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Ensuring a stable power supply in rural areas relies heavily on effective inspection of power equipment, particularly transmission lines (TLs). However, detecting TLs from aerial imagery can be challenging when dealing with misalignments between visible light (RGB) and infrared (IR) images, as well as mismatched high- and low-level features in convolutional networks. To address these limitations, we propose a novel Hierarchical Multi-Modal Enhancement Network (HMMEN) that integrates RGB and IR data for robust and accurate TL detection. Our method introduces two key components: (1) a Mutual Multi-Modal Enhanced Block (MMEB), which fuses and enhances hierarchical RGB and IR feature maps in a coarse-to-fine manner, and (2) a Feature Alignment Block (FAB) that corrects misalignments between decoder outputs and IR feature maps by leveraging deformable convolutions. We employ MobileNet-based encoders for both RGB and IR inputs to accommodate edge-computing constraints and reduce computational overhead. Experimental results on diverse weather and lighting conditionsfog, night, snow, and daytimedemonstrate the superiority and robustness of our approach compared to state-of-the-art methods, resulting in fewer false positives, enhanced boundary delineation, and better overall detection performance. This framework thus shows promise for practical large-scale power line inspections with unmanned aerial vehicles.

Multivariate Time Series Classification (MTSC) enables the analysis if complex temporal data, and thus serves as a cornerstone in various real-world applications, ranging from healthcare to finance. Since the relationship among variables in MTS usually contain crucial cues, a large number of graph-based MTSC approaches have been proposed, as the graph topology and edges can explicitly represent relationships among variables (channels), where not only various MTS graph representation learning strategies but also different Graph Neural Networks (GNNs) have been explored. Despite such progresses, there is no comprehensive study that fairly benchmarks and investigates the performances of existing widely-used graph representation learning strategies/GNN classifiers in the application of different MTSC tasks. In this paper, we present the first benchmark which systematically investigates the effectiveness of the widely-used three node feature definition strategies, four edge feature learning strategies and five GNN architecture, resulting in 60 different variants for graph-based MTSC. These variants are developed and evaluated with a standardized data pipeline and training/validation/testing strategy on 26 widely-used suspensor MTSC datasets. Our experiments highlight that node features significantly influence MTSC performance, while the visualization of edge features illustrates why adaptive edge learning outperforms other edge feature learning methods. The code of the proposed benchmark is publicly available at \url{https://github.com/CVI-yangwn/Benchmark-GNN-for-Multivariate-Time-Series-Classification}.

Artificial Intelligence is revolutionizing medical practice, enhancing diagnostic accuracy and healthcare delivery. However, its adaptation in medical settings still faces significant challenges, related to data availability and privacy constraints. Synthetic data has emerged as a promising solution to mitigate these issues, addressing data scarcity while preserving privacy. Recently, Latent Diffusion Models have emerged as a powerful tool for generating high-quality synthetic data. Meanwhile, the integration of different modalities has gained interest, emphasizing the need of models capable of handle multimodal medical data. Existing approaches struggle to integrate complementary information and lack the ability to generate modalities simultaneously. To address this challenge, we present MedCoDi-M, a 6.77-billion-parameter model, designed for multimodal medical data generation, that, following Foundation Model paradigm, exploits contrastive learning and large quantity of data to build a shared latent space which capture the relationships between different data modalities. Further, we introduce the Multi-Prompt training technique, which significantly boosts MedCoDi-M's generation under different settings. We extensively validate MedCoDi-M: first we benchmark it against five competitors on the MIMIC-CXR dataset, a state-of-the-art dataset for Chest X-ray and radiological report generation. Secondly, we perform a Visual Turing Test with expert radiologists to assess the realism and clinical relevance of the generated data, ensuring alignment with real-world scenarios. Finally, we assess the utility of MedCoDi-M in addressing key challenges in the medical field, such as anonymization, data scarcity and imbalance learning. The results are promising, demonstrating the applicability of MedCoDi-M in medical contexts. Project page is at https://cosbidev.github.io/MedCoDi-M/.

Face forgery detection (FFD) is devoted to detecting the authenticity of face images. Although current CNN-based works achieve outstanding performance in FFD, they are susceptible to capturing local forgery patterns generated by various manipulation methods. Though transformer-based detectors exhibit improvements in modeling global dependencies, they are not good at exploring local forgery artifacts. Hybrid transformer-based networks are designed to capture local and global manipulated traces, but they tend to suffer from the attention collapse issue as the transformer block goes deeper. Besides, soft labels are rarely available. In this paper, we propose a distilled transformer network (DTN) to capture both rich local and global forgery traces and learn general and common representations for different forgery faces. Specifically, we design a mixture of expert (MoE) module to mine various robust forgery embeddings. Moreover, a locally-enhanced vision transformer (LEVT) module is proposed to learn locally-enhanced global representations. We design a lightweight multi-attention scaling (MAS) module to avoid attention collapse, which can be plugged and played in any transformer-based models with only a slight increase in computational costs. In addition, we propose a deepfake self-distillation (DSD) scheme to provide the model with abundant soft label information. Extensive experiments show that the proposed method surpasses the state of the arts on five deepfake datasets., Comment: Accepted by Pattern Recognition

Accurately synthesizing talking face videos and capturing fine facial features for individuals with long hair presents a significant challenge. To tackle these challenges in existing methods, we propose a decomposed per-embedding Gaussian fields (DEGSTalk), a 3D Gaussian Splatting (3DGS)-based talking face synthesis method for generating realistic talking faces with long hairs. Our DEGSTalk employs Deformable Pre-Embedding Gaussian Fields, which dynamically adjust pre-embedding Gaussian primitives using implicit expression coefficients. This enables precise capture of dynamic facial regions and subtle expressions. Additionally, we propose a Dynamic Hair-Preserving Portrait Rendering technique to enhance the realism of long hair motions in the synthesized videos. Results show that DEGSTalk achieves improved realism and synthesis quality compared to existing approaches, particularly in handling complex facial dynamics and hair preservation. Our code will be publicly available at https://github.com/CVI-SZU/DEGSTalk., Comment: Accepted by ICASSP 2025

