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International communication has become more and more frequent in recent societies, but misunderstandings and miscommunication due to stereotypes inevitably exist in cross-cultural exchanges. Therefore, this paper would analyze the live-action film Mulan, a Chinese story told by Disney that reflects the stereotypes of Chinese culture from the Western perspective. Due to the cultural differences between China and the U.S. (such as the different pursuit of individualism and collectivism), the filmmakers’ misunderstanding of the story, especially the important plot of Mulan replacing her father in the army, Disney sets the core viewpoint of the story as Mulan pursuing proving herself, instead of the traditional Chinese culture’s understanding that Mulan makes the decision to take her father’s place in the army for the sake of her family and the country’s collective interests. There are many other stereotypes in the film, these stereotypes have caused dissatisfaction of Chinese audiences with the film. The paper gives some suggestions to improve the acceptance of cross-cultural film and television works in the local market, like investors can choose local market cultural figures as the film’s main producer. The film producer should be rigorous in the examination of local culture and it is better to choose the local language for the dubbing of cross-cultural films. This paper profoundly analyzes the situations and causes of misunderstandings and deviations in cross-cultural communication and provides suggestions, which to a certain extent improves the efficiency of cross-cultural communication and cross-cultural film and television production in future.

Deoxynivalenol (DON) is widely emerging in various grain crops, milk, and wine products, which can trigger different toxic effects on humans and animals by inhalation or ingestion. It also imposes a considerable financial loss on the agriculture and food industry each year. Previous studies have reported acute and chronic toxicity of DON in liver, and liver is not only the main detoxification organ for DON but also the circadian clock oscillator directly or indirectly regulates critical physiologically hepatic functions under different physiological and pathological conditions. However, researches on the association of circadian rhythm in DON-induced liver damage are limited. In the present study, mice were divided into four groups (CON, DON, Bmal1

The paper demonstrates the CFD capability to predict the effect of rod bowing on CHF. The applicability and performance of the models are validated based on the Weatherhead experimental data for vertical pipe and NUPEC PWR subchannel and bundle test (PSBT) International Benchmark for rod bundle. The capability of the existing CFD method in predicting CHF is studied both qualitatively and quantitatively. Based on the validated method, the effect of the bowed rod on CHF is evaluated. The bow is assumed to occur at the midspan between two spacer grids in the region where DNB is predicted to occur. The results indicate that rod bowing has a deleterious effect on CHF, but this adverse bowing effect is dependent on the closure (i.e., the ratio of the change of the fuel rod gap to the nominal gap). There is no effect on CHF for closure between 0 and 50%, but adverse effect on CHF for closure larger than 50%, even more considerable effect as the closure increases to larger than 85%. The findings can be used to assist in designing the test fuel rod before the rod bowing CHF experiment.

Grid-to-rod fretting (GTRF) caused by flow induced vibration is one of the most important mechanisms of fuel rod failure in PWRs, which has a strong impact on the economy and safety of nuclear power plant. To avoid rod failure due to GTRF, several verification tests which are high costs and long term are always carried out for new design fuel assemblies. So as to deal with the disadvantages of tests and speed up progress in fuel design, a progressive analysis method to predict GTRF performance of fuel rod is developed, and systemic tests are carried out to verify the analysis method. The method consists of three main parts, including flow field analysis, structure vibration analysis and wear analysis. In the first part, the flow field excitation force is obtained by the large eddy simulation method, and this CFD method is verified by a particle image velocimetry (PIV) test with a 5 × 5 fuel bundle. In the second part, to get the vibration response of fuel rod, a nonlinear vibration model which can consider end-of-life gaps is established. Full scale fuel rod vibration in air and water conditions are tested to validate the predicted fuel rod response from analysis. In the third part, the fuel rod wear is estimated by tribological theory with fuel rod vibration response, the wear coefficient and the typical feature of wear scar. The GTRF method is finally verified by a long-term wear test of full-scale fuel assembly. It turns out that this method can effectively predict the wear characteristics of fuel rod cladding at the early stage of design. It provides a feasible solution for rapid design iteration of fuel assembly, and could reduce the development costs and risks.

As the core component and the first safety barrier of a nuclear power plant, the structural integrity of fuel assemblies (FAs) is an important factor in ensuring the safety of nuclear power. Safety analysis and evaluation of fuel assemblies under seismic conditions is a requirement of nuclear power plant design codes and safety reviews. The mechanical properties of a single FA determine the operational and seismic performance of the core fuel assembly. Due to the complexity of the FAs in terms of structure and boundary conditions, test is the most common method to obtain the mechanical properties. In order to predict the mechanical properties of the fuel assembly, a nonlinear finite element detailed model was developed. The contact and frictional behavior between the fuel rod cladding and the spring/dimple convexity were considered in the modeling to simulate the nonlinear behavior of the fuel rod better. To verify the validity of the model, virtual tests of lateral stiffness test, forced vibration test and impact test were conducted on the model. The comparison with the experimental results shows that the model can reflect the mechanical properties of the fuel assembly well. The modeling method and calculation conclusions in this paper are of guidance for fuel assembly design.

