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Your search keyword '"Shi, Yulan"' showing total 33 results
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33 results on '"Shi, Yulan"'

2. A Method of On-Board Dynamic Health Management of TT&C Transponder of Spacecraft

Author

Zhang, Hongjun, Shi, Yulan, Wang, Shuai, Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin (Sherman), Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Guo, Qing, editor, Meng, Weixiao, editor, Jia, Min, editor, and Wang, Xue, editor

Published
2022
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21. Anti-damage effect of theaflavin-3′-gallate from black tea on UVB-irradiated HaCaT cells by photoprotection and maintaining cell homeostasis

Author

Haitao Wen, Meiyan Feng, Wenjing Pan, Xin Zheng, Juan Wan, Shi Yulan, Xinya Xie, Kunbo Wang, Shuxian Cai, Yingzi Wang, and Baozhu Hu

Subjects
Ultraviolet Rays, Photoaging, Cell, Biophysics, Apoptosis, Radiation-Protective Agents, Antioxidants, Catechin, chemistry.chemical_compound, Gallic Acid, Spectroscopy, Fourier Transform Infrared, medicine, Biflavonoids, HaCaT Cells, Homeostasis, Humans, Radiology, Nuclear Medicine and imaging, Cellular Senescence, Membrane Potential, Mitochondrial, Theaflavin-3-gallate, Radiation, Tea, integumentary system, Radiological and Ultrasound Technology, Chemistry, Gallate, medicine.disease, Intrinsic and extrinsic aging, Cell biology, HaCaT, medicine.anatomical_structure, Photoprotection, Spectrophotometry, Ultraviolet
Abstract

Keratinocytes are rich in lipids and are the main sensitive cells to ultraviolet (UV) rays. Theaflavins are the core functional components of black tea and are known as the "soft gold" in tea. In this study, ultraviolet-B (UVB) irradiation caused apoptosis and necrosis of human epidermal keratinocytes (HaCaT). EGCG and the four theaflavins had anti-UVB damage activity, among which theaflavin-3'-gallate (TF3'G) had the best activity. The results of biophysical and molecular biology experiments showed that TF3'G has anti-damage effects on UVB-irradiated HaCaT cells through the dual effects of photoprotection and maintenance of cell homeostasis. That is, TF3'G preincubation could absorb UV rays, reduce the accumulation of aging-related heterochromatin (SAHF) formation, increase mitochondrial membrane potential, downregulate NF-κB inflammation pathways, inhibit the formation of cytotoxic aggregates, and protect biological macromolecules Structure, etc. The accumulation of conjugated π bonds and the balance benzoquinone are the core functional structure of TF3'G with high efficiency and low toxicity. The study indicates that TF3'G has the potential to inhibit the photoaging and intrinsic aging of skin cells.

Published
2021

31. Pain management of pancreatic cancer patients with high-intensity focused ultrasound therapy.

Author

Shi Y, Ying X, Hu X, and Shen H

Subjects
Adult, Aged, Aged, 80 and over, Female, High-Intensity Focused Ultrasound Ablation methods, Humans, Male, Middle Aged, Pain Measurement methods, Treatment Outcome, Cancer Pain therapy, Pain Management methods, Pancreatic Neoplasms complications
Abstract

This study was performed to evaluate cancer pain control of high-Intensity focused ultrasound ablation (HIFU) and to manage the HIFU treatment pain in advanced pancreatic cancer patients with analgesics. We collected 71 locally advanced pancreatic cancer patients treated with HIFU from 2013 March to 2014 January in our hospital. The cancer pain (pre-HIFU and two weeks after HIFU) and HIFU treatment pain were evaluated respectively. The numeric rating scale (NRS) was used as the tool of pain evaluation. The related factors with pains were analyzed. The 70.42% cancer painless rate before HIFU was improved to 92.96% (P<0.05) 2 weeks after HIFU in 71 advanced pancreatic cancer patents without analgesics adjustment. The HIFU treatment pain occurred in 42 of 71 treated patients (59.15 %). The average duration was 3.93 days and pain score was 3.22. HIFU can improve cancer pain relief further in the advanced pancreatic cancer patients with third ladder analgesics, meanwhile HIFU treatment pain can be managed easy because of its short duration and low pain score.

Published
2017

32. Influence of high intensity focused ultrasound (HIFU) treatment to the pancreatic function in pancreatic cancer patients.

Author

Shi Y, Ying X, Hu X, Zhao J, Fang X, Wu M, Chen TZ, and Shen H

Subjects
Adult, Aged, Amylases blood, Biomarkers blood, Blood Glucose metabolism, Female, Humans, Islets of Langerhans pathology, Islets of Langerhans physiopathology, Male, Middle Aged, Neoplasm Staging, Pancreas, Exocrine pathology, Pancreas, Exocrine physiopathology, Pancreatic Neoplasms blood, Pancreatic Neoplasms pathology, Pancreatic Neoplasms physiopathology, Pancreatitis blood, Pancreatitis etiology, Patient Safety, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, High-Intensity Focused Ultrasound Ablation adverse effects, Islets of Langerhans metabolism, Pancreas, Exocrine metabolism, Pancreatic Neoplasms therapy
Abstract

Present study was designed to investigate the pancreatic endocrine and exocrine function damage after High Intensity Focused Ultrasound (HIFU) therapy in patients with advanced pancreatic cancer. It was a retrospective analysis of blood glucose and amylase changes in 59 advanced pancreatic cancer patients treated with HIFU from 2010 February to 2014 January. The mean glucose and amylase before HIFU treatment were 6.02mmol/L and 59.17 U/L respectively. After HIFU treatment, it was shown that the mean glucose and amylase levels were 5.66mmol/L and 57.86/L respectively. There was no statistical significance between them. No acute pancreatitis was observed. The endocrine and exocrine function of pancreatic cancer patients was not damaged by HIFU treatment. HIFU treatment for the pancreatic cancer patients seems to be safe.

Published
2015

33. Erythropoietin protects primary cultures of rat cortical neurons from hypoxia-induced toxicity through attenuating both glutamate release and NMDA receptor evoked neurotoxicity pathway.

Author

Xu X, Dai H, and Shi Y

Subjects
Animals, Cell Survival drug effects, Cells, Cultured, Cerebral Cortex drug effects, Glutamic Acid toxicity, Humans, Rats, Rats, Sprague-Dawley, Recombinant Proteins, Signal Transduction drug effects, Cell Hypoxia drug effects, Cerebral Cortex cytology, Erythropoietin pharmacology, Glutamic Acid metabolism, Neurons drug effects, Neuroprotective Agents, Neurotoxicity Syndromes pathology, Receptors, N-Methyl-D-Aspartate drug effects
Abstract

Aim: To investigate the neuroprotective effect of EPO against hypoxia, and determine the mechanism with respect to the EPO-induced neuroprotection., Methods: Experiments were conducted using primary neuron cultures. Neuron survival and glutamate release were measured after bein insulted by hypoxia. Glutamate concentrations were determined by an HPLC-ECD system., Results: Neurons were significantly damaged in hypoxia. Application of recombinant human EPO (10(-11) M) within 24 h before hypoxia significantly increased neuronal survival compared with no EPO treatment. Moreover, the enhancing of glutamate release stimulated by hypoxia was inhibited by pretreatment with EPO at a concentration of 10(-11) M. Further studies demonstrated that EPO also prevented glutamate and NMDA insulted neurotoxicity., Conclusion: These findings suggest that EPO prevents neuronal death in the cultured cortical neuron, possibly through attenuating both glutamate release and NMDA receptor evoked neurotoxicity pathway.

Published
2009

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