In the domain of facial recognition security, multimodal Face Anti-Spoofing (FAS) is essential for countering presentation attacks. However, existing technologies encounter challenges due to modality biases and imbalances, as well as domain shifts. Our research introduces a Mixture of Experts (MoE) model to address these issues effectively. We identified three limitations in traditional MoE approaches to multimodal FAS: (1) Coarse-grained experts' inability to capture nuanced spoofing indicators; (2) Gated networks' susceptibility to input noise affecting decision-making; (3) MoE's sensitivity to prompt tokens leading to overfitting with conventional learning methods. To mitigate these, we propose the Bypass Isolated Gating MoE (BIG-MoE) framework, featuring: (1) Fine-grained experts for enhanced detection of subtle spoofing cues; (2) An isolation gating mechanism to counteract input noise; (3) A novel differential convolutional prompt bypass enriching the gating network with critical local features, thereby improving perceptual capabilities. Extensive experiments on four benchmark datasets demonstrate significant generalization performance improvement in multimodal FAS task. The code is released at https://github.com/murInJ/BIG-MoE., Comment: Accepted by ICASSP 2025

Medical report generation is crucial for clinical diagnosis and patient management, summarizing diagnoses and recommendations based on medical imaging. However, existing work often overlook the clinical pipeline involved in report writing, where physicians typically conduct an initial quick review followed by a detailed examination. Moreover, current alignment methods may lead to misaligned relationships. To address these issues, we propose DAMPER, a dual-stage framework for medical report generation that mimics the clinical pipeline of report writing in two stages. In the first stage, a MeSH-Guided Coarse-Grained Alignment (MCG) stage that aligns chest X-ray (CXR) image features with medical subject headings (MeSH) features to generate a rough keyphrase representation of the overall impression. In the second stage, a Hypergraph-Enhanced Fine-Grained Alignment (HFG) stage that constructs hypergraphs for image patches and report annotations, modeling high-order relationships within each modality and performing hypergraph matching to capture semantic correlations between image regions and textual phrases. Finally,the coarse-grained visual features, generated MeSH representations, and visual hypergraph features are fed into a report decoder to produce the final medical report. Extensive experiments on public datasets demonstrate the effectiveness of DAMPER in generating comprehensive and accurate medical reports, outperforming state-of-the-art methods across various evaluation metrics.

Small lesions play a critical role in early disease diagnosis and intervention of severe infections. Popular models often face challenges in segmenting small lesions, as it occupies only a minor portion of an image, while down\_sampling operations may inevitably lose focus on local features of small lesions. To tackle the challenges, we propose a {\bf S}mall-{\bf S}ize-{\bf S}ensitive {\bf Mamba} ({\bf S$^3$-Mamba}), which promotes the sensitivity to small lesions across three dimensions: channel, spatial, and training strategy. Specifically, an Enhanced Visual State Space block is designed to focus on small lesions through multiple residual connections to preserve local features, and selectively amplify important details while suppressing irrelevant ones through channel-wise attention. A Tensor-based Cross-feature Multi-scale Attention is designed to integrate input image features and intermediate-layer features with edge features and exploit the attentive support of features across multiple scales, thereby retaining spatial details of small lesions at various granularities. Finally, we introduce a novel regularized curriculum learning to automatically assess lesion size and sample difficulty, and gradually focus from easy samples to hard ones like small lesions. Extensive experiments on three medical image segmentation datasets show the superiority of our S$^3$-Mamba, especially in segmenting small lesions. Our code is available at https://github.com/ErinWang2023/S3-Mamba., Comment: Accept by AAAI 2025

For efficient and high-fidelity local facial attribute editing, most existing editing methods either require additional fine-tuning for different editing effects or tend to affect beyond the editing regions. Alternatively, inpainting methods can edit the target image region while preserving external areas. However, current inpainting methods still suffer from the generation misalignment with facial attributes description and the loss of facial skin details. To address these challenges, (i) a novel data utilization strategy is introduced to construct datasets consisting of attribute-text-image triples from a data-driven perspective, (ii) a Causality-Aware Condition Adapter is proposed to enhance the contextual causality modeling of specific details, which encodes the skin details from the original image while preventing conflicts between these cues and textual conditions. In addition, a Skin Transition Frequency Guidance technique is introduced for the local modeling of contextual causality via sampling guidance driven by low-frequency alignment. Extensive quantitative and qualitative experiments demonstrate the effectiveness of our method in boosting both fidelity and editability for localized attribute editing. The code is available at https://github.com/connorxian/CA-Edit., Comment: accepted by aaai

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on general medical knowledge using licensing exams and knowledge question-answering tasks, their performance in the CDM in real-world scenarios is limited due to the lack of comprehensive testing datasets that mirror actual medical practice. To address this gap, we present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow. MedChain distinguishes itself from existing benchmarks with three key features of real-world clinical practice: personalization, interactivity, and sequentiality. Further, to tackle real-world CDM challenges, we also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses. MedChain-Agent demonstrates remarkable adaptability in gathering information dynamically and handling sequential clinical tasks, significantly outperforming existing approaches. The relevant dataset and code will be released upon acceptance of this paper.

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to bypass crucial morphological features that pathologists rely on for diagnosis. To address these challenges, we first introduce WSI-Bench, a large-scale morphology-aware benchmark containing 180k VQA pairs from 9,850 WSIs across 30 cancer types, designed to evaluate MLLMs' understanding of morphological characteristics crucial for accurate diagnosis. Building upon this benchmark, we present WSI-LLaVA, a novel framework for gigapixel WSI understanding that employs a three-stage training approach: WSI-text alignment, feature space alignment, and task-specific instruction tuning. To better assess model performance in pathological contexts, we develop two specialized WSI metrics: WSI-Precision and WSI-Relevance. Experimental results demonstrate that WSI-LLaVA outperforms existing models across all capability dimensions, with a significant improvement in morphological analysis, establishing a clear correlation between morphological understanding and diagnostic accuracy., Comment: 38 pages, 22 figures, 35 tables

Hair editing is a critical image synthesis task that aims to edit hair color and hairstyle using text descriptions or reference images, while preserving irrelevant attributes (e.g., identity, background, cloth). Many existing methods are based on StyleGAN to address this task. However, due to the limited spatial distribution of StyleGAN, it struggles with multiple hair color editing and facial preservation. Considering the advancements in diffusion models, we utilize Latent Diffusion Models (LDMs) for hairstyle editing. Our approach introduces Multi-stage Hairstyle Blend (MHB), effectively separating control of hair color and hairstyle in diffusion latent space. Additionally, we train a warping module to align the hair color with the target region. To further enhance multi-color hairstyle editing, we fine-tuned a CLIP model using a multi-color hairstyle dataset. Our method not only tackles the complexity of multi-color hairstyles but also addresses the challenge of preserving original colors during diffusion editing. Extensive experiments showcase the superiority of our method in editing multi-color hairstyles while preserving facial attributes given textual descriptions and reference images.

