460 results on '"Shuto, Tsuyoshi"'
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2. Trimerization profile of type IV collagen COL4A5 exon deletion in X-linked Alport syndrome
3. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors
4. Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases
5. Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH
6. T3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model
7. Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor
8. Metformin ameliorates the severity of experimental Alport syndrome
9. TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs
10. The effect of Porphyromonas gingivalis on inflammatory pathology in normal or COPD airway
11. Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases
12. T 3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model.
13. A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome
14. Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model
15. CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion
16. The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties
17. Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions
18. Hydrogen bonds connecting the N-terminal region and the DE loop stabilize the monomeric structure of transthyretin.
19. Free radical scavenging, α-glucosidase inhibitory and lipase inhibitory activities of eighteen Sudanese medicinal plants
20. Negative Cross-Talk between TLR2/4-Independent AMPKα1 and TLR2/4-Dependent JNK Regulates S. pneumoniae–Induced Mucosal Innate Immune Response
21. Long-term treatment with EGFR inhibitor erlotinib attenuates renal inflammatory cytokines but not nephropathy in Alport syndrome mouse model
22. A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells
23. Evaluation of Three-Dimensional Cultured HepG2 Cells in a Nano Culture Plate System: an In Vitro Human Model of Acetaminophen Hepatotoxicity
24. Novel Keap1-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome Mouse Model
25. Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events
26. Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events
27. Characterization of Hepatic Cellular Uptake of α1-Acid Glycoprotein (AGP), Part 2: Involvement of Hemoglobin β-Chain on Plasma Membranes in the Uptake of Human AGP by Liver Parenchymal Cells
28. Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells
29. Elucidation of interaction factors between COPD and lung cancer
30. Mild electrical stimulation and heat shock can suppress acute kidney injury (AKI) to chronic kidney disease (CKD) transition
31. Identification of W09D10.4/PPTC7 as a novel AMPK-associated healthspan modulatory factor by using C. elegans Healthspan Auto-monitoring System (C-HAS)
32. The effect of intratracheal administration of thyroid hormone (T3) in chronic obstructive pulmonary disease (COPD) mouse model simulating disease type classification.
33. Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for glomerulosclerosis in mouse model of chronic kidney disease
34. Utilizing split-luciferase-based HTS platform and natural product extracts library yielded cyclosporin A as candidate drug for Alport syndrome
35. CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation
36. Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway
37. Differential mode of cholesterol inclusion with 2‐hydroxypropyl‐cyclodextrins increases safety margin in treatment of Niemann‐Pick disease type C
38. Mild Electrical Stimulation Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degradation
39. Non-thermal and transient thermal effects of burst 100 MHz sinusoidal electric fields on apoptotic activity in HeLa cells
40. The role of discoidin domain receptor 2 in the renal dysfunction of alport syndrome mouse model
41. Lipopolysaccharide decreases SIGIRR/TIR8 gene expression by suppressing Sp1 via TLR4-p38 mapkinase pathway in monocytes and neutrophils: 259
42. Increased IL-17C production by the TLR3 ligand poly (I:C) in primary cystic fibrosis airway epithelial cells: 241
43. Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans
44. Combined effects of cisplatin and photon or proton irradiation in cultured cells: radiosensitization, patterns of cell death and cell cycle distribution
45. MEF/ELF4 transactivation by E2F1 is inhibited by p53
46. A novel condition of mild electrical stimulation exerts immunosuppression via hydrogen peroxide production that controls multiple signaling pathway
47. Higher Blood Uric Acid in Female Humans and Mice as a Protective Factor against Pathophysiological Decline of Lung Function
48. Trimerization and Genotype–Phenotype Correlation of COL4A5 Mutants in Alport Syndrome
49. Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation in Vitro and Modulates Downstream Pathogenesis in Vivo
50. Intratracheal GLP-1 receptor agonist treatment up-regulates mucin via p38 and exacerbates emphysematous phenotype in mucus hypersecretory obstructive lung diseases
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