27 results on '"Siamak Bashar"'
Search Results
2. Investigating the Effects of Intrinsic Foot Muscle Exercises on Dynamic Balance after Sub-Acute Ankle Sprain
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Sepideh Sekkehchi, Siamak Bashardoust Tajali, Zinat Ashnagar, and Fatemeh Majdi
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Ankle sprain ,Intrinsic muscles ,Foot exercises ,Medicine - Abstract
Introduction: This study compares the efficacy of routine treatment plus short foot exercises (SFE) with routine treatment alone on dynamic balance and pain in subjects with sub-acute ankle sprain. Materials and Methods: A total of 32 patients (18-45 years old) with primary ankle sprain were randomly enrolled into the control group performing routine treatment alone or the SFE group performing routine treatment plus SFE. The dynamic balance was assessed using the star excursion balance test. Pain and ankle dorsiflexion range of motion were assessed using the numeric pain rating scale and a goniometer. The outcomes were evaluated at the baseline and after the end of treatment. The groups were compared using the one-way analysis of variance/analysis of covariance test. The effect sizes also were calculated to determine the efficacy of the SFE. Results: Dynamic balance in the SFE group had a significant increase in the anterior, lateral, medial, and anteromedial directions compared to the control group (P=0.001, P=0.002, P=0.014, P=0.0001). No significant differences were observed between the groups in other directions of the star excursion balance test (P>0.05). Additionally, pain intensity was lower significantly in the SFE group than in the control group (P=0.0001). In the SFE group ankle dorsiflexion range was significantly more than the control group (P=0.025). The effect sizes also showed a high efficacy favoring SFE. Conclusion: The combination of routine treatment and SFE can be an effective intervention for managing ankle sprain.
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- 2024
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3. WHAT IS THE DEVELOPMENTAL POTENTIAL OF MATURE OOCYTES DERIVED FROM RESCUE IN-VITRO MATURATION (RIVM)?
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Iryna Kuznyetsova, Siamak Bashar, Adi Kuperman Shani, Lilach Marom Haham, and Clifford Librach
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Reproductive Medicine ,Obstetrics and Gynecology ,Biology ,In vitro maturation ,Cell biology - Published
- 2021
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4. Investigating the Immediate Effects of Static and Dynamic Stretching Exercises of Lower Extremities Muscles on Core Stability in Young Healthy Females
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Elaheh Mehdizadeh Harikandei, Siamak Bashardoust Tajali, Zinat Ashnagar, and Fatemeh Manafi Havigh
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Stretching exercises ,Dynamic exercise ,Warm-up exercise ,Muscle strength ,Physical endurance ,Medicine - Abstract
Introduction: This study investigates the immediate effects of warm-up exercises, specifically static and dynamic stretches for the lower extremities, on strength, endurance, flexibility, motor control, and core stability function in young, healthy females. Materials and Methods: A total of 60 healthy, active women aged 19-30 years were randomly divided into three groups as follows: Static stretching (SS), dynamic stretching (DS), and a control group (CG), which received no exercises. Evaluation methods for core stability included strength, endurance, sit-and-reach, Y-balance, and bilateral squat tests. Meanwhile, these tests were conducted before and after the prescribed exercise protocols. Results: Both the SS and DS groups experienced significant increases in all core stability components compared to their baseline values (P0.05). In addition, dynamic exercises demonstrated a higher effectiveness than static exercises for most parameters (P
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- 2024
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5. Low-Energy Versus Middle-Energy Extracorporeal Shockwave Therapy for Treating Pes Anserine Bursitis
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Raghad Talib Taha Khazraji, Siamak Bashardoust Tajali, Kazem Malmir, and Ali Hussien Al-Hafidh
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Shockwave ,Pes anserine ,Bursitis ,Pain ,Function ,Medicine - Abstract
Introduction: Pes anserine bursitis (PAB) is a painful status inside the knee that may interfere with functional activities. Extracorporeal shockwave therapy (ESWƬ) may treat this disorder. Objective: Comparing the effects of low- versus middle-energy ESWƬ on pain and functional activity in patients with sub-acute PAB. Materials and Methods The study was a single-blind randomized trial. Twenty-eight patients with sub-acute PAB were randomly divided into two groups and received either low or middle-energy ESWƬ for three weeks. The numeric pain rating scale (NPRS), short-form McGill pain questionnaire (SF-MPQ), timed up and go (TUG) test, and Western Ontario and McMaster universities index (WOMAC) were evaluated before and 2 and 3 weeks after the intervention. Results: A significant improvement was observed for low-energy ESWT in terms of NPRS (P=0.001), SF-MPQ (P
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- 2024
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6. Is the zona pellucida thickness of human embryos influenced by women's age and hormonal levels?