Domain generalization methods aim to learn transferable knowledge from source domains that can generalize well to unseen target domains. Recent studies show that neural networks frequently suffer from a simplicity-biased learning behavior which leads to over-reliance on specific frequency sets, namely as frequency shortcuts, instead of semantic information, resulting in poor generalization performance. Despite previous data augmentation techniques successfully enhancing generalization performances, they intend to apply more frequency shortcuts, thereby causing hallucinations of generalization improvement. In this paper, we aim to prevent such learning behavior of applying frequency shortcuts from a data-driven perspective. Given the theoretical justification of models' biased learning behavior on different spatial frequency components, which is based on the dataset frequency properties, we argue that the learning behavior on various frequency components could be manipulated by changing the dataset statistical structure in the Fourier domain. Intuitively, as frequency shortcuts are hidden in the dominant and highly dependent frequencies of dataset structure, dynamically perturbating the over-reliance frequency components could prevent the application of frequency shortcuts. To this end, we propose two effective data augmentation modules designed to collaboratively and adaptively adjust the frequency characteristic of the dataset, aiming to dynamically influence the learning behavior of the model and ultimately serving as a strategy to mitigate shortcut learning. Code is available at AdvFrequency (https://github.com/C0notSilly/AdvFrequency)., Comment: Accepted by NeurIPS 2024

Facial expression datasets remain limited in scale due to privacy concerns, the subjectivity of annotations, and the labor-intensive nature of data collection. This limitation poses a significant challenge for developing modern deep learning-based facial expression analysis models, particularly foundation models, that rely on large-scale data for optimal performance. To tackle the overarching and complex challenge, we introduce SynFER (Synthesis of Facial Expressions with Refined Control), a novel framework for synthesizing facial expression image data based on high-level textual descriptions as well as more fine-grained and precise control through facial action units. To ensure the quality and reliability of the synthetic data, we propose a semantic guidance technique to steer the generation process and a pseudo-label generator to help rectify the facial expression labels for the synthetic images. To demonstrate the generation fidelity and the effectiveness of the synthetic data from SynFER, we conduct extensive experiments on representation learning using both synthetic data and real-world data. Experiment results validate the efficacy of the proposed approach and the synthetic data. Notably, our approach achieves a 67.23% classification accuracy on AffectNet when training solely with synthetic data equivalent to the AffectNet training set size, which increases to 69.84% when scaling up to five times the original size. Our code will be made publicly available., Comment: Updated Results

Low-light images are commonly encountered in real-world scenarios, and numerous low-light image enhancement (LLIE) methods have been proposed to improve the visibility of these images. The primary goal of LLIE is to generate clearer images that are more visually pleasing to humans. However, the impact of LLIE methods in high-level vision tasks, such as image classification and object detection, which rely on high-quality image datasets, is not well {explored}. To explore the impact, we comprehensively evaluate LLIE methods on these high-level vision tasks by utilizing an empirical investigation comprising image classification and object detection experiments. The evaluation reveals a dichotomy: {\textit{While Low-Light Image Enhancement (LLIE) methods enhance human visual interpretation, their effect on computer vision tasks is inconsistent and can sometimes be harmful. }} Our findings suggest a disconnect between image enhancement for human visual perception and for machine analysis, indicating a need for LLIE methods tailored to support high-level vision tasks effectively. This insight is crucial for the development of LLIE techniques that align with the needs of both human and machine vision., Comment: 8 pages,8 figures

Remote Photoplethysmography (rPPG) is a non-contact method that uses facial video to predict changes in blood volume, enabling physiological metrics measurement. Traditional rPPG models often struggle with poor generalization capacity in unseen domains. Current solutions to this problem is to improve its generalization in the target domain through Domain Generalization (DG) or Domain Adaptation (DA). However, both traditional methods require access to both source domain data and target domain data, which cannot be implemented in scenarios with limited access to source data, and another issue is the privacy of accessing source domain data. In this paper, we propose the first Source-free Domain Adaptation benchmark for rPPG measurement (SFDA-rPPG), which overcomes these limitations by enabling effective domain adaptation without access to source domain data. Our framework incorporates a Three-Branch Spatio-Temporal Consistency Network (TSTC-Net) to enhance feature consistency across domains. Furthermore, we propose a new rPPG distribution alignment loss based on the Frequency-domain Wasserstein Distance (FWD), which leverages optimal transport to align power spectrum distributions across domains effectively and further enforces the alignment of the three branches. Extensive cross-domain experiments and ablation studies demonstrate the effectiveness of our proposed method in source-free domain adaptation settings. Our findings highlight the significant contribution of the proposed FWD loss for distributional alignment, providing a valuable reference for future research and applications. The source code is available at https://github.com/XieYiping66/SFDA-rPPG

The rapid development of photo-realistic face generation methods has raised significant concerns in society and academia, highlighting the urgent need for robust and generalizable face forgery detection (FFD) techniques. Although existing approaches mainly capture face forgery patterns using image modality, other modalities like fine-grained noises and texts are not fully explored, which limits the generalization capability of the model. In addition, most FFD methods tend to identify facial images generated by GAN, but struggle to detect unseen diffusion-synthesized ones. To address the limitations, we aim to leverage the cutting-edge foundation model, contrastive language-image pre-training (CLIP), to achieve generalizable diffusion face forgery detection (DFFD). In this paper, we propose a novel multi-modal fine-grained CLIP (MFCLIP) model, which mines comprehensive and fine-grained forgery traces across image-noise modalities via language-guided face forgery representation learning, to facilitate the advancement of DFFD. Specifically, we devise a fine-grained language encoder (FLE) that extracts fine global language features from hierarchical text prompts. We design a multi-modal vision encoder (MVE) to capture global image forgery embeddings as well as fine-grained noise forgery patterns extracted from the richest patch, and integrate them to mine general visual forgery traces. Moreover, we build an innovative plug-and-play sample pair attention (SPA) method to emphasize relevant negative pairs and suppress irrelevant ones, allowing cross-modality sample pairs to conduct more flexible alignment. Extensive experiments and visualizations show that our model outperforms the state of the arts on different settings like cross-generator, cross-forgery, and cross-dataset evaluations.

