Our study focused on patients undergoing dialysis, in order to assess the relations of influence between self-efficiency, anxiety, depression and compliance to treatment for these patients. Research group: 72 patients, both sexes, aged between 45 and 70, from Gral Dialysis Center in Bucharest, (under treatment 2 to 7 years). Methods Self-Efficiency Scale (SES), HADS, SF-36. Results were interpreted psycho-clinically and statistically-mathematically. We identified differences between groups of age and sexes – considering the period of time under treatment. Results confirmed our hypotheses; the information we got became rules of conduct for the patients with renal chronic diseases - the role of the family proved important in reaching bio-psycho-social balance in the life of the sick.