISPR) heliospheric imager during Parker's seventh solar encounter. The CME morphology does not fully conform with the general three-part density structure, exhibiting a front and core not significantly bright, with a highly structured overall configuration. In particular, its morphology reveals non-concentric nested rings, which we argue are a signature of the embedded helical magnetic flux rope (MFR) of the CME. For that, we analyze the morphological and kinematical properties of the nested density structures and demonstrate that they outline the projection of the three-dimensional structure of the flux rope as it crosses the lines of sight of the WISPR imager, thereby revealing the magnetic field geometry. Comparison of observations from various viewpoints suggests that the CME substructures can be discerned owing to the ideal viewing perspective, close proximity, and spatial resolution of the observing instrument., Comment: 21 pages, 11 figures

Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial impact on the success of IVF. The assessment of sperm DNA is traditionally done through chemical assays which render sperm cells ineligible for IVF. Many compounding factors lead to the population crisis, with fertility rates dropping globally in recent history. As such assisted reproductive technologies (ART) have been the focus of recent research efforts. Simultaneously, artificial intelligence has grown ubiquitous and is permeating more aspects of modern life. With the advent of state-of-the-art machine learning and its exceptional performance in many sectors, this work builds on these successes and proposes a novel framework for the prediction of sperm cell DNA fragmentation from images of unstained sperm. Rendering a predictive model which preserves sperm integrity and allows for optimal selection of sperm for IVF.

The ICPR 2024 Competition on Safe Segmentation of Drive Scenes in Unstructured Traffic and Adverse Weather Conditions served as a rigorous platform to evaluate and benchmark state-of-the-art semantic segmentation models under challenging conditions for autonomous driving. Over several months, participants were provided with the IDD-AW dataset, consisting of 5000 high-quality RGB-NIR image pairs, each annotated at the pixel level and captured under adverse weather conditions such as rain, fog, low light, and snow. A key aspect of the competition was the use and improvement of the Safe mean Intersection over Union (Safe mIoU) metric, designed to penalize unsafe incorrect predictions that could be overlooked by traditional mIoU. This innovative metric emphasized the importance of safety in developing autonomous driving systems. The competition showed significant advancements in the field, with participants demonstrating models that excelled in semantic segmentation and prioritized safety and robustness in unstructured and adverse conditions. The results of the competition set new benchmarks in the domain, highlighting the critical role of safety in deploying autonomous vehicles in real-world scenarios. The contributions from this competition are expected to drive further innovation in autonomous driving technology, addressing the critical challenges of operating in diverse and unpredictable environments., Comment: 15 pages, 7 figures, ICPR Competition Paper

In recent times a number of platforms are using badge-based achievements or leaderboards to increase user involvement and participation. Due to recent advancements, there is a question of up to what extent virtual achievement systems have on users using particular platforms. Here in this paper, we discuss measuring the impact of the leaderboard-based achievement system by integrating it into an online learning android application UPSC Pre that has thousands of questions and answers categorized topic wise related to UPSC exams, one of the toughest exams to crack in the world. We are conducting the experiment on 10 randomly chosen students who are using the app in a controlled setting and the data measurement is done using the Firebase Analytics tool by Google. We observed that the students using the leaderboard have increased participation without any reductions in their quality and the time of using the platform has increased compared to previous engagements. Students who participated in the experiment felt the leaderboard was competitive and enjoyed gaining positions on the leaderboard and wanted it in the User interface for other platforms as well. The research has an impact in designing the learning applications to cater and improve the user experience in the future. The results are not limited to educational purposes but can be expanded to other fields such as self development applications, other research projects, Gaming industry and many more., Comment: 4 Pages, 4 Figures

Quantum computing (QC) provides a promising avenue toward enabling quantum chemistry calculations, which are classically impossible due to a computational complexity that increases exponentially with system size. As fully fault-tolerant algorithms and hardware, for which an exponential speedup is predicted, are currently out of reach, recent research efforts are dedicated to developing and scaling algorithms for Noisy Intermediate-Scale Quantum (NISQ) devices to showcase the practical utility of such machines. To demonstrate the utility of NISQ devices in the field of chemistry, we apply our recently developed FAST-VQE algorithm and a novel quantum gate reduction strategy based on propositional satisfiability together with standard optimization tools for the simulation of the rate-determining proton transfer step for CO2 hydration catalysed by carbonic anhydrase resulting in the first application of a quantum computing device for the simulation of an enzymatic reaction. To this end, we have combined classical force field simulations with quantum mechanical methods on classical and quantum computers in a hybrid calculation approach. The presented technique significantly enhances the accuracy and capabilities of QC-based molecular modeling and finally pushes it into compelling and realistic applications. The framework is general and can be applied beyond the case of computational enzymology.