While large visual models (LVM) demonstrated significant potential in image understanding, due to the application of large-scale pre-training, the Segment Anything Model (SAM) has also achieved great success in the field of image segmentation, supporting flexible interactive cues and strong learning capabilities. However, SAM's performance often falls short in cross-domain and few-shot applications. Previous work has performed poorly in transferring prior knowledge from base models to new applications. To tackle this issue, we propose a task-adaptive auto-visual prompt framework, a new paradigm for Cross-dominan Few-shot segmentation (CD-FSS). First, a Multi-level Feature Fusion (MFF) was used for integrated feature extraction as prior knowledge. Besides, we incorporate a Class Domain Task-Adaptive Auto-Prompt (CDTAP) module to enable class-domain agnostic feature extraction and generate high-quality, learnable visual prompts. This significant advancement uses a unique generative approach to prompts alongside a comprehensive model structure and specialized prototype computation. While ensuring that the prior knowledge of SAM is not discarded, the new branch disentangles category and domain information through prototypes, guiding it in adapting the CD-FSS. Comprehensive experiments across four cross-domain datasets demonstrate that our model outperforms the state-of-the-art CD-FSS approach, achieving an average accuracy improvement of 1.3\% in the 1-shot setting and 11.76\% in the 5-shot setting.

The multilayer perceptron (MLP), a fundamental paradigm in current artificial intelligence, is widely applied in fields such as computer vision and natural language processing. However, the recently proposed Kolmogorov-Arnold Network (KAN), based on nonlinear additive connections, has been proven to achieve performance comparable to MLPs with significantly fewer parameters. Despite this potential, the use of a single activation function space results in reduced performance of KAN and related works across different tasks. To address this issue, we propose an activation space Selectable KAN (S-KAN). S-KAN employs an adaptive strategy to choose the possible activation mode for data at each feedforward KAN node. Our approach outperforms baseline methods in seven representative function fitting tasks and significantly surpasses MLP methods with the same level of parameters. Furthermore, we extend the structure of S-KAN and propose an activation space selectable Convolutional KAN (S-ConvKAN), which achieves leading results on four general image classification datasets. Our method mitigates the performance variability of the original KAN across different tasks and demonstrates through extensive experiments that feedforward KANs with selectable activations can achieve or even exceed the performance of MLP-based methods. This work contributes to the understanding of the data-centric design of new AI paradigms and provides a foundational reference for innovations in KAN-based network architectures., Comment: 12 pages, 6 figures. The code for this work will be released soon

Gaze estimation is pivotal in human scene comprehension tasks, particularly in medical diagnostic analysis. Eye-tracking technology facilitates the recording of physicians' ocular movements during image interpretation, thereby elucidating their visual attention patterns and information-processing strategies. In this paper, we initially define the context-aware gaze estimation problem in medical radiology report settings. To understand the attention allocation and cognitive behavior of radiologists during the medical image interpretation process, we propose a context-aware Gaze EstiMation (GEM) network that utilizes eye gaze data collected from radiologists to simulate their visual search behavior patterns throughout the image interpretation process. It consists of a context-awareness module, visual behavior graph construction, and visual behavior matching. Within the context-awareness module, we achieve intricate multimodal registration by establishing connections between medical reports and images. Subsequently, for a more accurate simulation of genuine visual search behavior patterns, we introduce a visual behavior graph structure, capturing such behavior through high-order relationships (edges) between gaze points (nodes). To maintain the authenticity of visual behavior, we devise a visual behavior-matching approach, adjusting the high-order relationships between them by matching the graph constructed from real and estimated gaze points. Extensive experiments on four publicly available datasets demonstrate the superiority of GEM over existing methods and its strong generalizability, which also provides a new direction for the effective utilization of diverse modalities in medical image interpretation and enhances the interpretability of models in the field of medical imaging. https://github.com/Tiger-SN/GEM, Comment: 9 figures

High-resolution point clouds~(HRPCD) anomaly detection~(AD) plays a critical role in precision machining and high-end equipment manufacturing. Despite considerable 3D-AD methods that have been proposed recently, they still cannot meet the requirements of the HRPCD-AD task. There are several challenges: i) It is difficult to directly capture HRPCD information due to large amounts of points at the sample level; ii) The advanced transformer-based methods usually obtain anisotropic features, leading to degradation of the representation; iii) The proportion of abnormal areas is very small, which makes it difficult to characterize. To address these challenges, we propose a novel group-level feature-based network, called Group3AD, which has a significantly efficient representation ability. First, we design an Intercluster Uniformity Network~(IUN) to present the mapping of different groups in the feature space as several clusters, and obtain a more uniform distribution between clusters representing different parts of the point clouds in the feature space. Then, an Intracluster Alignment Network~(IAN) is designed to encourage groups within the cluster to be distributed tightly in the feature space. In addition, we propose an Adaptive Group-Center Selection~(AGCS) based on geometric information to improve the pixel density of potential anomalous regions during inference. The experimental results verify the effectiveness of our proposed Group3AD, which surpasses Reg3D-AD by the margin of 5\% in terms of object-level AUROC on Real3D-AD. We provide the code and supplementary information on our website: https://github.com/M-3LAB/Group3AD., Comment: ACMMM24, 12 pages, 5 figures

Deep image registration has demonstrated exceptional accuracy and fast inference. Recent advances have adopted either multiple cascades or pyramid architectures to estimate dense deformation fields in a coarse-to-fine manner. However, due to the cascaded nature and repeated composition/warping operations on feature maps, these methods negatively increase memory usage during training and testing. Moreover, such approaches lack explicit constraints on the learning process of small deformations at different scales, thus lacking explainability. In this study, we introduce a model-driven WiNet that incrementally estimates scale-wise wavelet coefficients for the displacement/velocity field across various scales, utilizing the wavelet coefficients derived from the original input image pair. By exploiting the properties of the wavelet transform, these estimated coefficients facilitate the seamless reconstruction of a full-resolution displacement/velocity field via our devised inverse discrete wavelet transform (IDWT) layer. This approach avoids the complexities of cascading networks or composition operations, making our WiNet an explainable and efficient competitor with other coarse-to-fine methods. Extensive experimental results from two 3D datasets show that our WiNet is accurate and GPU efficient. The code is available at https://github.com/x-xc/WiNet ., Comment: Accepted by MICCAI 2024