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Siamak Bashar, Rodica Mandel, Clifford Librach, Gelareh Motamedi, Agata Sojecki, and Hanna Balakier
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Adult ,Male ,Infertility ,Fertilization in Vitro ,Biology ,Andrology ,Young Adult ,Basal (phylogenetics) ,Pregnancy ,medicine ,Humans ,Sperm Injections, Intracytoplasmic ,Prospective cohort study ,Zona pellucida ,Zona Pellucida ,Cell Size ,Osmolar Concentration ,Obstetrics and Gynecology ,Embryo ,Embryo Transfer ,Embryo, Mammalian ,Prognosis ,medicine.disease ,Hormones ,Embryo transfer ,medicine.anatomical_structure ,Reproductive Medicine ,embryonic structures ,Female ,Embryo quality ,Maternal Age - Abstract
Objective To evaluate whether zona pellucida thickness (ZPT) of human embryos is correlated with maternal age, patient's hormonal status, embryo quality, and IVF outcomes. Design Prospective study. Setting University-affiliated IVF clinic. Patient(s) Couples undergoing IVF-ET cycles. Intervention(s) Zona measurements, clinical data collection. Main Outcome Measure(s) Correlation between the ZPT and maternal age, basal FSH and E 2 levels, stimulation protocols, cause of infertility, embryo quality, and implantation/pregnancy rates. Result(s) The measurements of ZPT were collected from 5,184 day 3 human embryos originated from 744 IVF patients. The overall mean ZPT was 16.18 ± 2.00 μm. No significant correlation was observed between the ZPT and the patient's age, E 2 values on the day of hCG administration, basal concentration of serum FSH, stimulation protocol, infertility diagnosis, and implantation/pregnancy rates. The ZPT was strongly influenced only by the embryo quality: Embryos with good morphology exhibited considerably thinner ZP compared with those of less favorable morphology (mean 15.87 ± 2.48 μm vs. 16.36 ± 2.57 μm, respectively). The ZPT had no significant impact on the implantation and pregnancy rates. Conclusion(s) The thickness of the human ZP of day 3 embryos is not influenced by women's age and hormonal levels. The strong correlation between ZPT and embryo quality suggests that thickness of ZP depends on inherent embryo properties. The overall ZPT is not a good predictive indicator for IVF clinical outcomes.
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- 2012
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7. Periovulatory Increases in Tissue Homing Potential of Circulating CD56brightCells Are Associated with Fertile Menstrual Cycles
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B. Anne Croy, Julie Horrocks, Siamak Bashar, Sharon S. Evans, Francis R. Tekpetey, Suzanne D. Burke, Marianne J. van den Heuvel, and Kota Hatta
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Adult ,Ovulation ,medicine.medical_specialty ,Stromal cell ,Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,Lymphocyte ,Clinical Biochemistry ,Uterus ,Biology ,Biochemistry ,Article ,Endocrinology ,Antigens, CD ,Pregnancy ,Internal medicine ,medicine ,Humans ,Lymphocyte Count ,Lymphocytes ,Menstrual Cycle ,Menstrual cycle ,media_common ,Biochemistry (medical) ,Decidua ,Pregnancy Outcome ,Decidualization ,Embryo Transfer ,CD56 Antigen ,Embryo transfer ,Killer Cells, Natural ,medicine.anatomical_structure ,Female ,Infertility, Female - Abstract
CD56(bright) lymphocytes appear in the uterus 3-5 d after ovulation coincident with the onset of stromal cell decidualization. Although the source of these uterine immune cells is not defined, a subset of blood CD56(bright) cells exhibits enhanced capacity to adhere to decidual vascular endothelium during the periovulatory period of menstrual cycles. In this study, the effects of early pregnancy on the adhesive capacity of CD56(bright) cells to bind uterine substrates were examined in a time-course study of 18 infertile women undergoing natural cycles before transfer of frozen/thawed embryos and 18 infertile women undergoing controlled ovarian stimulation. There were three pregnancies in the natural cycle group and seven in the hormone-stimulated cohort. Hormone levels, and number and quality of transferred embryos were similar between pregnant and nonpregnant cycles. However, the adhesive function of CD56(bright) cells increased before ovulation in hormone-treated women who became pregnant and before embryo transfer in naturally cycling women who became pregnant. This pattern of incremental adhesion, which was less frequently observed in unsuccessful cycles, suggests a role for NK cells in implantation. These results support the idea that temporal control of NK cell homing to the uterine microenvironment is a prerequisite to pregnancy.
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- 2005
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8. Effects of Blood Flow Restriction on Pain and Muscle Thickness Following Tendinopathy: A Case Study
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Zahra Poursaleh Begi, Siamak Bashardoust Tajali, Seyed Mohsen Mir, Saeed Talebian, Azadeh Shadmehr, and Zinat Ashnagar
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Blood flow restriction ,Proximal effect ,Supraspinatus tendinopathy ,Medicine - Abstract
Introduction: Blood flow restriction (BFR) training, in which an inflatable cuff partially occludes blood flow around the proximal portion of a limb, coupled with low-load resistance exercise (LLRE) has resulted in gains comparable with traditional progressive resistive exercise in healthy populations. The use of BFR with LLRE may help people with supraspinatus tendinopathy through proximal effects to improve strength and muscle size. The purpose of this case report is to describe the proximal effect of the LLRE+BFR program on a patient with supraspinatus tendinopathy. Materials and Methods: The patient was a 40-year-old man with a history of shoulder pain and weakness for the past months. He received an LLRE+BFR program for his right shoulder including rotator cuff and scapular strengthening exercises and lower limbs aerobic exercises based on protocols of strengthening and aerobic exercises of BFR. Outcomes measured at baseline and 4 weeks included the 4 items: 1) Strength of supraspinatus muscle and four scapular stabilizer muscles including serratus anterior strength, middle trapezius strength, and lower trapezius strength by dynamometer, 2) supraspinatus thickness by ultrasound, 3) pain pressure threshold of supraspinatus and deltoid muscles by algometer, and 4) pain reported bay in each session based on pain numeric scale. Results: After 6 weeks, the strength of supraspinatus and scapular stabilizers except for the lower trapezius increased. The supraspinatus thickness and pain pressure threshold in the supraspinatus and deltoid muscle also increased after 4 weeks. The mean of pain reported by the patient based on the pain numeric scale before and after each session was also decreased. Conclusion: The patient had measurable improvements following the use of an LLRE+BFR program. LLRE+BFR program may be an option for strength training in people with supraspinatus tendinopathy; however, more research is needed to determine effectiveness across the population of people with supraspinatus tendinopathy.
