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Ex-vivo MRI offers invaluable insights into the complexity of the human brain, enabling high-resolution anatomical delineation and integration with histopathology, and thus, contributes to both basic and clinical studies on normal and pathological brains. However, ex-vivo MRI is challenging in sample preparation, acquisition, and data analysis, and existing ex-vivo MRI datasets are often single image modality and lack of ethnic diversity. In our study, we aimed to address these limitations by constructing a comprehensive multimodal MRI database acquired from six ex-vivo Chinese human brains. This database included structural MRI, high-angular resolution diffusion MRI, quantitative susceptibility mapping, and quantitative T1 and T2 maps, which enabled multifaceted depiction of brain microstructure and connectivity. Furthermore, we generated population-averaged multimodal templates and the segmentation labels to facilitate analysis of ex-vivo brain MRI. This public database offers a collection of high-resolution and multi-parametric ex-vivo human brain MRI and filled the gap of lacking Asian brain samples in existing databases.

Accurate tissue segmentation in fetal brain MRI remains challenging due to the dynamically changing anatomical anatomy and contrast during fetal development. To enhance segmentation accuracy throughout gestation, we introduced AtlasSeg, a dual-U-shape convolution network incorporating gestational age (GA) specific information as guidance. By providing a publicly available fetal brain atlas with segmentation label at the corresponding GA, AtlasSeg effectively extracted the contextual features of age-specific patterns in atlas branch and generated tissue segmentation in segmentation branch. Multi-scale attentive atlas feature fusions were constructed in all stages during encoding and decoding, giving rise to a dual-U-shape network to assist feature flow and information interactions between two branches. AtlasSeg outperformed six well-known segmentation networks in both our internal fetal brain MRI dataset and the external FeTA dataset. Ablation experiments demonstrate the efficiency of atlas guidance and the attention mechanism. The proposed AtlasSeg demonstrated superior segmentation performance against other convolution networks with higher segmentation accuracy, and may facilitate fetal brain MRI analysis in large-scale fetal brain studies.

The Segment Anything Model (SAM) has demonstrated strong performance in image segmentation of natural scene images. However, its effectiveness diminishes markedly when applied to specific scientific domains, such as Scanning Probe Microscope (SPM) images. This decline in accuracy can be attributed to the distinct data distribution and limited availability of the data inherent in the scientific images. On the other hand, the acquisition of adequate SPM datasets is both time-intensive and laborious as well as skill-dependent. To address these challenges, we propose an Adaptive Prompt Learning with SAM (APL-SAM) framework tailored for few-shot SPM image segmentation. Our approach incorporates two key innovations to enhance SAM: 1) An Adaptive Prompt Learning module leverages few-shot embeddings derived from limited support set to learn adaptively central representatives, serving as visual prompts. This innovation eliminates the need for time-consuming online user interactions for providing prompts, such as exhaustively marking points and bounding boxes slice by slice; 2) A multi-source, multi-level mask decoder specifically designed for few-shot SPM image segmentation is introduced, which can effectively capture the correspondence between the support and query images. To facilitate comprehensive training and evaluation, we introduce a new dataset, SPM-Seg, curated for SPM image segmentation. Extensive experiments on this dataset reveal that the proposed APL-SAM framework significantly outperforms the original SAM, achieving over a 30% improvement in terms of Dice Similarity Coefficient with only one-shot guidance. Moreover, APL-SAM surpasses state-of-the-art few-shot segmentation methods and even fully supervised approaches in performance. Code and dataset used in this study will be made available upon acceptance., Comment: 10 pages, 7 figures

Noisy labels are inevitable, even in well-annotated datasets. The detection of noisy labels is of significant importance to enhance the robustness of speaker recognition models. In this paper, we propose a novel noisy label detection approach based on two new statistical metrics: Continuous Inconsistent Counting (CIC) and Total Inconsistent Counting (TIC). These metrics are calculated through Cross-Epoch Counting (CEC) and correspond to the early and late stages of training, respectively. Additionally, we categorize samples based on their prediction results into three categories: inconsistent samples, hard samples, and easy samples. During training, we gradually increase the difficulty of hard samples to update model parameters, preventing noisy labels from being overfitted. Compared to contrastive schemes, our approach not only achieves the best performance in speaker verification but also excels in noisy label detection., Comment: interspeech 2024

Although entanglement is both a central ingredient in our understanding of quantum many-body systems and an essential resource for quantum technologies, we only have a limited ability to quantify entanglement in real quantum materials. Thus far, entanglement metrology in quantum materials has been limited to measurements involving Hermitian operators, such as the detection of spin entanglement using inelastic neutron scattering. Here, we devise a method to extract the quantum Fisher information (QFI) from non-Hermitian operators and formulate an entanglement witness for resonant inelastic x-ray scattering (RIXS). Our approach is then applied to the model iridate dimer system Ba$_3$CeIr$_2$O$_9$ and used to directly test for entanglement of the electronic orbitals between neighboring Ir sites. We find that entanglement is challenging to detect under standard conditions, but that it could be achieved by analyzing the outgoing x-ray polarization or via specific choices of momentum and energy. Our protocol provides a new handle for entanglement detection, which offers routes to related types of entanglement witness (such as orbitally-resolved measurements) and to the generalization to out-of-equilibrium settings accessed in ultrafast settings., Comment: 10 pages, 8 figures