The top nozzle is an important part of the fuel assembly and is located at the core coolant outlet, which has an important impact on the uniformity of the coolant flow distribution at the core outlet and the overall pressure drop of the fuel assembly[1]. The peak stress of the top nozzle under each working condition appears at the position of the adapter plate, top nozzle and the pressure drop of the top nozzle is closely related to the flow area, height and local characteristics of the adapter plate. In this paper, the overall structure of the adapter plate is optimized to reduce the pressure drop as much as possible on the premise of ensuring that the stress meets the requirements of the standard limit. The 3D modeling software NX is used to establish the geometric model of the top nozzle, and it is transferred to ANSYS to establish a finite element model for simulation optimization design. On this basis, the key dimension parameters of the adapter plate (such as the thickness of the rib, etc.) are selected as design variables, and the law of its influence on the blocking area and stress is studied, and the structure size is further optimized.

In this study, a new experimental method for photon unfolding spectroscopy of protein ions based on a Fourier transform ion cyclotron resonance (FT ICR) mass spectrometer was developed. The method of short-time Fourier transform has been applied here to obtain decay curves of target ions trapped in the cell of the FT ICR mass spectrometer. Based on the decay constants, the collision cross sections (CCSs) of target ions were calculated using the energetic hard-sphere model. By combining a tunable laser to the FT ICR mass spectrometer, the changes of CCSs of the target ions were recorded as a function of the wavelengths; thus, the photon isomerization spectrum was obtained. As one example, the photon isomerization spectrum of [Cyt c + 13H]13+ was recorded as the decay constants relative to the applied wavelengths of the laser in the 410–480 nm range. The spectrum shows a maximum at 426 nm, where an unfolded structure induced by a 4 s irradiation can be deduced. The strong peak at 426 nm was also observed for another ion of [Cyt c + 15H]15+, although some difference at 410 nm between the two spectra was found at the same time. This novel method can be expanded to ultraviolet or infrared region, making the experimental study of wavelength-dependent photon-induced structural variation of a variety of organic or biological molecules possible.

Allicin, a thiosulfonate extract from freshly minced garlic, has been reported to have various biological effects on different organs and systems of animals and human. It can reduce oxidative stress, inhibit inflammatory response, resist pathogen infection and regulate intestinal flora. In addition, dozens of studies also demonstrated allicin could reduce blood glucose level, protect cardiovascular system and nervous system, and fight against cancers. Allicin was widely used in disease prevention and health care. However, more investigations on human cohort study are needed to verify the biological or clinical effects of allicin in the future. In this review, we summarized the biological effects of allicin from previous outstanding and valuable studies and provided useful information for future studies on the health effects of allicin.

Whey protein has been reported to be an impactful dietary supplement to ameliorate skeletal muscle aging for a long time. However, whether whey protein could contribute to muscle aging amelioration by post-transcriptional modulation remains unclear. In this study, 19-month-old mice orally received whey protein supplementation (1.0 g/kg/bw/d, whey protein group) or deionized water (the control group) for 3 months. Differentially expressed ncRNAs and mRNAs in quadriceps were identified by RNA-seq. Construction of non-coding RNAs (ncRNAs)-associated competing endogenous RNA (ceRNA) networks as well as GO and KEGG enrichment analyses were also carried out subsequently. Meanwhile, ultrasound measurement, HE staining, myofiber cross-sectional area measurement, western blotting and RT-qPCR were performed in the quadriceps to evaluate muscle status and verify the RNA-seq data. Whey protein supplementation for 3 months increased quadriceps-body weight ratio and improved the histological as well as ultrasonographic characteristics of aging in muscle. Moreover, the protein expression levels of Myog, Myf4, Myf5 and MyoD1 were all significantly elevated in quadriceps. The expression of 90 lncRNAs, 334 mRNAs, six circRNAs and 52 miRNAs were significantly up or down-regulated in quadriceps after whey protein supplementation. Furthermore, ncRNAs-associated networks and GO and KEGG enrichment analyses revealed whey protein may influence muscle aging process through selected ncRNAs-associated ceRNA networks. Therefore, post-transcriptional modulation could be a potential crucial way to ameliorate skeletal muscle aging after whey protein supplementation. The selected ncRNAs-associated ceRNA networks may provide new insight for the underlying mechanism and profound therapeutic target for skeletal muscle aging.