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- 2023
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9. Sperm content of postacrosomal WW binding protein is related to fertilization outcomes in patients undergoing assisted reproductive technology
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Siamak Bashar, Peter Sutovsky, Clifford Librach, Mahmoud Aarabi, Richard Oko, Sergey I. Moskovtsev, and Hanna Balakier
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Infertility ,Adult ,Male ,medicine.medical_treatment ,Embryonic Development ,Biology ,Intracytoplasmic sperm injection ,Male infertility ,Andrology ,Human fertilization ,Perinuclear theca ,medicine ,Humans ,Prospective Studies ,Sperm Injections, Intracytoplasmic ,reproductive and urinary physiology ,Assisted reproductive technology ,Sperm Count ,urogenital system ,Seminal Plasma Proteins ,Obstetrics and Gynecology ,Oocyte activation ,medicine.disease ,Flow Cytometry ,Sperm ,Immunohistochemistry ,Spermatozoa ,3. Good health ,Blastocyst ,Treatment Outcome ,Reproductive Medicine ,Sperm Motility ,Female ,Carrier Proteins ,Biomarkers - Abstract
Objective To determine the levels of postacrosomal WW binding protein (PAWP) in the spermatozoa of men that were used clinically for intracytoplasmic sperm injection (ICSI) and to correlate them with infertility treatment outcomes. Design Prospective clinical and laboratory study. Setting University-based laboratory and infertility clinic. Patient(s) Men undergoing ICSI for the treatment of couples' infertility (n = 110). Intervention(s) Quantitative analysis of sperm PAWP levels by flow cytometry and developmental analysis of PAWP expression by immunoblotting, immunofluorescence, and immunohistochemistry. Main Outcome Measure(s) PAWP flow-cytometric levels and immunolocalization in spermatozoa. Result(s) A strong positive correlation was found between PAWP expression levels and fertilization rates after ICSI, with high levels of PAWP being associated with higher fertilization rates; the positive correlation was independent of age, DNA fragmentation index, and other sperm parameters. PAWP expression levels were correlated with embryonic development, with high levels of PAWP being associated with a lower number of arrested embryos within 3–5 days post-ICSI. PAWP expression was detected during the late stages of human spermiogenesis in elongating spermatids, confirming previous findings in various animal models. Conclusion(s) Our clinical data from infertile couples demonstrate significant correlations between sperm PAWP levels and both fertilization rates and normal embryonic development after ICSI. Considering its proposed role in the initiation of oocyte activation, we suggest that PAWP could have potential applications in the diagnosis and treatment of infertility.
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- 2014
10. Effects of Intramuscular Electrical Stimulation on Pain and Dysfunction Following Upper Trapezius Trigger Points
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Monavar Hadizadeh, Siamak Bashardoust Tajali, Behrouz Attarbashi Moghadam, Shohreh Jalaei, and Mahnaz Bazzaz
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Electrical stimulation ,Dry needling ,Myofascial pain syndrome ,Upper trapezius ,Trigger point ,Medicine - Abstract
Introduction: The purpose of the present study was to investigate the effects of single-session intramuscular electrical stimulation (IMES) on pain and dysfunction following active trigger points in the upper trapezius muscle. Materials and Methods: Volunteers (30 females) with active trigger points in the upper trapezius muscle were randomly divided into two IMES and placebo groups. For the IMES group, a needle was inserted into the trigger point, and electrical stimulation was applied to generate a pain-free contraction. For the placebo group, the intervention procedure was exactly the same, but there was no electrical stimulation. Pain by visual analog scale (VAS), pain pressure threshold (PPT), range of motion (ROM), and disability by neck disability index (NDI) were assessed as main outcome measures before, immediately after, and one week after conducting intervention by another blinded researcher. Results: The VAS scales were improved in both groups but were significantly lower in the IMES group one week after treatment. The PPT and ROM scores were substantially higher in the IMES group one week after the treatment. The NDI indexes significantly reduced for both groups, with no significant differences between them. Conclusion: IMES effectively improves pain, PPT, ROM, and NDI, following trigger points in the upper trapezius muscle. Further studies are required to investigate the IMES’s long-term effects.
