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Aim : The aim of this study was to analyze the clinical and management aspect of congenital pouch colon. Materials and Methods : This retrospective study was carried out on 40 cases of congenital pouch colon managed in the department of paediatric surgery from 01, January 2000 to 31, December 2005. Results : The incidence of congenital pouch colon (CPC) in the present study was 11.290 % (40 of 354) of all anorectal malformations (ARM) and 19.60% (40 of 204) of high ARM. Of these 40 cases of CPC included in the study, 82.5% were male and 17.5% were female. The average age of presentation to hospital was 3.36 days with a range of 1-11 days; of these 25% patients were admitted with poor general condition. Preoperative diagnosis of CPC was possible in 75% of cases in our study. 60% ( n =24) of cases had incomplete pouch colon (Type III and IV) while 40% ( n =16) had complete pouch colon (Type I and II). Right transverse colostomy was done in 16 patients and colostomy at descending colon just proximal to pouch in two patients for incomplete (Type III and IV) CPC as a primary initial procedure. Ileostomy was done in 14 patients and window colostomy in three patients for complete (Type I and II) CPC. As definitive procedures, pouch excision and abdomino-perineal pull-through of colon was done in 17 patients, coloplasty and abdomino-perineal pull-through of coloplasty colon was done in four patients and pouch excision and abdomino-perineal pull-through of terminal ileum in four patients in our series. None of our patients underwent primary single stage procedure. Conclusion: (1) CPC comprises 11.290 % of all ARM and 19.60% of high ARM. (2) Right transverse colostomy was opted for incomplete pouch colon, while Ileostomy and window colostomy were opted for complete pouch colon as initial surgical procedures. (3) Staged surgical procedures for management of CPC were well tolerated in our series.

Abdominal cerebrospinal fluid (CSF) pseudocyst is an uncommon complication following ventriculo-peritoneal (VP) shunt. The following report′s our experience with three cases of CSF pseudocyst in children. VP shunt was done earlier for communicating hydrocephalus following tubercular meningitis (TBM) in all cases. Clinical presentation was with progressive abdominal distension and features of intestinal obstruction. Clinically we were able to diagnose all cases as CSF pseudocyst peritoneal cavity. Ultrasound examination confirmed the clinical findings in all. CT scan of abdomen and pelvis showed a large unilocular CSF pseudocyst with shunt catheter within it on one patient (case 3). Ultrasound guided aspiration of cyst was done in case 1 alone, but failed to resolve the symptoms. All patients needed formal exploration. Near total cyst excision, adhesiolysis and relocation of peritoneal end of VP shunt catheter in right supra hepatic space was done in all. Two patients who developed shunt tract infection needed shunt removal. The follow up period is 6-8 months.

In order to collect data for this study on PPR, random field samples were taken. A total of 40 samples from Azamgarh district were randomly taken from goats during the study period (September 2021 to August 2022) who were exhibiting PPR clinical signs like anorexia, depression, fever (106 ±1°F), occulo nasal discharges, diarrhoea with soiled hind quarter, shrunken eyes, coughing, and respiratory distress. Out of those, 25 animals died during the course of the study. Samples from the dead animals were taken, and the results showed that the animals had stomatitis, consolidated or congested pneumonic lungs, generalised lymphadenopathy with necrosis and congestion of some lymph nodes,atrophied spleens, and hemorrhagic gastroenteritis. The seroprevalence noticed using c-ELISA was 92.5%. PCR analysis was done on tissue samples. Six of those samples tested positive for the PPR virus, prevalence by PCR was 24%. In some cases, a histopathological analysis indicated lung congestion and edema, but in PCR-positive cases, a network of fibrin was infiltrated with neutrophils, forming syncytia and gaint cells along with intracytoplasmic inclusion bodies. The alveoli, bronchioles, alveolar wall, and interstitium of the lungs all had neutrophil and mononuclear cell infiltration. Necrosis and lymphoid cell loss were visible in the lymphoid organs. Using immunohistochemical labelling, the PPR virus antigen accumulation was found in the lung alveolar epithelial cells and macrophages. [ABSTRACT FROM AUTHOR]

BackgroundAI in healthcare services is advancing every day, with a focus on uprising cognitive capabilities. Higher cognitive functions in AI entail performing intricate processes like decision-making, problem-solving, perception, and reasoning. This advanced cognition surpasses basic data handling, encompassing skills to grasp ideas, understand and apply information contextually, and derive novel insights from previous experiences and acquired knowledge. ChatGPT, a natural language processing model, exemplifies this evolution by engaging in conversations with humans, furnishing responses to inquiries. ObjectiveWe aimed to understand the capability of ChatGPT in solving doubts pertaining to symptoms and histological features related to subject of oral pathology. The study’s objective is to evaluate ChatGPT’s effectiveness in answering questions pertaining to diagnoses. MethodsThis cross-sectional study was done using an AI-based ChatGPT application that provides free service for research and learning purposes. The current version of ChatGPT3.5 was used to obtain responses for a total of 25 queries. These randomly asked questions were based on basic queries from patient aspect and early oral histopathologists. These responses were obtained and stored for further processing. The responses were evaluated by five experienced pathologists on a four point liekart scale. The score were further subjected for deducing kappa values for reliability. Result & Statistical AnalysisA total of 25 queries were solved by the program in the shortest possible time for an answer. The sensitivity and specificity of the methods and the responses were represented using frequency and percentages. Both the responses were analysed and were statistically significant based on the measurement of kappa values. ConclusionThe proficiency of ChatGPT in handling intricate reasoning queries within pathology demonstrated a noteworthy level of relational accuracy. Consequently, its text output created coherent links between elements, producing meaningful responses. This suggests that scholars or students can rely on this program to address reasoning-based inquiries. Nevertheless, considering the continual advancements in the program’s development, further research is essential to determine its accuracy levels in future versions.