1. Cerebrovascular events and thrombolysis in pulmonary embolism-induced cardiac arrest: a case series and key challenges
- Author
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Youping Zhang, Shu Peng, Karl Nelson S.Marquez, Xiangning Fu, Bo Ai, Hua Yan, Wei Zhu, and Shusheng Li
- Subjects
Cerebrovascular events ,Cardiac arrest ,Cardiac pulmonary resuscitation ,Pulmonary embolism ,Thrombolysis ,Case series ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background and purpose Cerebrovascular events during thrombolysis in cardiac arrest (CA) caused by pulmonary embolism (PE) is a life-threatening condition. However, the balance between cerebrovascular events and thrombolytic therapy in PE-induced CA remains a great challenge. Methods In this study, we reported three unique cases regarding main concerns surrounding cerebrovascular events in thrombolytic therapy in PE-induced CA. Results The patient in the case 1 treated with thrombolysis during CPR and finally discharged neurologically intact. The patient in the case 2 received delayed thrombolysis and died eventually. The patient in the case 3 was contraindicated to thrombolysis due to the complication of subarachioid hemorrahage and died within days. Conclusions Our case series highlights three proposed approaches to consider before administering thrombolysis as a treatment option in PE-induced CA patients: (1) prolonging the resuscitation, (2) administering thrombolysis promptly, and (3) ruling out cerebrovascular events.
- Published
- 2024
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