Exposure of humans to parabens is widespread and urinary parabens are widely used as exposure biomarkers. However, are the levels of these chemicals suitable to assess exposure to parabens? We conducted an intervention study by controlling the use of personal care products (PCPs) to explore the exposure of parabens. Ten female participants were recruited who were treated with different types of PCPs during the 18-day study period. The concentrations of parabens and their metabolites in matrices of different exposure pathways (dust, drinking water and dietary food) and urine samples were determined. We demonstrated that PCPs were the major sources of parabens, accounting for >99% of total exposure. The metabolites were nonspecific to individual parabens and could not be used as exposure biomarkers. Urinary paraben concentrations were positively correlated with external exposure levels. However, poor reproducibility was observed, with intraclass correlation coefficients (ICC) ranging from 0.125 to 0.295 in unadjusted urinary concentrations. Creatinine-adjusting could not significantly improve the ICC values in random spot samples. After adjusting for both creatinine and kinetic models, the ICC values ranged from 0.695 to 0.886, indicating a good reproducibility. So, toxicokinetic parameters may be taken into consideration for precise monitoring of exposures for the non-persistent pollutants.

Cultural trauma appears when a collectivity of human beings suffers sudden and rapid social change, touching the core of their inner sense. This paper analyzes cultural trauma in the precise time in that novel according to a classification of the Cultural Trauma theory and presents various strategies to cope with trauma. The whole process of cultural trauma reveals the complicated background then. Confronting ethic problems in displacement, tackling pertinent issues of the globalizing world and struggling with the lingering colonial effects of Britain in India, the novel depicts a special historical scene, implying the ways of living and enlightening today’s loss during the period of inheritance.

In this paper, periodic and hybrid trichiral structure is developed as the raft in a floating raft system to enhance isolation performance in the medium and high-frequency range. Firstly, wave propagation in the periodic trichiral structure is analyzed through Bloch theorem. Further study of the hybrid trichiral structure, consisting of multilayer of cells with different geometry, demonstrates that the stop band of this assembly is the superposition of the band gap generated by individual cells. This feature can be used to extend the stop band without affecting the performance in other frequencies. Vibration transmission of the floating raft system is studied through frequency response function based substructuring method. Numerical examples indicate that the sound power radiated from the foundation can be greatly attenuated in the stop band of the periodic trichiral raft. Based on the feature of hybrid structure, an optimization scheme with respect to the trichiral raft is developed with the aim of minimizing the radiated sound power of the system. The proposed modeling and optimization method can be extended to design other regular raft structures with great flexibility.

A hybrid material of indium tin-oxide (ITO) wrapped titanium dioxide and reduced graphene oxide (ITO-rGO and TiO2) was prepared using a facile hydrothermal technique. TiO2 nanorods were in situ grown on the surface of rGO (rGO and TiO2), and which was then assembled onto ITO substrate layer by layer with formation of a 3D structure. ITO-rGO and TiO2 exhibit low charge transfer resistance at the electrode-electrolyte interface and have good photoresponsive ability. Methylene blue (MB) can be effectively adsorbed and enriched onto ITO-rGO and TiO2 surface. The adsorption kinetics and thermodynamics of ITO-rGO and TiO2 were evaluated, showing that the exothermic and entropy-driven reaction were the main thermodynamic processes, and the Langmuir isotherm was the ideal model for adsorption fitting. Meanwhile, ITO greatly improved degradation of rGO and TiO2 because electrons can be collected by ITO before recombination and MB can easily enter into the 3D structure of rGO and TiO2. The highest photodegradation rate of MB reached 93.40% for ITO-rGO and TiO2 at pH 9. Additionally, ITO-rGO and TiO2 successfully solved the problems of being difficult to recycle and causing secondary pollution of traditional TiO2 catalysts. Therefore, ITO-rGO and TiO2 may be a potential photocatalyst for degrading organic pollutants in water.

The Bloch theorem and finite element technique are applied to investigate the bandgap property of trigonal chiral cellular, which is illustrated through band diagrams. The finite element model is developed to validate the results. Vibration transmission displays significant attenuation for the frequency located in the band gap. The distribution of the band gap is determined by the geometry of the unit cell and can be tuned to specific frequency range. Attention is devoted to the dependence of phase speed and group velocity on frequency and direction, which provides important information about anisotropic wave behavior of the structure and shows existence of preferential directions of propagation and energy flow. The research outcomes will lay a solid theoretical base for the designing of chiral isolation structures.