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Objective: To compare the effect of a non-pneumatic anti-shock garment (NASG) on blood loss from obstetric haemorrhage with standard management of obstetric haemorrhage. Methods: This is an observational study of consecutive obstetric haemorrhage cases before and after the introduction of the non-pneumatic anti-shock garment conducted in a tertiary care centre in Southern India. A total of 122 women were included in the study out of which, 48 women were in the pre-intervention group and 74 in the post-intervention group. Blood loss was measured and recorded before and after the introduction of NASG. Results: The number of patients with significant blood loss (>750 ml) decreased from 81.3% to 50% after the use of NASG. The number of women with shock index >0.7 also reduced significantly from 81.3% to 56.8% thus reflecting the lower number of women requiring blood transfusion in the post-intervention group (56.2% v/s 14.9%). There was also a decrease in the number of cases requiring surgical management in the post NASG intervention group with a significant p-value of

Globally, colorectal cancer (CRC) is a leading cause of cancer-related mortality. Dietary habits, inflammation, hereditary characteristics, and gut microbiota are some of its causes. The gut microbiota, a diverse population of bacteria living in the digestive system, has an impact on a variety of parameters, including inflammation, DNA damage, and immune response. The gut microbiome has a significant role in colon cancer susceptibility. Many studies have highlighted dysbiosis, an imbalance in the gut microbiota's makeup, as a major factor in colon cancer susceptibility. Dysbiosis has the potential to produce toxic metabolites and pro-inflammatory substances, which can hasten the growth of tumours. The ability of the gut microbiota to affect the host's immune system can also influence whether cancer develops or not. By better comprehending these complex interactions between colon cancer predisposition and gut flora, new preventive and therapeutic techniques might be developed. Targeting the gut microbiome with dietary modifications, probiotics, or faecal microbiota transplantation may offer cutting-edge approaches to reducing the risk of colon cancer and improving patient outcomes. The complex connection between the makeup of the gut microbiota and the emergence of colorectal cancer is explored in this narrative review., (© Association of Microbiologists of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)