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3. Anticoagulation Strategies in Non–Critically Ill Patients with Covid-19

Author

McQuilten, Zoe K., primary, Venkatesh, Balasubramanian, additional, Jha, Vivekanand, additional, Roberts, Jason, additional, Morpeth, Susan C., additional, Totterdell, James A., additional, McPhee, Grace M., additional, Abraham, John, additional, Bam, Niraj, additional, Bandara, Methma, additional, Bangi, Ashpak K., additional, Barina, Lauren A., additional, Basnet, Bhupendra K., additional, Bhally, Hasan, additional, Bhusal, Khema R., additional, Bogati, Umesh, additional, Bowen, Asha C., additional, Burke, Andrew J., additional, Christopher, Devasahayam J., additional, Chunilal, Sanjeev D., additional, Cochrane, Belinda, additional, Curnow, Jennifer L., additional, Das, Santa Kumar, additional, Dhungana, Ashesh, additional, Di Tanna, Gian Luca, additional, Dotel, Ravindra, additional, DSouza, Hyjel, additional, Dummer, Jack, additional, Dutta, Sourabh, additional, Foo, Hong, additional, Gilbey, Timothy L., additional, Giles, Michelle L., additional, Goli, Kasiram, additional, Gordon, Adrienne, additional, Gyanwali, Pradip, additional, Haksar, Dipak, additional, Hudson, Bernard J., additional, Jani, Manoj K., additional, Jevaji, Purnima R., additional, Jhawar, Sachin, additional, Jindal, Aikaj, additional, John, M. Joseph, additional, John, Mary, additional, John, Flavita B., additional, John, Oommen, additional, Jones, Mark, additional, Joshi, Rajesh D., additional, Kamath, Prashanthi, additional, Kang, Gagandeep, additional, Karki, Achyut R., additional, Karmalkar, Abhishek M., additional, Kaur, Baldeep, additional, Koganti, Kalyan Chakravarthy, additional, Koshy, Jency M., additional, Krishnamurthy, Mathew S., additional, Lau, Jillian S., additional, Lewin, Sharon R., additional, Lim, Lyn-li, additional, Marschner, Ian C., additional, Marsh, Julie A., additional, Maze, Michael J., additional, McGree, James M., additional, McMahon, James H., additional, Medcalf, Robert L., additional, Merriman, Eileen G., additional, Misal, Amol P., additional, Mora, Jocelyn M., additional, Mudaliar, Vijaybabu K., additional, Nguyen, Vi, additional, O’Sullivan, Matthew V., additional, Pant, Suman, additional, Pant, Pankaj, additional, Paterson, David L., additional, Price, David J., additional, Rees, Megan A., additional, Robinson, James O., additional, Rogers, Benjamin A., additional, Samuel, Sandhya, additional, Sasadeusz, Joe, additional, Sharma, Deepak, additional, Sharma, Prabhat K., additional, Shrestha, Roshan, additional, Shrestha, Sailesh K., additional, Shrestha, Prajowl, additional, Shukla, Urvi, additional, Shum, Omar, additional, Sommerville, Christine, additional, Spelman, Tim, additional, Sullivan, Richard P., additional, Thatavarthi, Umashankar, additional, Tran, Huyen A., additional, Trask, Nanette, additional, Whitehead, Clare L., additional, Mahar, Robert K., additional, Hammond, Naomi E., additional, McFadyen, James D., additional, Snelling, Thomas L., additional, Davis, Joshua S., additional, Denholm, Justin T., additional, and Tong, Steven Y.C., additional

Published
2023
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4. Anticoagulation and Antiplatelet Strategies in Non-Critically Ill Patients with Covid-19

