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Background: Transcatheter arterial chemoembolization (TACE) is an effective treatment for hepatocellular carcinoma (HCC), however, the complications of TACE have gradually become a concern of clinicians. Injury to the bile duct has been the focus of many scholars. Case Presentation: HCC was diagnosed in a 51-year-old female patient, and the first TACE was performed on April 10, 2020. The second TACE was performed on October 18, 2021. After the second TACE, The patient suffered from nausea, jaundice, and body itching. Computed tomography (CT) of the abdomen showed that the lower common bile duct was obviously blocked by the solidified lipiodol accompanied by dilatation of intrahepatic and extrahepatic bile ducts on October 27, 2021. Endoscopic retrograde cholangiopancretography (ERCP) and endoscopic nasobiliary drainage (ENBD) were performed on October 29, 2021. The deposition of lipiodol in the common bile duct was significantly reduced. Conclusion: After the transcatheter arterial chemoembolization for hepatocellular carcinoma, we should be on alert for damage to the bile duct, and pay attention to the deposition of lipiodol in the common bile duct.

Due to the simplicity of vacancy creation, Eu2+-doped melilite is an outstanding persistent luminescence (PersL) material with a continuing glow lifetime of more than several hours. In this paper, we...

Venous thromboembolism (VTE) is a common complication of colon cancer. In the present study, we aimed to explore the association of the oncogene COX7C to VTE in colon cancer patients. Samples from 580 patients were examined histologically for VTE and pathological characteristic of cancer. Gene mutation and expression analysis were performed using polymerase chain reaction-based assays to evaluate genes related to VTE, including COX7C. Univariate analysis between clinical pathological factors and VTE was conducted. Logistic regression analysis was performed for the prediction of VTE by pathological factors and gene expressions. Among patients investigated, a total of 56 patients had VTE. COX7C had a significant correlation with VTE (p 0.001). Despite a correlation between tumor size, invasion depth of tumor, lymph node metastasis, lymph node metastasis, distant metastasis, lymphovascular invasion, histologic type and pathology type, Ki-67, and some other genes, to VTE (p 0.05), only COX7C expression demonstrated significance in its ability to predict VTE. Here, we show that COX7C upregulation strongly correlates with VTE in colon cancer, which implicates its role as a biomarker and therapeutic target of VTE in colon cancer.

The surface electromyography (sEMG) signal is the sum of the action potentials generated by the active motor units and detected over the skin, which has great performance on the recognition of human movements and the diagnosis of injuries because of its strong muscle specificity and differences in exercise patterns. This paper employs the Cerebellar model neural network (CMNN) as a classifier of the ankle motion based on sEMG. We testify our method on the data recorded from six healthy subjects who are on isokinetic ankle eversion and inversion. The results show that the classification accuracy is higher than 96.9% with less training times. For the future application, the CMNNs can be employed to predict the ankle motions in real-time to control exoskeleton robot.

Zearalenone (ZEN), one of the most dangerous mycotoxins, causes enormous economic losses in the food and feed industries. To solve the problem of ZEN pollution, ZEN detoxifying enzymes are in emergent need. In this study, a zearalenone lactonohydrolase from Trichoderma aggressivum, denoted as ZHD-P, was heterologously expressed and characterized. The intracellular ZHD-P from E. coli BL21(DE3) exhibited high activity for ZEN degradation (191.94 U/mg), with the optimal temperature and pH of 45 °C and 7.5–9.0, respectively. With excellent temperature stability, the intracellular ZHD-P retained 100% activity when it was incubated at 25–40 °C for 1 h. Furthermore, we firstly constructed an E. coli cell surface display system for ZHD-P. The surface-displayed ZHD-P exhibited high activity against ZEN and showed optimal activity at 40 °C and pH 9.0. With superior pH stability, the surface-displayed ZHD-P retained 80% activity when it was incubated at pH 5.0–11.0 for 12 h. Interestingly, the metal ions tolerance of the surface-displayed ZHD-P was better than the intracellular form. Additionally, the surface-displayed ZHD-P could be reused four times with the residual enzyme activity of more than 50%. The biotoxicity assessment using P. phosphoreum T3 indicated that ZEN could be degraded into hypotoxic products by the intracellular or surface-displayed ZHD-P. ZHD-P could be feasible for ZEN detoxification.

As to determine the effect of post-remission therapy in prolonging survival and duration of remission after complete remission, 50 patients with APL in complete remission induced by retinoic acid (RA) were divided into three groups randomly: (A) 30 cases, treated by alternate chemotherapy with RA; (B) 10 cases, with RA alone; (C) 10 cases, only with chemotherapy. The survival curves showed that Group A had the survival time more than 1 year in 87.4%, more than 2 year in 80.7%. 26/30 cases were survival and still in remission, the survival curve tend to be a plateau at 16 months. In Group B more than 1 year in 45.7%. In Group C, more than 1 year in 50%. (Keplan-Meier χ2=8.93P

This paper presents novel algorithms for optimal bit allocation and uniform rate control in video coding. By introducing an important factor of the frame picture in the Group of Pictures (GOP), the bit allocation is formulated as a convex programming problem, and is efficiently solved by designed algorithm which combines Lagrangian method and Boundary Linear Search method (L-BLS). Then, an efficient rate control scheme is proposed and is also simulated and verified in the MPEG2 video coding. Experimental results show that the proposed scheme can achieve a better picture quality, namely, PSTN reached average 1.1db improvement than the Test Model5 (TM5) under the same target bits rate and mismatch error.

An adaptive LZW algorithm for compressing partial bitstreams of Virtex FPGAs was presented. The adaptations of algorithm were based on analysis of the three-level data regularity of the configuration bitstreams. Partial bitstreams were created through Xilinx module-based partial reconfiguration flow. The experiment demonstrated down to 43.69% compression ratio for partial bitstreams of several real-world applications.