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16 results on '"Shergis, Johannah Linda"'

3. Effectiveness and Safety of Oral Cordyceps sinensis on Stable COPD of GOLD Stages 2–3: Systematic Review and Meta-Analysis

Author

Yu, Xuhua, Mao, Yuquan, Shergis, Johannah Linda, Coyle, Meaghan E., Wu, Lei, Chen, Yuanbin, Zhang, Anthony Lin, Lin, Lin, Xue, Charlie Changli, and Xu, Yinji

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Article Subject
Abstract

Cordyceps sinensis (CS) is a complementary medicine used for Chronic Obstructive Pulmonary Disease (COPD) of Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 2-3. Many randomized controlled trials have been conducted to evaluate the effect of CS alone or in combination with other herbs on stable COPD. To provide a synthesis of the evidence, we searched nine major electronic databases for randomized controlled trials on CS published before 21st December 2016. Fifteen interventional studies, including 1,238 participants, met the inclusion criteria. Meta-analysis showed that both CS preparations and CS formulae showed the potential benefits in lung function, exercise endurance, life quality, and improvement of symptoms. No serious adverse events were reported. So CS may be a promising treatment for patients with stable COPD of GOLD stages 2-3. No studies were placebo-controlled or of high methodological quality, which limits the conclusions.

Published
2019
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6. 12-month randomised controlled trial of ginseng extract for moderate COPD

Author

Shergis, Johannah Linda, primary, Thien, Francis, additional, Worsnop, Christopher John, additional, Lin, Lin, additional, Zhang, Anthony L, additional, Wu, Lei, additional, Chen, Yuanbin, additional, Xu, Yinji, additional, Langton, David, additional, Da Costa, Cliff, additional, Fong, Harry, additional, Wu, Darong, additional, Story, David, additional, and Xue, Charlie C, additional

Published
2019
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10. Safety of Chinese Herbal Medicine for Chronic Obstructive Pulmonary Disease

Author

Coyle, Meaghan, Shergis, Johannah Linda, Liu, Shaonan, Wu, Lei, Zhang, Anthony Lin, Guo, Xinfeng, Lu, Chuanjian, and Xue, Charlie Changli

Subjects
Article Subject
Abstract

Chinese herbal medicine (CHM) is increasingly used by patients with chronic obstructive pulmonary disease (COPD); however, there has been no systematic evaluation of its safety. This review examined the adverse events (AEs) reported in clinical studies of CHM for COPD. Five English databases (PubMed, Embase, CINAHL, AMED, and CENTRAL) and four Chinese databases (CBM, CNKI, CQVIP, and Wanfang Data) were searched from inception to May 2013. Adverse event data, including nature, severity, author-assigned causality, management, and outcome, were extracted from included studies. Descriptive statistics were used for the rate of adverse events. Of the 152 included studies, AEs were reported in 47 studies. The rate of adverse events was slightly lower in the CHM groups compared with controls (84 events in 5,909 participants, 1.4% versus 102 events in 5,676 participants, 1.8%). The most frequently reported adverse event was nausea (28 cases in the CHM groups and 19 cases in the control groups), which was more common in studies where CHM was combined with pharmacotherapy to treat acute exacerbation of COPD. Other frequent adverse events were abdominal discomfort, dry mouth, and dizziness. Detailed information about the adverse events was scant. Overall, CHM appears to be well tolerated in people with COPD.

Published
2015
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13. Natural products for chronic cough

Author

Shergis, Johannah Linda, primary, Wu, Lei, additional, May, Brian H, additional, Zhang, Anthony Lin, additional, Guo, Xinfeng, additional, Lu, Chuanjian, additional, and Xue, Charlie Changli, additional

Published
2015
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16. Acupuncture therapies for chronic obstructive pulmonary disease: a systematic review of randomized, controlled trials.

Author

Coyle, Meaghan Elizabeth, Shergis, Johannah Linda, Huang, Esther Tzu-Ya, Guo, Xinfeng, Di, Yuan Ming, Zhang, Anthony, and Xue, Charlie Changli

Abstract

Context · Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality and is projected to be the third leading cause of death by 2030. Acupuncture, a traditional Chinese therapy, has been used for more than 2000 years to treat respiratory conditions and may treat COPD effectively. In previous literature reviews, researchers have noted significant heterogeneity among the included studies, and none of the reviewers found convincing evidence to recommend routine use of acupuncture therapies for COPD. Objective · This literature review examined the efficacy and safety of acupuncture therapies for patients with COPD in improving lung function, increasing exercise capacity, creating positive subjective changes in symptoms, and enhancing health-related quality of life (QoL). Design · The research team searched the following electronic databases from inception to April 2013: PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL), the Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Allied and Complementary Medicine Database (AMED), Embase (Elsevier), the China National Knowledge Infrastructure (CNKI), Chongqing VIP Information Company (CQVIP), the Chinese Biomedical Literature Database (CBM), and Wanfang Data. The review included randomized, controlled trials (RCTs) that examined the benefits of acupuncture or other related therapies for treatment of COPD. Data were extracted into a predefined form; risk of bias was assessed according to the Cochrane Risk of Bias tool; and statistical analyses were made. Results · In total, 16 studies were included in the review. The research team found that the acupuncture therapies used in these studies improved health-related QoL. The team's conclusions, comparing results from the interventions with placebo, were based on data from 3 questionnaires that the studies used: (1) the St George's Respiratory Questionnaire (SGRQ), with a mean difference (MD) of -8.33 units (95% CI, -13.13 to -3.53); (2) dyspnea on the Medical Research Council's (MRC's) dyspnea scale, with an MD of -0.34 units (95% CI, -0.38 to -0.30); and (3) the Dyspnea Visual Analogue Scale (DVAS), with an MD of -8.85 mm (95% CI, -11.81 to -5.89). Compared with placebo, acupuncture therapies also increased the distance walked in 6 min (6MWT), with an MD of -28.14 (95% CI, 23.92 to 32.36) compared with placebo. No benefit was seen on measures of lung function when acupuncture therapies were compared with either placebo or drug therapy. Conclusion · Acupuncture therapies may result in clinically important improvements in QoL and dyspnea. Future high-quality RCTs should be undertaken to provide conclusive evidence concerning the benefits of acupuncture therapies in the treatment of COPD. [ABSTRACT FROM AUTHOR]

Published
2014

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