Existing face forgery detection usually follows the paradigm of training models in a single domain, which leads to limited generalization capacity when unseen scenarios and unknown attacks occur. In this paper, we elaborately investigate the generalization capacity of deepfake detection models when jointly trained on multiple face forgery detection datasets. We first find a rapid degradation of detection accuracy when models are directly trained on combined datasets due to the discrepancy across collection scenarios and generation methods. To address the above issue, a Generalized Multi-Scenario Deepfake Detection framework (GM-DF) is proposed to serve multiple real-world scenarios by a unified model. First, we propose a hybrid expert modeling approach for domain-specific real/forgery feature extraction. Besides, as for the commonality representation, we use CLIP to extract the common features for better aligning visual and textual features across domains. Meanwhile, we introduce a masked image reconstruction mechanism to force models to capture rich forged details. Finally, we supervise the models via a domain-aware meta-learning strategy to further enhance their generalization capacities. Specifically, we design a novel domain alignment loss to strongly align the distributions of the meta-test domains and meta-train domains. Thus, the updated models are able to represent both specific and common real/forgery features across multiple datasets. In consideration of the lack of study of multi-dataset training, we establish a new benchmark leveraging multi-source data to fairly evaluate the models' generalization capacity on unseen scenarios. Both qualitative and quantitative experiments on five datasets conducted on traditional protocols as well as the proposed benchmark demonstrate the effectiveness of our approach.

Panoramic X-ray is a simple and effective tool for diagnosing dental diseases in clinical practice. When deep learning models are developed to assist dentist in interpreting panoramic X-rays, most of their performance suffers from the limited annotated data, which requires dentist's expertise and a lot of time cost. Although self-supervised learning (SSL) has been proposed to address this challenge, the two-stage process of pretraining and fine-tuning requires even more training time and computational resources. In this paper, we present a self-supervised auxiliary detection (SSAD) framework, which is plug-and-play and compatible with any detectors. It consists of a reconstruction branch and a detection branch. Both branches are trained simultaneously, sharing the same encoder, without the need for finetuning. The reconstruction branch learns to restore the tooth texture of healthy or diseased teeth, while the detection branch utilizes these learned features for diagnosis. To enhance the encoder's ability to capture fine-grained features, we incorporate the image encoder of SAM to construct a texture consistency (TC) loss, which extracts image embedding from the input and output of reconstruction branch, and then enforces both embedding into the same feature space. Extensive experiments on the public DENTEX dataset through three detection tasks demonstrate that the proposed SSAD framework achieves state-of-the-art performance compared to mainstream object detection methods and SSL methods. The code is available at https://github.com/Dylonsword/SSAD

Few-shot semantic segmentation (FSS) endeavors to segment unseen classes with only a few labeled samples. Current FSS methods are commonly built on the assumption that their training and application scenarios share similar domains, and their performances degrade significantly while applied to a distinct domain. To this end, we propose to leverage the cutting-edge foundation model, the Segment Anything Model (SAM), for generalization enhancement. The SAM however performs unsatisfactorily on domains that are distinct from its training data, which primarily comprise natural scene images, and it does not support automatic segmentation of specific semantics due to its interactive prompting mechanism. In our work, we introduce APSeg, a novel auto-prompt network for cross-domain few-shot semantic segmentation (CD-FSS), which is designed to be auto-prompted for guiding cross-domain segmentation. Specifically, we propose a Dual Prototype Anchor Transformation (DPAT) module that fuses pseudo query prototypes extracted based on cycle-consistency with support prototypes, allowing features to be transformed into a more stable domain-agnostic space. Additionally, a Meta Prompt Generator (MPG) module is introduced to automatically generate prompt embeddings, eliminating the need for manual visual prompts. We build an efficient model which can be applied directly to target domains without fine-tuning. Extensive experiments on four cross-domain datasets show that our model outperforms the state-of-the-art CD-FSS method by 5.24% and 3.10% in average accuracy on 1-shot and 5-shot settings, respectively., Comment: 15 pages, 9 figures

Surgical guide plate is an important tool for the dental implant surgery. However, the design process heavily relies on the dentist to manually simulate the implant angle and depth. When deep neural networks have been applied to assist the dentist quickly locates the implant position, most of them are not able to determine the implant depth. Inspired by the video grounding task which localizes the starting and ending time of the target video segment, in this paper, we simplify the implant depth prediction as video grounding and develop a Texture Perceive Implant Depth Prediction Network (TPNet), which enables us to directly output the implant depth without complex measurements of oral bone. TPNet consists of an implant region detector (IRD) and an implant depth prediction network (IDPNet). IRD is an object detector designed to crop the candidate implant volume from the CBCT, which greatly saves the computation resource. IDPNet takes the cropped CBCT data to predict the implant depth. A Texture Perceive Loss (TPL) is devised to enable the encoder of IDPNet to perceive the texture variation among slices. Extensive experiments on a large dental implant dataset demonstrated that the proposed TPNet achieves superior performance than the existing methods.

In the fight against the COVID-19 pandemic, leveraging artificial intelligence to predict disease outcomes from chest radiographic images represents a significant scientific aim. The challenge, however, lies in the scarcity of large, labeled datasets with compatible tasks for training deep learning models without leading to overfitting. Addressing this issue, we introduce a novel multi-dataset multi-task training framework that predicts COVID-19 prognostic outcomes from chest X-rays (CXR) by integrating correlated datasets from disparate sources, distant from conventional multi-task learning approaches, which rely on datasets with multiple and correlated labeling schemes. Our framework hypothesizes that assessing severity scores enhances the model's ability to classify prognostic severity groups, thereby improving its robustness and predictive power. The proposed architecture comprises a deep convolutional network that receives inputs from two publicly available CXR datasets, AIforCOVID for severity prognostic prediction and BRIXIA for severity score assessment, and branches into task-specific fully connected output networks. Moreover, we propose a multi-task loss function, incorporating an indicator function, to exploit multi-dataset integration. The effectiveness and robustness of the proposed approach are demonstrated through significant performance improvements in prognosis classification tasks across 18 different convolutional neural network backbones in different evaluation strategies. This improvement is evident over single-task baselines and standard transfer learning strategies, supported by extensive statistical analysis, showing great application potential.

