45 results on '"Siddiqui, Maqbool A."'
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2. The triphosphate of β- d-4′- C-ethynyl-2′,3′-dideoxycytidine is the preferred enantiomer substrate for HIV reverse transcriptase
3. Interactions of conformationally biased north and south 2'-fluoro-2',3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase
4. Adenosine deaminase prefers a distinct sugar ring conformation for binding and catalysis: kinetic and structural studies
5. HIV-1 reverse transcriptase can discriminate between two conformationally locked carbocyclic AZT triphosphate analogues
6. Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state
7. Glycoamino Acid Analogues of the Thomsen–Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides
8. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-like North Bicyclo[3.1.0]hexane Pseudosugars
9. Synthesis and hybridization properties of modified oligodeoxynucleotides carrying non-natural bases
10. Recognition of the Thomsen-Friedenreich Pancarcinoma Carbohydrate Antigen by a Lamprey Variable Lymphocyte Receptor
11. A Direct, Efficient Method for the Preparation of siRNAs Containing Ribo-like North Bicyclo[3.1.0]hexane Pseudosugars
12. 4′-C-Methyl-2′-Deoxyadenosine and 4′-C-Ethyl-2′-Deoxyadenosine Inhibit HIV-1 Replication
13. Using conformationally locked nucleosides to calibrate the anomeric effect: implications for glycosyl bond stability
14. ChemInform Abstract: The “β-Fluorine Effect” in the Non-Metal Hydride Radical Deoxygenation of Fluorine-Containing Nucleoside Xanthates.
15. Contrasting Behavior of Conformationally Locked Carbocyclic Nucleosides of Adenosine and Cytidine as Substrates for Deaminases
16. Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
17. Activation of p16 Gene Silenced by DNA Methylation in Cancer Cells by Phosphoramidate Derivatives of 2′-Deoxyzebularine
18. The Nucleoside Analogs 4′C-Methyl Thymidine and 4′C-Ethyl Thymidine Block DNA Synthesis by Wild-type HIV-1 RT and Excision Proficient NRTI Resistant RT Variants
19. A 4‘-C-Ethynyl-2‘,3‘-Dideoxynucleoside Analogue Highlights the Role of the 3‘-OH in Anti-HIV Active 4‘-C-Ethynyl-2‘-deoxy Nucleosides
20. Conformationally Constrained Analogues of Diacylglycerol. 24. Asymmetric Synthesis of a Chiral (R)-DAG-Lactone Template as a Versatile Precursor for Highly Functionalized DAG-Lactones
21. Methanocarba Analogues of Purine Nucleosides as Potent and Selective Adenosine Receptor Agonists
22. ChemInform Abstract: Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)‐Atom in the Key Hydration Step of Adenosine Deaminase.
23. Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1 Receptor Ligands
24. The “β-Fluorine Effect” in the Non-Metal Hydride Radical Deoxygenation of Fluorine-Containing Nucleoside Xanthates
25. Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)-Atom in the Key Hydration Step of Adenosine Deaminase
26. cycloSal-Pronucleotides of 2‘-Fluoro-ara- and 2‘-Fluoro-ribo-2‘,3‘- dideoxyadenosine as a Strategy to Bypass a Metabolic Blockade
27. Conformationally Restricted Nucleosides. The Reaction of Adenosine Deaminase with Substrates Built on a Bicyclo[3.1.0]hexane Template
28. Lessons from the Pseudorotational Cycle: Conformationally Rigid AZT Carbocyclic Nucleosides and Their Interaction with Reverse Transcriptase
29. A new synthetic approach to the clinically useful, anti-HIV-active nucleoside, 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine (β-FddA). Introduction of a 2′-β-fluoro substituent via inversion of a readily obtainable 2′-α-fluoro isomer
30. Conformational Analysis of Nucleosides Constructed on a Bicyclo[3.1.0]hexane Template. Structure-Antiviral Activity Analysis for the Northern and Southern Hemispheres of the Pseudorotational Cycle
31. Conformational analysis of the complete series of 2′ and 3′ monofluorinated dideoxyuridines
32. Lipophilic, Acid-Stable, Adenosine Deaminase-Activated Anti-HIV Prodrugs for Central Nervous System Delivery. 3. 6-Amino Prodrugs of 2‘-β-Fluoro-2‘,3‘-dideoxyinosine
33. Synthesis, Conformational Analysis, and Biological Activity of a Rigid Carbocyclic Analogue of 2′-Deoxy Aristeromycin Built on a Bicyclo[3.1.0]hexane Template
34. Nucleosides with a Twist. Can Fixed Forms of Sugar Ring Pucker Influence Biological Activity in Nucleosides and Oligonucleotides?
35. Lipophilic, Acid-Stable, Adenosine Deaminase-Activated Anti-HIV Prodrugs for Central Nervous System Delivery. 2. 6-Halo- and 6-Alkoxy Prodrugs of 2'-.beta.-Fluoro-2',3'-dideoxyinosine
36. A diastereoselective synthesis of (S,S)-α-fluoro-2,2-dimethyl-1,3-dioxolane-4-propanoic acid methyl ester, a key intermediate for the preparation of anti-HIV effective fluorodideoxynucleosides
37. Chemistry and Anti-HIV Activity of 2′-β-Fluoro-2′,3′-dideoxyguanosine
38. Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines
39. 2-Mercaptoaldehyde dimers and 2,5-dihydrothiophenes from 1,3-oxathiolan-5-ones.
40. A More Expedient Approach to the Synthesis of Anti-HIV-Active 2,3-Dideoxy-2-fluoro-β-D-threo-pentofuranosyl Nucleosides
41. Reduction and alkylation of 1,3-oxathiolan-5-ones as a route to alpha-mercaptoaldehydes
42. Alkylation and aldol condensation reactions of 1,3-oxathiolanones
43. ChemInform Abstract: The 'β-Fluorine Effect' in the Non-Metal Hydride Radical Deoxygenation of Fluorine-Containing Nucleoside Xanthates.
44. What are the consequences of freezing the anomeric effect in nucleosides?
45. Recognition of the Thomsen-Friedenreich Pancarcinoma Carbohydrate Antigen by a Lamprey Variable Lymphocyte Receptor.
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