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2. P38 Inhibition Prevents Herpes Simplex Virus Type 1 (HSV-1) Infection in Cultured Corneal Keratocytes

Author

Wang Hui-Fang, Song Xiu-Jun, Shen Jing-Ran, Hou Yu-Rong, Chen Bo-Yu, and Han Xian-Kui

Subjects
Time Factors, DNA Copy Number Variations, Cell Survival, Pyridines, p38 mitogen-activated protein kinases, Blotting, Western, Inflammation, Corneal Keratocytes, Enzyme-Linked Immunosorbent Assay, HSL and HSV, Herpesvirus 1, Human, Biology, medicine.disease_cause, Real-Time Polymerase Chain Reaction, p38 Mitogen-Activated Protein Kinases, Aldehyde Dehydrogenase 1 Family, Proinflammatory cytokine, Cellular and Molecular Neuroscience, Chlorocebus aethiops, medicine, Animals, Humans, Secretion, Vero Cells, Cells, Cultured, Dose-Response Relationship, Drug, Anti-Inflammatory Agents, Non-Steroidal, Imidazoles, Retinal Dehydrogenase, Herpes Simplex, Virology, Sensory Systems, Actins, Ophthalmology, Herpes simplex virus, Microscopy, Fluorescence, Cytokines, Interferon Regulatory Factor-3, medicine.symptom
Abstract

Purpose: To evaluate keratocyte viability and proinflammatory cytokine secretion induced by HSV-1 infection.Methods: Keratocytes were separated from corneal tissues obtained with the SMILE procedur...

Published
2020

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