Prototype learning is widely used in face recognition, which takes the row vectors of coefficient matrix in the last linear layer of the feature extraction model as the prototypes for each class. When the prototypes are updated using the facial sample feature gradients in the model training, they are prone to being pulled away from the class center by the hard samples, resulting in decreased overall model performance. In this paper, we explicitly define prototypes as the expectations of sample features in each class and design the empirical prototypes using the existing samples in the dataset. We then devise a strategy to adaptively update these empirical prototypes during the model training based on the similarity between the sample features and the empirical prototypes. Furthermore, we propose an empirical prototype learning (EPL) method, which utilizes an adaptive margin parameter with respect to sample features. EPL assigns larger margins to the normal samples and smaller margins to the hard samples, allowing the learned empirical prototypes to better reflect the class center dominated by the normal samples and finally pull the hard samples towards the empirical prototypes through the learning. The extensive experiments on MFR, IJB-C, LFW, CFP-FP, AgeDB, and MegaFace demonstrate the effectiveness of EPL. Our code is available at $\href{https://github.com/WakingHours-GitHub/EPL}{https://github.com/WakingHours-GitHub/EPL}$., Comment: 16pages, 2 figures, 6 tables

Large Language Models (LLMs) have gained significant attention in the field of natural language processing (NLP) due to their wide range of applications. However, training LLMs for languages other than English poses significant challenges, due to the difficulty in acquiring large-scale corpus and the requisite computing resources. In this paper, we propose ChatFlow, a cross-language transfer-based LLM, to address these challenges and train large Chinese language models in a cost-effective manner. We employ a mix of Chinese, English, and parallel corpus to continuously train the LLaMA2 model, aiming to align cross-language representations and facilitate the knowledge transfer specifically to the Chinese language model. In addition, we use a dynamic data sampler to progressively transition the model from unsupervised pre-training to supervised fine-tuning. Experimental results demonstrate that our approach accelerates model convergence and achieves superior performance. We evaluate ChatFlow on popular Chinese and English benchmarks, the results indicate that it outperforms other Chinese models post-trained on LLaMA-2-7B., Comment: Accepted by ICASSP 2024

Human facial action units (AUs) are mutually related in a hierarchical manner, as not only they are associated with each other in both spatial and temporal domains but also AUs located in the same/close facial regions show stronger relationships than those of different facial regions. While none of existing approach thoroughly model such hierarchical inter-dependencies among AUs, this paper proposes to comprehensively model multi-scale AU-related dynamic and hierarchical spatio-temporal relationship among AUs for their occurrences recognition. Specifically, we first propose a novel multi-scale temporal differencing network with an adaptive weighting block to explicitly capture facial dynamics across frames at different spatial scales, which specifically considers the heterogeneity of range and magnitude in different AUs' activation. Then, a two-stage strategy is introduced to hierarchically model the relationship among AUs based on their spatial distribution (i.e., local and cross-region AU relationship modelling). Experimental results achieved on BP4D and DISFA show that our approach is the new state-of-the-art in the field of AU occurrence recognition. Our code is publicly available at https://github.com/CVI-SZU/MDHR., Comment: Accepted to CVPR2024

Low-light image enhancement (LLIE) aims to improve low-illumination images. However, existing methods face two challenges: (1) uncertainty in restoration from diverse brightness degradations; (2) loss of texture and color information caused by noise suppression and light enhancement. In this paper, we propose a novel enhancement approach, CodeEnhance, by leveraging quantized priors and image refinement to address these challenges. In particular, we reframe LLIE as learning an image-to-code mapping from low-light images to discrete codebook, which has been learned from high-quality images. To enhance this process, a Semantic Embedding Module (SEM) is introduced to integrate semantic information with low-level features, and a Codebook Shift (CS) mechanism, designed to adapt the pre-learned codebook to better suit the distinct characteristics of our low-light dataset. Additionally, we present an Interactive Feature Transformation (IFT) module to refine texture and color information during image reconstruction, allowing for interactive enhancement based on user preferences. Extensive experiments on both real-world and synthetic benchmarks demonstrate that the incorporation of prior knowledge and controllable information transfer significantly enhances LLIE performance in terms of quality and fidelity. The proposed CodeEnhance exhibits superior robustness to various degradations, including uneven illumination, noise, and color distortion., Comment: 10 pages, 13 figures

Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable image segmentation. This variability not only reflects the inherent complexity and subjective nature of medical image interpretation but also directly impacts the development and evaluation of automated segmentation algorithms. Accurately modeling and quantifying this variability is essential for enhancing the robustness and clinical applicability of these algorithms. We report the set-up and summarize the benchmark results of the Quantification of Uncertainties in Biomedical Image Quantification Challenge (QUBIQ), which was organized in conjunction with International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2020 and 2021. The challenge focuses on the uncertainty quantification of medical image segmentation which considers the omnipresence of inter-rater variability in imaging datasets. The large collection of images with multi-rater annotations features various modalities such as MRI and CT; various organs such as the brain, prostate, kidney, and pancreas; and different image dimensions 2D-vs-3D. A total of 24 teams submitted different solutions to the problem, combining various baseline models, Bayesian neural networks, and ensemble model techniques. The obtained results indicate the importance of the ensemble models, as well as the need for further research to develop efficient 3D methods for uncertainty quantification methods in 3D segmentation tasks., Comment: initial technical report

This paper introduces the concept of uniform classification, which employs a unified threshold to classify all samples rather than adaptive threshold classifying each individual sample. We also propose the uniform classification accuracy as a metric to measure the model's performance in uniform classification. Furthermore, begin with a naive loss, we mathematically derive a loss function suitable for the uniform classification, which is the BCE function integrated with a unified bias. We demonstrate the unified threshold could be learned via the bias. The extensive experiments on six classification datasets and three feature extraction models show that, compared to the SoftMax loss, the models trained with the BCE loss not only exhibit higher uniform classification accuracy but also higher sample-wise classification accuracy. In addition, the learned bias from BCE loss is very close to the unified threshold used in the uniform classification. The features extracted by the models trained with BCE loss not only possess uniformity but also demonstrate better intra-class compactness and inter-class distinctiveness, yielding superior performance on open-set tasks such as face recognition.

