1. Chromosomal anomaly of 6q in chronic myelogenous leukemia (CML).
- Author
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Srivastava AK, Gruppo RA, and Siegrist CW
- Subjects
- Adolescent, Adult, Bone Marrow pathology, Chromosome Banding, Humans, Karyotyping, Leukemia, Myeloid pathology, Male, Chromosome Aberrations genetics, Chromosome Disorders, Chromosomes, Human, 6-12 and X, Leukemia, Myeloid genetics
- Abstract
Anomalies of chromosome 6q, along with other chromosomal anomalies, are described in the bone marrow cells of two patients with chronic myelogenous leukemia (CML). One patient a 14-year-old male, developed the karyotype 46,XY,t(1;6)(p36;q15),del(3)(q25), del(17)(p11),? inv(17)(q12q24) during blastic crisis of his disease. The other patient, a 24-year-old male, had the karyotype 46,XY,del(6)(q13),5(9;22)(q34;q11) during the early phase of his disease and evolution of i(17q) in the karyotype late in the disease.
- Published
- 1981
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