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- 2023
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11. Effects of Combining Diaphragmatic Exercise with Physiotherapy on Chronic Neck Pain: A Randomized Clinical Trial
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Sima Mosallaiezadeh, Siamak Bashardoust Tajali, Azadeh Shadmehr, and Behrouz Attarbashi Moghadam
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Diaphragmatic exercise ,Strength exercise ,Pain ,Chronic neck pain (CNP) ,Medicine - Abstract
Introduction: Chronic neck pain (CNP) is of the most common symptoms of musculoskeletal disorder. Diaphragmatic exercises can reduce pain, and disability, improve proprioception, and correct forward head posture (FHP) in patients with CNP. The present study aims to determine the effect of combining diaphragmatic exercises with physiotherapy on pain, disability, and active range of motions of cervical and FHP in individuals with CNP. Materials and Methods: Thirty women with CNP were randomly divided into two combined groups of diaphragmatic exercises and physiotherapy (DEPT) and PHYSIOTHERAPY ALONE (PT). Each person received ten sessions of treatment over two weeks. The results were assessed in the first and tenth sessions as well as two weeks later. Pain intensity was measured by visual analogue scale (VAS), disability by neck disability index (NDI), cervical active range of motions (CAROMs) by goniometry, and FHP by a lateral photograph. Results: The VAS, neck disability index (NDI), CAROMs, and FHP were improved after the tenth session and in a two-week follow-up (P
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- 2023
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12. A sperm-derived WW domain-binding protein initiates zygotic development in human and mouse and determines male-factor infertility
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Sergey I. Moskovtsev, Richard Oko, Hanna Balakier, Siamak Bashar, Clifford Librach, Peter Sutovsky, and Mahmoud Aarabi
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WW domain ,Genetics ,Zygote ,Reproductive Medicine ,biology ,Binding protein ,biology.protein ,Obstetrics and Gynecology ,Male factor infertility ,Sperm - Published
- 2014
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13. Immediate Effects of Electro Acupuncture versus Laser Acupuncture on Pain and Disability in Women with Chronic Cervical Myofascial Pain Syndrome
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Atefeh Bahadori Bozchelooee, Siamak Bashardoust Tajali, Zahra Fakhari, and Monavar Hadizadeh
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Electro acupuncture ,Laser acupuncture ,Neck pain ,Myofascial pain syndrome ,Medicine - Abstract
Introduction: Neck pain is the fourth leading cause of disability worldwide. This study aims to investigate the effects of Electro Acupuncture (EA) versus Laser Acupuncture (LA) on symptoms of women with chronic cervical myofascial pain syndrome. Materials and Methods: This is a single-blind randomized controlled clinical trial. Thirty women with chronic cervical myofascial pain syndrome were randomly divided into three groups: EA, LA, and sham. The EA group received electrical stimulation through needles at standard acupuncture points, while the LA group received low-intensity laser irradiation at the same points. The passive laser probe was applied for the sham group. The outcome measures were neck pain pressure threshold, neck pain severity, neck disability, and cervical range of motion Results: The pain severity and disability were significantly lower in the EA group than in the other two groups. The neck range of motion (cervical lateral flexion and rotation) and pain pressure threshold increased significantly in the EA group immediately and one week after the intervention. Conclusion: Both EA and LA interventions may be effective in alleviating the symptoms of cervical myofascial pain syndrome, but the EA can be more effective in reducing neck pain and disability in women with cervical myofascial pain syndrome.
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- 2022
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14. Trafficking of Peripheral Blood CD56Bright Cells to the Decidualizing Uterus -New Tricks for Old Dogmas?
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Julie Horrocks, Marianne J. van den Heuvel, Siamak Bashar, Suzanne Taylor, B. Anne Croy, and Crystal G. Peralta
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Ovulation ,medicine.medical_specialty ,Stromal cell ,media_common.quotation_subject ,Lymphocyte ,Immunology ,Biology ,Article ,Natural killer cell ,Mice ,Cell Movement ,Pregnancy ,Internal medicine ,medicine ,Decidua ,Immunology and Allergy ,Animals ,Humans ,Decidual cells ,Lymphocytes ,media_common ,Obstetrics and Gynecology ,Decidualization ,Dendritic cell ,CD56 Antigen ,medicine.anatomical_structure ,Endocrinology ,Reproductive Medicine ,Female - Abstract
CD56(bright) lymphocytes become abundant in the human uterus during every menstrual cycle, following the surge in pituitary-derived luteinizing hormone (LH), which initiates final oocyte maturation. While the uterus is host to some CD56(bright) cells prior to ovulation, the rapid increase is thought to be due to proliferation of the resident population, accompanied by recruitment of CD56(bright) lymphocytes from the circulation. The rapid increase in CD56(bright) cells is concurrent with the onset of decidualization, the transformation of uterine stromal cells into secretory decidual cells. Uterine CD56(bright) cells proliferate and differentiate to become the predominant lymphocytes of the post-ovulatory uterus. These distinct, tissue-specific natural killer (NK) cells either die prior to menses or increase in number during early pregnancy, and then decline toward the end of the first trimester. Since lymphocytes home to tissues from the circulation, we investigated mechanisms of NK cell traffic over the course of natural menstrual cycles by measuring functional interactions between CD56+ cells from blood and endothelial cells using the Stamper-Woodruff assay of lymphocyte adhesion to frozen tissue sections. While a baseline level of adhesion was maintained throughout the cycle, elevated l-selectin-dependent adhesion of peripheral blood CD56(bright) cells occurred during a peri-ovulatory window. However, there were no significant menstrual cycle-induced changes in the transcription of l-selectin, alpha 4 integrin or LFA-1, or in expression of these proteins by NK cells, suggesting that the enhanced adhesion was due to post-translational modifications of these molecules. Quantitative RT-PCR failed to amplify the message for LH receptor or the alpha or beta forms of progesterone or estrogen receptors from blood NK cell subsets. Thus, we conclude that the actions of LH, E(2,) and P(4) on NK cells that promote interactions with endothelium and potential uterine homing are indirectly mediated through the responsiveness of other cell types.
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- 2005
15. Menstrual cycle hormones induce changes in functional interactions between lymphocytes and decidual vascular endothelial cells
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Siamak Bashar, Kota Hatta, Jennifer E. Lewis, Julie Horrocks, B. Anne Croy, Suzanne Taylor, Suzanne D. Burke, and Marianne J. van den Heuvel
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Adult ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Lymphocyte ,media_common.quotation_subject ,Clinical Biochemistry ,Uterus ,Cell Communication ,Biochemistry ,Article ,Mice ,Endocrinology ,Internal medicine ,medicine ,Cell Adhesion ,Animals ,Humans ,Lymphocytes ,Cell adhesion ,Ovulation ,Menstrual Cycle ,Progesterone ,media_common ,biology ,Cluster of differentiation ,Estradiol ,Biochemistry (medical) ,Decidua ,Endothelial Cells ,Luteinizing Hormone ,Middle Aged ,CD56 Antigen ,Mice, Inbred C57BL ,medicine.anatomical_structure ,biology.protein ,Neural cell adhesion molecule ,L-selectin - Abstract
During the secretory phase of the menstrual cycle, a natural killer (NK) cell subset expressing cluster of differentiation (CD)56bright appears in the decidualizing uterus and remains until onset of menses. If pregnancy occurs, decidual NK cells increase to become the predominant uterine lymphocytes of early pregnancy. To elucidate mechanisms of CD56bright cell recruitment to the uterus, an in vitro adhesion assay was used to assess the effect of the menstrual cycle, as well as cycle-associated hormones on adhesive properties of human lymphocytes. Adhesion of human peripheral blood lymphocytes to pregnant mouse lymph nodes and Peyer's Patches tissue sections was constant throughout the cycle. When uterine tissue was used as the substrate, adhesive CD56+ cells were found only in decidua basalis. Adhesion increased at the LH surge. Adhesion was mediated through both L-selectin and alpha4-integrin-dependent mechanisms. Furthermore, we observed increased adhesive function in CD56+ cells from male donors which had been cultured with estradiol or LH compared with cell aliquots cultured without additives. Lymphocytes adherent to mouse uterine tissue were predominantly CD56bright, suggesting that peripheral NK cells may be actively recruited to the uterus in an important, brief endocrine-regulated fashion at the time of ovulation to establish the decidual NK population of early pregnancy.