The structure of quantum mechanics forbids a bipartite scenario for masking quantum information, however, it allows multipartite maskers. The Latin squares are found to be closely related to a series of tripartite maskers. This adds another item, significantly different from the original no-cloning theorem, to the no-go theorems. On the other hand, anyonic excitations in two dimensions exhibit exotic collective behaviors of quantum physics, and open the avenue of fault-tolerant topological quantum computing. Here, we give the Latin-square construction of Abelian and Ising anyons %of in the Kitaev model and study the maskable space configuration in anyonic space. The circling and braiding of Kitaev anyons are masking operations on extended hyperdisks in anyonic space. We also realize quantum information masking in a teleportation way in the Kitaev Ising anyon model., Comment: 7 pages, 4 figures

The pursuit of discovering new high-temperature superconductors that diverge from the copper-based paradigm1-3 carries profound implications for elucidating mechanisms behind superconductivity and may also enable new applications4-8. Here, our investigation reveals that application of pressure effectively suppresses the spin and charge order in trilayer nickelate La4Ni3O10-{\delta} single crystals, leading to the emergence of superconductivity with a maximum critical temperature (Tc) of around 30 K at 69.0 GPa. The DC susceptibility measurements confirm a substantial diamagnetic response below Tc, indicating the presence of bulk superconductivity with a volume fraction exceeding 80%. In the normal state, we observe a "strange metal" behavior, characterized by a linear temperature-dependent resistance extending up to 300 K. Furthermore, the layer-dependent superconductivity observed hints at a unique interlayer coupling mechanism specific to nickelates, setting them apart from cuprates in this regard. Our findings provide crucial insights into the fundamental mechanisms underpinning superconductivity, while also introducing a new material platform to explore the intricate interplay between the spin/charge order, flat band structures, interlayer coupling, strange metal behavior and high-temperature superconductivity., Comment: Supplementary information included

The initial seed based on the convolutional neural network (CNN) for weakly supervised semantic segmentation always highlights the most discriminative regions but fails to identify the global target information. Methods based on transformers have been proposed successively benefiting from the advantage of capturing long-range feature representations. However, we observe a flaw regardless of the gifts based on the transformer. Given a class, the initial seeds generated based on the transformer may invade regions belonging to other classes. Inspired by the mentioned issues, we devise a simple yet effective method with Multi-estimations Complementary Patch (MECP) strategy and Adaptive Conflict Module (ACM), dubbed MECPformer. Given an image, we manipulate it with the MECP strategy at different epochs, and the network mines and deeply fuses the semantic information at different levels. In addition, ACM adaptively removes conflicting pixels and exploits the network self-training capability to mine potential target information. Without bells and whistles, our MECPformer has reached new state-of-the-art 72.0% mIoU on the PASCAL VOC 2012 and 42.4% on MS COCO 2014 dataset. The code is available at https://github.com/ChunmengLiu1/MECPformer.

Composite materials with 3D architectures are desirable in a variety of applications for the capability of tailoring their properties to meet multiple functional requirements. By the arrangement of materials' internal components, structure design is of great significance in tuning the properties of the composites. However, most of the composite structures are proposed by empirical designs following existing patterns. Hindered by the complexity of 3D structures, it is hard to extract customized structures with multiple desired properties from large design space. Here we report a multi-objective driven Wasserstein generative adversarial network (MDWGAN) to implement inverse designs of 3D composite structures according to given geometrical, structural and mechanical requirements. Our framework consists a GAN based network which generates 3D composite structures possessing with similar geometrical and structural features to the target dataset. Besides, multiple objectives are introduced to our framework for the control of mechanical property and isotropy of the composites. Real time calculation of the properties in training iterations is achieved by an accurate surrogate model. We constructed a small and concise dataset to illustrate our framework. With multiple objectives combined by their weight, and the 3D-GAN act as a soft constraint, our framework is proved to be capable of tuning the properties of the generated composites in multiple aspects, while keeping the selected features of different kinds of structures. The feasibility on small dataset and potential scalability on objectives of other properties make our work a novel, effective approach to provide fast, experience free composite structure designs for various functional materials.

