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Sea-land breeze (SLB) is widely known as a common wind circulation in coastal cities, which plays an important role to heat transport and pollution diffusion. Using 21-year observation data, a continuous decrease of SLB is discovered in a Chinese metropolis city - Shanghai. In general, the thermodynamic difference between sea and land accounts for the magnitude of SLB. However, other factors associated with urbanization could also affect the SLB significantly, such as anthropogenic aerosol loading, surface roughness, heat release, and so on. This study statistically analyzes the influence of these factors on SLB under the background of global warming. As expected, the decrease of SLB is a combined effect of global warming and great urbanization in Shanghai. The latter, which affects the circulation in both thermodynamic and dynamic ways, is consisted of three parts: temperature increase with urbanization, change of atmospheric radiative forcing, and variation of the underlying surface. At night, the urbanization effect and global warming effect play the similar role by decreasing the temperature gap between sea and land, which would cause the decrease of land wind. At day, decreasing downwelling solar radiation partially offsets the temperature increase caused by both global warming and urbanization although the increasing trend of temperature remains. Different from the expected increasing trend of sea breeze based on the increasing temperature in Shanghai, sea breeze demonstrates a decreasing trend, which could be caused by the dynamic effect from increased surface roughness in Shanghai along with the cooling contribution from radiation-influential factors such as anthropogenic aerosols. • Both the SLB days and magnitude show decreasing trends over Shanghai from 1994 to 2014. • The effects of thermodynamic and dynamic influential factors to SLB circulation are analyzed. • Urbanization likely contributes more to the decreasing trends of land winds than marine winds. [ABSTRACT FROM AUTHOR]

An experimental model for heart-mural coronary artery-myocardial bridge was established based on the theory of haemodynamics. The application of the model demonstrated that it can repeat to great extent the phenomenon of the myocardial bridge compressing the mural coronary artery, which results in abnormal haemodynamic characteristics. The results of simulation experiments are mostly consistent with clinical research. [ABSTRACT FROM AUTHOR]

Abstract: In order to create a hemodynamic environment that can simulate the physiological condition of arteries, an in vitro experiment apparatus was designed whose key modules were compliance chamber and after-load. These two modules were developed based on the theories of hemodynamics. Both the normal and shear stress to which endothelial cells are exposed can be controlled with these modules, thus facilitating the research of endothelial cells subjected to stresses. [Copyright &y& Elsevier]

Zinc is an indispensable trace element and important for both bacteria and eukaryotes. Zn homeostasis is established by Zn2+ transport and regulation system. Hosts have developed mechanisms for Zn restricting or toxicosis in response to infections. In order to grow and multiply in the infected host, bacteria have progressed strict zinc transportation and regulation system, such as ZnuABC. Zinc is critically involved in a plethora of metabolic and virulence pathways and is paramount important in infection. Therefore, there could be possibilities to use zinc transporters as a very promising target for the development of novel antimicrobial strategies.

The present paper is to study the center line of the plantar pressure of normal young people, and to find the relation between center line of the plantar pressure and gait stability and balance. The paper gives the testing principle and calculating methods for geometric center of plantar pressure distribution and the center of pressure due to the techniques of footprint frame. The calculating formulas in both x direction and y direction are also deduced in the paper. In the experiments carried out in our laboratory, the gait parameters of 131 young subjects walking as usual speed were acquired, and 14 young subjects of the total were specially analyzed. We then provided reference data for the walking gait database of young people, including time parameters, space parameters and plantar pressure parameters. We also obtained the line of geometry center and pressure center under the foot. We found that the differences existed in normal people's geometric center line and the pressure center line. The center of pressure trajectory revealed foot movement stability. The length and lateral changes of the center line of the plantar pressure could be applied to analysis of the plantar pressure of all kinds of people. The results in this paper are useful in clinical foot disease diagnosis and evaluation of surgical effect.

A model of fluid dynamics related to the myocardial bridginged and mural coronary artery was designed and manufactured according to the physical principle and characteristic of the mural coronary artery. The model can imitate systematically well the effect of myocardial bridging on hemodynamic change of the mural coronary artery under different controlled experimental parameter. The methodology is proved to be feasible and has good prosperity of experimental study.