CNOT optimization plays a significant role in noise reduction for Quantum Circuits. Several heuristic and exact approaches exist for CNOT optimization. In this paper, we investigate more complicated variations of optimal synthesis by allowing qubit permutations and handling layout restrictions. We encode such problems into Planning, SAT, and QBF. We provide optimization for both CNOT gate count and circuit depth. For experimental evaluation, we consider standard T-gate optimized benchmarks and optimize CNOT sub-circuits. We show that allowing qubit permutations can further reduce up to 56% in CNOT count and 46% in circuit depth. In the case of optimally mapped circuits under layout restrictions, we observe a reduction up to 17% CNOT count and 19% CNOT depth., Comment: 9 pages, 12 tables

Schizophrenia (SZ) is a severe brain disorder marked by diverse cognitive impairments, abnormalities in brain structure, function, and genetic factors. Its complex symptoms and overlap with other psychiatric conditions challenge traditional diagnostic methods, necessitating advanced systems to improve precision. Existing research studies have mostly focused on imaging data, such as structural and functional MRI, for SZ diagnosis. There has been less focus on the integration of genomic features despite their potential in identifying heritable SZ traits. In this study, we introduce a Multi-modal Imaging Genomics Transformer (MIGTrans), that attentively integrates genomics with structural and functional imaging data to capture SZ-related neuroanatomical and connectome abnormalities. MIGTrans demonstrated improved SZ classification performance with an accuracy of 86.05% (+/- 0.02), offering clear interpretations and identifying significant genomic locations and brain morphological/connectivity patterns associated with SZ., Comment: Accepted for presentation at the AI for Imaging Genomic Learning (AIIG) Workshop, MICCAI 2024

Schizophrenia (SZ) is a complex mental disorder that necessitates accurate and timely diagnosis for effective treatment. Traditional methods for SZ classification often struggle to capture transient EEG features and face high computational complexity. This study proposes a convolutional autoencoder (CAE) to address these challenges by reducing dimensionality and computational complexity. Additionally, we introduce a novel approach utilizing spectral scalograms (SS) combined with EfficientNet (ENB) architectures. The SS, obtained through continuous wavelet transform, reveals temporal and spectral information of EEG signals, aiding in the identification of transient features. ENB models, through transfer learning (TL), extract discriminative features and improve SZ classification accuracy. Experimental evaluation on a comprehensive dataset demonstrates the efficacy of our approach, achieving a five-fold mean cross-validation accuracy of 98.5\% using CAE with a soft voting classifier and 99\% employing SS with the ENB7 model. These results suggest the potential of our methods to enhance SZ diagnosis, surpassing traditional deep learning (DL) and TL techniques. By leveraging CAE and ENBs, this research offers a robust framework for objective SZ classification, promoting early intervention and improved patient outcomes.

We present the identification and physical analysis of a possible magnetic island feature seen in white-light images observed by the Wide-field Imager for Solar Probe (WISPR) on board the Parker Solar Probe (Parker). The island is imaged by WISPR during Parker's second solar encounter on 2019 April 06, when Parker was ~38 solar radii from the Sun center. We report that the average velocity and acceleration of the feature are approximately 334 km s and -0.64 m s-2. The kinematics of the island feature, coupled with its direction of propagation, indicate that the island is likely entrained in the slow solar wind. The island is elliptical in shape with a density deficit in its center, suggesting the presence of a magnetic guide field. We argue that this feature is consistent with the formation of this island via reconnection in the current sheet of the streamer. The feature's aspect ratio (calculated as the ratio of its minor to major axis) evolves from an elliptical to a more circular shape that approximately doubles during its propagation through WISPR's field of view. The island is not distinct in other white-light observations from the Solar and Heliospheric Observatory (SOHO) and the Solar Terrestrial Relations Observatory (STEREO) coronagraphs, suggesting that this is a comparatively faint heliospheric feature and that viewing perspective and WISPR's enhanced sensitivity are key to observing the magnetic island.

We find the mixing induced by a small swimming organism in a density stratified fluid. We model the swimmer as a spherical squirmer and quantify mixing through a mixing efficiency that is the ratio of rate of change of potential energy of fluid to the total work done by the swimmer. Assessing mixing in the near field and far field of the swimmer separately, we find that the near-field mixing aligns with past work, but the overall mixing is much larger than that caused by a point-sized swimmer (like force-dipole), although still small in weak stratification. Equivalent results are also obtained for a homogeneous dilute suspension of non-interacting swimmers. Our study highlights the impact of swimmer size on mixing, revealing that small-sized swimmers cannot induce substantial mixing. However, we propose few (unexplored) pathways through which small swimmers could induce significant mixing, ultimately contributing towards oceanic mixing., Comment: 11 pages