The energy spectrum of topological semimetals contains protected degeneracies in reciprocal space that correspond to Weyl, Dirac, or multifold fermionic states. To exploit the unconventional properties of these states, one has to access the electronic structure of the three-dimensional bulk. In this work, we present the first joint theory-experiment study of the electronic structure of a candidate topological semimetal with resonant inelastic X-ray scattering (RIXS). We resolve the bulk electronic states of FeSi using momentum-dependent RIXS at the Fe $L_3$ edge. We observe a broad excitation continuum devoid of sharp features, consistent with particle-hole scattering in an underlying electronic band structure. Using density functional theory (DFT), we calculate the electronic structure of FeSi and derive a band theory formulation of RIXS in the fast collision approximation to model the scattering process with zero adjustable parameters. While band theory predicts an excitation continuum with broad spectral features similar to the observed ones, discrepancies between theory and experiment suggest the presence of low-energy processes that DFT alone does not account for. This first study of RIXS in a topological semimetal shows that RIXS is a useful tool for revealing unanticipated behavior of bulk electronic states in this class of materials., Comment: v2: published version

The discovery of pressure-induced superconductivity in helimagnets (CrAs, MnP) has attracted considerable interest in understanding the relationship between complex magnetism and unconventional superconductivity. However, the nature of the magnetism and magnetic interactions that drive the unusual double-helical magnetic order in these materials remains unclear. Here, we report neutron scattering measurements of magnetic excitations in CrAs single crystals at ambient pressure. Our experiments reveal well defined spin wave excitations up to about 150 meV with a pseudogap below 7 meV, which can be effectively described by the Heisenberg model with nearest neighbor exchange interactions. Most surprisingly, the spin excitations are largely quenched above the Neel temperature, in contrast to cuprates and iron pnictides where the spectral weight is mostly preserved in the paramagnetic state. Our results suggest that the helimagnetic order is driven by strongly frustrated exchange interactions, and that CrAs is at the verge of itinerant and correlation-induced localized states, which is therefore highly pressure-tunable and favorable for superconductivity., Comment: 6 pages, 4 figures

There are still two problems in SDD causing some inaccurate results: (1) In the process of feature extraction, with the layer-by-layer acquisition of semantic information, local information is gradually lost, resulting into less representative feature maps; (2) During the Non-Maximum Suppression (NMS) algorithm due to inconsistency in classification and regression tasks, the classification confidence and predicted detection position cannot accurately indicate the position of the prediction boxes. Methods: In order to address these aforementioned issues, we propose a new architecture, a modified version of Single Shot Multibox Detector (SSD), named Precise Single Stage Detector (PSSD). Firstly, we improve the features by adding extra layers to SSD. Secondly, we construct a simple and effective feature enhancement module to expand the receptive field step by step for each layer and enhance its local and semantic information. Finally, we design a more efficient loss function to predict the IOU between the prediction boxes and ground truth boxes, and the threshold IOU guides classification training and attenuates the scores, which are used by the NMS algorithm. Main Results: Benefiting from the above optimization, the proposed model PSSD achieves exciting performance in real-time. Specifically, with the hardware of Titan Xp and the input size of 320 pix, PSSD achieves 33.8 mAP at 45 FPS speed on MS COCO benchmark and 81.28 mAP at 66 FPS speed on Pascal VOC 2007 outperforming state-of-the-art object detection models. Besides, the proposed model performs significantly well with larger input size. Under 512 pix, PSSD can obtain 37.2 mAP with 27 FPS on MS COCO and 82.82 mAP with 40 FPS on Pascal VOC 2007. The experiment results prove that the proposed model has a better trade-off between speed and accuracy., Comment: We will submit it soon to the IEEE transaction. Due to characters limitation, we can not upload the full abstract. Please read the pdf file for more detail

We present a mm-scale optical fiber strain sensor to continuously measure the food deformation below the surface during the drying process. The sensor has a soft buffer sleeve, which enables a large measurable deformation range and minimizes the influence on the native food deformation. The sensor performance was investigated both theoretically and experimentally. To demonstrate the application in foods, we embedded the sensor inside fresh banana slices during a 4-hour-long air-drying process, where its wet basis moisture contents dropped from around 80% to 40%. The fiber sensor measurements covered the full normal strain of ~20% of the banana slices and revealed the shell-hardening characteristics in both the spatial and time dependences, by the comparison with the surface strains measured by the computer vision. Our work provides an unprecedented strain sensor that holds a high potential to contribute to improving both fundamental understandings and process monitoring of food drying processes.

This letter reports the design, construction, and experimental validation of a novel hand-held robot for in-office laser surgery of the vocal folds. In-office endoscopic laser surgery is an emerging trend in Laryngology: It promises to deliver the same patient outcomes of traditional surgical treatment (i.e., in the operating room), at a fraction of the cost. Unfortunately, office procedures can be challenging to perform; the optical fibers used for laser delivery can only emit light forward in a line-of-sight fashion, which severely limits anatomical access. The robot we present in this letter aims to overcome these challenges. The end effector of the robot is a steerable laser fiber, created through the combination of a thin optical fiber (0.225 mm) with a tendon-actuated Nickel-Titanium notched sheath that provides bending. This device can be seamlessly used with most commercially available endoscopes, as it is sufficiently small (1.1 mm) to pass through a working channel. To control the fiber, we propose a compact actuation unit that can be mounted on top of the endoscope handle, so that, during a procedure, the operating physician can operate both the endoscope and the steerable fiber with a single hand. We report simulation and phantom experiments demonstrating that the proposed device substantially enhances surgical access compared to current clinical fibers.