Author

McQuilten, Zoe, primary, Venkatesh, Balasubramanian, additional, Jha, Vivekanand, additional, Roberts, Jason, additional, Morpeth, Susan, additional, Totterdell, James, additional, McPhee, Grace, additional, Abraham, John, additional, Bam, Niraj, additional, Bandara, Methma, additional, Bangi, Ashpak, additional, Barina, Lauren, additional, Basnet, Bhupendra, additional, Bhally, Hasan, additional, Bhusal, Khemr, additional, Bogati, Umesh, additional, Bowen, Asha, additional, Burke, Andrew, additional, Christopher, Devasahayam, additional, Chunilal, Sanjeev, additional, Cochrane, Belinda, additional, Curnow, Jennifer, additional, Dara Reddy, Varaprasad Babu, additional, Das, Santa, additional, Dhungana, Ashesh, additional, Di Tanna, Gian Luca, additional, Dotel, Ravindra, additional, DSouza, Hyjel, additional, Dummer, Jack, additional, Dutta, Sourabh, additional, Foo, Hong, additional, Gilbey, Timothy, additional, Giles, Michelle, additional, Goli, Kasiram, additional, Gordon, Adrienne, additional, Gyanwali, Pradip, additional, Hudson, Bernard, additional, Jani, Manoj, additional, Jevaji, Purnima, additional, Jhawar, Sachin, additional, Jindal, Aikaj, additional, John, M. Joseph, additional, John, Mary, additional, John, Flavita, additional, John, Oommen, additional, Jones, Mark, additional, Joshi, Rajesh, additional, Kamath, Prashanthi, additional, Kang, Gagandeep, additional, Karki, Achyut, additional, Karmalkar, Abhishek, additional, Kaur, Baldeep, additional, Koganti, Kalyan Chakravarthy, additional, Koshy, Jency, additional, Mathew, S K, additional, Lau, Jilllian, additional, Lewin, Sharon, additional, Lim, Lyn-li, additional, Marschner, Ian, additional, Marsh, Julie, additional, Maze, Michael, additional, McGree, James, additional, McMahon, James, additional, Medcalf, Robert, additional, Merriman, Eileen, additional, Misal, Amol, additional, Mora, Jocelyn, additional, Mudaliar, Vijaybabu, additional, Nguyen, Vi, additional, O'Sullivan, Matthew, additional, Pant, Suman, additional, Pant, Pankaj, additional, Paterson, David, additional, Price, David, additional, Rees, Megan, additional, Robinson, James Owen, additional, Rogers, Benjamin, additional, Samuel, Sandhya, additional, Sasadeusz, Joe, additional, Sharma, Deepak, additional, Sharma, Prabhat, additional, Shrestha, Roshan, additional, Shrestha, Sailesh, additional, Shrestha, Prajowl, additional, Shukla, Urvi, additional, Shum, Omar, additional, Sommerville, Christine, additional, Spelman, Tim, additional, Sullivan, Richard, additional, Thatavarthi, Umashankar, additional, Tran, Huyen, additional, Trask, Nanette, additional, Whitehead, Claire, additional, Mahar, Robert, additional, Hammond, Naomi, additional, McFadyen, James David, additional, Snelling, Thomas, additional, Davis, Joshua, additional, Denholm, Justin, additional, and Tong, Steven YC, additional

Published
2022
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6. Lung Cancer in Nepal

Author

Shilpakar, Ramila, primary, Paudel, Bishnu Dutta, additional, Sharma, Rajeev, additional, Silwal, Sudhir Raj, additional, Sapkota, Ranjan, additional, Shrestha, Prajowl, additional, Dulal, Soniya, additional, Piya, Madan Kumar, additional, Tuladhar, Sampurna Man, additional, Neupane, Prakash, additional, Dhimal, Meghnath, additional, Niroula, Abesh, additional, and Uprety, Dipesh, additional

Published
2022
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9. Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status

Author

Mohan, Anant, primary, Shrestha, Prajowl, additional, Madan, Karan, additional, Hadda, Vijay, additional, Upadhyay, Ashish, additional, Mittal, Saurabh, additional, Tiwari, Pawan, additional, Pandey, RM, additional, Garg, Rakesh, additional, Khilnani, GC, additional, and Guleria, Randeep, additional

Published
2020
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15. Therapeutic bronchoscopic interventions for nonmalignant central airway obstruction provide rapid and sustained improvement in symptoms and functional status.

Author

Shrestha, Prajowl, Madan, Karan, Hadda, Vijay, Upadhyay, Ashish, Mittal, Saurabh, Tiwari, Pawan, Pandey, R. M., Garg, Rakesh, Khilnani, G. C., Guleria, Randeep, and Mohan, Anant

Subjects
*BRONCHOSCOPY, *VISUAL analog scale, *TRACHEAL stenosis, *GENERAL anesthesia, *FUNCTIONAL status, *RESPIRATORY obstructions
Abstract

Background: Central airway obstruction (CAO) is a potentially lethal condition that requires urgent endobronchial intervention and may occur due to several nonmalignant causes. The effect of these interventions on clinically relevant outcomes such as symptomatic and functional status over a period of time is, however, sparsely studied. Materials and Methods: Consecutive patients with CAO due to nonmalignant causes and undergoing various therapeutic bronchoscopy procedures were evaluated. Symptoms were assessed using the Visual Analog Scale (VAS) and Speiser score, and functional status was assessed using the 6-min walk test, spirometry, and St. George Respiratory Questionnaire (SGRQ) score at baseline and after 48 h, 4 weeks, and 12 weeks postprocedure. Results: Over 2 years, 31 patients with CAO due to nonmalignant etiology underwent 41 therapeutic bronchoscopic procedures. Majority of procedures (96.8%) were done using the rigid bronchoscope under general anesthesia. Postintubation tracheal stenosis was the most common indication (32.2%). The various procedures included, controlled radial expansion balloon dilatation of the stenotic airway (53.6%), deployment of silicone stents (19.5%), and mechanical debulking of airway tumors (16.1%). Significant improvement occurred in dyspnea and cough scores and in the Speiser score from baseline to 48 h postprocedure, and further improved at 4 weeks and 12 weeks. Similarly, the 6 min walk distance, forced expiratory volume in 1 s, and SGRQ scores progressively improved from baseline to 12 weeks. Complications occurred in 26.8% of total procedures, with no procedure-related mortality. Conclusion: Therapeutic bronchoscopy interventions provide rapid and sustained benefits in symptoms and functional status of participants with CAO of nonmalignant etiology, with an acceptable safety profile. [ABSTRACT FROM AUTHOR]

