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2. Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences

Author

Yu, Daqi, Ren, Yandong, Uesaka, Masahiro, Beavan, Alan J. S., Muffato, Matthieu, Shen, Jieyu, Li, Yongxin, Sato, Iori, Wan, Wenting, Clark, James W., Keating, Joseph N., Carlisle, Emily M., Dearden, Richard P., Giles, Sam, Randle, Emma, Sansom, Robert S., Feuda, Roberto, Fleming, James F., Sugahara, Fumiaki, Cummins, Carla, Patricio, Mateus, Akanni, Wasiu, D’Aniello, Salvatore, Bertolucci, Cristiano, Irie, Naoki, Alev, Cantas, Sheng, Guojun, de Mendoza, Alex, Maeso, Ignacio, Irimia, Manuel, Fromm, Bastian, Peterson, Kevin J., Das, Sabyasachi, Hirano, Masayuki, Rast, Jonathan P., Cooper, Max D., Paps, Jordi, Pisani, Davide, Kuratani, Shigeru, Martin, Fergal J., Wang, Wen, Donoghue, Philip C. J., Zhang, Yong E., and Pascual-Anaya, Juan

Published
2024
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4. Recent Advances in DNA‐Based Nanoprobes for In vivo MiRNA Imaging.

Author

Wang, Caixia, Song, Xuefang, Shen, Jieyu, Xie, Yuxin, Ju, Huangxian, and Liu, Ying

Subjects
GENE expression, MEMBRANE proteins, HAIRPIN (Genetics), ADENOSINE triphosphate, REGULATOR genes
Abstract

As a post transcriptional regulator of gene expression, microRNAs (miRNA) is closely related to many major human diseases, especially cancer. Therefore, its precise detection is very important for disease diagnosis and treatment. With the advancement of fluorescent dye and imaging technology, the focus has shifted from in vitro miRNA detection to in vivo miRNA imaging. This concept review summarizes signal amplification strategies including DNAzyme catalytic reaction, hybrid chain reaction (HCR), catalytic hairpin assembly (CHA) to enhance detection signal of lowly expressed miRNAs; external stimuli of ultraviolet (UV) light or near‐infrared region (NIR) light, and internal stimuli such as adenosine triphosphate (ATP), glutathione (GSH), protease and cell membrane protein to prevent nonspecific activation for the avoidance of false positive signal; and the development of fluorescent probes with emission in NIR for in vivo miRNA imaging; as well as rare earth nanoparticle based the second near‐infrared window (NIR‐II) nanoprobes with excellent tissue penetration and depth for in vivo miRNA imaging. The concept review also indicated current challenges for in vivo miRNA imaging including the dynamic monitoring of miRNA expression change and simultaneous in vivo imaging of multiple miRNAs. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences

Author

Pascual-Anaya, Juan, primary, Yu, Daqi, additional, Ren, Yandong, additional, Uesaka, Masahiro, additional, Beavan, Alan, additional, Muffato, Matthieu, additional, Shen, Jieyu, additional, Li, Yongxin, additional, Sato, Iori, additional, Wan, Wenting, additional, Clark, James, additional, Keating, Joseph, additional, Carlisle, Emily, additional, Dearden, Richard, additional, Giles, Sam, additional, Randle, Emma, additional, Sansom, Robert, additional, Feuda, Roberto, additional, Fleming, James, additional, Sugahara, Fumiaki, additional, Cummins, Carla, additional, Patricio, Mateus, additional, Akanni, Wasiu, additional, D'Aniello, Salvatore, additional, Bertolucci, Cristiano, additional, Irie, Naoki, additional, Alev, Cantas, additional, Sheng, Guojun, additional, de Mendoza, Alex, additional, Maeso, Ignacio, additional, Irimia, Manuel, additional, Fromm, Bastian, additional, Peterson, Kevin, additional, Das, Sabyasachi, additional, Hirano, Masayuki, additional, Rast, Jonathan, additional, Cooper, Max, additional, Paps, Jordi, additional, Pisani, Davide, additional, Kuratani, Shigeru, additional, Martin, Fergal, additional, Wang, Wen, additional, Donoghue, Philip, additional, and Zhang, Yong, additional

Published
2023
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8. Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences

Author

Yu, Daqi, primary, Ren, Yandong, additional, Uesaka, Masahiro, additional, Beavan, Alan J. S., additional, Muffato, Matthieu, additional, Shen, Jieyu, additional, Li, Yongxin, additional, Sato, Iori, additional, Wan, Wenting, additional, Clark, James W., additional, Keating, Joseph N., additional, Carlisle, Emily M., additional, Dearden, Richard P., additional, Giles, Sam, additional, Randle, Emma, additional, Sansom, Robert S., additional, Feuda, Roberto, additional, Fleming, James F., additional, Sugahara, Fumiaki, additional, Cummins, Carla, additional, Patricio, Mateus, additional, Akanni, Wasiu, additional, D'Aniello, Salvatore, additional, Bertolucci, Cristiano, additional, Irie, Naoki, additional, Alev, Cantas, additional, Sheng, Guojun, additional, de Mendoza, Alex, additional, Maeso, Ignacio, additional, Irimia, Manuel, additional, Fromm, Bastian, additional, Peterson, Kevin J., additional, Das, Sabyasachi, additional, Hirano, Masayuki, additional, Rast, Jonathan P., additional, Cooper, Max D., additional, Paps, Jordi, additional, Pisani, Davide, additional, Kuratani, Shigeru, additional, Martin, Fergal J., additional, Wang, Wen, additional, Donoghue, Philip C. J., additional, Zhang, Yong E., additional, and Pascual-Anaya, Juan, additional

Published
2023
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