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- 2005
16. Coordinate regulation of lymphocyte-endothelial interactions by pregnancy-associated hormones
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Qing Chen, Sharon S. Evans, Siamak Bashar, Wan-Chao Wang, Marianne J. van den Heuvel, Amanda Simpson, Sirirak Chantakru, and B. Anne Croy
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Male ,medicine.medical_specialty ,Endothelium ,Lymphocyte ,Immunology ,High endothelial venules ,Cell Communication ,Article ,Endometrium ,Mice ,Pregnancy ,Internal medicine ,Addressin ,medicine ,Cell Adhesion ,Immunology and Allergy ,Animals ,Humans ,Cell adhesion ,Lymphocyte homing receptor ,Progesterone ,Mice, Inbred BALB C ,biology ,Estradiol ,Cell adhesion molecule ,Estrogen Replacement Therapy ,CD56 Antigen ,Lymphocyte Subsets ,Killer Cells, Natural ,Mice, Inbred C57BL ,medicine.anatomical_structure ,Endocrinology ,Organ Specificity ,biology.protein ,Female ,Lymph ,Endothelium, Vascular ,Spleen - Abstract
Precursors of uterine NK cells home to the uterus during early pregnancy from multiple lymphohemopoietic sources. In mouse uterine tissue, pregnancy markedly up-regulates both L-selectin- and α4 integrin-dependent adhesion pathways for circulating human CD56bright cells, the phenotype of human uterine NK cells. Based on roles for these adhesion molecules in lymphocyte homing, we examined effects of pregnancy or the steroid hormones 17β-estradiol or progesterone on lymphocyte-endothelial interactions in secondary lymphoid tissues and in uterus. From preimplantation gestation day 3, specialized high endothelial venules in peripheral lymph nodes and Peyer’s patches supported elevated L-selectin and α4β7 integrin-dependent lymphocyte adhesion under shear throughout pregnancy, as compared with high endothelial venules of virgin or postpartum donors. Squamous endothelium from nonlymphoid tissue was not affected. Pregnancy-equivalent endothelial responses were observed in lymph nodes and Peyer’s patches from ovariectomized mice receiving 17β-estradiol and/or progesterone replacement therapy. Adhesion of human CD56bright cells to uteri from pregnant or hormone-treated ovariectomized mice was enhanced through L-selectin- and α4 integrin-dependent mechanisms and involved multiple vascular adhesion molecules including mucosal addressin cell adhesion molecule-1, VCAM-1, and peripheral lymph node addressin. Analysis of Tie2-green fluorescence protein transgenic mice demonstrated that CD56bright cells adhered primarily to vascular endothelium within the decidua basalis. Microdomain localization of adhesion involving large clusters of lymphocytes was induced on uteri from natural matings, but not pseudopregnancy. Steroid hormones also had independent effects on L-selectin function in splenic lymphocytes that mimicked physiological stimulation induced by pregnancy or fever-range temperatures. These results provide the first evidence for coordinated, organ-specific, steroid hormone-induced changes in lymphocyte homing mechanisms that could contribute to local and systemic immune responses during pregnancy.
- Published
- 2003
17. The Immediate Effect of High Power Laser on Quadriceps Muscle Performance in Male Football Players: A Single-Group, Pretest-Posttest Trial
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Elham Gorji, Seyed Mohsen Mir, Siamak Bashardoust Tajali, and Kazem Malmir
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Laser therapy ,Athletic performances ,Quadriceps muscles ,Football ,Medicine - Abstract
Introduction: The use of High Power Laser (HPL) has recently been emphasized in physiotherapy. Previous studies suggest that the prophylactic use of laser has ergogenic effects on athletic performance by increasing the contractile function of skeletal muscles. Recently, muscle function improvement is a new research idea in the field of laser therapy. Based on our knowledge, there are only two studies on the effects of HPL on muscle performance although with contradictory results. The purpose of this study was to investigate the effects of HPL on quadriceps muscle performance in male football players. Materials and Methods: Sixteen healthy male football players (Mean±SD age=18.53±7.2 years, Mean±SD body mass index=22.8±4.4 kg/m2) participated in a pretest-posttest study. The subjects received one session of HPL (808 nm, 80 j, 2 w) on quadriceps muscles. The Isometric Peak Torque (IPT), Single-Leg Hop Test (SLHT), and Y-balance Test (YBT) were measured at baseline and immediately after HPL. For statistical analysis, we used the paired sample t test. Results: Immediately after HPL, the IPT (P=0.001), SLHT (P=0.02), and YBT scores (P=0.001) significantly increased. Conclusion: The results of our study showed that immediate application of one session of HPL can improve IPT as well as functional tests. Although the sessions of laser application and assessment were limited and the sample size was small, it seems that HPL could improve muscle performance. Therefore, further research is warranted with large sample size and follow-up.
