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20. Dosimetry

Author

Tunér, Jan, primary, Ribeiro, Martha Simões, additional, and Simões, Alyne, additional

Published
2015
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25. Aplicación del láser de baja potencia para analgesia de la odinofagia causada para radioterapia de cabeza y coello: Reporte de series de casos clínicos

Author

Grando, Liliane, Mituuti, Cláudia, Santos, Aira, Ghidini, Gabriela, Smiderle, Fabiane, Simões, Alyne, and Lisboa, Mariáh

Abstract

Objective: To propose the use of extraoral laser therapy to treat odynophagia associated with radioinduced hypopharyngeal mucositis. Odynophagia is characterized by swallowing pain, often requiring diet changes, which directly impacts the patient’s quality of life. Material and Methods: The investigation was an observational descriptive study with case series report. Was performed application of extraoral photobiomodulation for three oncologic patients with odynophagia associated with oral and hypopharyngeal mucositis radioinduced, with low-level laser therapy (Therapy XT DMC®) with λ808nm, 100mW power and 4J energy, 40 seconds per point. Reports of three patients who underwent treatment were collected, transcribed and reviewed qualitatively. The laser application points were proposed based on a previous anatomical study in cadavers, which sought to identify the best area of application of the extraoral laser in the cervical region to reach the hypopharynx. Results: Patients reported reduced odynophagia and greater comfort with the use of this extraoral laser therapy to the hypopharynx in the carotid trigone. Conclusion: The carotid trigone was the best extraoral region for laser application to reach the hypopharyngeal region. The laser therapy protocol applied in this region brought comfort to the patients assessed. Further studies are needed to assess the analgesic capacity of this treatment. Objetivo: Proponer el uso del láser de baja potencia extraoral para el tratamiento de la odinofagia asociada a mucositis hipofaríngea radio inducida. La odinofagia se caracteriza por dolor al tragar, que a menudo requiere cambios en la dieta, lo que impacta directamente en la calidad de vida del paciente. Material y métodos: La investigación fue un estudio observacional descriptivo con reporte de series de casos clínicos. Se realizó aplicación de fotobiomodulación extraoral para tres pacientes con odinofagia asociada a mucositis oral e hipofaríngea. Se utilizó la terapia con láser de baja potencia (Therapy XT DMC®), con λ808nm, 100 mW de potencia y 4J de energía, 40 segundos por punto. Se recopilaron, transcribieron y revisaron cualitativamente los informes de tres pacientes que se sometieron a tratamiento. Los puntos de aplicación del láser se propusieron a partir de un estudio anatómico previo en cadáveres, que buscó identificar la mejor zona de aplicación del láser extraoral en la región cervical para llegar a la hipofaringe. Resultados: Los pacientes informaron una reducción de la odinofagia y una mayor comodidad con el uso de este tratamiento en el trígono carotídeo. Conclusión: El trígono carotídeo resultó ser la mejor región extraoral para la aplicación de láser para llegar a la región hipofaríngea. El uso de láser de baja potencia aplicado en esta región redujo la odinofagia de los pacientes. Se necesitan más estudios para evaluar la capacidad analgésica de este tratamiento.

Published
2021

35. Long-term survival of cancer patients after photobiomodulation therapy for prevention and treatment of oral mucositis.

Author

Paiva, Deise Luciane, Oliveira, Valdecir Rodrigues, Bagnato, Vanderlei Salvador, and Simões, Alyne

Abstract

• Photobiomodulation therapy (PBMT) associated with oncological treatments has increased the survival of patients with head and neck cancer. • Head and neck cancer patients showed better survival after PBMT for oral mucositis which as caused by the cancer therapy. • The number of PBMT sessions associated with cancer treatments positively influenced the survival of patients with head and neck cancer. Photobiomodulation therapy (PBMT) has been employed for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing treatment. However, information about the survival of patients receiving PBMT is still lacking. Therefore, the aim of this study was to correlate the survival of patients who either received or did not receive PBMT, combined with cancer treatments, and to assess whether the number of PBMT sessions had a positive impact on survival. The records of 751 patients seen at Hospital de Caridade São Vicente de Paulo diagnosed with head and neck cancer, treated by D.L.P., the sole operator of PBMT, between 2000 and 2016, were analyzed. The median survival rates were compared by analyzing diagnostic staging, the combination of cancer treatments, and the number of PBMT sessions. Correlation analyses were performed to assess the interactions between the number of PBMT sessions and survival. PBMT increased survival by 55.14 %, from 1.07 (Without PBMT) to 1.66 years (With PBMT) for the total population and more significantly in Group 41 (stages III and IV, radiation therapy/chemotherapy, with more than five PBMT sessions), the median survival value of 1.83 years, which represents a 66.36 % higher survival rate. In all the analyzed populations, the larger number of sessions was associated with better survival. In terms of survival, advanced stages III and IV almost equated with stages I and II in the absence of PBMT. PBMT seems to interfere with the survival of patients with head and neck cancer, corroborating its recommendation for the treatment of mucositis, but further research is needed to investigate possible synergistic effects between PBMT and cancer treatments. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Does the hybrid light source (LED/laser) influence temperature variation on the enamel surface during 35% hydrogen peroxide bleaching? A randomized clinical trial.

Author

Moreira de Freitas, Patricia, Menezes, Andressa Nery, Costa da Mota, Ana Carolina, Simões, Alyne, Medeiros Mendes, Fausto, Neves Lago, Andrea Dias, Soares Ferreira, Leila, and Ramos-Oliveira, Thayanne Monteiro

Subjects
HYDROGEN peroxide, DENTAL enamel, TOOTH whitening, TOOTH sensitivity, COLOR, LASERS, LIGHT, TEMPERATURE, RANDOMIZED controlled trials, VISUAL analog scale, TREATMENT effectiveness, DATA analysis software, NULL hypothesis, PHYSIOLOGY
Abstract

Objective: The present study investigated how a hybrid light source (LED/laser) influences temperature variation on the enamel surfaces during 35% hydrogen peroxide (HP) bleaching. Effects on the whitening effectiveness and tooth sensitivity were analyzed. Method and Materials: Twenty-two volunteers were randomly assigned to two different treatments in a split-mouth experimental model: group 1 (control), 35% HP; group 2 (experimental), 35% HP + LED/laser. Color evaluation was performed before treatment, and 7 and 14 days after completion of bleaching, using a color shade scale. Tooth sensitivity was assessed using a visual analog scale (VAS; before, immediately, and 24 hours after bleaching). During the bleaching treatment, thermocouple channels positioned on the tooth surfaces recorded the temperature. Data on color and temperature changes were subjected to statistical analysis (α = 5%). Tooth sensitivity data were evaluated descriptively. Results: Groups 1 and 2 showed mean temperatures (± standard deviation) of 30.7 ± 1.2°C and 34.1 ± 1.3°C, respectively. It was found that there were statistically significant differences between the groups, with group 2 showing higher mean variation [P < .0001). The highest temperature variation occurred for group 2, with an increase of 5.3°C at the enamel surface. The color change results showed no differences in bleaching between the two treatment groups (P = .177). The variation of the average temperature during the treatments was not statistically associated with color variation (P = .079). Immediately after bleaching, it was found that 36.4% of the subjects in group 2 had mild to moderate sensitivity. In group 1, 45.5% showed moderate sensitivity. In both groups, the sensitivity ceased within 24 hours. Conclusion: Hybrid light source (LED/laser) influences temperature variation on the enamel surface during 35% HP bleaching and is not related to greater tooth sensitivity. [ABSTRACT FROM AUTHOR]

Published
2016
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