1. An Empirical Model for Describing the Small Field Penumbra in Radiation Therapy
- Author
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Jia-Ming Wu, Shi-Qiang Tang, and Yee-Min Jen
- Subjects
Article Subject ,Dose profile ,lcsh:Medicine ,Empirical Research ,Curvature ,General Biochemistry, Genetics and Molecular Biology ,Imaging phantom ,Linear particle accelerator ,030218 nuclear medicine & medical imaging ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Quadratic equation ,law ,Penetration depth ,Physics ,General Immunology and Microbiology ,Phantoms, Imaging ,Penumbra ,Radiotherapy Planning, Computer-Assisted ,Mathematical analysis ,lcsh:R ,Collimator ,Dose-Response Relationship, Radiation ,Radiotherapy Dosage ,General Medicine ,030220 oncology & carcinogenesis ,Calibration ,Regression Analysis ,Research Article - Abstract
Purpose. We developed a mathematic empirical model for describing the small field penumbra in order to analyze the potential dose perturbation caused by overlapping field to avoid the dose calculation errors in linear accelerator-based radiosurgery. Materials and methods. A ball phantom was fabricated for measuring penumbra at 4 different gantry angles in the coplanar plane. A least square root estimation (LSRE) Model was created to fit the measured penumbra dose profile and to predict the penumbra dose profile at any gantry angles. The Sum of Squared Errors (SSE) was used for finding the parameters n and t for the best fitting of the LSRE model. Geometric and mathematical methods were used to derive the model parameters. Results. The results showed that the larger the gantry angle of the field, the more the expansion of the penumbra dose profile. The least square root estimation model for describing small field penumbra is as follows: PenumbraDš=T⋅1/2⋅1−š/n+š2+t where PenumbraDš denotes the dose profile D(š) at the penumbra region, T is the penumbra height (usually in scalar 100), n is the parameter for curvature, š = x − Wd/2 (x and š are the values in cm on x-axis), and t is the radiation transmission of the collimator. Geometric analysis establishes the correlation between the penetration depth of the exposure and its effect on the penumbra region in ball phantom. The penumbra caused by an exposure at any arbitrary angles can be geometrically derived by using a one-variable quadratic equation. Conclusion. The dose distribution in penumbra region of small field can be created by the LSRE model and the potential overdosage or underdosage owing to overlapping field perturbation can be estimated.
- Published
- 2019
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