Search

Your search keyword '"Silvia Puddu"' showing total 4 results
Start Over Author "Silvia Puddu"
4 results on '"Silvia Puddu"'

1. Differences in surgical outcomes between cervical goiter and retrosternal goiter: an international, multicentric evaluation

Author

Federico Cappellacci, Gian Luigi Canu, Leonardo Rossi, Andrea De Palma, Maria Mavromati, Paulina Kuczma, Giacomo Di Filippo, Eleonora Morelli, Marco Stefano Demarchi, Paolo Brazzarola, Gabriele Materazzi, Pietro Giorgio Calò, Fabio Medas, our Mediastinal Goiter Study Collaborative Group, Cristina Soddu, Francesco Casti, Miriam Biancu, Silvia Puddu, Francesca Morinello, Giovanni Lazzari, Dorin Serbusca, Bernard Gjeloshi, Mariangela Caradonna, and Luisa Sacco

Subjects
mediastinal goiter, thyroid surgery, cervicomediastinal goiter, thyroid surgery morbidity, retrosternal goiter, Surgery, RD1-811
Abstract

IntroductionGoiter is a common problem in clinical practice, representing a large part of clinical evaluations for thyroid disease. It tends to grow slowly and progressively over several years, eventually occupying the thoracic inlet with its lower portion, defining the situation known as retrosternal goiter. Total thyroidectomy is a standardized procedure that represents the treatment of choice for all retrosternal goiters, but when is performed for such disease, a higher risk of postoperative morbidity is variously reported in the literature. The aims of our study were to compare the perioperative and postoperative outcomes in patients with cervical goiters and retrosternal goiters undergoing total thyroidectomy.MethodsIn our retrospective, multicentric evaluation we included 4,467 patients, divided into two groups based on the presence of retrosternal goiter (group A) or the presence of a classical cervical goiter (group B).ResultsWe found statistically significant differences in terms of transient hypoparathyroidism (19.9% in group A vs. 9.4% in group B, p

Published
2024
Full Text
View/download PDF

2. Risk factors for postoperative cervical haematoma in patients undergoing thyroidectomy: a retrospective, multicenter, international analysis (REDHOT study)

Author

Gian Luigi Canu, Fabio Medas, Federico Cappellacci, Leonardo Rossi, Benard Gjeloshi, Luca Sessa, Francesco Pennestrì, Reza Djafarrian, Maria Mavromati, George Kotsovolis, Ioannis Pliakos, Giacomo Di Filippo, Giovanni Lazzari, Carla Vaccaro, Martina Izzo, Francesco Boi, Paolo Brazzarola, Francesco Feroci, Marco Stefano Demarchi, Theodossios Papavramidis, Gabriele Materazzi, Marco Raffaelli, Pietro Giorgio Calò, REDHOT Study Collaborative Group, Giacomo Anedda, Cristina Soddu, Francesco Casti, Miriam Biancu, Silvia Puddu, Selina Russo, Andrea De Palma, Francesco Pignatelli, Elisa Loguercio, Livia Palmieri, Giulia Salvi, Priscilla Francesca Procopio, Eleonora Morelli, Dorin Serbusca, Alessio Biagio Filippo Giordano, Giulia Fiorenza, Sophie Leboulleux, and Nathalie Massé

Subjects
thyroidectomy, thyroid surgery, cervical haematoma, bleeding, risk factors, complications, Surgery, RD1-811
Abstract

BackgroundPostoperative cervical haematoma represents an infrequent but potentially life-threatening complication of thyroidectomy. Since this complication is uncommon, the assessment of risk factors associated with its development is challenging. The main aim of this study was to identify the risk factors for its occurrence.MethodsPatients undergoing thyroidectomy in seven high-volume thyroid surgery centers in Europe, between January 2020 and December 2022, were retrospectively analysed. Based on the onset of cervical haematoma, two groups were identified: Cervical Haematoma (CH) Group and No Cervical Haematoma (NoCH) Group. Univariate analysis was performed to compare these two groups. Moreover, employing multivariate analysis, all potential independent risk factors for the development of this complication were assessed.ResultsEight thousand eight hundred and thirty-nine patients were enrolled: 8,561 were included in NoCH Group and 278 in CH Group. Surgical revision of haemostasis was performed in 70 (25.18%) patients. The overall incidence of postoperative cervical haematoma was 3.15% (0.79% for cervical haematomas requiring surgical revision of haemostasis, and 2.35% for those managed conservatively). The timing of onset of cervical haematomas requiring surgical revision of haemostasis was within six hours after the end of the operation in 52 (74.28%) patients. Readmission was necessary in 3 (1.08%) cases. At multivariate analysis, male sex (P

