158 results on '"Shirakawa, Ryutaro"'
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2. Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production
3. Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation
4. Protective effects of Mkl1/2 against lipodystrophy and muscle atrophy via PI3K/AKT-independent FoxO repression
5. Human CTL-based functional analysis shows the reliability of a munc13-4 protein expression assay for FHL3 diagnosis
6. Platelet αIIbβ3 integrin binds to SARS-CoV-2 spike protein of alpha strain but not wild type and omicron strains
7. Inhibitor of Growth 4 (ING4) is a positive regulator of rRNA synthesis
8. Endogenous APOBEC3B Overexpression Constitutively Generates DNA Substitutions and Deletions in Myeloma Cells
9. A CD57+ CTL Degranulation Assay Effectively Identifies Familial Hemophagocytic Lymphohistiocytosis Type 3 Patients
10. Prostaglandin E2 inhibits neutrophil extracellular trap formation through production of cyclic AMP
11. Ral GTPase–activating protein regulates the malignancy of pancreatic ductal adenocarcinoma
12. Ral GTPases: crucial mediators of exocytosis and tumourigenesis
13. Familial hemophagocytic lymphohistiocytosis with the MUNC13-4 mutation: a case report
14. Double prenylation of SNARE protein Ykt6 is required for lysosomal hydrolase trafficking
15. A SNARE geranylgeranyltransferase essential for the organization of the Golgi apparatus
16. APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression
17. APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression
18. Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions
19. Purification and Functional Analysis of a Rab27 Effector Munc13‐4 Using a Semiintact Platelet Dense‐Granule Secretion Assay
20. Crystal structure of human DAAM1 formin homology 2 domain
21. Elucidation of the molecular mechanism of platelet activation: Dense granule secretion is regulated by small guanosine triphosphate-binding protein Rab27 and its effector Munc13-4
22. Double prenylation of SNARE protein Ykt6 is required for lysosomal hydrolase trafficking.
23. Downregulation of RalGTPase-activating protein promotes invasion of prostatic epithelial cells and progression from intraepithelial neoplasia to cancer during prostate carcinogenesis
24. Su1808 – Downregulation of Ralgtpase-Activating Protein Leads to Exacerbation of Murine Dextran Sulfate Sodium-Induced Colitis
25. C2 Domains of Munc13-4 Are Crucial for Ca2+-Dependent Degranulation and Cytotoxicity in NK Cells
26. Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity
27. A CD57+ CTL Degranulation Assay Effectively Identifies Familial Hemophagocytic Lymphohistiocytosis Type 3 Patients
28. Prostaglandin E2inhibits neutrophil extracellular trap formation through production of cyclic AMP
29. Platelets Are Highly Activated in Patients of Chronic Thromboembolic Pulmonary Hypertension
30. The antimalarial drugs chloroquine and primaquine inhibit pyridoxal kinase, an essential enzyme for vitamin B6 production
31. GARNL1, a major RalGAP α subunit in skeletal muscle, regulates insulin-stimulated RalA activation and GLUT4 trafficking via interaction with 14-3-3 proteins
32. Munc13 - 4 ワ GTPガタ Rab27 ケツゴウ タンパクシツ デ アリ ケッショウバン ノウセン カリュウ ブンピ オ セイギョスル
33. Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
34. Impact of Platelet Reactivity on Long-term Clinical Outcomes and Bleeding Events in Japanese Patients Receiving Antiplatelet Therapy with Aspirin
35. Effects of PPIs and an H2 blocker on the Antiplatelet Function of Clopidogrel in Japanese Patients under Dual Antiplatelet Therapy
36. Rab-genome analysis reveals novel insights in Weibel-Palade body exocytosis
37. Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein
38. Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocyte differentiation
39. Flightless-I (Fli-I) Regulates the Actin Assembly Activity of Diaphanous-related Formins (DRFs) Daam1 and mDia1 in Cooperation with Active Rho GTPase
40. Characterization of the Antiplatelet Effect of Aspirin at Enrollment and After 2-Year Follow-up in a Real Clinical Setting in Japan
41. Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPases
42. Biochemical Characterization of the Rho GTPase-regulated Actin Assembly by Diaphanous-related Formins, mDia1 and Daam1, in Platelets
43. Evaluation of the Antiplatelet Effects of Cilostazol, a Phosphodiesterase 3 Inhibitor, by VASP Phosphorylation and Platelet Aggregation
44. Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway
45. Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity
46. Molecular mechanism of platelet granule secretion
47. Constitutive GDP/GTP Exchange and Secretion-dependent GTP Hydrolysis Activity for Rab27 in Platelets
48. 1P358 Structural analysis of the Mammalian Exocyst Complex(13. Membrane transport,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
49. 1P304 Crystal structure of Formin Homology 2 domain of human DAAM1(10. Cytoskeleton,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
50. 1P357 Crystal structure of yeast Sec2p, a guanine nucleotide exchange factor for yeast Rab GTPase, Sec4p(13. Membrane transport,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
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