Automated retinal image medical description generation is crucial for streamlining medical diagnosis and treatment planning. Existing challenges include the reliance on learned retinal image representations, difficulties in handling multiple imaging modalities, and the lack of clinical context in visual representations. Addressing these issues, we propose the Multi-Modal Medical Transformer (M3T), a novel deep learning architecture that integrates visual representations with diagnostic keywords. Unlike previous studies focusing on specific aspects, our approach efficiently learns contextual information and semantics from both modalities, enabling the generation of precise and coherent medical descriptions for retinal images. Experimental studies on the DeepEyeNet dataset validate the success of M3T in meeting ophthalmologists' standards, demonstrating a substantial 13.5% improvement in BLEU@4 over the best-performing baseline model., Comment: This paper has been accepted for presentation at the IEEE International Conference on Image Processing (ICIP 2024)

Effectively representing medical images, especially retinal images, presents a considerable challenge due to variations in appearance, size, and contextual information of pathological signs called lesions. Precise discrimination of these lesions is crucial for diagnosing vision-threatening issues such as diabetic retinopathy. While visual attention-based neural networks have been introduced to learn spatial context and channel correlations from retinal images, they often fall short in capturing localized lesion context. Addressing this limitation, we propose a novel attention mechanism called Guided Context Gating, an unique approach that integrates Context Formulation, Channel Correlation, and Guided Gating to learn global context, spatial correlations, and localized lesion context. Our qualitative evaluation against existing attention mechanisms emphasize the superiority of Guided Context Gating in terms of explainability. Notably, experiments on the Zenodo-DR-7 dataset reveal a substantial 2.63% accuracy boost over advanced attention mechanisms & an impressive 6.53% improvement over the state-of-the-art Vision Transformer for assessing the severity grade of retinopathy, even with imbalanced and limited training samples for each class., Comment: This paper has been accepted for presentation at the IEEE International Conference on Image Processing (ICIP 2024)

Schizophrenia is a debilitating, chronic mental disorder that significantly impacts an individual's cognitive abilities, behavior, and social interactions. It is characterized by subtle morphological changes in the brain, particularly in the gray matter. These changes are often imperceptible through manual observation, demanding an automated approach to diagnosis. This study introduces a deep learning methodology for the classification of individuals with Schizophrenia. We achieve this by implementing a diversified attention mechanism known as Spatial Sequence Attention (SSA) which is designed to extract and emphasize significant feature representations from structural MRI (sMRI). Initially, we employ the transfer learning paradigm by leveraging pre-trained DenseNet to extract initial feature maps from the final convolutional block which contains morphological alterations associated with Schizophrenia. These features are further processed by the proposed SSA to capture and emphasize intricate spatial interactions and relationships across volumes within the brain. Our experimental studies conducted on a clinical dataset have revealed that the proposed attention mechanism outperforms the existing Squeeze & Excitation Network for Schizophrenia classification., Comment: This paper has been accepted for the 21st IEEE International Symposium on Biomedical Imaging (ISBI 2024)

Despite advancements in medical care, hip fractures impose a significant burden on individuals and healthcare systems. This paper focuses on the prediction of hip fracture risk in older and middle-aged adults, where falls and compromised bone quality are predominant factors. We propose a novel staged model that combines advanced imaging and clinical data to improve predictive performance. By using CNNs to extract features from hip DXA images, along with clinical variables, shape measurements, and texture features, our method provides a comprehensive framework for assessing fracture risk. A staged machine learning-based model was developed using two ensemble models: Ensemble 1 (clinical variables only) and Ensemble 2 (clinical variables and DXA imaging features). This staged approach used uncertainty quantification from Ensemble 1 to decide if DXA features are necessary for further prediction. Ensemble 2 exhibited the highest performance, achieving an AUC of 0.9541, an accuracy of 0.9195, a sensitivity of 0.8078, and a specificity of 0.9427. The staged model also performed well, with an AUC of 0.8486, an accuracy of 0.8611, a sensitivity of 0.5578, and a specificity of 0.9249, outperforming Ensemble 1, which had an AUC of 0.5549, an accuracy of 0.7239, a sensitivity of 0.1956, and a specificity of 0.8343. Furthermore, the staged model suggested that 54.49% of patients did not require DXA scanning. It effectively balanced accuracy and specificity, offering a robust solution when DXA data acquisition is not always feasible. Statistical tests confirmed significant differences between the models, highlighting the advantages of the advanced modeling strategies. Our staged approach could identify individuals at risk with a high accuracy but reduce the unnecessary DXA scanning. It has great promise to guide interventions to prevent hip fractures with reduced cost and radiation., Comment: 29 pages, 5 figures, 6 tables