The vulnerability of automated fingerprint recognition systems (AFRSs) to presentation attacks (PAs) promotes the vigorous development of PA detection (PAD) technology. However, PAD methods have been limited by information loss and poor generalization ability, resulting in new PA materials and fingerprint sensors. This paper thus proposes a global-local model-based PAD (RTK-PAD) method to overcome those limitations to some extent. The proposed method consists of three modules, called: 1) the global module; 2) the local module; and 3) the rethinking module. By adopting the cut-out-based global module, a global spoofness score predicted from nonlocal features of the entire fingerprint images can be achieved. While by using the texture in-painting-based local module, a local spoofness score predicted from fingerprint patches is obtained. The two modules are not independent but connected through our proposed rethinking module by localizing two discriminative patches for the local module based on the global spoofness score. Finally, the fusion spoofness score by averaging the global and local spoofness scores is used for PAD. Our experimental results evaluated on LivDet 2017 show that the proposed RTK-PAD can achieve an average classification error (ACE) of 2.28% and a true detection rate (TDR) of 91.19% when the false detection rate (FDR) equals 1.0%, which significantly outperformed the state-of-the-art methods by $\sim$10% in terms of TDR (91.19% versus 80.74%)., Comment: This paper was accepted by IEEE Transactions on Cybernetics. Current version is updated with minor revisions on introduction and related works

The significant breakthroughs of Medical Multi-Modal Large Language Models (Med-MLLMs) renovate modern healthcare with robust information synthesis and medical decision support. However, these models are often evaluated on benchmarks that are unsuitable for the Med-MLLMs due to the complexity of real-world diagnostics across diverse specialties. To address this gap, we introduce Asclepius, a novel Med-MLLM benchmark that comprehensively assesses Med-MLLMs in terms of: distinct medical specialties (cardiovascular, gastroenterology, etc.) and different diagnostic capacities (perception, disease analysis, etc.). Grounded in 3 proposed core principles, Asclepius ensures a comprehensive evaluation by encompassing 15 medical specialties, stratifying into 3 main categories and 8 sub-categories of clinical tasks, and exempting overlap with existing VQA dataset. We further provide an in-depth analysis of 6 Med-MLLMs and compare them with 3 human specialists, providing insights into their competencies and limitations in various medical contexts. Our work not only advances the understanding of Med-MLLMs' capabilities but also sets a precedent for future evaluations and the safe deployment of these models in clinical environments., Comment: 20 pages, 15 figures

Adversarial examples generated by a surrogate model typically exhibit limited transferability to unknown target systems. To address this problem, many transferability enhancement approaches (e.g., input transformation and model augmentation) have been proposed. However, they show poor performances in attacking systems having different model genera from the surrogate model. In this paper, we propose a novel and generic attacking strategy, called Deformation-Constrained Warping Attack (DeCoWA), that can be effectively applied to cross model genus attack. Specifically, DeCoWA firstly augments input examples via an elastic deformation, namely Deformation-Constrained Warping (DeCoW), to obtain rich local details of the augmented input. To avoid severe distortion of global semantics led by random deformation, DeCoW further constrains the strength and direction of the warping transformation by a novel adaptive control strategy. Extensive experiments demonstrate that the transferable examples crafted by our DeCoWA on CNN surrogates can significantly hinder the performance of Transformers (and vice versa) on various tasks, including image classification, video action recognition, and audio recognition. Code is made available at https://github.com/LinQinLiang/DeCoWA., Comment: AAAI 2024

The rapid advancement of photorealistic generators has reached a critical juncture where the discrepancy between authentic and manipulated images is increasingly indistinguishable. Thus, benchmarking and advancing techniques detecting digital manipulation become an urgent issue. Although there have been a number of publicly available face forgery datasets, the forgery faces are mostly generated using GAN-based synthesis technology, which does not involve the most recent technologies like diffusion. The diversity and quality of images generated by diffusion models have been significantly improved and thus a much more challenging face forgery dataset shall be used to evaluate SOTA forgery detection literature. In this paper, we propose a large-scale, diverse, and fine-grained high-fidelity dataset, namely GenFace, to facilitate the advancement of deepfake detection, which contains a large number of forgery faces generated by advanced generators such as the diffusion-based model and more detailed labels about the manipulation approaches and adopted generators. In addition to evaluating SOTA approaches on our benchmark, we design an innovative cross appearance-edge learning (CAEL) detector to capture multi-grained appearance and edge global representations, and detect discriminative and general forgery traces. Moreover, we devise an appearance-edge cross-attention (AECA) module to explore the various integrations across two domains. Extensive experiment results and visualizations show that our detection model outperforms the state of the arts on different settings like cross-generator, cross-forgery, and cross-dataset evaluations. Code and datasets will be available at \url{https://github.com/Jenine-321/GenFace, Comment: Accepted by IEEE Transactions on Information Forensics and Security

Due to the poor prognosis of Pancreatic cancer, accurate early detection and segmentation are critical for improving treatment outcomes. However, pancreatic segmentation is challenged by blurred boundaries, high shape variability, and class imbalance. To tackle these problems, we propose a multiscale attention network with shape context and prior constraint for robust pancreas segmentation. Specifically, we proposed a Multi-scale Feature Extraction Module (MFE) and a Mixed-scale Attention Integration Module (MAI) to address unclear pancreas boundaries. Furthermore, a Shape Context Memory (SCM) module is introduced to jointly model semantics across scales and pancreatic shape. Active Shape Model (ASM) is further used to model the shape priors. Experiments on NIH and MSD datasets demonstrate the efficacy of our model, which improves the state-of-the-art Dice Score for 1.01% and 1.03% respectively. Our architecture provides robust segmentation performance, against the blurry boundaries, and variations in scale and shape of pancreas., Comment: 9 pages,6 figures

To address these issues, we propose a novel Adaptive patch-word Matching (AdaMatch) model to correlate chest X-ray (CXR) image regions with words in medical reports and apply it to CXR-report generation to provide explainability for the generation process. AdaMatch exploits the fine-grained relation between adaptive patches and words to provide explanations of specific image regions with corresponding words. To capture the abnormal regions of varying sizes and positions, we introduce the Adaptive Patch extraction (AdaPatch) module to acquire the adaptive patches for these regions adaptively. In order to provide explicit explainability for CXR-report generation task, we propose an AdaMatch-based bidirectional large language model for Cyclic CXR-report generation (AdaMatch-Cyclic). It employs the AdaMatch to obtain the keywords for CXR images and `keypatches' for medical reports as hints to guide CXR-report generation. Extensive experiments on two publicly available CXR datasets prove the effectiveness of our method and its superior performance to existing methods., Comment: Accepted by ACL 2024