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- 2020
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18. Comparing Between the Effects of Dry Needling and Shock Wave in the Treatment of Trapezius Myofascial Pain
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Mehran Toghtamesh, Siamak Bashardoust Tajali, and Shohreh Jalaei
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Pain ,Range of motion ,Trigger point ,Upper trapezius muscle ,Dry needling ,Shock wave therapy ,Medicine - Abstract
Introduction: Musculoskeletal disorders are important causes of pain. Trigger points are one of the common reasons for myofascial pain. This study aimed to compare a single session of dry needling versus a single session of shock wave therapy on the level of pain and Range of Motion (ROM) in the people with Myofascial Pain Syndrome (MPS) of the upper trapezius muscle. Materials and Methods: Sixteen men with active trigger points of upper trapezius muscle were voluntarily attended in this study. They were randomly assigned into two groups. The patients were under a single session treatment of either dry needling or shock wave therapy. Level of pain (by Visual Analog Scale [VAS]) and active ROM of neck lateral flexion (by goniometer) were evaluated once before the treatment and immediately after the intervention. Results: The VAS scores and the neck ROMs were substantially improved at both groups of study immediately after the treatment (P0.05). Conclusion: Both dry needling and shock wave therapy can improve neck pain and ROM in patients with active trigger points in the upper trapezius muscle.
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- 2020
19. Effects of Low-Level Laser Irradiation and Dry Needling on the Symptoms of Myofascial Pain Syndrome: A Controlled Pilot Study
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Maryam Motavalian, Siamak Bashardoust Tajali, Behrouz Attarbashi Moghadam, and Seyedeh Zohreh Hosseini
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Myofascial pain syndrome ,Pain ,Trigger points ,Low-level laser ,Dry needling ,Medicine - Abstract
Introduction: This study aimed to compare the effects of Low-Level Laser Therapy (LLLT) combined with Dry Needling (DN) with DN alone on pain and neck disability index following myofascial pain syndrome. Materials and Methods: Sixteen women with active Trigger Points (TrPs) in their upper trapezius muscles participated in this study. They were divided into two groups: Experimental and control. The experimental group received one session of the DN plus the LLLT with 6 j/cm2 energy at their TrPs. The patients in the control group were under a similar procedure, but they did not receive any energy by the LLLT (placebo). The pain score was assessed before, immediately, and 48 hours after the treatment. Neck Disability Index (NDI) was assessed before and 48 hours after the treatment. Results: There was a significant improvement in pain intensity and NDI scores 48 hours after the treatment in both groups compared with the baseline scores (P
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- 2020
20. Application of Combined Laser and Compression Therapy on the Pain and Level of Disability on Trigger Points in Upper Trapezius Muscle
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Saeed Rezaei, Azadeh Shadmehr, Siamak Bashardoust Tajali, Behrooz Attarbashi Moghadam, and Shohreh Jalaei
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Myofascial pain syndrome ,Pain ,Trigger points ,Laser therapy ,Medicine - Abstract
Introduction: Musculoskeletal disorders are among the main causes of disability in modern life. Myofascial trigger points are very common among musculoskeletal disorders and may occur through ordinary common activities. This study aimed to determine the combined effects of laser therapy and Ischemic Compression (IC) on the treatment of Myofascial Trigger Points (MTrPs) at the upper trapezius muscle. Materials and Methods: Twenty men with at least one active trigger point at their upper trapezius muscle voluntarily participated in this study. Trigger points were under treatment of laser irradiation (6 Joules per point) and also ischemic compression. Treatment approaches were applied over the pain point every other day for 5 sessions in 10 days. Neck disability index, pain intensity by visual analog scale, pressure pain threshold by algometry, and cervical lateral flexion by goniometer were assessed and recorded before the intervention, and immediately after the last session. Results: At the end of treatment, statistically significant improvements were seen in the neck disability index, VAS value, pressure pain threshold, and cervical lateral flexion. VAS values of the treatment and control groups were compared with the baseline (P
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- 2020
21. Effectiveness of Dry Needling for the Management of Plantar Fasciitis: A Review Study
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Saman Salehi, Azadeh Shadmehr, Gholamreza Olyaee, Siamak Bashardoust Tajali, and Seyed Mohsen Mir
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Dry needling ,Trigger point ,Myofascial trigger point ,Plantar fasciitis ,Heel pain ,Plantar fascia ,Medicine - Abstract
Introduction: Plantar fasciitis (PF) is an overuse syndrome as it develops over time. It is most frequently seen in both the non-athletic and athletic populations. PF is a multifactorial and self-limiting disorder that several factors are involved in its onset. Many well-established treatments are available for plantar heel pain. The purpose of this review is to determine the effectiveness of dry needling for the management of PF. Materials and Methods: This article is a review study, in which we present the studies that compare dry needling with other treatments for the management of plantar heel pain. We included all of the studies on patients with plantar heel pain and plantar fasciitis that investigated the effects of dry needling. Finally, seven articles were included in this review. The study designs were randomized controlled, quasi-experimental, and case-control. The Physiotherapy Evidence-based Database (PED) scale was used to measure the methodological quality of the studies. Results: The PEDro scoring of the articles ranged between 2.10-7.10. The results of this review show that dry needling may be useful in improving the pain of individuals with plantar heel pain and plantar fasciitis. Conclusion: Further high-quality research studies are needed to determine the effectiveness of dry needling in the management of plantar heel pain. Because a variety of protocol treatments of dry needling were used in the studies, we cannot recommend dry needling schedule prescriptions for the management of individuals with plantar heel pain and plantar fasciitis.
