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16 results on '"Shiva-Kumar, Prithvi"'

2. Isosorbide Dinitrate, With or Without Hydralazine, Does Not Reduce Wave Reflections, Left Ventricular Hypertrophy, or Myocardial Fibrosis in Patients With Heart Failure With Preserved Ejection Fraction.

Author

Zamani, Payman, Akers, Scott, Soto‐Calderon, Haideliza, Beraun, Melissa, Koppula, Maheswara R., Varakantam, Swapna, Rawat, Deepa, Shiva‐Kumar, Prithvi, Haines, Philip G., Chittams, Jesse, Townsend, Raymond R., Witschey, Walter R., Segers, Patrick, Chirinos, Julio A., Soto-Calderon, Haideliza, and Shiva-Kumar, Prithvi

Published
2017
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3. Aortic arch anatomy is a strong correlate of arterial wave reflections in systolic heart failure

Author

Cherukumalli, Nishitha, primary, Tariq, Ali, additional, Vadde, Neetha, additional, Zamani, Payman, additional, Dunde, Anjaneyulu, additional, Desai, Sanjal, additional, Sharabu, Chandrahasa, additional, Konda, Prasad, additional, Rawat, Deepa, additional, Shiva-Kumar, Prithvi, additional, Segers, Patrick, additional, Akers, Scott, additional, and Chirinos, Julio A., additional

Published
2015
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4. Resistive and pulsatile arterial load are similar in well-treated black vs. white subjects with HFrEF

Author

Vadde, Neetha, primary, Tariq, Ali, additional, Dunde, Anjaneyulu, additional, Cherukumalli, Nishitha, additional, Zamani, Payman, additional, Akers, Scott, additional, Konda, Prasad, additional, Bhuva, Rushik, additional, Shiva-Kumar, Prithvi, additional, Peddireddy, Shivapriya, additional, Segers, Patrick, additional, and Chirinos, Julio A., additional

Published
2015
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5. Experimental and Mathematical Analyses Relating Circadian Period and Phase of Entrainment in Neurospora crassa.

Author

Lee, Kwangwon, Shiva Kumar, Prithvi, McQuade, Sean, Lee, Joshua Y., Park, Sohyun, An, Zheming, and Piccoli, Benedetto

Subjects
*CIRCADIAN rhythms, *PHENOTYPES, *NEUROSPORA crassa, *THIOREDOXIN, *MATHEMATICAL analysis
Abstract

Circadian rhythms are observed in most organisms on earth and are known to play a major role in successful adaptation to the 24-h cycling environment. Circadian phenotypes are characterized by a free-running period that is observed in constant conditions and an entrained phase that is observed in cyclic conditions. Thus, the relationship between the free-running period and phase of entrainment is of interest. A popular simple rule has been that the entrained phase is the expression of the period in a cycling environment (i.e., that a short period causes an advanced phase and a long period causes a delayed phase). However, there are experimental data that are not explained by this simple relationship, and no systematic study has been done to explore all possible period-phase relationships. Here, we show the existence of stable period-phase relationships that are exceptions to this rule. First, we analyzed period-phase relationships using populations with different degrees of genome complexity. Second, we generated isogenic F1 populations by crossing 14 classical period mutants to the same female and analyzed 2 populations with a short period/delayed phase and a long period/advanced phase. Third, we generated a mathematical model to account for such variable relationships between period and phase. Our analyses support the view that the circadian period of an organism is not the only predictor of the entrained phase. [ABSTRACT FROM AUTHOR]

Published
2017
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6. Effect of Inorganic Nitrate on Exercise Capacity in Heart Failure With Preserved Ejection Fraction

Author

Zamani, Payman, primary, Rawat, Deepa, additional, Shiva-Kumar, Prithvi, additional, Geraci, Salvatore, additional, Bhuva, Rushik, additional, Konda, Prasad, additional, Doulias, Paschalis-Thomas, additional, Ischiropoulos, Harry, additional, Townsend, Raymond R., additional, Margulies, Kenneth B., additional, Cappola, Thomas P., additional, Poole, David C., additional, and Chirinos, Julio A., additional

Published
2015
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9. Effective Arterial Elastance Is Insensitive to Pulsatile Arterial Load

Author

Chirinos, Julio A., primary, Rietzschel, Ernst R., additional, Shiva-Kumar, Prithvi, additional, De Buyzere, Marc L., additional, Zamani, Payman, additional, Claessens, Tom, additional, Geraci, Salvatore, additional, Konda, Prasad, additional, De Bacquer, Dirk, additional, Akers, Scott R., additional, Gillebert, Thierry C., additional, and Segers, Patrick, additional

Published
2014
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10. DIFFUSE MYOCARDIAL FIBROSIS IS GREATLY ELEVATED IN MALES WITH HEART FAILURE WITH REDUCED EJECTION FRACTION, BUT NOT HEART FAILURE WITH PRESERVED EJECTION FRACTION