Published
2023
Full Text
View/download PDF

3. Design and function of an electron mobility spectrometer with a thick gas electron multiplier

Author

Anthony J. Waker, Silvia Puddu, and Gloria M. Orchard

Subjects
Physics, Nuclear and High Energy Physics, Electron mobility, Spectrometer, 010308 nuclear & particles physics, business.industry, Electron, 01 natural sciences, 030218 nuclear medicine & medical imaging, Anode, 03 medical and health sciences, 0302 clinical medicine, Volume (thermodynamics), 0103 physical sciences, Gas electron multiplier, Optoelectronics, Gas detector, Detectors and Experimental Techniques, business, Instrumentation, Voltage
Abstract

The design and function of an electron mobility spectrometer (EMS) including a thick gas electron multiplier (THGEM) is presented. The THGEM was designed to easily be incorporated in an existing EMS to investigate the ability to detect tritium in air using a micropattern gas detector. The THGEM and a collection plate (anode) were installed and the appropriate circuitry was designed and connected to supply the required voltages to the THGEM-EMS. An alpha source ( 241 Am) was used to generate electron-ion pairs within the gas-filled sensitive volume of the EMS. The electrons were used to investigate the THGEM-EMS response as a function of applied voltage to the THGEM and anode. The relative gas-gain and system resolution of the THGEM-EMS were measured at various applied voltage settings. It was observed a potential difference across the THGEM of +420 V and potential difference across the induction region of +150 V for this EMS setup resulted in the minimum voltage requirements to operate with a stable gain and system resolution. Furthermore, as expected, the gain is strongly affected not only by the potential difference across the THGEM, but also by the applied voltage to the anode and resulting potential difference between the THGEM and anode.

Published
2016

4. Urinary metabolomics of bronchopulmonary dysplasia (BPD): preliminary data at birth suggest it is a congenital disease

Author

Luigi Atzori, Maria Cristina Pintus, Gustavo Rocha, Mauro Stronati, Maria Antonietta Marcialis, Giovanni Corsello, Michele Mussap, Vassilios Fanos, Antonio Noto, Corrado Moretti, Silvia Puddu, Hercília Guimarães, Francesca Serraino, Milena Lussu, Serafina Lacerenza, Mario Giuffrè, Paola Papoff, Fanos, V, Pintus, M, Lussu, M, Atzori, L, Noto, A, Stronati, M, Guimaraes, H, Marcialis, MA, Rocha, G, Moretti, C, Papoff, P, Lacerenza, S, Puddu, S, Giuffrè, M, Serraino, F, Mussap, M, and Corsello, G

Subjects
Male, Pediatrics, medicine.medical_specialty, Neonatal intensive care unit, Birth weight, Urinary system, Proton Magnetic Resonance Spectroscopy, metabolite, Gestational Age, Disease, Metabolomics, Settore MED/38 - Pediatria Generale E Specialistica, Intensive Care Units, Neonatal, medicine, Humans, Infant, Very Low Birth Weight, multivariate statistical analysis, business.industry, Infant, Newborn, 1H-NMR, Obstetrics and Gynecology, Gestational age, medicine.disease, Bronchopulmonary dysplasia, Low birth weight, Pediatrics, Perinatology and Child Health, Metabolome, Female, medicine.symptom, business, Biomarkers, Infant, Premature, metabolomic
Abstract

Objective: Bronchopulmonary dysplasia (BPD) or chronic lung disease is one of the principal causes of mortality and morbidity in preterm infants. Early identification of infants at the greater risk of developing BPD may allow a targeted approach for reducing disease severity and complications. The trigger cause of the disease comprehends the impairment of the alveolar development and the increased angiogenesis. Nevertheless, the molecular pathways characterizing the disease are still unclear. Therefore, the use of the metabolomics technique, due to the capability of identifying instantaneous metabolic perturbation, might help to recognize metabolic patterns associated with the condition. METHODS: The purpose of this study is to compare urinary metabolomics at birth in 36 newborns with a gestational age below 29 weeks and birth weight

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results