In recent years, self-supervised contrastive learning has emerged as a distinguished paradigm in the artificial intelligence landscape. It facilitates unsupervised feature learning through contrastive delineations at the instance level. However, crafting an effective self-supervised paradigm remains a pivotal challenge within this field. This paper delves into two crucial factors impacting self-supervised contrastive learning-bach size and pretext tasks, and from a data processing standpoint, proposes an adaptive technique of batch fusion. The proposed method, via dimensionality reduction and reconstruction of batch data, enables formerly isolated individual data to partake in intra-batch communication through the Embedding Layer. Moreover, it adaptively amplifies the self-supervised feature encoding capability as the training progresses. We conducted a linear classification test of this method based on the classic contrastive learning framework on ImageNet-1k. The empirical findings illustrate that our approach achieves state-of-the-art performance under equitable comparisons. Benefiting from its "plug-and-play" characteristics, we further explored other contrastive learning methods. On the ImageNet-100, compared to the original performance, the top1 has seen a maximum increase of 1.25%. We suggest that the proposed method may contribute to the advancement of data-driven self-supervised learning research, bringing a fresh perspective to this community., Comment: 14 pages, 2 figures, the code of this paper will be released soon

Sample-to-class-based face recognition models can not fully explore the cross-sample relationship among large amounts of facial images, while sample-to-sample-based models require sophisticated pairing processes for training. Furthermore, neither method satisfies the requirements of real-world face verification applications, which expect a unified threshold separating positive from negative facial pairs. In this paper, we propose a unified threshold integrated sample-to-sample based loss (USS loss), which features an explicit unified threshold for distinguishing positive from negative pairs. Inspired by our USS loss, we also derive the sample-to-sample based softmax and BCE losses, and discuss their relationship. Extensive evaluation on multiple benchmark datasets, including MFR, IJB-C, LFW, CFP-FP, AgeDB, and MegaFace, demonstrates that the proposed USS loss is highly efficient and can work seamlessly with sample-to-class-based losses. The embedded loss (USS and sample-to-class Softmax loss) overcomes the pitfalls of previous approaches and the trained facial model UniTSFace exhibits exceptional performance, outperforming state-of-the-art methods, such as CosFace, ArcFace, VPL, AnchorFace, and UNPG. Our code is available., Comment: Accepted by Neurips 2023

In implant prosthesis treatment, the surgical guide of implant is used to ensure accurate implantation. However, such design heavily relies on the manual location of the implant position. When deep neural network has been proposed to assist the dentist in locating the implant position, most of them take a single slice as input, which do not fully explore 3D contextual information and ignoring the influence of implant slope. In this paper, we design a Text Guided 3D Context and Slope Aware Triple Network (TCSloT) which enables the perception of contextual information from multiple adjacent slices and awareness of variation of implant slopes. A Texture Variation Perception (TVP) module is correspondingly elaborated to process the multiple slices and capture the texture variation among slices and a Slope-Aware Loss (SAL) is proposed to dynamically assign varying weights for the regression head. Additionally, we design a conditional text guidance (CTG) module to integrate the text condition (i.e., left, middle and right) from the CLIP for assisting the implant position prediction. Extensive experiments on a dental implant dataset through five-fold cross-validation demonstrated that the proposed TCSloT achieves superior performance than existing methods.

In this study, the structural problems of the YOLOv5 model were analyzed emphatically. Based on the characteristics of fine defects in artificial leather, four innovative structures, namely DFP, IFF, AMP, and EOS, were designed. These advancements led to the proposal of a high-performance artificial leather fine defect detection model named YOLOD. YOLOD demonstrated outstanding performance on the artificial leather defect dataset, achieving an impressive increase of 11.7% - 13.5% in AP_50 compared to YOLOv5, along with a significant reduction of 5.2% - 7.2% in the error detection rate. Moreover, YOLOD also exhibited remarkable performance on the general MS-COCO dataset, with an increase of 0.4% - 2.6% in AP compared to YOLOv5, and a rise of 2.5% - 4.1% in AP_S compared to YOLOv5. These results demonstrate the superiority of YOLOD in both artificial leather defect detection and general object detection tasks, making it a highly efficient and effective model for real-world applications.

Verbal and non-verbal human reaction generation is a challenging task, as different reactions could be appropriate for responding to the same behaviour. This paper proposes the first multiple and multimodal (verbal and nonverbal) appropriate human reaction generation framework that can generate appropriate and realistic human-style reactions (displayed in the form of synchronised text, audio and video streams) in response to an input user behaviour. This novel technique can be applied to various human-computer interaction scenarios by generating appropriate virtual agent/robot behaviours. Our demo is available at \url{https://github.com/SSYSteve/MRecGen}.

When deep neural network has been proposed to assist the dentist in designing the location of dental implant, most of them are targeting simple cases where only one missing tooth is available. As a result, literature works do not work well when there are multiple missing teeth and easily generate false predictions when the teeth are sparsely distributed. In this paper, we are trying to integrate a weak supervision text, the target region, to the implant position regression network, to address above issues. We propose a text condition embedded implant position regression network (TCEIP), to embed the text condition into the encoder-decoder framework for improvement of the regression performance. A cross-modal interaction that consists of cross-modal attention (CMA) and knowledge alignment module (KAM) is proposed to facilitate the interaction between features of images and texts. The CMA module performs a cross-attention between the image feature and the text condition, and the KAM mitigates the knowledge gap between the image feature and the image encoder of the CLIP. Extensive experiments on a dental implant dataset through five-fold cross-validation demonstrated that the proposed TCEIP achieves superior performance than existing methods., Comment: MICCAI 2023

In dyadic interaction, predicting the listener's facial reactions is challenging as different reactions could be appropriate in response to the same speaker's behaviour. Previous approaches predominantly treated this task as an interpolation or fitting problem, emphasizing deterministic outcomes but ignoring the diversity and uncertainty of human facial reactions. Furthermore, these methods often failed to model short-range and long-range dependencies within the interaction context, leading to issues in the synchrony and appropriateness of the generated facial reactions. To address these limitations, this paper reformulates the task as an extrapolation or prediction problem, and proposes an novel framework (called ReactFace) to generate multiple different but appropriate facial reactions from a speaker behaviour rather than merely replicating the corresponding listener facial behaviours. Our ReactFace generates multiple different but appropriate photo-realistic human facial reactions by: (i) learning an appropriate facial reaction distribution representing multiple different but appropriate facial reactions; and (ii) synchronizing the generated facial reactions with the speaker verbal and non-verbal behaviours at each time stamp, resulting in realistic 2D facial reaction sequences. Experimental results demonstrate the effectiveness of our approach in generating multiple diverse, synchronized, and appropriate facial reactions from each speaker's behaviour. The quality of the generated facial reactions is intimately tied to the speaker's speech and facial expressions, achieved through our novel speaker-listener interaction modules. Our code is made publicly available at \url{https://github.com/lingjivoo/ReactFace}., Comment: Accepted to IEEE Transactions on Visualization and Computer Graphics (TVCG), 18 pages, 10 figures