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- 2019
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22. Immediate Effects of Plyometric Exercises on Speed, Balance and Jump Ability of Amateur Futsal Players: A Randomized Control Trial
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Nafiseh Zekri, Siamak Bashardoust Tajali, and Nastaran Ghotbi
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Plyometric exercise ,Postactivation potentiation ,Athletic performance ,Futsal ,Medicine - Abstract
Introduction: The rate of football-related traumas is high. However, greater levels of fitness may decrease the probability of these injuries. Researchers believe that plyometric training can have significant short-term results. This study aimed to investigate the effects of plyometric exercises on athletic performance (speed, balance, and vertical jump ability) of male amateur futsal players. Materials and Methods: Thirty male amateur futsal players were randomly divided into control and plyometric groups. All participants went through 15 minutes of standard warm-up activity, and then they were asked to perform the tests. The athletes of the plyometric group also completed three rounds of plyometric jumps and then were assessed 3, 10, 15 and 20 minutes after the warm up. The athletes of the control group were evaluated 3, 10, and 15 minutes immediately after the standard warm-up activity. Results: The study findings indicated an overall improvement in balance and vertical jump scores of amateur futsal players following plyometric exercises (P
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- 2019
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23. The Effect of Laser Therapy and Ischemic Compression on Active Trigger Points in Upper Trapezius Muscle
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Saeed Rezaei, Azadeh Shadmehr, Siamak Bashardoust Tajali, Behrooz Attarbashi Moghadam, and Shohreh Jalaei
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Myofascial pain syndromes ,Pain ,Trigger points ,Laser therapy ,Manual therapy ,Medicine - Abstract
Introduction: Myofascial Pain Syndrome (MPS) is a common muscular disorder characterized by a referral pain to a particular area after irritating the myofascial trigger point. This study aimed to determine the combined treatment effect of laser therapy and ischemic compression of an active myofascial trigger point in the upper trapezius muscle. Materials and Methods: This is a clinical trial study conducted on 15 subjects with Active Trigger Points (ATPs). In one session, 15 subjects received laser therapy and ischemic compression. The assessment was done immediately after the treatment. We used the visual analog scale for the measurement of pain intensity, algometry (FG-5020, Taiwan made) for pressure pain threshold, and goniometer for cervical lateral flexion. Results: The cervical lateral flexion after the intervention was significantly higher than that before the intervention (P
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- 2019
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24. Effects of Low-Level Laser Versus Laser Acupuncture in Patients With Knee Osteoarthritis: A Randomized Controlled Trial
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Ali Lafta Mezaal, Siamak Bashardoust Tajali, Gholamreza Olyaei, Shohreh Jalaie, and Saddi Thweab Alwatifi
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Low-Level Laser ,Laser acupuncture ,Knee ,Osteoarthritis ,Medicine - Abstract
Introduction: Osteoarthritis (OA) is one of the common causes of disabilities in adults. The prevalence of Knee Osteoarthritis (KOA) is approximately 4.9% among people over 26, 16.7% among people over 45, and 12.1% among people over 60 years old. This study aims to determine the effects of Low-Level Laser Therapy (LLLT) and laser acupuncture in decreasing pain and increasing functional activity in patients with subacute and chronic KOA. Materials and Methods: In this randomized, single-blind, controlled study, the patients with grades 2 and 3 primary KOA were assigned into two experimental groups (active low-level laser and acupuncture laser) and one control group (infrared & exercise). The patients in the experimental group I (n=23) were under low-level Ga-Al–As diode laser, 830-nm continuous waves, and received laser irradiation of 30 mW/cm2 power density, 3 mW output power, 0.1 cm2 spot size, with a total dose of 18 J and for 10 minutes on 6 acupuncture points (SP10, ST34, ST35, GB34, Xiyan, SP9) around the knee in each session. The patients in the experimental group II (n=23) received 3 J power irradiation in each cm2 in a gridding technique over a triangle-like surface of 15 cm2 over the medial, lateral, and anterior sides of the knee with a total energy density of 45 J/15 cm2 for each session. Laser therapy was applied 5 times per week for a period of two weeks (10 sessions in total). The patients in the control group (group III) were under conventional physiotherapy (superficial heat therapy and isometric knee exercises for 15 minutes every day for a similar period (10 sessions in 2 weeks). The outcome study measures were pain level at rest rated by Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Osteoarthritis index (WOMAC), and Short Form of McGill Pain Questionnaire (SF-MPQ). In addition, active knee flexion and extension Range of Motions (ROMs) were measured too. These variables were evaluated at the baseline time, before the intervention, and after the intervention, on the final day of the intervention. Results: Based on statistical outcomes, a significant pain reduction by NRS and McGill, an increase in functional activity by WOMAC as well as an increase in the Range of Motion of the knee were observed in three study groups after 10 sessions. However, the result of ANOVA test showed significant difference in pain reduction among three groups and the post hoc Least Significant Difference (LSD) test showed the significant difference between laser acupuncture and conventional laser groups with the control group; the largest improvement was found in Group I. In terms of functional activity, the post hoc LSD test showed the significant difference between conventional laser and laser acupuncture groups with the control group; the largest improvement was found in Group II. No significant difference was observed among the three groups with regard to the mean values of active knee flexion and extension. Conclusion: Laser acupuncture and conventional laser are more effective in reducing pain and increasing functional activity in patients with KOA compared to conventional treatment. Clinically, laser acupuncture would appear to be superior in pain reduction.
