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2,225 results on '"Shao, Tao"'

9. Robot-assisted thoracoscopic versus conventional thoracoscopic plication for diaphragmatic eventration in children: Comparison of mid-term outcomes

Author

Mengxin Zhang, Jingfeng Tang, Yuan Liu, Zhiqing Cao, Kangtai Wang, Guoqing Cao, Xi Zhang, and Shao-tao Tang

Subjects
Diaphragmatic eventration, Robot-assisted thoracoscopic plication, Conventional thoracoscopic plication, Pediatric, Pediatrics, RJ1-570, Surgery, RD1-811
Abstract

Objective: Minimally invasive surgery has been widely used for diaphragmatic eventration (DE). We aimed to compare the mid-term outcomes of robot-assisted thoracoscopic (RTP) and conventional thoracoscopic plication (CTP) for DE and to discuss the technical advantages of RTP. Methods: From January 2015 to July 2022, the clinical outcomes of 30 RTP patients and 35 CTP patients were retrospectively analyzed. The baseline data, surgical outcomes and surgical technique will be compared in detail. Results: The baseline data of two groups were comparable. No intraoperative conversion or complications occurred. The total operation time and intraoperative blood loss were similar between two groups, but RTP group had a significantly shorter diaphragmatic plication time compared to CTP group (25.77±3.55 min vs 44.49±4.43 min, p < 0.001). The total surgical cost of RTP group was higher than that of CTP group (48,593.06±2752.33 RMB vs 25,181.23±5681.51 RMB, p < 0.001). No significant differences were found in postoperative hospital stay, diclofenac suppository dosage, unplanned readmission rate within 30 days postoperatively, recurrence rate, or postoperative complications within 1 year postoperatively between RTP and CTP groups. Sixty patients had preoperative symptoms resolved or significantly improved with normal diaphragmatic position. However, two patients in CTP group encountered recurrence, and one patient in CTP group and two patients in RTP group had a diaphragm descent in only one intercostal space. Conclusion: RTP is a feasible and effective minimally invasive option for the treatment of DE, with mid-term outcomes comparable to CTP, which has a great advantage in terms of easier suturing and free knotting. DE can serve as an ideal disease type to train robots for thoracoscopic surgery by young doctors. Level of evidence: Level III.

Published
2024
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12. Robotic-assisted choledochal cyst excision with Roux-en-Y hepaticojejunostomy in children: A Chinese expert panel consensus statement

Author

Li, Shuai, Chung, Patrick HY, Gao, Zhigang, Xie, Xiaolong, Zhang, Hailan, Cao, Guoqing, Chen, Yajun, Duan, Xufei, Dong, Qi, Gu, Huajian, Luo, Yige, Li, Aiwu, Li, Shuixue, Li, Zhaozhu, Lin, Junshan, Liu, Dengrui, Liu, Haijin, Liu, Mingwei, Qu, Zhenfan, Su, Yi, Sun, Xiaobing, Xian, Hua, Xu, Di, Xu, Zhe, Zhang, Da, Bai, Yuzuo, Li, Suolin, Li, Long, Xiang, Bo, Wong, Kenneth Kak Yuen, and Tang, Shao-tao

Published
2024
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38. Current trends and prospects of surgical techniques for hepatoblastoma

Author

Jia‐rui Pu, Hang Li, Shuai Li, Yong Wang, Shi‐wang Li, and Shao‐tao Tang

Subjects
advances, hepatoblastoma, prospects, surgical technology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Hepatoblastoma, a common extracranial malignant solid tumor in childhood, is often detected at an advanced stage and is difficult to treat surgically. Despite the availability of multiple comprehensive treatments that can be combined with surgery, hepatoblastoma treatment outcomes remain poor. Surgery is the main treatment strategy for hepatoblastoma, but it faces many challenges, including tumor attachment to surrounding tissues, tumor wrapping or invading of vital organs and tissues, the presence of giant or multiple tumors, distant metastasis, the formation of a tumor thrombus, and significant surgical trauma. In this review, we discuss recent research advances and propose potential strategies for overcoming these challenges. Such strategies may improve the rate of hepatoblastoma resection and local control in children, as well as reduce complications and trauma.

Published
2024
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44. A 13-million turnover-number anionic Ir-catalyst for a selective industrial route to chiral nicotine

Author

Congcong Yin, Ya-Fei Jiang, Fanping Huang, Cong-Qiao Xu, Yingmin Pan, Shuang Gao, Gen-Qiang Chen, Xiaobing Ding, Shao-Tao Bai, Qiwei Lang, Jun Li, and Xumu Zhang

Subjects
Science
Abstract

Abstract Developing catalysts with both useful enantioselectivities and million turnover numbers (TONs) for asymmetric hydrogenation of ketones is attractive for industrial production of high-value bioactive chiral entities but remains a challenging. Herein, we report an ultra-efficient anionic Ir-catalyst integrated with the concept of multidentate ligation for asymmetric hydrogenation of ketones. Biocatalysis-like efficacy of up to 99% ee (enantiomeric excess), 13,425,000 TON (turnover number) and 224 s−1 TOF (turnover frequency) were documented for benchmark acetophenone. Up to 1,000,000 TON and 99% ee were achieved for challenging pyridyl alkyl ketone where at most 10,000 TONs are previously reported. The anionic Ir-catalyst showed a novel preferred ONa/MH instead of NNa/MH bifunctional mechanism. A selective industrial route to enantiopure nicotine has been established using this anionic Ir-catalyst for the key asymmetric hydrogenation step at 500 kg batch scale, providing 40 tons scale of product.

Published
2023
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