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Your search keyword '"Shanmugasundaram, Olapalayam Lakshmanan"' showing total 3 results
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3 results on '"Shanmugasundaram, Olapalayam Lakshmanan"'

1. In vitro anti-inflammatory, anti-arthritic and anti- proliferative activity of green synthesized silver nanoparticles - Phoenix dactylifera (Rothan dates)

Author

Syed Zameer Ahmed Khader, Sidhra Syed Zameer Ahmed, Mohamed Rafi Mahboob, Selva Barathi Prabaharan, Shanmugasundaram Olapalayam Lakshmanan, Kishore Ramesh Kumar, and Daniel David

Subjects
Nanoparticles, Proliferation, Inflammatory, Arthritic, Green synthesis, Anticancer, Pharmacy and materia medica, RS1-441
Abstract

Abstract Traditionally dates is consumed as a rich source of iron supplement and the current research discuss the synthesis of silver nanoparticles (AgNPs) using methanolic seed extract of Rothan date and its application over in vitro anti-arthritic, anti-inflammatory and antiproliferative activity against lung cancer cell line (A549). FTIR result of synthesised AgNPs reveals the presence of functional group OH as capping agent. XRD pattern confirms the crystalline nature of the AgNPs with peaks at 38º, 44º, 64º and 81º, indexed by (111), (200), (220) and (222) in the 2θ range of 10-90, indicating the face centered cubic (fcc) structure of metallic Ag. HR- TEM results confirm the morphology of AgNPs as almost spherical with high surface areas and average size of 42 ± 9nm. EDX spectra confirmed that Ag is only the major element present and the Dynamic light scattering (DLS) assisted that the Z-average size was 203nm and 1.0 of PdI value. Zeta potential showed − 26.5mv with a single peak. The results of the biological activities of AgNPs exhibited dose dependent activity with 68.44% for arthritic, antiinflammatory with 63.32% inhibition and anti-proliferative activity illustrated IC50 value of 59.66 μg/mL expressing the potential of AgNPs to combat cancer.

Published
2022
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2. Influence of surfactants on structural, morphological, optical and antibacterial properties of SnO

Author

Sujatha, Karuppiah, Seethalakshmi, Thangaraj, Sudha, Arunachalam Palaniappan, and Shanmugasundaram, Olapalayam Lakshmanan

Subjects
Staphylococcus aureus, Surface-Active Agents, Molecular Structure, Escherichia coli, Metal Nanoparticles, Tin Compounds, Spectrophotometry, Ultraviolet, Microbial Sensitivity Tests, Crystallography, X-Ray, Anti-Bacterial Agents, Research Article
Abstract

Tin oxide (SnO(2)) nanoparticles were synthesised using various surfactants of different charges (n‐cetyl trimethyl ammonium bromide, sodium dodecyl sulphate and TRITON X‐100) by the co‐precipitation method. The synthesised nanomaterials were characterised using different techniques to study their structural, surface morphological, optical and anti‐bacterial activities. X‐ray diffraction patterns revealed the formation of a tetragonal rutile structure in pure and surfactants‐aided SnO(2) nanoparticles and the results show good agreement with JCPDS data [41‐1445]. The crystallite size of SnO(2) nanoparticles was found to decrease with the addition of surfactants. Scanning electron microscopy images exhibit spherical shape morphology with an average diameter of 30–75 nm for pure and surfactants‐aided SnO(2) nanoparticles. The band gap energy of the prepared materials was estimated from the UV–visible absorption spectra and a considerable increase in band gap energy was observed in surfactants‐aided SnO(2) nanoparticles (3.487, 3.57, 3.50 and 3.3 eV). The antibacterial activities of the synthesised nanoparticles were studied against Escherichia coli and Staphylococcus aureus bacteria.

Published
2019

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