Author

Desai, Sanjal, primary, Haines, Philip, additional, Zamani, Payman, additional, Konda, Prasad, additional, Shiva-Kumar, Prithvi, additional, Peddireddy, Shivapriya, additional, Shekhar, Rahul Chandra, additional, Jain, Snigdha, additional, kers, Scott, additional, Ferrari, Victor, additional, and Chirinos, Julio, additional

Published
2014
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11. Abstract 18641: Relationship Between Effective Arterial Elastance and Specific Measures of Left Ventricular Afterload

Author

Chirinos, Julio, primary, Shiva-Kumar, Prithvi, additional, Geraci, Salvatore, additional, Desai, Sanjal, additional, Chandrashekhar, Rahul, additional, Jain, Snigdha, additional, Saif, Hassam, additional, Haines, Philip, additional, Broderick, Preston, additional, Vakilipour, Amin, additional, Rawat, Deepa, additional, Witschey, Walter, additional, Ferrari, Victor, additional, and Akers, Scott, additional

Published
2013
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12. Abstract 18304: Assessment of Age-Related Aortic Stiffness With Magnetic Resonance Imaging

Author

Chirinos, Julio, primary, Shiva-Kumar, Prithvi, additional, Chandrashekhar, Rahul, additional, Desai, Sanjal, additional, Witschey, Walter, additional, Jain, Snigdha, additional, Saif, Hassam, additional, Haines, Philip, additional, Broderick, Preston, additional, Geraci, Salvatore, additional, Vakilipour, Amin, additional, Rawat, Deepa, additional, Ferrari, Victor, additional, and Akers, Scott, additional

Published
2013
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13. TIME-RESOLVED LEFT VENTRICULAR MYOCARDIAL STRESS IN HEART FAILURE WITH REDUCED EJECTION FRACTION REVEALS A MARKED INCREASE IN LATE SYSTOLIC MYOCARDIAL LOAD

Author

Chandrashekhar, Rahul, primary, Akers, Scott, additional, Vakilipour, Amin, additional, Shiva-Kumar, Prithvi, additional, Haines, Philip, additional, Jain, Snigdha, additional, Saif, Hassam, additional, Witschey, Walter, additional, Ferrari, Victor A., additional, and Chirinos, Julio A., additional

Published
2013
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16. Prospective Risk Factors for Increased Central Augmentation Index in Men and Women.

Author

Shiva Kumar, Prithvi, Medina-Lezama, Josefina, Morey-Vargas, Oscar, Zamani, Payman, Bolaños-Salazar, Juan F., Chirinos, Diana A., Haines, Philip, Khan, Zubair A., Coacalla-Guerra, Johanna C., Davalos-Robles, Maria E., Llerena-Dongo, Gladys R., Zapata-Ponze, Mardelangel, and Chirinos, Julio A.

Subjects
ARTERIAL diseases, BLOOD pressure, HIGH-density lipoprotein receptors, CHOLESTEROL, HEART rate monitoring
Abstract

BACKGROUND Arterial wave reflections are important determinants of central pressure pulsatility and left ventricular afterload. The augmentation index (AIx) is the most widely used surrogate of arterial wave reflections. Despite multiple cross-sectional studies assessing the correlates of AIx, little prospective data exist regarding changes in AIx over time. We aimed to assess the predictors of changes in AIx over time in adults from the general population. METHODS We performed radial arterial tonometry assessments a median of 3.18±0.4 years apart on 143 nondiabetic adult participants in the population-based PREVENCION study. Central AIx was obtained using the generalized transfer function of the Sphygmocor device. RESULTS Predictors of the change in AIx over time were investigated. Among men (n = 67), the change in AIx was predicted by abdominal obesity (standardized β for waist circumference = 0.34; P = 0.002), impaired fasting glucose (standardized β = 0.24; P = 0.009), and the change in heart rate (standardized β = −0.78; P < 0.001). Among women (n = 76), the change in AIx was predicted by non–high-density lipoprotein cholesterol (standardized β = 0.33; P = 0.001), C-reactive protein levels (standardized β = 0.24; P = 0.02), change in mean arterial pressure (standardized β = 0.33; P = 0.001), and change in heart rate (standardized β = −0.52; P < 0.001). CONCLUSIONS Metabolic and inflammatory factors predicted changes in AIx over time, with important sex differences. Metabolic factors, such as abdominal obesity and impaired fasting glucose, predicted changes in AIx in men, whereas C-reactive protein and non–high-density lipoprotein cholesterol levels predicted changes in women. Our findings highlight the impact of sex on arterial properties and may guide the design of interventions to favorably impact changes in late systolic pressure augmentation. [ABSTRACT FROM PUBLISHER]

Published
2015

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