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28 results on '"Sheen, Maw-Chang"'

24. WOX1 Is Essential for UVB Irradiation–Induced Apoptosis and Down-Regulated via Translational Blockade in UVB-Induced Cutaneous Squamous Cell Carcinoma In vivo

Author

Lai, Feng-Jie, primary, Cheng, Ching-Li, additional, Chen, Shur-Tzu, additional, Wu, Chin-Han, additional, Hsu, Li-Jin, additional, Lee, J. Yu-Yun, additional, Chao, Sheau-Chiou, additional, Sheen, Maw-Chang, additional, Shen, Ching-Liang, additional, Chang, Nan-Shan, additional, and Sheu, Hamm-Ming, additional

Published
2005
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27. Effective eradication of oral verrucous carcinoma with continuous intraarterial infusion chemotherapy.

Author

Wu CF, Chen CM, Shen YS, Huang IY, Chen CH, Chen CY, Shieh TY, and Sheen MC

Subjects
Adult, Aged, Antimetabolites, Antineoplastic adverse effects, Carotid Artery, External, Catheters, Indwelling, Follow-Up Studies, Humans, Infusions, Intra-Arterial, Male, Methotrexate adverse effects, Middle Aged, Remission Induction, Antimetabolites, Antineoplastic administration & dosage, Carcinoma, Verrucous drug therapy, Methotrexate administration & dosage, Mouth Neoplasms drug therapy
Abstract

Background: We evaluated the effectiveness of intraarterial methotrexate infusion as a primary therapy for oral verrucous carcinoma (VC)., Methods: Fifteen male patients (mean age, 55 years) were included. By using an implantable port-catheter system and a portable pump, methotrexate was continuously infused to the external carotid artery for a mean period of 7.5 days (50 mg/day), followed by weekly bolus of methotrexate (25 mg) via intraarterial route for a mean period of 10 weeks., Results: The tumor regressed dramatically and disappeared completely after treatment within a mean period of 2.5 months. All patients obtained complete remission and recovered without disfigurement. All patients were alive without disease recurrence at a median follow-up of 43 months. The side effects were tolerable., Conclusions: The results of our treatment modality for oral VC appear to compete favorably with the results of surgical series and even more with those of radiotherapy series.

Published
2008
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28. Bile duct cancer 25 years after choledochoduodenostomy: a case report.

Author

Kuo KK, Sheen PC, Lee KT, Sheen MC, Chuang SC, Wang SR, and Wang WM

Subjects
Aged, Cholangitis complications, Humans, Male, Time Factors, Bile Duct Neoplasms etiology, Choledochostomy adverse effects
Abstract

We describe a 65-year-old man who had undergone choledochoduodenostomy (CDS) for choledocholithiasis 25 years prior to admission to our hospital for cholangitis. Abdominal sonography and computerized tomography (CT) scan revealed a tumor mass at the hilar region with bilateral intrahepatic duct dilatation. Upper gastrointestinal endoscopic examination indicated the site of the CDS. Biopsy was taken from the mucosa of the bile duct, and pathology revealed well-differentiated adenocarcinoma. CT scan and angiography further confirmed unresectable hilar bile duct cancer. Conservative treatment with intra-arterial chemotherapy was arranged. After briefly reviewing the hypothesized pathogenesis and radiographic diagnosis of this rare case, we recommend that chronic cholangitis consequent to CDS should be closely followed for late development of biliary tract malignancy.

Published
2002

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