Relativistic discrete ejecta launched by black hole X-ray binaries (BH XRBs) can be observed to propagate up to parsec-scales from the central object. Observing the final deceleration phase of these jets is crucial to estimate their physical parameters and to reconstruct their full trajectory, with implications for the jet powering mechanism, composition and formation. In this paper we present the results of the modelling of the motion of the ejecta from three BH XRBs: MAXI J1820+070, MAXI J1535$-$571 and XTE J1752$-$223, for which high-resolution radio and X-ray observations of jets propagating up to $\sim$15 arcsec ($\sim$0.6 pc at 3 kpc) from the core have been published in the recent years. For each jet, we modeled its entire motion with a dynamical blast-wave model, inferring robust values for the jet Lorentz factor, inclination angle and ejection time. Under several assumptions associated to the ejection duration, the jet opening angle and the available accretion power, we are able to derive stringent constraints on the maximum jet kinetic energy for each source (between $10^{43}$ and $10^{44}$ erg, including also H1743$-$322), as well as placing interesting upper limits on the density of the ISM through which the jets are propagating (from $n_{\rm ISM} \lesssim 0.4$ cm$^{-3}$ down to $n_{\rm ISM} \lesssim 10^{-4}$ cm$^{-3}$). Overall, our results highlight the potential of applying models derived from gamma-ray bursts to the physics of jets from BH XRBs and support the emerging picture of these sources as preferentially embedded in low-density environments., Comment: 22 pages, 9 figures. Accepted for publication in MNRAS

In this paper, we explore the potential application of Large Language Models (LLMs) that will automatically model constraints and generate code for dynamic scheduling problems given an existing static model. Static scheduling problems are modelled and coded by optimization experts. These models may be easily obsoleted as the underlying constraints may need to be fine-tuned in order to reflect changes in the scheduling rules. Furthermore, it may be necessary to turn a static model into a dynamic one in order to cope with disturbances in the environment. In this paper, we propose a Retrieval-Augmented Generation (RAG) based LLM model to automate the process of implementing constraints for Dynamic Scheduling (RAGDyS), without seeking help from an optimization modeling expert. Our framework aims to minimize technical complexities related to mathematical modelling and computational workload for end-users, thereby allowing end-users to quickly obtain a new schedule close to the original schedule with changes reflected by natural language constraint descriptions., Comment: 7 pages (excluding appendix), 10 figures, 3 tables

Out-of-system (OoS) interference is a potential limitation for distributed networks that operate in unlicensed spectrum or in a spectrum sharing scenario. The OoS interference differs from the in-system interference in that OoS signals and their associated channels (or even their statistics) are completely unknown. In this paper, we propose a novel distributed algorithm that can mitigate OoS interference in the uplink and suppress the signal transmission in the OoS direction in the downlink. To estimate the OoS interference, each access point (AP), upon receiving an estimate of OoS interference from a previous AP, computes a better estimate of OoS interference by rotate-and-average using Procrustes method and forwards the estimates to the next AP. This process continues until the central processing unit (CPU) receives the final estimate. Our method has comparable performance to that of a fully centralized interference rejection combining algorithm and has much lower fronthaul load requirements., Comment: 5 pages, 2 figures, to be published in IEEE Wireless Communications Letters

In this note, we study the effect of viscosity gradients on the energy dissipated by the motion of microswimmers and the associated efficiency of that motion. Using spheroidal squirmer model swimmers in weak linearly varying viscosity fields, we find that efficiency depends on whether they generate propulsion from the back (pushers) or the front (pullers). Pushers are faster and more efficient when moving down gradients but slower and less efficient moving up viscosity gradients, and the opposite is true for pullers. However, both pushers and pullers display negative viscotaxis, therefore pushers dynamically tend to the most efficient orientation while pullers the least. We also evaluate the effect of shape on power expenditure and efficiency when swimming in viscosity gradients and find that in general the change in both due to gradients monotonically decreases with increasing slenderness. This work shows how shape and gait play an important role in determining dynamics and efficiency in inhomogeneous environments, and demonstrating that both efficiency minimizing and maximizing stable dynamical states are possible., Comment: 12 pages, 1 figure

The growing prominence of large language models (LLMs) necessitates the exploration of their capabilities beyond English. This research investigates the Telugu language proficiency of ChatGPT and Gemini, two leading LLMs. Through a designed set of 20 questions encompassing greetings, grammar, vocabulary, common phrases, task completion, and situational reasoning, the study delves into their strengths and weaknesses in handling Telugu. The analysis aims to identify the LLM that demonstrates a deeper understanding of Telugu grammatical structures, possesses a broader vocabulary, and exhibits superior performance in tasks like writing and reasoning. By comparing their ability to comprehend and use everyday Telugu expressions, the research sheds light on their suitability for real-world language interaction. Furthermore, the evaluation of adaptability and reasoning capabilities provides insights into how each LLM leverages Telugu to respond to dynamic situations. This comparative analysis contributes to the ongoing discussion on multilingual capabilities in AI and paves the way for future research in developing LLMs that can seamlessly integrate with Telugu-speaking communities.