Published
2020
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23. Guidelines for diagnostic flexible bronchoscopy in adults: Joint Indian Chest Society/National College of chest physicians (I)/Indian association for bronchology recommendations.

Author

Mohan A, Madan K, Hadda V, Tiwari P, Mittal S, Guleria R, Khilnani GC, Luhadia SK, Solanki RN, Gupta KB, Swarnakar R, Gaur SN, Singhal P, Ayub II, Bansal S, Bista PR, Biswal SK, Dhungana A, Doddamani S, Dubey D, Garg A, Hussain T, Iyer H, Kavitha V, Kalai U, Kumar R, Mehta S, Nongpiur VN, Loganathan N, Sryma PB, Pangeni RP, Shrestha P, Singh J, Suri T, Agarwal S, Agarwal R, Aggarwal AN, Agrawal G, Arora SS, Thangakunam B, Behera D, Chaudhry D, Chawla R, Chawla R, Chhajed P, Christopher DJ, Daga MK, Das RK, D'Souza G, Dhar R, Dhooria S, Ghoshal AG, Goel M, Gopal B, Goyal R, Gupta N, Jain NK, Jain N, Jindal A, Jindal SK, Kant S, Katiyar S, Katiyar SK, Koul PA, Kumar J, Kumar R, Lall A, Mehta R, Nath A, Pattabhiraman VR, Patel D, Prasad R, Samaria JK, Sehgal IS, Shah S, Sindhwani G, Singh S, Singh V, Singla R, Suri JC, Talwar D, Jayalakshmi TK, and Rajagopal TP

Abstract

Flexible bronchoscopy (FB) is commonly performed by respiratory physicians for diagnostic as well as therapeutic purposes. However, bronchoscopy practices vary widely across India and worldwide. The three major respiratory organizations of the country supported a national-level expert group that formulated a comprehensive guideline document for FB based on a detailed appraisal of available evidence. These guidelines are an attempt to provide the bronchoscopist with the most scientifically sound as well as practical approach of bronchoscopy. It involved framing appropriate questions, review and critical appraisal of the relevant literature and reaching a recommendation by the expert groups. The guidelines cover major areas in basic bronchoscopy including (but not limited to), indications for procedure, patient preparation, various sampling procedures, bronchoscopy in the ICU setting, equipment care, and training issues. The target audience is respiratory physicians working in India and well as other parts of the world. It is hoped that this document would serve as a complete reference guide for all pulmonary physicians performing or desiring to learn the technique of flexible bronchoscopy., Competing Interests: None

Published
2019
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24. Diffuse Alveolar Haemorrhage as Initial Presentation of Systemic Lupus Erythematosus: A Case Report.

Author

Dhungana A, Shrestha P, Shrestha BD, Baral A, and Sayami G

Subjects
Dyspnea etiology, Female, Humans, Immunosuppressive Agents therapeutic use, Lupus Nephritis therapy, Plasma Exchange, Young Adult, Hemoptysis etiology, Lupus Nephritis complications, Lupus Nephritis diagnosis, Pulmonary Alveoli
Abstract

Diffuse alveolar hemorrhage results from accumulation of red blood cells in the alveolar space originating from alveolar capillaries. Alveolar hemorrhage in Systemic Lupus Erythematosus is rare but catastrophic and can rapidly progress to respiratory failure. We report a 22-year old lady who presented with dyspnoea on exertion, hemoptysis, bilateral leg swelling and oliguria. Diffuse alveolar hemorrhage was confirmed by bronchoalveolar lavage fluid analysis. Serologic tests and renal biopsy confirmed lupus nephritis. She was treated with systemic immunosuppressive therapy and plasma exchange, to which she had a favourable response. Lupus presenting as alveolar hemorrhage is rare which warrants prompt diagnosis and treatment to prevent complications. Keywords: Bronchoalveolar lavage; Case report; Diffuse alveolar hemorrhage; Systemic lupus erythematosus.

Published
2018

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