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- 2019
25. Research Paper: Immediate Effects of Maitland Mobilization and Mulligan Techniques on Flexion and Extension Range of Motion in Patients With Chronic Nonspecific Low Back Pain: A Randomized Pilot Study
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Mohammad Javaherian, Siamak Bashardoust Tajali, Behrouz Attarbashi Moghaddam, Abbas Ali Keshtkar, and Maryam Azizi
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Maitland mobilization ,Sustained natural apophyseal glide ,SNAG ,Nonspecific chronic low back pain ,Medicine - Abstract
Introduction: Nonspecific Chronic Low Back Pain (NSCLBP) is one of the most common musculoskeletal disorders among different societies. Manual therapists use different approaches for NSCLBP management and or treatment. Comparing manual techniques is a considerable controversial debate among treatment approaches. This study aimed at comparing the immediate effects following Maitland mobilization technique and Mulligan Sustained Natural Apophyseal Glide (SNAG) on flexion and extension in patients with the NSCLBP. Materials and Methods: Eighteen volunteers with NSCLBP were randomly divided into three groups: Posteroanterior (PA) mobilization, SNAG, and Sham SNAG. The PA mobilization techniques (Grade III) were performed on prone lying position (four sets of four repetitions; last 30 seconds for each technique). The SNAG techniques were performed accompanying with active flexion in sitting position (four sets of six repetitions). The sham SNAG technique was applied in sitting position while therapist touched gently patients’ backs (three sets of four repetitions). Flexion and extension Range of Motions (ROMs) were measured before and immediately after applied interventions (by inclinometer). Results: Within group analysis showed significant changes of flexion and extension in ROMs in SNAG and PA mobilization groups. Between groups analysis pointed out significant difference between the SNAG and placebo groups after interventions. Conclusion: Our results revealed increased flexion ROM following the SNAG technique and increased extension ROM after Maitland PA mobilization. However, our limited sample size might influence final results. More studies with larger sample size will be suggested.
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- 2017
26. Effects of Gallium Arsenide Laser on Pain and Grip Strength in Patients With Tennis Elbow
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Gholamreza Olyaei, Siamak Bashardoust Tajali, Behrouz Ataye Mansouri, and Reza Shafipoor
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High power laser ,Ga-As laser ,Tennis elbow ,Pain ,Grip strength ,Medicine - Abstract
Introduction: Tennis elbow (Lateral Epicondylitis) is one the most common elbow and arm musculoskeletal disorders. About 1% to 3% of active population in modern societies suffer from tennis elbow. Tennis elbow is usually caused by repetitive activities of hand and wrist, especially wrist extension and forearm supination. This research aimed to study high and also medium power gallium arsenide (Ga-As) laser irradiation on improving pain and grip strength (functional mobility) in patients with tennis elbow. Material and Methods: Thirty female [Mean(SD) age: 49(2.3) y] patients with acute tennis elbow were recruited for this study. The patients were randomly divided into two groups based on random allocation table. Group A (15 patients) had been received 10 J/cm2 under a 0.5 W beam medium power Ga-As laser irradiation of 980 nm wave length. Group B (15 patients) had been received same energy density under 2 W beam high Ga-As laser irradiation with the same wavelength. Laser irradiation was performed on a 9 cm2 surface of lateral elbow epicondyle based on Grid laser application technique. The patients were under treatment for 10 sessions every other day. The outcome measures of pain at rest and ring finger extension against loading, grip strength and hand function were recorded and analyzed in a pre- and post-setting. The pain severity was measured by VAS (Visual Analog Scale) and McGill questionnaire and upper extremity function was measured by DASH questionnaire. Results: Significant pain reduction was observed in resting position and ring finger extension against loading after application of both high and medium power (980 nm, 0.5-2 W) laser therapy (P
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- 2017
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27. Effects of Intramuscular Electrical Stimulation on Symptoms Following Trigger Points; A Controlled Pilot Study
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Monavar Hadizadeh, Siamak Bashardoust Tajali, Behrouz Attarbashi Moghadam, Shohreh Jalaie, and Mahnaz Bazzaz
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Myofascial pain syndrome ,Intramuscular electrical stimulation ,Dry needling ,Trigger point ,Upper trapezius. ,Medicine - Abstract
Introduction: Myofascial Pain Syndrome (MPS) is a common disorder of musculoskeletal system. About one third of the people with musculoskeletal disorders have been diagnosed as having MPS. It is a painful condition caused by trigger points. A variety of treatment approaches are used to cure MPS and its associated disorders. This study aimed to investigate the effects of single session Intramuscular Electrical Stimulation (IMES) through dry needling on pain and Range Of Motion (ROM) following trigger points in upper trapezius. Material and Methods: Sixteen volunteers with active trigger points in upper trapezius were randomly divided into two groups: 1) the IMES treatment group (8 females) and 2) placebo group (8 females). In the IMES group, trigger points of the affected side were injected through dry needling, then a burst current (2 Hz) was applied on the muscle while the electrical stimulation steadily increases to form a pain free contraction for the patient. In placebo group, the procedure was exactly the same but there was no applied electrical stimulation through dry needling. Pain sensation by Visual Analog Scale (VAS) and cervical flexion ROM were measured before treatment, immediately after treatment and one week later by another blinded researcher. Results: VAS scores showed improvement in both groups at the end of the treatment session and also one week later. There was no significant difference between the groups; IMES and placebo in terms of the VAS after treatment session. However, the pain scores were substantially decreased in the IMES group one week after the intervention. The ROMs were significantly lower in placebo group one week after treatment. There was no significant correlation between improvement and duration of symptoms. Conclusion: Both IMES and placebo methods might be effective in relieving symptoms of patients with the MPS in upper trapezius; however, patients following the IMES treatment showed higher level of improvement during one week after the intervention. Further relevant studies with higher number of volunteers and different treatment protocols are necessary to get high quality evidence.
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- 2017
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